Cited by 43Pelvic floor disorders treatmentsUterine Myomas and TreatmentsUreteral procedures and complications

Risk factors for recurrence after hysterectomy plus native-tissue repair as primary treatment for genital prolapse

Manodoro, Stefano, Frigerio, Matteo, Cola, Alice, Spelzini, Federico, Milani, Rodolfo·2018·International Urogynecology Journal

Abstract

Introduction and hypothesis Identification of risk factors for pelvic organ prolapse (POP) recurrence is crucial to provide adequate preoperative counselling and tailor surgical treatment. The aim of this retrospective study was to identify risk factors for recurrence in a large series of patients with POP treated with primary transvaginal native-tissue repair involving high uterosacral ligament suspension.Methods Postoperative descent of POP-Q stage 2 or higher in any compartment was considered as recurrence. Global recurrence (GR) was defined as any recurrence in any compartment irrespective of the surgical procedures performed during primary prolapse surgery. True recurrence (TR) was defined as recurrence in a compartment repaired during primary prolapse surgery.Results Of a total of 533 eligible women, 519 were available for follow-up. Univariate analysis showed that age ≤50 years, premenopausal status, obesity (BMI >30 kg/m 2), history of severe macrosomia (>4,500 g), preoperative POP stage 3 or higher and absence of anterior repair at the time of POP surgery were risk factors for GR. Multivariate analysis confirmed lack of posterior repair (odds ratio, OR, 1.8), severe macrosomia (OR 2.7), premenopausal status (OR 3.9), obesity (OR 2.2) and preoperative stage 3 or higher (OR 2.6) as risk factors for GR. Univariate analysis showed that premenopausal status and preoperative POP stage 3 or higher were risk factors for TR. Multivariate analysis confirmed premenopausal status (OR 4.0) and preoperative stage 3 or higher (OR 4.5) as risk factors for TR.Conclusions This study confirmed preoperative stage 3 or higher as a risk factor for prolapse recurrence. The study also identified additional risk factors for surgical failure including lack of posterior repair, severe macrosomia, premenopausal status and obesity.

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Crossref · 10.1007/s00192-017-3448-7

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Authors
Manodoro, S., Frigerio, M., Cola, A., Spelzini, F., & Milani, R.
Affiliations
  • Azienda Ospedaliera San Gerardo (IT)
  • Ospedale Infermi di Rimini (IT)
Corresponding author
Manodoro, Stefano
Venue
International Urogynecology Journal
Published
2017-08-16
Volume
29
Issue
1
Pages
145-151
ISSN
  • 0937-3462 (ISSN-L)
  • 1433-3023
OpenAlex
W2747550651
Cited by
43
References
25
Citations by year
2026: 2 · 2025: 2 · 2024: 8 · 2023: 6 · 2022: 6 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 5 · 2017: 1
FWCI
3.82
Type
journal article
Language
en
Open access
closed
Locations
  • International Urogynecology Journal (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
  • Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
  • Health Sciences › Medicine › Obstetrics and Gynecology › Ureteral procedures and complications
Keywords
pelvic organ prolapse, prolapse recurrence, risk factors, hysterectomy, native tissue repair, transvaginal repair, uterosacral ligament suspension, posterior repair, premenopausal status, obesity, macrosomia, POP-Q stage
MeSH terms
Aged, Female, Follow-Up Studies, Humans, Hysterectomy, Middle Aged, Obesity, Recurrence, Retrospective Studies, Risk Factors, Severity of Illness Index, Multivariate Analysis, Treatment Outcome, Premenopause, Plastic Surgery Procedures, Suburethral Slings, Pelvic Organ Prolapse

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