Cited by 273Bariatric Surgery and OutcomesMinimally Invasive Surgical TechniquesDiabetes Management and Research

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Nationwide cohort study of post-gastric bypass hypoglycaemia including 5,040 patients undergoing surgery for obesity in 1986–2006 in Sweden

Open access

Marsk, R., Jonas, E., Rasmussen, F., Näslund, E.·2010·Diabetologia

Open this paper in CoChat — free account Open PDF

Abstract

Aims/hypothesis Symptomatic hypoglycaemia with related confusion, syncope, epilepsy or seizures is a newly recognised complication of gastric bypass surgery for obesity. The incidence of these conditions is not known. We therefore studied the incidence of post-gastric bypass hypoglycaemia and related symptoms in patients who have undergone gastric bypass and a reference cohort from the general population of Sweden.Methods This is a nationwide cohort study based on national registries with 5,040 persons who underwent gastric bypass, vertical banded gastroplasty or gastric banding for obesity in Sweden between 1 January 1986 and 31 December 2006 and a cohort of ten referents per patient matched for sex and age randomly sampled from the general population. The incidence rates of hospitalisation for hypoglycaemia, confusion, syncope, epilepsy or seizures before and after dates of surgery or inclusion in the reference cohort were studied.Results Preoperative incidences of hospitalisation for hypoglycaemia were similar in the surgical and referent cohorts. After gastric bypass surgery, the adjusted hazard ratios were significantly elevated for hypoglycaemia (2.7 [95% CI 1.2-6.3]), confusion (2.8 [1.3-6.0]), syncope (4.9 [3.4-7.0]), epilepsy (3.0 [2.1-4.3]) and seizures (7.3 [5.0-10.8]). The proportions of gastric bypass patients and reference participants affected by hypoglycaemia were very low (0.2% and 0.04%, respectively). There was no increased risk of hypoglycaemia after vertical banded gastroplasty or gastric banding compared with the referent population.Conclusions/interpretation Obese persons who have undergone gastric bypass have an increased risk of hospitalisation for diagnoses associated with post-gastric bypass hypoglycaemia, although few patients are affected.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1007/s00125-010-1798-5

Cites

12 of 12 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
Sjöström, L., Lindroos, A.-K., Peltonen, M., Torgerson, J., Bouchard, C., Carlsson, B., Dahlgren, S., Larsson, B., Narbro, K., Sjöström, C. D., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa035622 · Cited by 4,457
Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery.
Service, G. J., Thompson, G. B., Service, F. J., Andrews, J. C., Collazo-Clavell, M. L., & Lloyd, R. V. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043690 · Cited by 779
Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass
le Roux, C. W., Welbourn, R., Werling, M., Osborne, A., Kokkinos, A., Laurenius, A., Lönroth, H., Fändriks, L., Ghatei, M. A., Bloom, S. R., et al. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e3180caa3e3 · Cited by 741 · cited 1×
“One mechanism postulated to improve diabetes after gastric bypass is an augmented incretin response; postprandial plasma concentrations of the potent incretin glucagon-like peptide-1 rise after gastric bypass [2].”
Background
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, J. J., & Patti, M. E. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0918 · Cited by 377
Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia.
Patti, M. E., McMahon, G., Mun, E. C., Bitton, A., Holst, J. J., Goldsmith, J., Hanto, D. W., Callery, M., Arky, R., Nose, V., et al. (2005) · Diabetologia · doi:10.1007/s00125-005-1933-x · Cited by 365
Hyperinsulinemic Hypoglycemia After Gastric Bypass Surgery Is Not Accompanied by Islet Hyperplasia or Increased β-Cell Turnover
Meier, J. J., Butler, A. E., Galasso, R., & Butler, P. C. (2006) · Diabetes Care · doi:10.2337/dc06-0392 · Cited by 249
Postgastric bypass hyperinsulinemic hypoglycemia syndrome: characterization and response to a modified diet.
Kellogg, T., Bantle, J., Leslie, D., Redmond, J., Slusarek, B. M., Swan, T., Buchwald, H., & Ikramuddin, S. (2008) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2008.05.005 · Cited by 215
Dumping Syndrome: Pathophysiology and Treatment
Ukleja, A. (2005) · Nutrition in Clinical Practice · doi:10.1177/0115426505020005517 · Cited by 210
Post−Gastric Bypass Hyperinsulinism With Nesidioblastosis: Subtotal or Total Pancreatectomy May Be Needed to Prevent Recurrent Hypoglycemia
Clancy, T. E., Moore, F. D., & Zinner, M. J. (2006) · Journal of Gastrointestinal Surgery · doi:10.1016/j.gassur.2006.04.008 · Cited by 133
Comment to: Patti ME, Mcmahon G, Mun EC et al. (2005) Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 48:2236–2240
Meier, J. J., Nauck, M. A., & Butler, P. C. (2006) · Diabetologia · doi:10.1007/s00125-005-0114-2 · Cited by 64

Show all 12 references

Sorted by citations

ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes
Jensen, R. T., Cadiot, G., Brandi, M. L., de Herder, W. W., Kaltsas, G., Komminoth, P., Scoazec, J., Salazar, R., Sauvanet, A., & Kianmanesh, R. (2012) · Neuroendocrinology · doi:10.1159/000335591 · Cited by 615
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
Halban, P. A., Polonsky, K. S., Bowden, D. W., Hawkins, M. A., Ling, C., Mather, K. J., Powers, A. C., Rhodes, C. J., Sussel, L., & Weir, G. C. (2014) · Diabetes Care · doi:10.2337/dc14-0396 · Cited by 460
“Although studies to date have not clearly dissected changes in insulin sensitivity from changes in b-cell function, augmentedGLP-1 secretion amplifies RYGB’s antidiabetes effects on pancreatic islets (79), and post-RYGB hyperinsulinemic hypoglycemiamay involve b-cell hypertrophy or neogenesis as well (80,81).”
Background
Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
Graaf, C. D., Donnelly, D., Wootten, D., Lau, J., Sexton, P. M., Miller, L. J., Ahn, J.-M., Liao, J., Fletcher, M. M., Yang, D., et al. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.011395 · Cited by 403
Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides
Falkén, Y., Hellström, P. M., Holst, J. J., & Näslund, E. B. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2876 · Cited by 315
Self-citation
Current treatment paradigms and emerging therapies for NAFLD/NASH
Raza, S. (2020) · Frontiers in bioscience · doi:10.2741/4892 · Cited by 329
Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery
Madsbad, S., Dirksen, C., & Holst, J. J. (2014) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(13)70218-3 · Cited by 307
Dumping syndrome after esophageal, gastric or bariatric surgery: Pathophysiology, diagnosis, and management
van Beek, A. P., Emous, M., Laville, M., & Tack, J. (2017) · Obesity Reviews · doi:10.1111/obr.12467 · Cited by 288
“Patients were also at increased risk for confusion, syncope, epilepsy and seizures after gastric bypass surgery (19).”
Background
Pancreatic neuroendocrine tumors: Clinical features, diagnosis and medical treatment: Advances
Ito, T., Igarashi, H., & Jensen, R. T. (2012) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2012.12.003 · Cited by 254
Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care
Shawe, J., Ceulemans, D., Akhter, Z., Neff, K., Hart, K. H., Heslehurst, N., Štotl, I., Agrawal, S., Steegers‐Theunissen, R. P. M., Taheri, S., et al. (2019) · Obesity Reviews · doi:10.1111/obr.12927 · Cited by 248
Laparoscopic sleeve gastrectomy: More than a restrictive bariatric surgery procedure?
Benaiges, D. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i41.11804 · Cited by 238
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
Halban, P. A., Polonsky, K. S., Bowden, D. W., Hawkins, M. A., Ling, C., Mather, K. J., Powers, A. C., Rhodes, C. J., Sussel, L., & Weir, G. C. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1425 · Cited by 242
Hyperinsulinemic Hypoglycemia after Bariatric Surgery: Diagnosis and Management Experience from a Spanish Multicenter Registry
Vilarrasa, N., Goday, A., Rubio, M. A., Caixàs, A., Pellitero, S., Ciudin, A., Calañas, A., Botella, J. I., Bretón, I., Morales, M. J., et al. (2016) · Obesity Facts · doi:10.1159/000442764 · Cited by 197
Glucose metabolism after bariatric surgery: implications for T2DM remission and hypoglycaemia
Sandoval, D. A., & Patti, M. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00757-5 · Cited by 218
Metabolic Surgery
Pareek, M., Schauer, P. R., Kaplan, L. M., Leiter, L. A., Rubino, F., & Bhatt, D. L. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.12.014 · Cited by 187
Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy: Postsurgical Hypoglycemic Symptoms
Lee, C. J., Clark, J. M., Schweitzer, M., Magnuson, T., Steele, K., Koerner, O., & Brown, T. T. (2015) · Obesity · doi:10.1002/oby.21042 · Cited by 159
“RYGB is strongly correlated with postbariatric surgery hypoglycemic symptoms in our study in conjunction with the findings of prior studies (12,15,16,22).”
BackgroundResult
Diet approach before and after bariatric surgery
Bettini, S., Belligoli, A., Fabris, R., & Busetto, L. (2020) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-020-09571-8 · Cited by 173
Hypoglycemia after Roux-En-Y gastric bypass: detection rates of continuous glucose monitoring (CGM) versus mixed meal test
Kefurt, R., Langer, F. B., Schindler, K., Shakeri‐Leidenmühler, S., Ludvik, B. H., & Prager, G. (2014) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2014.11.003 · Cited by 151
Bariatric Surgery for Obesity
le Roux, C. W., & Heneghan, H. M. (2018) · Medical Clinics of North America · doi:10.1016/j.mcna.2017.08.011 · Cited by 139
Prevalence of Self-reported Symptoms After Gastric Bypass Surgery for Obesity
Gribsholt, S. B., Pedersen, A. M., Svensson, E., Thomsen, R. W., & Richelsen, B. (2016) · JAMA Surgery · doi:10.1001/jamasurg.2015.5110 · Cited by 132
ASMBS Position Statement on Postprandial Hyperinsulinemic Hypoglycemia after Bariatric Surgery
Eisenberg, D., Azagury, D. E., Ghiassi, S., Grover, B. T., & Kim, J. J. (2016) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.12.005 · Cited by 130
Incidence of Hypoglycemia After Gastric Bypass vs Sleeve Gastrectomy: A Randomized Trial
Capristo, E., Panunzi, S., Gaetano, A. D., Spuntarelli, V., Bellantone, R. D. A., Giustacchini, P., Birkenfeld, A. L., Amiel, S. A., Bornstein, S. R., Raffaelli, M., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01695 · Cited by 127
Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia
Craig, C. M., Liu, L.-F., Deacon, C. F., Holst, J. J., & McLaughlin, T. (2016) · Diabetologia · doi:10.1007/s00125-016-4179-x · Cited by 121
Clinical features and morphological characterization of 10 patients with noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS)
Won, J. G. S., Tseng, H., Yang, A., Tang, K., Jap, T., Lee, C. H., Lin, H., Burcus, N. I., Pittenger, G. L., & Vinik, A. I. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02629.x · Cited by 108
MANAGEMENT OF ENDOCRINE DISEASE: Pathogenesis and management of hypoglycemia
Kittah, N. E., & Vella, A. (2017) · European Journal of Endocrinology · doi:10.1530/eje-16-1062 · Cited by 107
Prevention and treatment of nutritional complications after bariatric surgery
Nuzzo, A., Czernichow, S., Hertig, A., Ledoux, S., Poghosyan, T., Quilliot, D., Gall, M. L., Bado, A., & Joly, F. (2021) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(20)30331-9 · Cited by 115
Laparoscopic reversal of Roux-en-Y gastric bypass: Technique and utility for treatment of endocrine complications
Campos, G. M., Ziemelis, M., Paparodis, R., Ahmed, M., & Belt Davis, D. (2014) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2013.05.012 · Cited by 104
GLP1 analogs as treatment of postprandial hypoglycemia following gastric bypass surgery: A potential new indication?
Abrahamsson, N., Engström, B. E., Sundbom, M., & Karlsson, F. A. (2013) · European Journal of Endocrinology · doi:10.1530/eje-13-0504 · Cited by 99
Acarbose Improves Hypoglycaemia Following Gastric Bypass Surgery Without Increasing Glucagon-Like Peptide 1 Levels
Valderas, J. P., Ahuad, J., Rubio, L., Escalona, M., Pollak, F., & Maiz, A. (2012) · Obesity Surgery · doi:10.1007/s11695-011-0581-0 · Cited by 97
The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control
Douros, J. D., Tong, J., & D’Alessio, D. A. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00183 · Cited by 100
Prevalence, severity, and predictors of symptoms of dumping and hypoglycemia after Roux-en-Y gastric bypass.
Nielsen, J., Pedersen, A. M., Gribsholt, S. B., Svensson, E., & Richelsen, B. (2016) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.04.017 · Cited by 82
Continuous Glucose Monitoring for Evaluation of Glycemic Excursions after Gastric Bypass
Halperin, F., Patti, M., Skow, M., Bajwa, M. A., & Goldfine, A. B. (2011) · Journal of Obesity · doi:10.1155/2011/869536 · Cited by 91
Recognition and management of hyperinsulinemic hypoglycemia after bariatric surgery
Malik, S., Mitchell, J. E., Steffen, K. J., Engel, S. G., Wiisanen, R., Garcia, L., & Malik, S. A. (2015) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2015.07.003 · Cited by 88
Laparoscopic reversal of Roux-en-Y gastric bypass into normal anatomy with or without sleeve gastrectomy
Vilallonga, R., van de Vrande, S., & Himpens, J. (2013) · Surgical Endoscopy · doi:10.1007/s00464-013-3087-0 · Cited by 85
Dumping Syndrome Following Gastric Bypass: Validation of the Dumping Symptom Rating Scale
Laurenius, A., Olbers, T., Näslund, I., & Karlsson, J. (2013) · Obesity Surgery · doi:10.1007/s11695-012-0856-0 · Cited by 83
Hypoglycemia after Roux-en-Y Gastric Bypass: The BOLD Experience
Sarwar, H., Chapman, W. H. H., Pender, J. R., Ivanescu, A. E., Drake, A. J., Pories, W. J., & Dar, M. S. (2014) · Obesity Surgery · doi:10.1007/s11695-014-1260-8 · Cited by 83
The short- to mid-term symptom prevalence of dumping syndrome after primary gastric-bypass surgery and its impact on health-related quality of life.
Emous, M., Wolffenbuttel, B., Totté, E., & van Beek, A. V. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2017.04.028 · Cited by 71
Insulin Sensitivity and Secretion Changes After Gastric Bypass in Normotolerant and Diabetic Obese Subjects
Salinari, S., BERTUZZI, A., Guidone, C., Previti, E., Rubino, F., & Mingrone, G. (2012) · Annals of Surgery · doi:10.1097/sla.0b013e318269cf5c · Cited by 74
Risk of Post-Gastric Bypass Surgery Hypoglycemia in Nondiabetic Individuals: A Single Center Experience
Lee, C. J., Wood, G., Lazo, M., Brown, T. T., Clark, J. M., Still, C., & Benotti, P. (2016) · Obesity · doi:10.1002/oby.21479 · Cited by 67
Do Gut Hormones Contribute to Weight Loss and Glycaemic Outcomes after Bariatric Surgery?
Papamargaritis, D., & le Roux, C. W. (2021) · Nutrients · doi:10.3390/nu13030762 · Cited by 68
Hypoglycemia After Gastric Bypass: The Dark Side of GLP-1
Patti, M., & Goldfine, A. B. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.01.038 · Cited by 69
Advances in the Etiology and Management of Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass
Cui, Y., Elahi, D., & Andersen, D. K. (2011) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-011-1585-8 · Cited by 66
Hormonal Response to a Mixed-Meal Challenge After Reversal of Gastric Bypass for Hypoglycemia
Lee, C. J., Brown, T., Magnuson, T. H., Egan, J. M., Carlson, O., & Elahi, D. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1151 · Cited by 65
Incidence and Predictive Factors of Postprandial Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass
Raverdy, V., Baud, G., Pigeyre, M., Verkindt, H., Torres, F., Preda, C., Thuillier, D., Gelé, P., Vantyghem, M., Caiazzo, R. J., et al. (2016) · Annals of Surgery · doi:10.1097/sla.0000000000001915 · Cited by 69
Can medical therapy mimic the clinical efficacy or physiological effects of bariatric surgery?
Miras, A. D., & le Roux, C. W. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.205 · Cited by 65
Weight regain in patients with symptoms of post–bariatric surgery hypoglycemia
Varma, S., Clark, J. M., Schweitzer, M., Magnuson, T. H., Brown, T. T., & Lee, C. J. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2017.06.004 · Cited by 67
Hypoglycemia in everyday life after gastric bypass and duodenal switch
Abrahamsson, N., Engström, B. E., Sundbom, M., & Karlsson, F. A. (2015) · European Journal of Endocrinology · doi:10.1530/eje-14-0821 · Cited by 66
Recent Developments in Therapeutic Peptides for the Glucagon-like Peptide 1 and 2 Receptors
Suzuki, R., Brown, G. A., Christopher, J. A., Scully, C. C. G., & Congreve, M. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b00835 · Cited by 64
Insulin response to oral stimuli and glucose effectiveness increased in neuroglycopenia following gastric bypass
Patti, M., Li, P., & Goldfine, A. B. (2015) · Obesity · doi:10.1002/oby.21043 · Cited by 63
Postprandial hyperinsulinemic hypoglycemia after gastric bypass surgical treatment
Mala, T. (2014) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2014.01.010 · Cited by 75
Endocrine and Metabolic Complications After Bariatric Surgery
Jammah, A. A. (2015) · Saudi Journal of Gastroenterology · doi:10.4103/1319-3767.164183 · Cited by 67
Roles of increased glycaemic variability, GLP-1 and glucagon in hypoglycaemia after Roux-en-Y gastric bypass
Tharakan, G., Behary, P., Albrechtsen, N. J. W., Chahal, H., Kenkre, J. S., Miras, A. D., Ahmed, A. R., Holst, J. J., Bloom, S. R., & Tan, T. (2017) · European Journal of Endocrinology · doi:10.1530/eje-17-0446 · Cited by 65
Roux en Y gastric bypass hypoglycemia resolves with gastric feeding or reversal: Confirming a non-pancreatic etiology
Davis, D. B., Khoraki, J., Ziemelis, M., Sirinvaravong, S., Han, J. Y., & Campos, G. M. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2017.12.011 · Cited by 63
European guideline on obesity care in patients with gastrointestinal and liver diseases – Joint ESPEN/UEG guideline
Bischoff, S. C., Barazzoni, R., Busetto, L., Campmans-Kuijpers, M. J. E., Cardinale, V., Chermesh, I., Eshraghian, A., Kani, H. T., Khannoussi, W., Lacaze, L., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.07.003 · Cited by 70
Hypoglycemia complicating bariatric surgery: incidence and mechanisms
Foster-Schubert, K. (2011) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/med.0b013e32834449b9 · Cited by 64
Post-bypass hypoglycaemia: A review of current findings
Ritz, P., & Hanaire, H. (2011) · Diabetes & Metabolism · doi:10.1016/j.diabet.2011.04.003 · Cited by 56
Metabolic Surgery for Hypertension in Patients With Obesity
Pareek, M., Bhatt, D. L., Schiavon, C. A., & Schauer, P. R. (2019) · Circulation Research · doi:10.1161/circresaha.118.313320 · Cited by 61
European guideline on obesity care in patients with gastrointestinal and liver diseases – Joint European Society for Clinical Nutrition and Metabolism / United European Gastroenterology guideline
Bischoff, S. C., Barazzoni, R., Busetto, L., Campmans-Kuijpers, M. J. E., Cardinale, V., Chermesh, I., Eshraghian, A., Kani, H. T., Khannoussi, W., Lacaze, L., et al. (2022) · United European Gastroenterology Journal · doi:10.1002/ueg2.12280 · Cited by 62
Diagnostic tools for post‐gastric bypass hypoglycaemia
Emous, M., Ubels, F. L., & van Beek, A. P. (2015) · Obesity Reviews · doi:10.1111/obr.12307 · Cited by 58
Endoluminal Revision (OverStitch TM , Apollo Endosurgery) of the Dilated Gastroenterostomy in Patients with Late Dumping Syndrome After Proximal Roux-en-Y Gastric Bypass
Stier, C. K., & Chiappetta, S. (2016) · Obesity Surgery · doi:10.1007/s11695-016-2266-1 · Cited by 51
Rate of Acute Hospital Admissions Before and After Roux-en-Y Gastric Bypass Surgery
Gribsholt, S. B., Svensson, E., Richelsen, B., Raundahl, U., Sørensen, H. T., & Thomsen, R. W. (2016) · Annals of Surgery · doi:10.1097/sla.0000000000002113 · Cited by 50
The incidence and risk factors associated with developing symptoms of hypoglycemia after bariatric surgery
Lee, C. J., Brown, T. T., Schweitzer, M., Magnuson, T., & Clark, J. M. (2018) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2018.01.028 · Cited by 49
Overall and cause-specific mortality after Roux-en-Y gastric bypass surgery: A nationwide cohort study
Gribsholt, S. B., Thomsen, R. W., Svensson, E., & Richelsen, B. (2016) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.10.007 · Cited by 49
Bariatric surgery and diabetes remission: Who would have thought it?
Singh, A., Singh, R., & Kota, S. (2015) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.163113 · Cited by 48
Remission of Type 2 Diabetes After Roux-en-Y Gastric Bypass or Sleeve Gastrectomy Is Associated With a Distinct Glycemic Profile
Jiménez, A., Ceriello, A., Casamitjana, R., Flores, L., Viaplana-Masclans, J., & Vidal, J. (2014) · Annals of Surgery · doi:10.1097/sla.0000000000000586 · Cited by 48
Effect of Carbohydrate Restriction in Patients with Hyperinsulinemic Hypoglycemia after Roux-en-Y Gastric Bypass
Botros, N., Rijnaarts, I., Brandts, H., Bleumink, G., Janssen, I., & de Boer, H. D. (2014) · Obesity Surgery · doi:10.1007/s11695-014-1319-6 · Cited by 45
Hyperinsulinaemic Hypoglycaemia
Arya, V., Mohammed, Z., Blankenstein, O., de Lonlay, P., & Hussain, K. (2014) · Hormone and Metabolic Research · doi:10.1055/s-0034-1367063 · Cited by 18
Hypoglycaemia following gastric bypass surgery—diabetes remission in the extreme?
Patti, M., & Goldfine, A. B. (2010) · Diabetologia · doi:10.1007/s00125-010-1884-8 · Cited by 45
Effect of meal size and texture on gastric pouch emptying and glucagon-like peptide 1 after gastric bypass surgery
Stano, S., Alam, F., Wu, L., Dutia, R., Ng, S.-N., Sala, M., McGinty, J., & Laferrère, B. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2017.09.004 · Cited by 46
A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis
Ganguli, S., Deleeuw, P., & Satapathy, S. K. (2019) · Hepatic Medicine Evidence and Research · doi:10.2147/hmer.s188991 · Cited by 48
Practical guideline on obesity care in patients with gastrointestinal and liver diseases – Joint ESPEN/UEG guideline
Bischoff, S. C., Ockenga, J., Eshraghian, A., Barazzoni, R., Busetto, L., Campmans-Kuijpers, M. J. E., Cardinale, V., Chermesh, I., Kani, H. T., Khannoussi, W., et al. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.03.021 · Cited by 47
Loop Duodenojejunal Bypass with Sleeve Gastrectomy: Comparative Study with Roux-en-Y Gastric Bypass in Type 2 Diabetic Patients with a BMI <35 kg/m2, First Year Results
Huang, C., Tai, C., Chang, P., Malapan, K., Tsai, C., & Yolsuriyanwong, K. (2016) · Obesity Surgery · doi:10.1007/s11695-016-2118-z · Cited by 44
Increased risk of OGTT-induced hypoglycemia after gastric bypass in severely obese patients with normal glucose tolerance
Pigeyre, M., Vaurs, C., Raverdy, V., Hanaire, H. P., Ritz, P., & Pattou, F. N. (2014) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2014.12.004 · Cited by 42
Surgery in the treatment of type 2 diabetes mellitus
Maleckas, A., Venclauskas, L., Wallenius, V., Lönroth, H., & Fändriks, L. (2015) · Scandinavian Journal of Surgery · doi:10.1177/1457496914561140 · Cited by 43
Hypoglycaemia after gastric bypass: mechanisms and treatment
Ritz, P., Vaurs, C., Barigou, M., & Hanaire, H. P. (2015) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12592 · Cited by 42
Rate of post-bariatric hypoglycemia using continuous glucose monitoring: A meta-analysis of literature studies
Lupoli, R., Lembo, E., Rainone, C., Schiavo, L., Iannelli, A., Minno, M. N. D. D., & Capaldo, B. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.08.047 · Cited by 42
Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
Sheehan, A., & Patti, M. E. (2020) · Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy · doi:10.2147/dmso.s233078 · Cited by 39
Postprandial hyperinsulinemic hypoglycemia after Roux-en-Y gastric bypass: an update
Øhrstrøm, C. C., Worm, D., & Hansen, D. L. (2016) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.09.025 · Cited by 40
Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia
Hazlehurst, J., Khoo, B. C. E., Lobato, C. B., Ilesanmi, I., Abbott, S., Chan, T. L., Pillai, S., Maslin, K., Purkayastha, S., McGowan, B. M., et al. (2024) · Endocrine Connections · doi:10.1530/ec-23-0285 · Cited by 43
Metabolic surgery: shifting the focus from glycaemia and weight to end-organ health
Miras, A. D., & le Roux, C. W. (2014) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(13)70158-x · Cited by 37
Gastroparesis and Dumping Syndrome: Current Concepts and Management
Vavricka, S. R., & Greuter, T. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081127 · Cited by 39
Impact of Postprandial Hypoglycemia on Weight Loss After Bariatric Surgery
Rebelos, E., Moriconi, D., Scalese, M., Denoth, F., Molinaro, S., Siciliano, V., Anselmino, M., Taddei, S., Ferrannini, E., & Nannipieri, M. (2020) · Obesity Surgery · doi:10.1007/s11695-020-04465-9 · Cited by 35
Canagliflozin: A New Therapeutic Option in Patients That Present Postprandial Hyperinsulinemic Hypoglycemia after Roux-en-Y Gastric Bypass: A Pilot Study
Ciudin, A., Sanchez, M. J. B., Hernández, I., Cordero-Vázquez, E., Fidilio, E., Comas, M., Gonzalez, C., Lopez, N., Vilallonga, R., Giralt, M., et al. (2021) · Obesity Facts · doi:10.1159/000515598 · Cited by 39
Glucagon‐Like Peptide‐1: Actions and Influence on Pancreatic Hormone Function
Davis, E., & Sandoval, D. A. (2020) · Comprehensive physiology · doi:10.1002/cphy.c190025 · Cited by 53
Postbariatric hypoglycemia: symptom patterns and associated risk factors in the Longitudinal Assessment of Bariatric Surgery study
Fischer, L. E., Wolfe, B. M., Fino, N., Elman, M. R., Flum, D. R., Mitchell, J. E., Pomp, A., Pories, W. J., Purnell, J. Q., Patti, M.-E., et al. (2021) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2021.04.021 · Cited by 36
Insulin-Like Growth Factor 1 Predicts Post-Load Hypoglycemia following Bariatric Surgery: A Prospective Cohort Study
Itariu, B. K., Zeyda, M., Prager, G., & Stulnig, T. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094613 · Cited by 38
Post‐gastric bypass hypoglycaemia: a review
Shantavasinkul, P. C., Torquati, A., & Corsino, L. (2016) · Clinical Endocrinology · doi:10.1111/cen.13033 · Cited by 36
Hypoglycemia Following Bariatric Surgery: Our 31-Year Experience
Michaels, A. D., Mehaffey, J. H., French, W. B., Schirmer, B. D., Kirby, J. L., & Hallowell, P. T. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2734-2 · Cited by 34
Mechanisms of action of a carbohydrate-reduced, high-protein diet in reducing the risk of postprandial hypoglycemia after Roux-en-Y gastric bypass surgery
Kandel, D., Bojsen-Møller, K. N., Svane, M. S., Samkani, A., Astrup, A. V., Holst, J. J., Madsbad, S., & Krarup, T. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy310 · Cited by 35
Frequency of Hypoglycaemia after Different Bariatric Surgical Procedures
Brix, J. M., Kopp, H.-P., Höllerl, F., Schernthaner, G.-H., Ludvik, B. H., & Schernthaner, G. (2019) · Obesity Facts · doi:10.1159/000493735 · Cited by 34
Treatment of severe postRYGB hyperinsulinemic hypoglycemia with pasireotide: A comparison with octreotide on insulin, glucagon, and GLP-1
de Heide, L. J. M., Laskewitz, A. J., & Apers, J. A. (2014) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2013.11.006 · Cited by 33
Postbariatric surgery hypoglycemia: Nutritional, pharmacological and surgical perspectives
Rossini, G., Risi, R., Monte, L., Sancetta, B. M., Quadrini, M., Ugoccioni, M., Masi, D., Rossetti, R., D’Alessio, R., Mazzilli, R., et al. (2023) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3750 · Cited by 35
Effect of single anastomosis duodenal-ileal bypass with sleeve gastrectomy on glucose tolerance test: comparison with other bariatric procedures.
Sessa, L., Guidone, C., Gallucci, P., Capristo, E., Mingrone, G., & Raffaelli, M. (2019) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2019.04.013 · Cited by 28
Hypoglycemia after gastric bypass surgery
Singh, E., & Vella, A. (2012) · Diabetes Spectrum · doi:10.2337/diaspect.25.4.217 · Cited by 30
The Impact of Bariatric Surgery on Type 2 Diabetes Mellitus and the Management of Hypoglycemic Events
Kassem, M. A. M., Durda, M. A., Stoicea, N., Cavus, O., Sahin, L., & Rogers, B. M. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00037 · Cited by 31
Common and Rare Complications of Bariatric Surgery
Collazo–Clavell, M. L., & Shah, M. (2020) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2020.02.003 · Cited by 31
Post-prandial hypoglycemia results from a non-glucose-dependent inappropriate insulin secretion in Roux-en-Y gastric bypassed patients
Vaurs, C., Brun, J. ‐., Bertrand, M., Burcelin, R., du Rieu, M. C., Anduze, Y., Hanaire, H. P., & Ritz, P. (2015) · Metabolism · doi:10.1016/j.metabol.2015.10.020 · Cited by 32
The big fat bariatric bandwagon
Pinkney, J. H., Johnson, A. B., & Gale, E. A. M. (2010) · Diabetologia · doi:10.1007/s00125-010-1845-2 · Cited by 29
Evaluation of carbohydrate restriction as primary treatment for post-gastric bypass hypoglycemia.
van Meijeren, J., Timmer, I., Brandts, H., Janssen, I., & de Boer, H. D. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.11.004 · Cited by 27
Postprandial hypoglycaemia after Roux-en-Y gastric bypass in individuals with type 2 diabetes
Guarino, D., Moriconi, D., Mari, A., Rebelos, E., Colligiani, D., Baldi, S., Anselmino, M., Ferrannini, E., & Nannipieri, M. (2018) · Diabetologia · doi:10.1007/s00125-018-4737-5 · Cited by 30
ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?
Nichols, C. G., York, N., & Remedi, M. S. (2022) · Diabetes · doi:10.2337/db21-0755 · Cited by 31

Authors: Marsk, R., Jonas, E., Rasmussen, F., & Näslund, E.
Affiliations: Danderyds sjukhus (SE)
Karolinska Institutet (SE)
Corresponding author: Näslund, E.
ORCID: Marsk, R.
Jonas, E.
Rasmussen, F.
Näslund, E.
Venue: Diabetologia
Publisher: Springer Science and Business Media LLC
Published: 2010-05-22
Volume: 53
Issue: 11
Pages: 2307-2311
ISSN: 0012-186X (ISSN-L)
1432-0428
DOI: 10.1007/s00125-010-1798-5
OpenAlex: W2036282220
Cited by: 273
References: 12
Citations by year: 2026: 8 · 2025: 7 · 2024: 10 · 2023: 18 · 2022: 22 · 2021: 18 · 2020: 21 · 2019: 18 · 2018: 20 · 2017: 15 · 2016: 31 · 2015: 20 · 2014: 21 · 2013: 15 · 2012: 12
FWCI: 14.49
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Diabetologia (publishedVersion)
PubMed (publishedVersion)
Funders: Karolinska Institutet
Stockholms Läns Landsting
Vetenskapsrådet
Topics: Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords: bariatric surgery, gastric bypass, confusion, syncope, epilepsy, seizures, hospitalization, vertical banded gastroplasty, gastric banding, incidence
MeSH terms: Adult, Confusion, Epilepsy, Female, Humans, Hypoglycemia, Male, Middle Aged, Obesity, Postoperative Complications, Seizures, Syncope, Cohort Studies, Gastric Bypass, Gastroplasty

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nationwide cohort study of post-gastric bypass hypoglycaemia including 5,040 patients undergoing surgery for obesity in 1986–2006 in Sweden

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks