The negative impact of attention-deficit/hyperactivity disorder on occupational health in adults and adolescents
Abstract
Purpose To review the negative effects of attention-deficit/hyperactivity disorder (ADHD) in adolescence and adulthood on work productivity and occupational health. Methods A review of the MEDLINE database was carried out to identify direct and indirect effects of ADHD on work, employment and occupational health. Results ADHD is associated with higher levels of unemployment versus controls. Adults with ADHD who are employed experience workplace impairment and reduced productivity, as well as behavioural issues such as irritability and low frustration tolerance. Adults with ADHD are also at increased risk of accidents, trauma and workplace injuries, particularly traffic accidents. Indirect effects of ADHD on occupational health include reduced educational achievement and increased rates of substance abuse and criminality. Overall, ADHD in adults has a substantial economic impact as a result of absenteeism and lost productivity. Psychoeducation, combined with stimulant medications if necessary, is recommended as first-line treatment for adults with ADHD. Limited data available suggest that stimulant treatment can improve work productivity and efficacy, and reduce the risks associated with driving, although further studies are necessary. Conclusions ADHD can affect the ability to gain and maintain employment and to work safely and productively. As ADHD is a treatable condition, patients, employers and physicians have a role to play in ensuring optimal occupational health.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Adult ADHD is associated with substantial impairments in productive role functioning, social role functioning, and most strongly in cognitive functioning.
“Our results regarding role impairments are also consistent with much previous research in showing that adult ADHD is associated with substantial impairments in productive role functioning (Kupper et al. 2012), social role functioning (Bouchard and Saint-Aubin 2014), and most strongly in cognitive functioning (Ivanchak et al. 2012)”
From The descriptive epidemiology of DSM-IV adult ADHD in the world health organization world mental health surveys (2017) · cites this paper as Kupper et al. 2012
Cites
Biederman, J. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.816 · Cited by 1,498 · see citing works
Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder
Fayyad, J., De Graaf, R., Kessler, R., Alonso, J., Angermeyer, M., Demyttenaere, K., De Girolamo, G., Haro, J. M., Karam, E. G., Lara, C., et al. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.034389 · Cited by 1,321 · see citing works
Kooij, S. J., Bejerot, S., Blackwell, A., Caci, H., Casas-Brugué, M., Carpentier, P. J., Edvinsson, D., Fayyad, J., Foeken, K., Fitzgerald, M., et al. (2010) · BMC Psychiatry · doi:10.1186/1471-244x-10-67 · Cited by 928 · see citing works
Self-citationAttention deficit hyperactivity disorder adults: Comorbidities and adaptive impairments
Murphy, K., & Barkley, R. A. (1996) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(96)90022-x · Cited by 700 · see citing works
Kessler, R. C., Adler, L. A., Barkley, R., Biederman, J., Conners, C. K., Faraone, S. V., Greenhill, L. L., Jaeger, S., Secnik, K., Spencer, T., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.001 · Cited by 663 · see citing works
Barkley, R. A., & Murphy, K. R. (2010) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acq014 · Cited by 468 · see citing works
Barkley, R. A., & Fischer, M. (2011) · Developmental Neuropsychology · doi:10.1080/87565641.2010.549877 · Cited by 413 · cited 1× · see citing works
“Adults with ADHD also experience deficits of executive functioning, which can contribute to impairments in daily life (Barkley and Fischer 2011; Barkley and Murphy 2010).”
BackgroundFaraone, S. V., & Glatt, S. J. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04902pur · Cited by 387 · see citing works
Kessler, R. C., Green, J. G., Adler, L. A., Barkley, R. A., Chatterji, S., Faraone, S. V., Finkelman, M., Greenhill, L. L., Gruber, M. J., Jewell, M., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.146 · Cited by 317 · see citing works
Yen, J.-Y., Yen, C.-F., Chen, C.-S., Tang, T.-C., & Ko, C.-H. (2009) · CyberPsychology & Behavior · doi:10.1089/cpb.2008.0113 · Cited by 297 · see citing works
Nutt, D. J., Fone, K., Asherson, P., Bramble, D., Hill, P., Matthews, K., Morris, K. A., Santosh, P., Sonuga-Barke, E., Taylor, E., et al. (2007) · Journal of Psychopharmacology · doi:10.1177/0269881106073219 · Cited by 259 · see citing works
Comorbidities and Costs of Adult Patients Diagnosed with Attention-Deficit Hyperactivity Disorder
Secnik, K., Swensen, A., & Lage, M. J. (2005) · PharmacoEconomics · doi:10.2165/00019053-200523010-00008 · Cited by 247 · see citing works
Biederman, J., Monuteaux, M. C., Spencer, T., Wilens, T. E., MacPherson, H. A., & Faraone, S. V. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07091486 · Cited by 239 · see citing works
Skirrow, C., McLoughlin, G., Kuntsi, J., & Asherson, P. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.2 · Cited by 217 · cited 1× · see citing works
“In addition to symptoms of inattention, hyperactivity and impulsivity, adults with ADHD often experience mood instability in the form of irritability, volatility, swift changes in mood, hot temper and low frustration tolerance (Skirrow et al. 2009; Surman et al. 2011).”
BackgroundCastells, X., Ramos-Quiroga, J. A., Rigau, D., Bosch, R., Nogueira, M., Vidal, X., & Casas, M. (2011) · CNS Drugs · doi:10.2165/11539440-000000000-00000 · Cited by 197 · see citing works
Self-citationSULLIVAN, M. A., & RUDNIK‐LEVIN, F. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb05783.x · Cited by 172 · see citing works
Biederman, J., Petty, C. R., Fried, R., Kaiser, R., Dolan, C. R., Schoenfeld, S., Doyle, A. E., Seidman, L. J., & Faraone, S. V. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0803 · Cited by 156 · see citing works
Wigal, T., Brams, M., Gasior, M., Gao, J., Squires, L., Giblin, J., & 316 Study Group (2010) · Behavioral and Brain Functions · doi:10.1186/1744-9081-6-34 · Cited by 136 · cited 2× · see citing works
“…cross-over study of lisdexamfetamine in 127 adults with ADHD in a simulated work environment, treatment significantly improved work performance (using the Permanent Product Measure of Performance) and maintained improvements throughout the day from 2 to 4 h after dosing (Wigal et al. 2010).”
BackgroundMethodSurman, C. B. H., Biederman, J., Spencer, T., Yorks, D., Miller, C. A., Petty, C. R., & Faraone, S. V. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10081172 · Cited by 135 · cited 1× · see citing works
“In addition to symptoms of inattention, hyperactivity and impulsivity, adults with ADHD often experience mood instability in the form of irritability, volatility, swift changes in mood, hot temper and low frustration tolerance (Skirrow et al. 2009; Surman et al. 2011).”
BackgroundCox, D. J., Merkel, R. L., Penberthy, J. K., Kovatchev, B., & Hankin, C. S. (2004) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200403000-00007 · Cited by 120 · see citing works
Cigarette smoking associated with attention deficit hyperactivity disorder
Wilens, T. E., Vitulano, M., Upadhyaya, H., Adamson, J., Sawtelle, R., Utzinger, L., & Biederman, J. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2008.04.030 · Cited by 103 · see citing works
Cox, D. J., Merkel, R. L., Moore, M., Thorndike, F., Muller, C., & Kovatchev, B. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2947 · Cited by 95 · see citing works
Watson, M. S., Lloyd-Puryear, M. A., Mann, M. Y., Rinaldo, P., & Howell, R. R. (2006) · Genetics in Medicine · doi:10.1097/01.gim.0000223467.60151.02 · Cited by 93 · see citing works
Trauma and adult attention deficit hyperactivity disorder
Kaya, A., Taner, Y., Guclu, B., Taner, E., Kaya, Y., Bahcivan, H., & Benli, I. (2008) · Journal of International Medical Research · doi:10.1177/147323000803600102 · Cited by 63 · see citing works
Attention-Deficit/Hyperactivity Disorder in Adults: Evidence-Based Recommendations for Management
Rostain, A. L. (2008) · Postgraduate Medicine · doi:10.3810/pgm.2008.09.1905 · Cited by 50 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Collaborators, O. B. O. T. W. W. M. H. S., Fayyad, J., Sampson, N. A., Hwang, I., Adamowski, T., Aguilar-Gaxiola, S., Al-Hamzawi, A., Andrade, L. H. S. G., Borges, G., de Girolamo, G., et al. (2017) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-016-0208-3 · Cited by 824 · see citing works
Shared genetic background between children and adults with attention deficit/hyperactivity disorder
Rovira, P., Demontis, D., Sánchez-Mora, C., Zayats, T., Klein, M., Mota, N. R., Weber, H., Garcia-Martínez, I., Pagerols, M., Vilar-Ribó, L., et al. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0664-5 · Cited by 111 · see citing works
Self-citationMcGowan, N. M., Voinescu, B. I., & Coogan, A. N. (2016) · Chronobiology International · doi:10.1080/07420528.2016.1208214 · Cited by 59 · see citing works
Adler, L. A., Dirks, B., Deas, P., Raychaudhuri, A., Dauphin, M., Saylor, K., & Weisler, R. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-253 · Cited by 45 · see citing works
Lauder, K., McDowall, A., & Tenenbaum, H. R. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.893469 · Cited by 36 · see citing works
Adult attention deficit hyperactivity disorder and early maladaptive schemas
Kiraz, S., & Sertçelik, S. (2021) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2569 · Cited by 20 · see citing works
Murphy, D., Glaser, K., Hayward, H., Eklund, H., Cadman, T., Findon, J., Woodhouse, E., Ashwood, K., Beecham, J., Bolton, P., et al. (2018) · Programme Grants for Applied Research · doi:10.3310/pgfar06020 · Cited by 18 · see citing works
Hoarding symptoms and workplace impairment
Mathes, B. M., Henry, A., Schmidt, N. B., & Norberg, M. M. (2019) · British Journal of Clinical Psychology · doi:10.1111/bjc.12212 · Cited by 15 · see citing works
Baby, M., Priya, V., Pallavi, J., Karthik Chand, B., Srinivasan, L., Rana, S., Tawil, S., Haque, S., Ghosh, P., Bhattacharya, P., et al. (2025) · International Journal of Women's Health · doi:10.2147/ijwh.s511297 · Cited by 2 · see citing works
- Authors
- Küpper, T., Haavik, J., Drexler, H., Ramos-Quiroga, J. A., Wermelskirchen, D., Prutz, C., & Schauble, B.
- Affiliations
- RWTH Aachen University (DE)
- University of Bergen (NO)
- Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin (DE)
- Janssen (Germany) (DE)
- Corresponding author
- Küpper, Thomas
- Venue
- International Archives of Occupational and Environmental Health
- Published
- 2012-07-03
- Volume
- 85
- Issue
- 8
- Pages
- 837-847
- ISSN
- 0340-0131 (ISSN-L)
- 1432-1246
- OpenAlex
- W2070716977
- Cited by
- 152
- References
- 25
- Citations by year
- 2026: 14 · 2025: 11 · 2024: 6 · 2023: 17 · 2022: 5 · 2021: 11 · 2020: 7 · 2019: 13 · 2018: 15 · 2017: 9 · 2016: 16 · 2015: 9 · 2014: 12 · 2013: 6 · 2012: 1
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Archives of Occupational and Environmental Health (publishedVersion)
- PubMed (publishedVersion)
- RWTH Publications (RWTH Aachen) (submittedVersion)
- Funders
- Eli Lilly and Company
- Fundación Alicia Koplowitz
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Health Professions › General Health Professions › Workplace Health and Well-being
- Social Sciences › Safety Research › Disability Education and Employment
- Keywords
- attention deficit hyperactivity disorder, occupational health, labor productivity, unemployment, occupational injuries, traffic accidents, absenteeism, economic burden, stimulant medication, psychoeducation, adolescents, adults, substance abuse, criminality
- MeSH terms
- Accidents, Traffic, Adolescent, Adult, Attention Deficit Disorder with Hyperactivity, Crime, Educational Status, Efficiency, Humans, Irritable Mood, Unemployment, Occupational Health, Substance-Related Disorders, Occupational Injuries
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review