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Cited by 107Coffee research and impactsNutritional Studies and DietAlcohol Consumption and Health Effects

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Coffee consumption and risk of total and cardiovascular mortality among patients with type 2 diabetes

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Bidel, S., Hu, G., Qiao, Q., Jousilahti, P., Antikainen, R., Tuomilehto, J.·2006·Diabetologia
DOI 10.1007/s00125-006-0435-9
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Abstract

Aims/hypothesis Higher habitual coffee drinking has been associated with a lower risk of developing type 2 diabetes. The relation between coffee consumption and risk of cardiovascular disease (CVD) has been examined in many studies, but the issue remains controversial. This study was designed to assess the association between coffee consumption and CVD mortality among patients with type 2 diabetes.Methods We prospectively followed 3,837 randomly ascertained Finnish patients with type 2 diabetes aged 25 to 74 years. Coffee consumption and other study parameters were determined at baseline. The International Classification of Diseases was used to identify CHD, CVD and stroke cases using computerised record linkage to the national Death Registry. The associations between coffee consumption at baseline and risk of total, CVD, CHD, and stroke mortality were analysed by using Cox proportional hazards models.Results During the average follow-up of 20.8 years, 1,471 deaths were recorded, of which 909 were coded as CVD, 598 as CHD and 210 as stroke. The respective multivariate-adjusted hazard ratios in participants who drank 0-2, 3-4, 5-6, and > or =7 cups of coffee daily were 1.00, 0.77, 0.68 and 0.70 for total mortality (P<0.001 for trend), 1.00, 0.79, 0.70 and 0.71 for CVD mortality (P=0.006 for trend), 1.00, 0.78, 0.70 and 0.63 for CHD mortality (p=0.01 for trend), and 1.00, 0.77, 0.64 and 0.90 for stroke mortality (p=0.12 for trend).Conclusions/interpretation In this large prospective study we found that in type 2 diabetic patients coffee drinking is associated with reduced total, CVD and CHD mortality.

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  1. World Health Organization Consultation (1999) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. WHO, Geneva

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Metadata

Authors
Bidel, S., Hu, G., Qiao, Q., Jousilahti, P., Antikainen, R., & Tuomilehto, J.
Affiliations
  • University of Helsinki (FI)
  • Tampere University (FI)
Corresponding author
Bidel, S.
ORCID
Venue
Diabetologia
Publisher
Springer Science and Business Media LLC
Published
2006-09-21
Volume
49
Issue
11
Pages
2618-2626
ISSN
  • 0012-186X (ISSN-L)
  • 1432-0428
DOI
10.1007/s00125-006-0435-9
OpenAlex
W2131410623
Cited by
107
References
54
Citations by year
2026: 2 · 2025: 5 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 9 · 2020: 6 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 8 · 2014: 7 · 2013: 11 · 2012: 10
FWCI
4.81
Type
journal article
Language
en
Open access
Licence
www.springer.com/tdm (tdm)
Locations
  • Diabetologia (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Foundation for Cardiovascular Research
  • Academy of Finland (46558, 204274, 205657)
  • Juho Vainion Säätiö
  • Sydäntutkimussäätiö
Topics
  • Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
coffee consumption, type 2 diabetes, cardiovascular mortality, coronary heart disease mortality, stroke mortality, all-cause mortality, cardiovascular disease, mortality risk
MeSH terms
Adult, Cardiovascular Diseases, Coffee, Coronary Disease, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Female, Finland, Humans, Male, Middle Aged, Prospective Studies, Surveys and Questionnaires, Body Mass Index, Risk Assessment

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