Risk Factors for the Recurrence of Pelvic Organ Prolapse
Open accessAbstract
Background/Aims: To investigate the risk factors for the recurrence of prolapse after traditional pelvic reconstructive surgery. Methods: The medical records of 212 patients who received traditional restorative reconstructive surgeries for symptomatic pelvic organ prolapse from March 1999 to April 2006 were retrospectively analyzed. Recurrence was defined as any prolapse of stage II or greater according to the Pelvic Organ Prolapse Quantification system. The log-rank test and Cox regression of the Kaplan-Meier survival analysis were used in univariate analysis, and the Cox proportional hazard model was used in multivariate analysis. Results: The median follow-up period was 24 (range 1–84) months and the number of patients suffering from recurrence was 36 (17.0%). Age, parity, repetitive heavy lifting/chronic constipation, family history, hormone replacement therapy status, and preoperative stage all had an influence on the outcome, although preoperative stage IV was the only independent risk factor (hazard ratio (HR) 5.6, 95% CI 1.1–29.3, p = 0.044). Analyzing by compartments, preoperative stage IV (HR 18.6, 95% CI 2.1–162.3, p = 0.018) was an independent risk factor for the recurrence in anterior compartment, not for posterior or apical. Conclusions: Patients with a far advanced preoperative stage (stage IV), especially in cases of anterior prolapse, are more likely to experience a recurrence after traditional reconstructive surgery.
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The higher recurrence rate reported by Vakili et al. (58% at 1 year) may be due to differences in the definitions of recurrence used.
“However, another study by Vakili et al. [16] reported a higher recurrence rate of 58% at 1 year after surgery. This contrast could be due to differences in the definitions of recurrence used. Vakili et al. [16] defined recurrence as any prolapse beyond stage zero according to the POP-Q system, whereas in this study we used POP-Q stage II or greater to define recurrence, as in other studies [12, 13”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [24]
The recurrence rate in this study is comparable to rates reported in South Korea and Finland (17% and 21%).
“The recurrence rate in this study is comparable with that of other studies carried out in South Korea and Finland, with follow-up periods of up to 2 years, that reported recurrence rates of 17 and 21% respectively [24, 25].”
From Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study (2022) · cites this paper as [24]
Recurrence rates following primary surgery range from 13 to 30% at 1-2 years, varying by definition and influenced by patient factors, anatomical features, and procedural elements.
“Recurrence rates following primary surgery range from 13 to 30% at 1–2 years, varying by definition (subjective symptoms, anatomical stage ≥ 2, or reoperation) and are influenced by patient factors (age, parity, obesity), anatomical features (prolapse stage, levator integrity), and procedural elements (compartment addressed, concomitant repairs)”
From Individualized Prediction of Recurrence Following Uterine-Preserving Pelvic Organ Prolapse Repair Using Internally Validated Machine Learning Models (2026) · cites this paper as [4]
Cites
The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction
Bump, R. C., Mattiasson, A., Bø, K., Brubaker, L. P., DeLancey, J. O. L., Klarskov, P., Shull, B. L., & Smith, A. R. B. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70243-0 · Cited by 4,275 · see citing works
Pelvic organ prolapse in the women's health initiative: Gravity and gravidity
Hendrix, S. L., Clark, A., Nygaard, I., Aragaki, A. K., Barnabei, V. M., & McTiernan, A. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.123819 · Cited by 1,273 · see citing works
Samuelsson, E. C., Víctor, F.-V., Tibblin, G., & Svärdsudd, K. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70203-6 · Cited by 699 · see citing works
Anterior colporrhaphy: A randomized trial of three surgical techniques
Weber, A. M., Walters, M. D., PIEDMONTE, M. R., & Ballard, L. A. (2001) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2001.119081 · Cited by 560 · see citing works
Pelvic organ prolapse in older women: prevalence and risk factors
Nygaard, I., Bradley, C., & Brandt, D. (2004) · Obstetrics & Gynecology · doi:10.1097/01.aog.0000136100.10818.d8 · Cited by 355 · see citing works
Hall, A. F., Theofrastous, J. P., Cundiff, G. W., Harris, R. L., Hamilton, L. F., Swift, S. E., & Bump, R. C. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70091-1 · Cited by 349 · see citing works
Risk factors for prolapse recurrence after vaginal repair
Whiteside, J. L., Weber, A. M., Meyn, L. A., & Walters, M. D. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.06.109 · Cited by 329 · see citing works
Transvaginal repair of vault prolapse: A review
Sze, E. H. M., & Karram, M. M. (1997) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(96)00337-7 · Cited by 285 · see citing works
Treatment of stress urinary incontinence due to paravaginal fascial defect.
Ac, R., Pb, E., & Nl, W. (1981) · PubMed · Cited by 269 · see citing works
DELANCEY, J. (1998) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(97)00682-0 · Cited by 224 · see citing works
Reproductive factors, family history, occupation and risk of urogenital prolapse
Chiaffarino, F., Chatenoud, L., Dindelli, M., Meschìa, M., Buonaguidi, A., Amicarelli, F., Surace, M., Bertola, E. F., Cintio, E. D., & Parazzini, F. (1999) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(98)00175-4 · Cited by 206 · see citing works
Case–Control Study of Etiologic Factors in the Development of Severe Pelvic Organ Prolapse
Swift, S., Pound, T., & Dias, J. K. (2001) · International Urogynecology Journal · doi:10.1007/s001920170062 · Cited by 172 · see citing works
Levator contraction strength and genital hiatus as risk factors for recurrent pelvic organ prolapse
Vakili, B., Zheng, Y. T., Loesch, H., Echols, K. T., Franco, N., & Chesson, R. R. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.11.022 · Cited by 131 · see citing works
Obstetric risk factors for symptomatic prolapse: A population-based approach
Tegerstedt, G., Miedel, A., Mæhle-Schmidt, M., Nyrén, O., & Hammarström, M. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.06.086 · Cited by 127 · see citing works
Nieminen, K., Huhtala, H., & Heinonen, P. K. (2003) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2003.00137.x · Cited by 102 · see citing works
Pelvic Organ Prolapse in Nulliparous Women and Their Parous Sisters
Buchsbaum, G. M., Duecy, E. E., Kerr, L. A., Huang, L., Perevich, M., & Guzick, D. S. (2006) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000245784.31082.ed · Cited by 94 · see citing works
Operation for pelvic organ prolapse: a follow-up study
Tegerstedt, G., & Hammarström, M. (2004) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/j.0001-6349.2004.00468.x · Cited by 42 · see citing works
Auwad, W., Bombieri, L., Adekanmi, O. A., Waterfield, M. R., & Freeman, R. M. (2005) · International Urogynecology Journal · doi:10.1007/s00192-005-0024-3 · Cited by 28 · see citing works
Persistent Site-Specific Defects after Reconstructive Pelvic Surgery
Larrieux, J.-R., Noel, J. W., Vragovic, O., & Scotti, R. J. (2001) · International Urogynecology Journal · doi:10.1007/s001920170056 · Cited by 3 · see citing works
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Chronic Constipation: An Evidence-Based Review
Leung, L., Riutta, T., Kotecha, J., & Rosser, W. W. (2011) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2011.04.100272 · Cited by 304 · see citing works
Risk factors for prolapse recurrence: systematic review and meta-analysis
Friedman, T., Eslick, G. D., & Dietz, H. P. (2018) · International Urogynecology Journal · doi:10.1007/s00192-017-3475-4 · Cited by 222 · see citing works
Weemhoff, M., Vergeldt, T. F. M., Notten, K., Serroyen, J., Kampschoer, P. H. N. M., & Roumen, F. J. M. E. (2012) · International Urogynecology Journal · doi:10.1007/s00192-011-1524-y · Cited by 137 · see citing works
A systematic review of clinical studies on hereditary factors in pelvic organ prolapse
Lince, S. L., van Kempen, L. C. L. T., Vierhout, M. E., & Kluivers, K. B. (2012) · International Urogynecology Journal · doi:10.1007/s00192-012-1704-4 · Cited by 107 · see citing works
Rodrigo, N., Wong, V., Shek, K. L., Martin, A. J., & Dietz, H. P. (2014) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12171 · Cited by 84 · see citing works
Complex pelvic floor failure and associated problems
Elneil, S. (2009) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2009.04.011 · Cited by 57 · see citing works
Jung, Y. W., Pak, H., Lee, I., & Kim, E. H. (2018) · Yonsei Medical Journal · doi:10.3349/ymj.2018.59.4.539 · Cited by 43 · see citing works
Family history and pelvic organ prolapse: a systematic review and meta-analysis
Samimi, P., Jones, S. H., & Giri, A. (2021) · International Urogynecology Journal · doi:10.1007/s00192-020-04559-z · Cited by 42 · see citing works
Mesh in prolapse surgery: an imaging perspective
Dietz, H. P. (2012) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.12272 · Cited by 38 · see citing works
Shek, K. L., & Dietz, H. P. (2014) · Australasian Journal of Ultrasound in Medicine · doi:10.1002/j.2205-0140.2014.tb00108.x · Cited by 28 · see citing works
Risk factors for recurrence of genital prolapse
Salvatore, S., Siesto, G., & Serati, M. (2010) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e32833e4974 · Cited by 26 · see citing works
Clinical consequences of levator trauma
Dietz, H. P. (2012) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.11141 · Cited by 25 · see citing works
The natural history of cystocele recurrence
Dietz, H. P., Hankins, K. J., & Wong, V. (2014) · International Urogynecology Journal · doi:10.1007/s00192-014-2339-4 · Cited by 22 · see citing works
Surgical decision making for symptomatic pelvic organ prolapse: evidence-based approach
Jeon, M. J. (2019) · Obstetrics & Gynecology Science · doi:10.5468/ogs.2019.62.5.307 · Cited by 19 · see citing works
Self-citationKayondo, M., Geissbüehler, V., Migisha, R., Kajabwangu, R., Njagi, J., Kato, P. K., Fajardo, Y., Lugobe, H. M., & Kaye, D. K. (2022) · International Urogynecology Journal · doi:10.1007/s00192-021-04930-8 · Cited by 15 · see citing works
Midterm prospective comparison of vaginal repair with mesh vs Prolift system devices for prolapse
Chen, Y., Cao, Q., Ding, J., Hu, C., Feng, W., & Hua, K. (2012) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2012.06.015 · Cited by 12 · see citing works
The mesh debate: Transvaginal anterior anchored mesh should not be abandoned
Wong, V., & Shek, K. L. (2017) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12589 · Cited by 10 · see citing works
Value of pelvic examination in women with pelvic organ prolapse: A systematic review
Pizzoferrato, A., Sallée, C., Thubert, T., Fauconnier, A., & Deffieux, X. (2024) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.15697 · Cited by 8 · see citing works
Costa, J., Towobola, B., McDowel, C., & Ashe, R. G. (2014) · Europe PMC (PubMed Central) · Cited by 8 · see citing works
Nyyssönen, V., Talvensaari‐Mattila, A., & Santala, M. (2013) · ISRN Obstetrics and Gynecology · doi:10.1155/2013/958670 · Cited by 7 · see citing works
Operative Therapie der weiblichen Inkontinenz
Zugor, V., Akbarov, I., Karapanos, L., & Heidenreich, A. (2018) · Aktuelle Urologie · doi:10.1055/s-0043-121479 · Cited by 7 · see citing works
Minimally invasive surgery in pelvic floor repair
Zwain, O., Aoun, J., & Eisenstein, D. (2017) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000377 · Cited by 5 · see citing works
UVA-Photoactivated Riboflavin Treatment of Vaginal Cells Derived from Pelvic Organ Prolapse Cases
Schultz, K. J., Siddighi, S., Hardesty, J. S., Waggonner, D. B., Yune, J. J., & Chan, P. J. (2014) · Gynecologic and Obstetric Investigation · doi:10.1159/000357617 · Cited by 4 · see citing works
Jeon, M. J., Suh, D. H., Kim, C. H., Cho, H.-H., Shin, J.-H., Lee, S. R., Jung, Y. W., Kim, S. R., & Kong, M. K. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-034218 · Cited by 3 · see citing works
Self-citationWhat's wrong with the debate on mesh surgery?
Dietz, H. P. (2012) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/j.1479-828x.2012.01467.x · Cited by 3 · see citing works
Guanzon, A., HEIT, M. H., & Khoder, W. (2017) · Urogynecology · doi:10.1097/spv.0000000000000474 · Cited by 3 · see citing works
Mesh implants in incontinence and prolapse surgery: an ultrasound perspective
Dietz, H. P. (2012) · Expert Review of Obstetrics & Gynecology · doi:10.1586/eog.12.76 · Cited by 3 · see citing works
Diagnóstico y manejo del prolapso de órganos pélvicos, presente y futuro
Dietz, H. P., & Rojas, R. G. (2013) · Revista Médica Clínica Las Condes · doi:10.1016/s0716-8640(13)70152-4 · Cited by 3 · see citing works
Study of correlation between symptoms and signs in women with anterior vaginal wall prolapse
Bijwe, S. A., & Rajbhara, P. (2017) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20172953 · Cited by 1 · see citing works
İlhan, T. T. (2016) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2016/18360.8104 · Cited by 1 · see citing works
Banakhevych, R. M., Акимова, К. Б., Гриценко, П. О., & Roghnev, E. Y. (2014) · Medicni perspektivi · doi:10.26641/2307-0404.2014.2.28332 · Cited by 1 · see citing works
Prevention of complications after surgical treatment of colpocystocele.
Banakhevych, R. M., Акимова, К. Б., & Pariienko, K. (2018) · Medicni perspektivi · doi:10.26641/2307-0404.2018.2.133944 · Cited by 1 · see citing works
Malul, S., Chill, H. H., Yosef, R., Miron-Shatz, T., & Shveiky, D. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15166366
Influence of anesthesia techniques of caesarean section on memory, perception and speech.
Volkov, O. (2014) · Medicni perspektivi · doi:10.26641/2307-0404.2014.2.28333
Crafoord, K. (2009) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Jung, Y. S., Kim, S. R., Moon, Y. J., Kim, S. K., & Bai, S. W. (2012) · Korean Journal of Obstetrics & Gynecology · doi:10.5468/kjog.2012.55.8.564
Self-citationExplorations of pelvic floor ultrasound
Weemhoff, M. (2013) · doi:10.26481/dis.20130705mw
Meutia, A. P., & Triyarintana, A. (2020) · Journal of Gynecologic Surgery · doi:10.1089/gyn.2020.0010 · Cited by 1 · see citing works
Cho, M. K. (2026) · Chonnam Medical Journal · doi:10.4068/cmj.2026.62.1.37
- Authors
- Jeon, M. J., Chung, S. M., Jung, H. J., Kim, S. K., & Bai, S. W.
- Affiliations
- Yonsei University (KR)
- Venue
- Gynecologic and Obstetric Investigation
- Publisher
- S. Karger AG
- Published
- 2008
- Volume
- 66
- Issue
- 4
- Pages
- 268-273
- ISSN
- 0378-7346 (ISSN-L)
- 1423-002X
- OpenAlex
- W1968957316
- Cited by
- 40
- References
- 19
- Citations by year
- 2026: 2 · 2024: 1 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 5 · 2016: 1 · 2014: 7 · 2013: 3 · 2012: 7
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Gynecologic and Obstetric Investigation (publishedVersion)
- PubMed (publishedVersion)
- YUHSpace (Yonsei University Medical Library) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Surgery › Hernia repair and management
- Keywords
- pelvic organ prolapse, prolapse recurrence, risk factors, pelvic reconstruction, anterior compartment prolapse, parity, heavy lifting, chronic constipation, hormone replacement therapy
- MeSH terms
- Female, Humans, Middle Aged, Recurrence, Retrospective Studies, Risk Factors, Uterine Prolapse, Proportional Hazards Models, Kaplan-Meier Estimate
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