Cardiovascular imaging in Turner syndrome: state-of-the-art practice across the lifespan
Open accessAbstract
Cardiovascular imaging is essential to providing excellent clinical care for girls and women with Turner syndrome (TS). Congenital and acquired cardiovascular diseases are leading causes of the lifelong increased risk of premature death in TS. Non-invasive cardiovascular imaging is crucial for timely diagnosis and treatment planning, and a systematic and targeted imaging approach should combine echocardiography, cardiovascular magnetic resonance and, in select cases, cardiac CT. In recent decades, evidence has mounted for the need to perform cardiovascular imaging in all females with TS irrespective of karyotype and phenotype. This is due to the high incidence of outcome-determining lesions that often remain subclinical and occur in patterns specific to TS. This review provides an overview of state-of-the-art cardiovascular imaging practice in TS, by means of a review of the most recent literature, in the context of a recent consensus statement that has highlighted the role of cardiovascular diseases in these females.
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The principal non-invasive imaging modalities are TTE, CMR, and CT.
“The principal non-invasive imaging modalities are TTE, CMR, and CT.425”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [425]
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Clinical practice guidelines for the care of girls and women with Turner syndrome.
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- Authors
- Mortensen, K. H., Young, L., De Backer, J., Silberbach, M., Collins, R. T., Duijnhouwer, A. L., Pandya, B., Gravholt, C. H., Lopez, L., & Roos-Hesselink, J. W.
- Affiliations
- Great Ormond Street Hospital (GB)
- Seattle Children's Hospital (US)
- Department of Cardiology and Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium
- Oregon Health & Science University (US)
- Stanford Medicine (US)
- Radboud University Medical Center (NL)
- National Health Service (GB)
- Aarhus University Hospital (DK)
- Florida International University (US)
- Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
- Corresponding author
- Mortensen, Kristian H
- ORCID
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2018-09-18
- Volume
- 104
- Issue
- 22
- Pages
- 1823-1831
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- OpenAlex
- W2892296304
- Cited by
- 35
- References
- 50
- Citations by year
- 2025: 3 · 2024: 6 · 2023: 4 · 2022: 2 · 2021: 8 · 2020: 4 · 2019: 6 · 2018: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Heart (publishedVersion)
- PubMed (publishedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- Novo Nordisk Fonden (NNF13OC0003234, NNF15OC0016474)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- Turner syndrome, cardiovascular imaging, congenital heart disease, acquired cardiovascular disease, echocardiography, cardiovascular magnetic resonance, cardiac CT, premature mortality, karyotype, consensus statement
- MeSH terms
- Adolescent, Adult, Age Factors, Aortic Dissection, Aortic Aneurysm, Cardiovascular Diseases, Cause of Death, Female, Heart Defects, Congenital, Heart Valve Diseases, Humans, Middle Aged, Predictive Value of Tests, Prognosis, Risk Factors, Turner Syndrome, Comorbidity, Prevalence, Young Adult, Cardiac Imaging Techniques
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