Anatomic and functional assessment and risk factors of recurrent prolapse after vaginal sacrospinous fixation
Abstract
Background. To identify risk factors in recurrence and to evaluate anatomic and functional results of vaginal sacrospinous ligament fixation and pelvic floor reconstruction for genital prolapse. Methods. One hundred and thirty‐eight women underwent surgery for uterovaginal or vault prolapse. Follow‐up data were available for 122 cases; 83% were examined and others were interviewed by telephone. The median (range) follow‐up was 24 (1–141) months. Cox regression was used to identify risk factors associated with recurrence; uni‐ and multivariate regression was used to identify risk factors underlying postoperative infections because infections were found to be a risk factor of recurrence. Recurrence‐free survival was estimated using the Kaplan–Meier method. Results. Seven (5%) patients suffered severe cardiopulmonary complications including one postoperative death due to a pulmonary embolism. Twenty‐six (21%) patients suffered a recurrence, 14 with cystocele. Ten patients with recurrence were symptomatic and six underwent a re‐operation. The Cox regression model showed that vaginal cuff infection raised the odds ratio (OR) for recurrence to 6.13 [confidence interval (CI) 1.80–20.83] and urinary tract infection to 3.65 (CI 1.40–9.47). In both uni‐ and multivariate analysis, lack of intravenous antibiotic prophylaxis, age less than 73 years and vaginal ulcerations were statistically significant risk factors for postoperative infection. Eleven (33%) out of 33 sexually active women reported improvement and three (9%) complained of dyspareunia. Conclusions. Transvaginal sacrospinous ligament fixation with pelvic floor repair is an effective means of correcting both vault prolapse and uterine procidentia. Women who wish to preserve coital function will also benefit from this operation. Postoperative infection is an independent and most important individual risk factor underlying recurrence. Prophylactic antibiotics seem to be effective in reducing the rate of postoperative infections.
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Previous studies have reported a higher risk of POP recurrence in younger patients using different cut-offs.
“Moreover, previous studies have reported a higher risk of POP recurrence in younger patients using different cut‐offs. 23 , 24 , 25”
From Native-tissue prolapse repair: Efficacy and adverse effects of uterosacral ligaments suspension at 10-year follow up (2022) · cites this paper as [24]
Younger women may have more inherent pathophysiological pelvic floor issues such as poor tissue quality and more neuromusculo-fascial damage than older women with the same degree of prolapse.
“This may be because younger women may have more inherent pathophysiological pelvic floor issues such as poor tissue quality and more neuromusculo-fascial damage compared with older women with the same degree of prolapse [12, 25].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [25]
The association of younger age with recurrence is consistent with other studies.
“The age factor is in correlation with other studies [12, 13, 25].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [25]
The recurrence rate in this study is comparable to rates reported in South Korea and Finland (17% and 21%).
“The recurrence rate in this study is comparable with that of other studies carried out in South Korea and Finland, with follow-up periods of up to 2 years, that reported recurrence rates of 17 and 21% respectively [24, 25].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [25]
Younger women are more likely to experience recurrence after surgery.
“age is an important factor in recurrence, as younger women are more likely to experience recurrence after surgery [25,30].”
From Recurrence Rate and Risk Factors for Apical Prolapse After Sacrospinous Ligament Fixation: A Prospective Cohort Study (2026) · cites this paper as [30]
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- Authors
- Nieminen, K., Huhtala, H., & Heinonen, P. K.
- Affiliations
- Tampere University Hospital (FI)
- Venue
- Acta Obstetricia et Gynecologica Scandinavica
- Publisher
- Wiley
- Published
- 2003-05
- Volume
- 82
- Issue
- 5
- Pages
- 471-478
- ISSN
- 0001-6349 (ISSN-L)
- 1600-0412
- OpenAlex
- W2119233927
- Cited by
- 102
- References
- 24
- Citations by year
- 2026: 2 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 4 · 2017: 10 · 2016: 5 · 2015: 2 · 2014: 3 · 2013: 1 · 2012: 3
- FWCI
- 2.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Obstetricia Et Gynecologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Tays
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Ureteral procedures and complications
- Keywords
- pelvic floor reconstruction, uterovaginal prolapse, vaginal vault prolapse, prolapse recurrence, risk factors, postoperative infection, urinary tract infection, dyspareunia, cystocele, postoperative complications
- MeSH terms
- Activities of Daily Living, Aged, Aged, 80 and over, Broad Ligament, Female, Finland, Humans, Middle Aged, Pulmonary Embolism, Quality of Life, Recurrence, Retrospective Studies, Risk Factors, Sacrococcygeal Region, Gynecologic Surgical Procedures, Time Factors, Urinary Tract Infections, Uterine Prolapse, Vagina, Multivariate Analysis, Proportional Hazards Models, Pelvic Floor, Antibiotic Prophylaxis
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