MANAGEMENT OF ENDOCRINE DISEASE: Pathogenesis and management of hypoglycemia
Abstract
Glucose is the main substrate utilized by the brain and as such multiple regulatory mechanisms exist to maintain glucose concentrations. When these mechanisms fail or are defective, hypoglycemia ensues. Due to these robust mechanisms, hypoglycemia is uncommon and usually occurs in the setting of the treatment of diabetes using glucose-lowering agents such as sulfonylureas or insulin. The symptoms of hypoglycemia are non-specific and as such it is important to confirm hypoglycemia by establishing the presence of Whipple's triad before embarking on an evaluation for hypoglycemia. When possible, evaluation of hypoglycemia should be carried out at the time of spontaneous occurrence of symptoms. If this is not possible then one would want to create the circumstances under which symptoms occur. In cases where symptoms occur in the post absorptive state, a 72-h fast should be performed. Likewise, if symptoms occur after a meal then a mixed meal study may be the test of choice. The causes of endogenous hyperinsulinemic hypoglycemia include insulinoma, post-bariatric hypoglycemia and noninsulinoma pancreatogenous hypoglycemia syndrome. Autoimmune hypoglycemia syndrome is clinically and biochemically similar to insulinoma but associated with high levels of insulin antibodies and plasma insulin. Other important causes of hypoglycemia include medications, non-islet cell tumors, hormonal deficiencies, critical illness and factitious hypoglycemia. We provide an overview of the pathogenesis…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Apart from severe diseases like liver, kidney or heart failure, the intake of alcohol, insulin, or insulin secretagogues needs to be ruled out.
“Apart from severe diseases like liver, kidney or heart failure, the intake of alcohol, insulin, or insulin secretagogues needs to be ruled out [7,9,10].”
Cites
Pories, W. J., Swanson, M. S., MacDonald, K. G., Long, S. B., Morris, P. G., Brown, B. M., Barakat, H. A., deRamon, R. A., Israel, G., Dolezal, J. M., et al. (1995) · Annals of Surgery · doi:10.1097/00000658-199509000-00011 · Cited by 2,293 · see citing works
Cryer, P. E., Axelrod, L., Grossman, A. B., Heller, S. R., Montori, V. M., Seaquist, E. R., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1410 · Cited by 1,277 · see citing works
Functioning insulinoma—incidence, recurrence, and long-term survival of patients: a 60-year study.
SERVICE, F. J., McMAHON, M. M., O'BRIEN, P. C., & BALLARD, D. J. (1991) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)62083-7 · Cited by 883 · see citing works
Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery.
Service, G. J., Thompson, G. B., Service, F. J., Andrews, J. C., Collazo-Clavell, M. L., & Lloyd, R. V. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043690 · Cited by 779 · see citing works
Severe hypoglycemia in critically ill patients: risk factors and outcomes
Krinsley, J. S., & Grover, A. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000282073.98414.4b · Cited by 671 · see citing works
Mitrakou, A., Ryan, C., Veneman, T., Mokan, M., Jenssen, T., Kiss, I., Durrant, J., Cryer, P., & Gerich, J. (1991) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1991.260.1.e67 · Cited by 558 · see citing works
Alterations in carbohydrate metabolism during stress: A review of the literature
Mizock, B. A. (1995) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)80083-7 · Cited by 529 · see citing works
Service, F. J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199504273321707 · Cited by 503 · see citing works
CARCINOMA OF THE ISLANDS OF THE PANCREAS
Wilder, R. M., Allan, F. N., Power, M. H., & ROBERTSON, H. E. (1927) · JAMA · doi:10.1001/jama.1927.02690050014007 · Cited by 442 · see citing works
Diverse causes of hypoglycemia-associated autonomic failure in diabetes.
Cryer, P. E. (2004) · New England Journal of Medicine · doi:10.1056/nejmra031354 · Cited by 411 · see citing works
Schwartz, N. S., Clutter, W. E., Shah, S. D., & Cryer, P. E. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112884 · Cited by 394 · see citing works
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, J. J., & Patti, M. E. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0918 · Cited by 377 · see citing works
Patti, M. E., McMahon, G., Mun, E. C., Bitton, A., Holst, J. J., Goldsmith, J., Hanto, D. W., Callery, M., Arky, R., Nose, V., et al. (2005) · Diabetologia · doi:10.1007/s00125-005-1933-x · Cited by 365 · see citing works
BATTERED BABIES—HOW MANY DO WE MISS?
Gans, B. (1970) · The Lancet · doi:10.1016/s0140-6736(70)91756-3 · Cited by 363 · see citing works
Hypoglycemia, functional brain failure, and brain death.
Cryer, P. E. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31669 · Cited by 363 · see citing works
Placzkowski, K. A., Vella, A., Thompson, G. B., Grant, C. S., Reading, C. C., Charboneau, J. W., Andrews, J. C., Lloyd, R. V., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2031 · Cited by 360 · see citing works
Self-citationPredisposing Factors for Adrenal Insufficiency
Bornstein, S. R. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804635 · Cited by 356 · see citing works
Daughaday, W. H., Emanuele, M. A., Brooks, M. H., Barbato, A. L., Kapadia, M., & Rotwein, P. S. (1988) · New England Journal of Medicine · doi:10.1056/nejm198812013192202 · Cited by 348 · see citing works
Hypoglycemia in Hospitalized Patients
Fischer, K. F., Lees, J. A., & Newman, J. H. (1986) · New England Journal of Medicine · doi:10.1056/nejm198611133152002 · Cited by 309 · see citing works
Blockade of Glucagon-like Peptide 1 Receptor Corrects Postprandial Hypoglycemia After Gastric Bypass
Salehi, M., Gastaldelli, A., & D'Alessio, D. A. (2014) · Gastroenterology · doi:10.1053/j.gastro.2013.11.044 · Cited by 289 · see citing works
Grant, C. S. (2005) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2005.05.008 · Cited by 282 · see citing works
Marsk, R., Jonas, E., Rasmussen, F., & Näslund, E. (2010) · Diabetologia · doi:10.1007/s00125-010-1798-5 · Cited by 273 · see citing works
Glucose counterregulation, hypoglycemia, and intensive insulin therapy in diabetes mellitus
Epstein, F. H., Cryer, P. E., & Gerich, J. E. (1985) · New England Journal of Medicine · doi:10.1056/nejm198507253130405 · Cited by 273 · see citing works
Drug-Induced Hypoglycemia: A Review of 1418 Cases
Seltzer, H. S. (1989) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30395-5 · Cited by 266 · see citing works
Towler, D. A., Havlin, C. E., Craft, S., & Cryer, P. (1993) · Diabetes · doi:10.2337/diab.42.12.1791 · Cited by 258 · see citing works
Forty-Eight-Hour Fast: The Diagnostic Test for Insulinoma
Hirshberg, B., Livi, A., Bartlett, D. L., Libutti, S. K., Alexander, H. R., Doppman, J. L., Skarulis, M. C., & Gorden, P. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.9.6807 · Cited by 256 · see citing works
Extensive expertise in endocrinology: adrenal crisis
Allolio, B. (2015) · European Journal of Endocrinology · doi:10.1530/eje-14-0824 · Cited by 251 · see citing works
Meier, J. J., Butler, A. E., Galasso, R., & Butler, P. C. (2006) · Diabetes Care · doi:10.2337/dc06-0392 · Cited by 249 · see citing works
Hypoglycemia is associated with intensive care unit mortality*
Hermanides, J., Bosman, R. J., Vriesendorp, T. M., Dotsch, R., Rosendaal, F. R., Zandstra, D. F., Hoekstra, J. B. L., & DeVries, J. H. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181de562c · Cited by 236 · see citing works
Eighty‐six cases of Addison's disease
Kong, M., & Jeffcoate, W. J. (1994) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1994.tb02790.x · Cited by 224 · see citing works
Drug-Induced Hypoglycemia: A Systematic Review
Murad, M. H., Coto-Yglesias, F., Wang, A. T., Sheidaee, N., Mullan, R. J., Elamin, M. B., Erwin, P. J., & Montori, V. M. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1416 · Cited by 222 · see citing works
Adrenal Hemorrhage: A 25-Year Experience at the Mayo Clinic
Vella, A. V., Nippoldt, T. B., & Morris, J. C. (2001) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)63123-6 · Cited by 219 · see citing works
Self-citationImaging and localization of islet-cell tumours of the pancreas on CT and MRI.
Noone, T. C., Hosey, J., Firat, Z., & Semelka, R. C. (2005) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2004.11.013 · Cited by 217 · see citing works
Kellogg, T., Bantle, J., Leslie, D., Redmond, J., Slusarek, B. M., Swan, T., Buchwald, H., & Ikramuddin, S. (2008) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2008.05.005 · Cited by 215 · see citing works
Hildreth, A. N., Mejia, V. A., Maxwell, R. A., Smith, P. W., Dart, B. W., & Barker, D. E. (2008) · Journal of Trauma: Injury, Infection & Critical Care · doi:10.1097/ta.0b013e31818255e8 · Cited by 197 · see citing works
Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia.
Fukuda, I., Hizuka, N., Ishikawa, Y., Yasumoto, K., Murakami, Y., Sata, A., Morita, J., Kurimoto, M., Okubo, Y., & Takano, K. (2006) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2006.05.003 · Cited by 186 · see citing works
McLaughlin, T., Peck, M., Holst, J., & Deacon, C. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1628 · Cited by 183 · see citing works
Drug-induced Hypoglycemia: A Review Based on 473 Cases
Seltzer, H. S. (1972) · Diabetes · doi:10.2337/diab.21.9.955 · Cited by 181 · see citing works
Christiansen, J. J., Djurhuus, C. B., Gravholt, C. H., Iversen, P., Christiansen, J. S., Schmitz, O., Weeke, J., Jørgensen, J. O. L., & Møller, N. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0445 · Cited by 176 · see citing works
The approach to the adult with newly diagnosed adrenal insufficiency
Arlt, W. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0032 · Cited by 165 · see citing works
Service, F. J. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.5.1582 · Cited by 163 · see citing works
MANAGEMENT OF ENDOCRINE DISEASE: A clinical update on tumor-induced hypoglycemia
Iglesias, P., & Díez, J. J. (2014) · European Journal of Endocrinology · doi:10.1530/eje-13-1012 · Cited by 158 · see citing works
Kauhanen, S. P., Seppänen, M., Minn, H. R. I., Gullichsen, R., Salonen, A., Alanen, K. A., Parkkola, R. K., Solin, O. H., Bergman, J. R., Sane, T., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1479 · Cited by 150 · see citing works
The Diagnosis of Postprandial Hypoglycemia
Lev-Ran, A., & Anderson, R. W. (1981) · Diabetes · doi:10.2337/diab.30.12.996 · Cited by 148 · see citing works
Daughaday, W. H., & Kapadia, M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.17.6778 · Cited by 138 · see citing works
Shah, M., Law, J. H., Micheletto, F., Sathananthan, M., Man, C. D., Cobelli, C., Rizza, R. A., Camilleri, M., Zinsmeister, A. R., & Vella, A. V. (2013) · Diabetes · doi:10.2337/db13-0954 · Cited by 134 · see citing works
Self-citationUS-guided ethanol ablation of insulinomas: a new treatment option
Levy, M. J., Thompson, G. B., Topazian, M. D., Callstrom, M. R., Grant, C. S., & Vella, A. V. (2011) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2011.09.019 · Cited by 130 · see citing works
Self-citationGoldman, J., Baldwin, D., Rubenstein, A. H., Klink, D. D., Blackard, W. G., Fisher, L. K., Roe, T., & Schnure, J. J. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109374 · Cited by 129 · see citing works
Strong association of insulin autoimmune syndrome with HLA-DR4
Uchigata, Y., Eguchi, Y., Takayama-Hasumi, S., Omon, Y., Hirata, Y., Kuwata, S., Tokunaga, K., Miyamoto, M., & Juji, T. (1992) · The Lancet · doi:10.1016/0140-6736(92)90080-m · Cited by 126 · see citing works
Teale, J. D., & Marks, V. (1990) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1990.tb00469.x · Cited by 126 · see citing works
Baxter, R. C., Holman, S., Corbould, A., Stranks, S. N., Ho, P. J., & Braund, W. J. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.9.7545698 · Cited by 126 · see citing works
DeRosa, M. A., & Cryer, P. E. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00539.2003 · Cited by 126 · see citing works
Noninsulinoma pancreatogenous hypoglycemia syndrome: An update in 10 surgically treated patients
Thompson, G. B., Service, F. J., Andrews, J. C., Lloyd, R. V., Natt, N., van Heerden, J. A., & Grant, C. S. (2000) · Surgery · doi:10.1067/msy.2000.110243 · Cited by 121 · see citing works
Jiménez, A., Casamitjana, R., Viaplana-Masclans, J., Lacy, A. M., & Vidal, J. (2013) · Diabetes Care · doi:10.2337/dc12-1535 · Cited by 119 · see citing works
Insulin autoimmune syndrome (IAS, Hirata disease).
Uchigata, Y., & Hirata, Y. (1999) · PubMed · Cited by 109 · see citing works
GRUNBERGER, G., WEINER, J. L., SILVERMAN, R., TAYLOR, S., & GORDEN, P. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-2-252 · Cited by 105 · see citing works
Campos, G. M., Ziemelis, M., Paparodis, R., Ahmed, M., & Belt Davis, D. (2014) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2013.05.012 · Cited by 104 · see citing works
Diagnostic approach to adults with hypoglycemic disorders.
Service, F. (1999) · Endocrinology and metabolism clinics of North America (Print) · doi:10.1016/s0889-8529(05)70086-4 · Cited by 101 · see citing works
Hormonal mechanisms of weight loss and diabetes resolution after bariatric surgery
Cummings, D. E., Overduin, J., Shannon, M. H., & Foster‐Schubert, K. E. (2005) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2005.03.208 · Cited by 98 · see citing works
LUNCHTIME GIN AND TONIC A CAUSE OF REACTIVE HYPOGLYCÆMIA
O’Keefe, S. J., & Marks, V. (1977) · The Lancet · doi:10.1016/s0140-6736(77)91321-6 · Cited by 98 · see citing works
Drug-induced insulin autoimmune syndrome.
Uchigata, Y., Hirata, Y., & Iwamoto, Y. (2009) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2008.10.015 · Cited by 97 · see citing works
Won, J. G., Tseng, H.-S., Yang, A.-H., Tang, K.-T., Jap, T., Lee, C.-H., Lin, H.-D., Burcus, N. I., Pittenger, G., & Vinik, A. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02629.x · Cited by 95 · see citing works
Nuclear medicine in the detection and management of pancreatic islet-cell tumours.
Virgolini, I., Traub-Weidinger, T., & Decristoforo, C. (2005) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2004.09.001 · Cited by 93 · see citing works
Rituximab Selectively Suppresses Specific Islet Antibodies
Yu, L., Herold, K. C., Krause-Steinrauf, H. J., McGee, P. L., Bundy, B. N., Pugliese, A., Krischer, J., Eisenbarth, G. S., & for the Type 1 Diabetes TrialNet Anti-CD20 Study Group (2011) · Diabetes · doi:10.2337/db11-0674 · Cited by 85 · see citing works
Limited Surgery for Benign Tumours of the Pancreas: A Systematic Review
Beger, H. G., Siech, M., Poch, B., Mayer, B., & Schoenberg, M. H. (2015) · World Journal of Surgery · doi:10.1007/s00268-015-2976-x · Cited by 79 · see citing works
Early Endotoxemia Increases Peripheral and Hepatic Insulin Sensitivity in Healthy Humans
van der Crabben, S. N., Blümer, R. M. E., Stegenga, M. E., Ackermans, M. T., Endert, E., Tanck, M. W. T., Serlie, M. J. M., van der Poll, T., & Sauerwein, H. P. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0761 · Cited by 77 · see citing works
Redmon, J., & Nuttall, F. (1999) · Endocrinology and metabolism clinics of North America (Print) · doi:10.1016/s0889-8529(05)70090-6 · Cited by 77 · see citing works
Robot-Assisted Laparoscopic Middle Pancreatectomy
Giulianotti, P. C., Sbrana, F., Bianco, F. M., Addeo, P., & Caravaglios, G. (2010) · Journal of Laparoendoscopic & Advanced Surgical Techniques · doi:10.1089/lap.2009.0296 · Cited by 76 · see citing works
Amano, N., Mukai, T., Ito, Y., Narumi, S., Tanaka, T., Yokoya, S., Ogata, T., & Hasegawa, T. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3525 · Cited by 76 · see citing works
Harness, J. K. (1981) · Archives of Surgery · doi:10.1001/archsurg.1981.01380170055010 · Cited by 73 · see citing works
Pink, D., Schoeler, D., Lindner, T., Thuss-Patience, P. C., Kretzschmar, A., Knipp, H., Vanhoefer, U. J., & Reichardt, P. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.02.4828 · Cited by 70 · see citing works
Hirata, Y., & Ishizu, H. (1972) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.107.277 · Cited by 69 · see citing works
Guettier, J.-M., & Gorden, P. (2006) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2006.09.005 · Cited by 68 · see citing works
Vanderveen, K. A., Grant, C. S., Thompson, G. B., Farley, D. R., Richards, M. L., Vella, A., Vollrath, B., & Service, F. J. (2010) · Surgery · doi:10.1016/j.surg.2010.09.027 · Cited by 67 · see citing works
Self-citationVirally, M., & Guillausseau, P.-J. (1999) · PubMed · Cited by 67 · see citing works
Novel Management of Insulin Autoimmune Syndrome with Rituximab and Continuous Glucose Monitoring
Saxon, D. R., McDermott, M. T., & Michels, A. W. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-1097 · Cited by 67 · see citing works
Insulin autoimmunity and hypoglycemia in seven white patients.
Basu, A., Service, F. J., Yu, L., Heser, D., Ferries, L. M., & Eisenbarth, G. (2005) · Endocrine Practice · doi:10.4158/ep.11.2.97 · Cited by 66 · see citing works
Incretin Hypersecretion in Post-Gastric Bypass Hypoglycemia—Primary Problem or Red Herring?
Vella, A. V., & Service, F. J. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2260 · Cited by 63 · see citing works
Self-citationWhy Does the Gastric Bypass Control Type 2 Diabetes Mellitus?
Pories, W. J. (1992) · Obesity Surgery · doi:10.1381/096089292765559891 · Cited by 63 · see citing works
Tumours producing hypoglycaemia
Marks, V., & Teale, J. D. (1991) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610070202 · Cited by 63 · see citing works
Perros, P., Simpson, A. J., Innes, J. A., Teale, J. D., & McKnight, J. A. (1996) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1996.721542.x · Cited by 62 · see citing works
Management of postgastric bypass noninsulinoma pancreatogenous hypoglycemia
Mathavan, V. K., Arregui, M., Davis, C., Singh, K., Patel, A., & Meacham, J. (2010) · Surgical Endoscopy · doi:10.1007/s00464-010-1001-6 · Cited by 61 · see citing works
Alvarez, G. C., Faria, E. N., Beck, M., Girardon, D. T., & Machado, A. C. (2007) · Obesity Surgery · doi:10.1007/s11695-007-9096-0 · Cited by 61 · see citing works
Hypoglycemia in Patients with Non-Isiet Cell Tumors
Daughaday, W. H. (1989) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30390-6 · Cited by 59 · see citing works
Unexpected hypoglycemia in a critically ill patient.
Bates, D. W. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-2-200207160-00009 · Cited by 58 · see citing works
Pitei, D. L., Watkins, P., & EDMONDS, M. E. (1997) · Diabetic Medicine · doi:10.1002/(sici)1096-9136(199704)14:4 · Cited by 53 · see citing works
Service, F. J. (1974) · Archives of Internal Medicine · doi:10.1001/archinte.1974.00320200146022 · Cited by 51 · see citing works
Laparoscopic Conversion of the Gastric Bypass into a Normal Anatomy
HIMPENS, J. M., Dapri, G., & Cadière, G. (2006) · Obesity Surgery · doi:10.1381/096089206777822179 · Cited by 51 · see citing works
Meyer, G., Hackemann, A., Reusch, J., & Badenhoop, K. (2012) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2011.0158 · Cited by 50 · see citing works
González-González, A., Delgado, M., & Fraga-Fuentes, M. (2013) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2011.05.010 · Cited by 50 · see citing works
Park, S., Kim, D.-G., Suh, G. Y., Kang, J. G., Ju, Y., Lee, Y., Park, J. Y., Lee, S. W., & Jung, K. (2012) · Critical Care · doi:10.1186/cc11674 · Cited by 50 · see citing works
Teale, J. D., Blum, W. F., & Marks, V. (1992) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456329202900312 · Cited by 49 · see citing works
Hypoglycemia in patients with non-islet cell tumors.
Daughaday, W. H. (1989) · PubMed · Cited by 45 · see citing works
CRYER, P. E., WHITE, N. H., & SANTIAGO, J. V. (1986) · Endocrine Reviews · doi:10.1210/edrv-7-2-131 · Cited by 43 · see citing works
Insulin Immunoassays in the Detection of Insulin Analogues in Factitious Hypoglycemia
Neal, J. M., & Han, W. (2008) · Endocrine Practice · doi:10.4158/ep.14.8.1006 · Cited by 43 · see citing works
Laparoscopic Central Pancreatectomy
Machado, M. A. C., Surjan, R. C. T., Epstein, M. G., & MAKDISSI, F. F. (2013) · Surgical Laparoscopy Endoscopy & Percutaneous Techniques · doi:10.1097/sle.0b013e3182a4bf69 · Cited by 42 · see citing works
The therapeutic challenge of a nonresectable solitary fibrous tumor in a hypoglycemic patient
de Boer, J., Jager, P. L., Wiggers, T., Nieboer, P., Wymenga, A. N. M., Pras, E., Hoogenberg, K., Sleijfer, D. T., Suurmeijer, A. J. H., & van der Graaf, W. T. A. (2006) · International Journal of Clinical Oncology · doi:10.1007/s10147-006-0606-1 · Cited by 41 · see citing works
Escobar, G. A., Robinson, W. A., Nydam, T. L., Heiple, D. C., Weiss, G. J., Buckley, L., Gonzalez, R. C., & McCarter, M. D. (2007) · BMC Cancer · doi:10.1186/1471-2407-7-13 · Cited by 41 · see citing works
Effects of glucagon like peptide-1 to mediate glycemic effects of weight loss surgery
Salehi, M., & D’Alessio, D. A. (2014) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-014-9291-y · Cited by 40 · see citing works
SANFORD, J. P., & FAVOUR, C. B. (1956) · Annals of Internal Medicine · doi:10.7326/0003-4819-45-1-56 · Cited by 38 · see citing works
Non-islet cell tumor-induced hypoglycemia: a report of five cases and brief review of the literature
Dutta, P. R., Aggarwal, A., Gogate, Y., Nahar, U., Shah, V. N., Singla, M., Khandelwal, N. K., & Bhansali, A. K. (2013) · Endocrinology Diabetes and Metabolism Case Reports · doi:10.1530/edm-13-0046 · Cited by 38 · see citing works
Mitosis identification in diffuse gliomas
Coons, S. W., & Pearl, D. K. (1998) · Cancer · doi:10.1002/(sici)1097-0142(19980415)82:8 · Cited by 27 · see citing works
Hyperinsulinemic hypoglycemia following gastric bypass surgery for obesity.
Goldfine, A. B., Mun, E., & Patti, M. E. (2006) · Current Opinion in Endocrinology and Diabetes · doi:10.1097/01.med.0000244222.91280.71 · Cited by 26 · see citing works
Two Cases of Methimazole-Induced Insulin Autoimmune Syndrome in Graves' Disease
Roh, E., Kim, Y. A., Ku, E. J., Bae, J. H., Kim, H. M., Cho, Y. M., Park, Y. J., Park, K. S., Kim, S. Y., & Kwak, S. H. (2013) · Endocrinology and Metabolism · doi:10.3803/enm.2013.28.1.55 · Cited by 24 · see citing works
Application of Ga68‐ DOTA ‐exendin‐4 PET / CT to localize an occult insulinoma
Cuthbertson, D. J., Banks, M. A., Khoo, B. C. E., Antwi, K., Christ, E., Campbell, F., Raraty, M. G. T., & Wild, D. (2015) · Clinical Endocrinology · doi:10.1111/cen.12973 · Cited by 24 · see citing works
The epidemiology and significance of autoimmune diseases in health care
Cervera, R. (2001) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/003655101753352013 · Cited by 23 · see citing works
Islet cell tumors of the pancreas.
Whipple, A. O. (1952) · PubMed Central · Cited by 23 · see citing works
Katz, L. E., Liu, F., Baker, B. K., Agus, M. S. D., Nunn, S. E., Hintz, R. L., & Cohen, P. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.3.1141 · Cited by 22 · see citing works
Insulin autoimmune syndrome: case report
Moreira, R. O., Lima, G. A. B., Peixoto, P. C. B., Farias, M. L. F., & Vaisman, M. (2004) · Sao Paulo Medical Journal · doi:10.1590/s1516-31802004000400010 · Cited by 20 · see citing works
Agus, M. S. D., Katz, L. E. L., Satin-Smith, M. S., Meadows, A. T., Hintz, R. L., & Cohen, P. (1995) · The Journal of Pediatrics · doi:10.1016/s0022-3476(95)70071-4 · Cited by 20 · see citing works
A 67-Year-Old Woman with Recurrent Hypoglycemia: Non-Islet Cell Tumour Hypoglycemia
Ma, R. C. W. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.050422 · Cited by 14 · see citing works
[Insulin autoimmune syndrome revealing systemic lupus erythematosus].
Rouabhia, S., Ramanoelina, J., Godmer, P., Reach, G., Dutel, J.-L., & Guillevin, L. (2003) · PubMed · Cited by 13 · see citing works
Islet-cell Tumors of the Pancreas
Waugh, J. M. (1952) · Surgical Clinics of North America · doi:10.1016/s0039-6109(16)33688-x · Cited by 13 · see citing works
Munchausen's syndrome by proxy web-mediated in a child with factitious hyperglycemia
Vanelli, M. (2002) · The Journal of Pediatrics · doi:10.1067/mpd.2002.129976 · Cited by 12 · see citing works
Rose, M. G., Tallini, G., Pollak, J., & Murren, J. R. (1999) · PubMed · Cited by 12 · see citing works
Treatment of Tumour-Induced Hypoglycaemia with Human Growth Hormone
Khaleeli, A. A., Perumainar, M., Spedding, A., Teale, J. D., & Marks, V. (1992) · Journal of the Royal Society of Medicine · doi:10.1177/014107689208500525 · Cited by 12 · see citing works
Yj, L., Sj, S., Jk, T., Liu, W., & Jh, T. (1987) · PubMed · Cited by 9 · see citing works
Prime-Time Hypoglycemia: Factitious Hypoglycemia During Insulin-Pump Therapy
Osipoff, J. N., Sattar, N., Garcia, M., & Wilson, T. A. (2010) · PEDIATRICS · doi:10.1542/peds.2009-1830 · Cited by 9 · see citing works
Laparoscopic central pancreatectomy for insulinoma (with video)
Villacreses, D., Stauffer, J. A., Horácio, J. G., & Asbun, J. (2016) · Journal of Visceral Surgery · doi:10.1016/j.jviscsurg.2016.06.004 · Cited by 2 · see citing works
Egger, M., Davey Smith, G., Stettler, C., & Diem, P. (1997) · Diabetic Medicine · doi:10.1002/(sici)1096-9136(199711)14:11
Flagged first, then by citations
1 of the 121 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Machine Learning Techniques for Hypoglycemia Prediction: Trends and Challenges
Mujahid, O., Contreras, I., & Vehı́, J. (2021) · Sensors · doi:10.3390/s21020546 · Cited by 88 · see citing works
Nutritional guidelines for the management of insulin resistance
Muscogiuri, G., Barrea, L., Caprio, M., Ceriani, F., Chavez, A. O., El Ghoch, M., Frias-Toral, E., Mehta, R. J., Mendez, V., Paschou, S. A., et al. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1908223 · Cited by 63 · see citing works
Bischoff, S. C., Barazzoni, R., Busetto, L., Campmans-Kuijpers, M. J. E., Cardinale, V., Chermesh, I., Eshraghian, A., Kani, H. T., Khannoussi, W., Lacaze, L., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.07.003 · Cited by 61 · see citing works
The functioning side of the pancreas: a review on insulinomas
Maggio, I., Mollica, V., Brighi, N., Lamberti, G., Manuzzi, L., Ricci, A. D., & Campana, D. (2019) · Journal of Endocrinological Investigation · doi:10.1007/s40618-019-01091-w · Cited by 59 · see citing works
Bischoff, S. C., Barazzoni, R., Busetto, L., Campmans-Kuijpers, M. J. E., Cardinale, V., Chermesh, I., Eshraghian, A., Kani, H. T., Khannoussi, W., Lacaze, L., et al. (2022) · United European Gastroenterology Journal · doi:10.1002/ueg2.12280 · Cited by 54 · see citing works
Clinico–pathological features, treatments and survival of malignant insulinomas: a multicenter study
Veltroni, A., Cosaro, E., Spada, F., Fazio, N., Faggiano, A., Colao, A. M. L., Pusceddu, S., Zatelli, M. C., Campana, D., Piovesan, A., et al. (2020) · European Journal of Endocrinology · doi:10.1530/eje-19-0989 · Cited by 49 · see citing works
Bischoff, S. C., Ockenga, J., Eshraghian, A., Barazzoni, R., Busetto, L., Campmans-Kuijpers, M. J. E., Cardinale, V., Chermesh, I., Kani, H. T., Khannoussi, W., et al. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.03.021 · Cited by 45 · see citing works
Jensen, M. H., Dethlefsen, C., Hejlesen, O. K., & Vestergaard, P. (2019) · Acta Diabetologica · doi:10.1007/s00592-019-01447-x · Cited by 41 · see citing works
Selenium deficiency is linearly associated with hypoglycemia in healthy adults
Wang, Y., Rijntjes, E., Wu, Q., Lv, H., Gao, C., Shi, B., & Schomburg, L. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101709 · Cited by 39 · see citing works
Clinical Presentation and Diagnostic Approach to Hypoglycemia in Adults Without Diabetes Mellitus
Palani, G., Stortz, E., & Moheet, A. (2023) · Endocrine Practice · doi:10.1016/j.eprac.2022.11.010 · Cited by 29 · see citing works
Lv, X., Fang, K., Hao, W., Han, Y., Yang, N., & Yu, Q. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s280084 · Cited by 26 · see citing works
Insulin autoimmune syndrome induced by exogenous insulin injection: a four-case series
Shen, Y.-M., Song, X., & Ren, Y. (2019) · BMC Endocrine Disorders · doi:10.1186/s12902-019-0482-0 · Cited by 25 · see citing works
Rania, M., Caroleo, M., Carbone, E. A., Ricchio, M., Pelle, M. C., Zaffina, I., Condoleo, F., de Filippis, R., Aloi, M., Fazio, P. D., et al. (2023) · Journal of Eating Disorders · doi:10.1186/s40337-023-00891-z · Cited by 19 · see citing works
Li, C., Chai, X., Pan, J., Huang, J., Wu, Y., Xue, Y., Zhou, W., Yang, J., Zhu, X., & Zhao, S. (2022) · Journal of Molecular Neuroscience · doi:10.1007/s12031-022-01974-3 · Cited by 16 · see citing works
Insulinoma in childhood: a retrospective review of 22 patients from one referral centre
Melikyan, M. A., Gubaeva, D. N., Shadrina, A., Викторовна, Б. А., Kareva, M., Tiulpakov, A. N., Efremenkov, A. M., Sokolov, Y., Brusgaard, K., Christesen, H. T., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1127173 · Cited by 16 · see citing works
Almagthali, A., Alsohimi, S., Alkhalaf, A., Sulaiman, K. A. A., & Aljuhani, O. A. (2024) · Scientific Reports · doi:10.1038/s41598-024-57403-5 · Cited by 17 · see citing works
Innaurato, S., Brierley, G. V., Grasso, V., Massimi, A., Gaudino, R., Sileno, S., Bernardini, S., Semple, R. K., & Barbetti, F. (2018) · Pediatric Diabetes · doi:10.1111/pedi.12632 · Cited by 13 · see citing works
Kumar, S., Melek, M., & Rohl, P. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.906012 · Cited by 12 · see citing works
Insulinoma in pregnancy (a case presentation and systematic review of the literature)
Dobrindt, E. M., Mogl, M. T., Goretzki, P. E., Pratschke, J., & Dukaczewska, A. (2021) · Rare Tumors · doi:10.1177/2036361320986647 · Cited by 11 · see citing works
Clopidogrel as a Distinctive Cause of Insulin Autoimmune Syndrome: A Systematic Case Review
Chen, S., Qiang, J.-Q., Zhao, B.-L., Tian, R., Yuan, T., Li, M., Li, M., Gu, Z.-Q., Yang, L., Zhu, H., et al. (2023) · Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy · doi:10.2147/dmso.s418845 · Cited by 9 · see citing works
Hypervascular pancreatic “lesions”: a pattern-based approach to differentiation
Shankar, P. R., Wasnik, A. P., Al-Hawary, M. M., Francis, I. R., & Kaza, R. K. (2017) · Abdominal Radiology · doi:10.1007/s00261-017-1363-5 · Cited by 10 · see citing works
Spada, F., Rossi, R. E., Kara, E., Laffi, A., Massironi, S., Rubino, M., Grimaldi, F., Bhoori, S., & Fazio, N. (2021) · Pharmaceuticals · doi:10.3390/ph14060539 · Cited by 10 · see citing works
CGM for insulinoma screening: a prospective and observational case-control study
Ma, J., Huang, X., Zhao, J., Lu, J., Lu, W., Bao, Y., Zhou, J., & Han, J. (2021) · Endocrine Related Cancer · doi:10.1530/erc-20-0447 · Cited by 9 · see citing works
Funktionsdiagnostik in der Endokrinologie
Auernhammer, C. J., & Reincke, M. (2017) · Der Internist · doi:10.1007/s00108-017-0360-7 · Cited by 9 · see citing works
Novel pyrazolyl-thiazoles: synthesis, characterization and study of their antidiabetic properties
(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac104.849854 · Cited by 9 · see citing works
Chen, S., Qiang, J., Zhang, Y., Zhao, B., Tian, R., Yuan, T., Li, M., Li, M., Li, Y., Zhu, H., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1091933 · Cited by 9 · see citing works
Ademolu, A. B. (2020) · International Journal of Diabetes and Endocrinology · doi:10.11648/j.ijde.20200502.12 · Cited by 7 · see citing works
Hypoglycemia in the emergency, is there any effect on endothelial and diastolic functions?
Akhan, O., & Ardahanlı, İ. (2021) · Echocardiography · doi:10.1111/echo.14988 · Cited by 7 · see citing works
Walker, M. P., Shenoy, V., Metz, D. C., Stanley, C. A., Fraker, D. L., Chandrasekhara, V., & Amaro, A. (2022) · BMC Endocrine Disorders · doi:10.1186/s12902-022-01219-9 · Cited by 7 · see citing works
Hanai, S., Iwata, M., & Terasawa, T. (2019) · Internal Medicine · doi:10.2169/internalmedicine.2339-18 · Cited by 6 · see citing works
Yu, J., Liu, Y., Lyu, L., Zhao, Y. Z., Qi, M., Ping, F., Xu, L., Li, W., Xu, Q., Zhang, H., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.994707 · Cited by 6 · see citing works
Rötgens, J., Lapauw, B., & T'Sjoen, G. G. (2023) · Acta Clinica Belgica · doi:10.1080/17843286.2023.2165652 · Cited by 6 · see citing works
Dieterle, M. P., Husari, A., Prozmann, S. N., Wiethoff, H., Stenzinger, A., Röhrich, M., Pfeiffer, U., Kießling, W. R., Engel, H., Sourij, H., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11061741 · Cited by 5 · see citing works
“Apart from severe diseases like liver, kidney or heart failure, the intake of alcohol, insulin, or insulin secretagogues needs to be ruled out [7,9,10].”
BackgroundRisk factors for hypoglycaemia in adults with type 1 diabetes: a systematic review and meta-analysis
Zhang, Q. X., Zhou, H., Lin, R., Hu, L., & Zhu, X. (2025) · BMC Endocrine Disorders · doi:10.1186/s12902-025-02122-9 · Cited by 5 · see citing works
Distinct Metabolic States Are Observed in Hypoglycemia Induced in Mice by Ricin Toxin or by Fasting
Kempa, J., O’Shea-Stone, G. P., Moss, C. E., Peters, T. R., Marcotte, T. K., Tripet, B., Eilers, B. J., Bothner, B. B., Copié, V., & Pincus, S. H. (2022) · Toxins · doi:10.3390/toxins14120815 · Cited by 4 · see citing works
Rania, M., Procopio, A., Zaffino, P., Carbone, E. A., Fiorentino, T. V., Andreozzi, F., Segura‐Garcìa, C., Cosentino, C., & Arturi, F. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03281-y · Cited by 5 · see citing works
Ahmed, F. W., Majeed, M. S., & Kirresh, O. Z. (2021) · StatPearls · Cited by 5 · see citing works
Metastatic Insulinoma Presenting With Postprandial Hypoglycemia
Maher, M. D., Desai, D. N., & Bajaj, M. (2022) · AACE Clinical Case Reports · doi:10.1016/j.aace.2022.03.002 · Cited by 5 · see citing works
IGF-2 Induced Hypoglycemia Associated with Lung Sarcoma
Gherbon, A. (2022) · Acta Endocrinologica (Bucharest) · doi:10.4183/aeb.2022.232 · Cited by 5 · see citing works
Associations of Colonoscopy and Risk of Hypoglycemia in Patients with Type 2 Diabetes
Yang, H., Liu, D., Zeng, L., Peng, S., & Liu, H. (2023) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s401903 · Cited by 5 · see citing works
Gluhcheva, Y., Pashkunova-Martic, I., Schaier, M., Владов, И., Stoykova, S., Petrova, E., Pavlova, E., Dorkov, P., Helbich, T. H., Keppler, B. K., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084368 · Cited by 5 · see citing works
Gaikwad, S. R., Bontha, M. R., Devi, S., & Dumbre, D. (2024) · Public Health Nursing · doi:10.1111/phn.13440 · Cited by 4 · see citing works
Is the Size of Insulinoma Predictive for its Endocrine Behavior? An Endoscopic Ultrasound Study
Adelmeyer, J., Göbel, F., & Kann, P. H. (2022) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-1840-7492 · Cited by 4 · see citing works
Cai, J., Chen, H., Lu, M., Zhang, Y., Lu, B., Luo, C., Feng, X., You, L., Dai, M., & Zhao, Y. (2022) · Cancers · doi:10.3390/cancers14143403 · Cited by 4 · see citing works
Experimental pharmacological approaches to reverse impaired awareness of hypoglycemia—a review
Hashmi, H. Z., Khowaja, A. A., & Moheet, A. A. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1349004 · Cited by 4 · see citing works
Insulin Autoimmune Syndrome – An After-Meal Roller Coaster Ride
Low, C. K., Wong, H. C., Apparow, S., & Yong, S. L. (2024) · Journal of the ASEAN Federation of Endocrine Societies · doi:10.15605/jafes.039.01.07 · Cited by 3 · see citing works
Metastatic insulinoma presenting after bariatric surgery in a patient diagnosed with MEN1
Poku, C. A., Amjed, H., Kazi, F. M., & Samarasinghe, S. (2022) · Clinical Case Reports · doi:10.1002/ccr3.5419 · Cited by 3 · see citing works
Case Report: Artifactual Hypoglycemia: A Condition That Should Not Be Forgotten
Amaral, S., Palha, A. M., Bernardino, V., & Silva‐Nunes, J. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.951377 · Cited by 3 · see citing works
Pincus, S. H., Kyro, A., Maresh, G. A., Peters, T. R., Kempa, J., Marcotte, T. K., Gao, Z., Ye, J., Copié, V., & Song, K. (2022) · Toxins · doi:10.3390/toxins14120820 · Cited by 3 · see citing works
Husna, C., & Saputra, B. A. (2020) · Jurnal Ilmu Keperawatan Medikal Bedah · doi:10.32584/jikmb.v3i2.515 · Cited by 3 · see citing works
Cannavò, S., & Cannavò, S. P. (2021) · Endocrinology Diabetes and Metabolism Case Reports · doi:10.1530/edm-21-0065 · Cited by 3 · see citing works
Sulfasalazine-Induced Hypoglycemia in a Patient with Type 2 Diabetes and End-Stage Renal Disease
Stamatiades, G. A., Echouffo-Tcheugui, J. B., & Garber, J. R. (2018) · AACE Clinical Case Reports · doi:10.4158/accr-2018-0067 · Cited by 3 · see citing works
Managing Adults With Hypoglycemia
Watson, C. J., & Edlow, J. A. (2023) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2023.07.019 · Cited by 2 · see citing works
Wu, H., Yang, Y., Zhao, C., Lyu, X., Li, J., Lei, J., Liu, M., Hu, X., Deng, Y., He, Y., et al. (2025) · PLoS Medicine · doi:10.1371/journal.pmed.1004667 · Cited by 2 · see citing works
Postprandial Hypoglycemia Associated With Insulin Receptor Gene Variant G1146R
Delacruz, L., Adamczak, L. J., & Astapova, O. (2025) · JCEM Case Reports · doi:10.1210/jcemcr/luaf247 · Cited by 2 · see citing works
Dholariya, S. J., Parchwani, D. N., Dutta, S., & Singh, R. (2022) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2023.2138343 · Cited by 2 · see citing works
Hypoglycemic disorders in adults
Dhanasekaran, M., & Vella, A. V. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91707-0.00004-8 · Cited by 2 · see citing works
Self-citationTumour-induced hypoglycaemia: a narrative review
Barber, T. M., Bannon, C. A. M., Weickert, M. O., Kyrou, I., & Randeva, H. S. (2021) · Journal of Laboratory and Precision Medicine · doi:10.21037/jlpm-20-110 · Cited by 1 · see citing works
Hofland, J., & de Herder, W. W. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13825-6.00061-3 · Cited by 2 · see citing works
DİYABETİK OLMAYAN HASTALARDA HİPOGLİSEMİ
Erbatur, N. H., & Kuşkonmaz, Ş. (2022) · Kocatepe Tıp Dergisi · doi:10.18229/kocatepetip.953519 · Cited by 1 · see citing works
Autoimmune polyglandular syndrome with shock and high anion gap metabolic acidosis
Kounatidis, D. C., Kontos, G. A., Kotsi, E., Kaparou, P., Avgoustou, E., Vallianou, N. G., Deutsch, M. J., & Vassilopoulos, D. (2024) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2024.05.019 · Cited by 1 · see citing works
Peng, G., Sun, R., Lei, X., Deng, C., Leng, W., Zhang, X., Wu, Y.-L., Xie, L., Hong, P., Long, M., et al. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1681861 · Cited by 1 · see citing works
Asymptomatic Hyperinsulinaemic Hypoglycaemia
Ferreira, A., Barbosa, M. S., Coelho, R., & Lourenço, P. (2020) · European Journal of Case Reports in Internal Medicine · doi:10.12890/2020_001827 · Cited by 1 · see citing works
Spontanhypoglykämien: Eine diagnostische Herausforderung
Adelmeyer, J., Goebel, J. N., & Kann, P. H. (2021) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/a-1581-4724 · Cited by 1 · see citing works
Gomes, V., & Ferreira, F. (2019) · Journal of Endocrinology and Metabolism · doi:10.14740/jem617 · Cited by 1 · see citing works
The Occult Insulinoma Was Localized Using Endoscopic Ultrasound Guidance: A Case Report
Guo, Z., chen, Y., Liu, R., & Chen, Y. (2025) · Clinical Case Reports · doi:10.1002/ccr3.9634 · Cited by 1 · see citing works
Insulinoma: Uma Causa Rara de Hipoglicemia
Matta-Coelho, C., Monteiro, A. M., & Marques, O. (2018) · Gazeta Médica · doi:10.29315/gm.v4i4.87 · Cited by 1 · see citing works
Quantification of Insulin Analogs by Liquid Chromatography–High-Resolution Mass Spectrometry
Fatica, E. M., Larkey, N. E., & Singh, R. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2565-1_20 · Cited by 1 · see citing works
Belay, K. E., Belay, S., Asrat, Y., Efrem, P., & Alemneh, T. A. (2023) · Journal of Medical Case Reports · doi:10.1186/s13256-023-04166-8 · Cited by 1 · see citing works
Der Diabetespatient in der Notfallversorgung
Hans, F. P., & Busch, H.-J. (2018) · Der Diabetologe · doi:10.1007/s11428-017-0298-3
Der Diabetespatient in der Notfallversorgung
Hans, F. P., & Busch, H.-J. (2018) · Notfall + Rettungsmedizin · doi:10.1007/s10049-018-0497-5
Treatment of Neuroendocrine Tumour Disease
Moore, A. R., & Yip, V. S. K. (2018) · Springer eBooks · doi:10.1007/978-3-319-92216-4_20
UN INSOLITO CASO DI IPOGLICEMIA IPERINSULINEMICA DA NESIDIOBLASTOSI E INSULINOMA
Dardano, A., Barone, S., Daniele, G., Kurumthodathu, J. J., Prato, S. D., & Miccoli, R. (2018) · il Diabete · doi:10.30682/ildia1804h
Acil servise başvuran hipoglisemili olguların etiyolojik yönden incelenmesi
Çadırcı, K., Bayrak, M., Keskin, H., & Gür, S. T. A. (2020) · Anatolian Current Medical Journal · doi:10.38053/agtd.690557
Upton, J. E. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-43205-8_7
Nicht-Diabetes-assoziierte Hypoglykämien
Treiber, G. M. (2020) · Journal für Klinische Endokrinologie und Stoffwechsel · doi:10.1007/s41969-020-00124-7
Hypoglycemia In The Emergency, But What Awaits Us For Cardiac Risks In The Future?Preprint
Akhan, O., & Ardahanlı, İ. (2021) · doi:10.22541/au.161003343.32075984/v1
Hyperinsulinemic hypoglycemia, clinical considerations and a case report of a novel GCK mutation
Kraslow, M., Miller, A., Memon, R., Pinault, L. F., Steinle, N., & Spanakis, I. (2021) · Journal of Clinical and Translational Endocrinology Case Reports · doi:10.1016/j.jecr.2021.100084
Tykhonova, T., Barabash, N., & Soldatenko, I. (2020) · The Journal of V N Karazin Kharkiv National University series Medicine · doi:10.26565/2313-6693-2020-39-15
A case of reactive hypoglycemia caused by Kampo medicine
Yamasaki, G. (2021) · Traditional & Kampo Medicine · doi:10.1002/tkm2.1282
FEAR OF HYPOGLYCEMIA IN TYPE 1 DIABETES MELLITUS
Markanovic, H. (2021)
Anestesia y diabetes en el perioperatorio
Ramírez, A. Y. L., Molina, N. E. C., & García, J. P. A. O. (2021) · Anales Médicos de la Asociación Médica del Centro Médico ABC · doi:10.35366/101667
(2021) · Elsevier eBooks · doi:10.1016/b978-3-437-21921-4.00246-4
FREITAS, G. B. L. D., Evaristo, T. A. D. O., & Holanda, É. C. (2022) · Editora Pasteur eBooks · doi:10.29327/560936.1-12
Zandee, W. T., & de Herder, W. W. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65228-5
Gutiérrez, M. S. C., & Ochoa, R. I. Á. (2022) · Tesla Revista Científica · doi:10.55204/trc.v9789i8788.79
Paraneoplastic Hypoglycemia: A Case Report
Benkacem, M., Smouni, M., Lahbib, H., Rachidi, S. A., & Mrabet, F. E. (2022) · Saudi Journal of Medicine · doi:10.36348/sjm.2022.v07i08.002
Non-invasive Hypoglycemia Regulatory Patch with Glucagon Administration
Gonzalez-Martinez, J. M., Méndez-Sánchez, J. E., Ramirez-Fernandez, O., Cipriano-Urbano, I., & Camporredondo, E. (2022) · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany · doi:10.1007/978-3-031-18256-3_25
Hiperwarburgismo: la “hipoglucemia feliz” de los pacientes oncológicos
Roosemberg, F., Veliz-Rivas, J. A., Uscocovich, V. J. O., Flores, A. E. B., & Cruz, C. G. (2022) · Oncología (Ecuador) · doi:10.33821/626
Insulinoma misdiagnosed as factitious hypoglycemia
Bala, N. M., Aragüés, J. M., Guerra, S., Peixe, M., & Valadas, C. (2023) · Revista Portuguesa de Endocrinologia Diabetes e Metabolismo · doi:10.26497/cc210046
Evaluating Biomedical Features for Reactive Hypoglycaemia Prediction with Machine Learning
Dany, F., & Retiaty, F. (2023) · doi:10.2991/978-94-6463-112-8_11
Nurjannah, M., & Asthiningsih, N. W. W. (2023) · Jurnal Keperawatan Soedirman · doi:10.20884/1.jks.2023.18.1.5281
Recurrent Episodes of Weakness, Sweating, and Tremors
Silvey-Lee, K., Kuhnly, N., & Chen, L. L. (2023) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2023.104837
Перспективи використання безперервного моніторингу рівня глюкози у хворих з інсуліномою
Kondratyshyn, A. R., Fik, M. S., Коваль, А.-М., Naumova, L. V., & Khomitskiy, S. B. (2023) · Endokrynologia · doi:10.31793/1680-1466.2023.28-1.90
Stars and Rising Stars in Pediatric Endocrinology: 2022
(2024) · Frontiers research topics · doi:10.3389/978-2-8325-4686-4
Literature Review: Teh Manis Kurang Efektif Untuk Menangani Hipoglikemia
Choeron, R. C., & Nofiana, I. (2024) · Care Jurnal Ilmiah Ilmu Kesehatan · doi:10.33366/jc.v12i1.5673
ZaŽivljenje! Izbor poglavij na temo prve pomoči
Klement, B. (2024) · doi:10.18690/um.mf.2.2024
The occult insulinoma was localized using endoscopic ultrasound guidance:A case reportPreprint
chen, Y., Guo, Z., Liu, R., & chen, Y. (2024) · doi:10.22541/au.172480587.73977680/v1
A clinical case of factitious hypoglycemia in a patient with type 1 diabetes mellitus
Ivanova, D. S., Дзагахова, А. В., Сергеевна, М. М., Ibragimova, L. I., & Yukina, M. Y. (2024) · Diabetes Mellitus · doi:10.14341/dm13155
28-Year-Old Woman With Undifferentiated Spells
Moazzami, M., Mohan, S., & Egan, A. M. (2025) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2024.04.019
- Authors
- Kittah, N. E., & Vella, A.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Vella, Adrian
- ORCID
- Vella, Adrian
- Venue
- European Journal of Endocrinology
- Publisher
- Oxford University Press (OUP)
- Published
- 2017-07
- Volume
- 177
- Issue
- 1
- Pages
- R37-R47
- ISSN
- 0804-4643 (ISSN-L)
- 1479-683X
- OpenAlex
- W2604577308
- Cited by
- 107
- References
- 121
- Citations by year
- 2026: 2 · 2025: 12 · 2024: 11 · 2023: 17 · 2022: 23 · 2021: 16 · 2020: 11 · 2019: 5 · 2018: 8 · 2017: 2
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Keywords
- hypoglycemia, hypoglycemia management, Whipple's triad, insulinoma, post-bariatric hypoglycemia, insulin antibodies, drug-induced hypoglycemia, non-islet cell tumor hypoglycemia, factitious hypoglycemia, glucose regulation
- MeSH terms
- Diabetes Mellitus, Humans, Hypoglycemia, Pancreatic Neoplasms, Disease Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review