Aortic dilatation in Turner syndrome: the role of MRI in early recognition
Abstract
Background Aortic dilatation and dissection are rare but important complications of Turner syndrome that increase the risk of sudden death in young patients.Objective To assess the value of aortic MRI in patients with Turner syndrome; in particular to demonstrate early aortic dilatation.Materials and methods A total of 21 patients with Turner syndrome underwent MRI of the thoracic aorta with measurement of vessel diameter at four levels.Results Measurements were normal for age in 15 cases, two patients presented with values at the upper limit of normal and four had obvious dilatation of the ascending aorta. All were symptom free.Conclusions MRI allows the non-invasive demonstration of early aortic dilatation, which may lead to earlier surgery in asymptomatic individuals.
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Dilation of the aorta, brachiocephalic and carotid arteries may be present even in the absence of structural heart disease, consistent with an underlying generalized arteriopathy.
“Dilation of the aorta, brachiocephalic and carotid arteries may be present even in the absence of structural heart disease, consistent with an underlying generalized arteriopathy.419,436,437”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [436]
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- Authors
- Chalard, F., Ferey, S., Teinturier, C., & Kalifa, G.
- Affiliations
- Hôpital Saint-Vincent-de-Paul (FR)
- Corresponding author
- Kalifa, Gabriel
- Venue
- Pediatric Radiology
- Published
- 2004-12-29
- Volume
- 35
- Issue
- 3
- Pages
- 323-326
- ISSN
- 0301-0449 (ISSN-L)
- 1432-1998
- OpenAlex
- W2052801006
- Cited by
- 40
- References
- 22
- Citations by year
- 2024: 2 · 2023: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 3 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 1 · 2013: 3 · 2012: 3
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Pediatric Radiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Disease and Treatment Approaches
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Keywords
- Turner syndrome, aortic dilatation, thoracic aorta, ascending aorta, aortic dissection, sudden death, early detection
- MeSH terms
- Adolescent, Adult, Aorta, Thoracic, Aortic Diseases, Child, Child, Preschool, Dilatation, Pathologic, Female, Humans, Magnetic Resonance Imaging, Turner Syndrome
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