Neck cooling and cognitive performance following exercise-induced hyperthermia.
Abstract
Purpose To assess the efficacy of neck cooling on cognitive performance following exertional hyperthermia.Methods Twelve healthy men completed two experimental trials [control (CON) and neck cooling collar (NCC)] in a counter-balanced design. They ran on a treadmill at 70% VO2peak under warm and humid conditions (dry bulb temperature: 30.2 ± 0.3 °C, relative humidity: 71 ± 2 %) for 75 min or until volitional exhaustion. Gastrointestinal, neck and skin temperatures, heart rate and subjective ratings were assessed. Serum brain-derived neurotrophic factor (BDNF) levels were measured before and after each run. Cognitive performance comprising symbol digit matching, search and memory, digit span, choice reaction time and psychomotor vigilance test (PVT) were assessed before and after exercise.Results Mean gastrointestinal temperature was similar after exercise between trials (CON: 39.5 ± 0.4 °C vs. NCC: 39.6 ± 0.3 °C; p = 0.15). Mean neck temperature was lowered in NCC compared to CON after the run (36.4 ± 1.6 °C vs. NCC: 26.0 ± 0.3 °C; p < 0.001). Exercise-induced hyperthermia improved mean reaction time in the symbol digit matching test (-134 ± 154 ms; p < 0.05) and the PVT (-18 ± 30 ms; p < 0.05). Maximum span was increased in the digit span test (1 ± 2; p < 0.05). Application of NCC reduced the number of search errors made in level 3 of the search and memory test (p < 0.05). Mean serum BDNF levels were increased following exercise-induced hyperthermia in both trials (p < 0.05).Conclusion Exercise-induced hyperthermia improves working memory and alertness. Neck cooling may only enhance performance in tasks of higher complexity.
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Relative changes in peripheral levels of blood lactate are correlated significantly with cognitive performance levels after high-intensity interval endurance exercises.
“relative changes in peripheral levels of blood lactate are correlated significantly with cognitive performance levels after high-intensity interval endurance exercises (Lee et al., 2014; Tsukamoto et al., 2016; Hashimoto et al., 2017)”
From Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research (2019) · cites this paper as Lee et al., 2014
Cites
Durnin, J. V. G. A., & Womersley, J. (1974) · British Journal Of Nutrition · doi:10.1079/bjn19740060 · Cited by 6,343 · see citing works
Exercise training increases size of hippocampus and improves memory
Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015950108 · Cited by 4,855 · see citing works
The blood–brain barrier: an overview
Ballabh, P., Braun, A., & Nedergaard, M. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2003.12.016 · Cited by 2,276 · see citing works
The Gross Composition of the Body
Siri, W. E. (1956) · Advances in biological and medical physics · doi:10.1016/b978-1-4832-3110-5.50011-x · Cited by 1,771 · see citing works
Transport of brain-derived neurotrophic factor across the blood–brain barrier
Pan, W., Banks, W. A., Fasold, M. B., Bluth, J., & Kastin, A. J. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00141-5 · Cited by 1,354 · see citing works
Evidence for a release of brain-derived neurotrophic factor from the brain during exercise
Rasmussen, P., Brassard, P., Adser, H., Pedersen, M. V., Leick, L., Hart, E., Secher, N. H., Pedersen, B. K., & Pilegaard, H. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.048512 · Cited by 914 · see citing works
Gur, R. C., Turetsky, B. I., Matsui, M., Yan, M., Bilker, W., Hughett, P., & Gur, R. E. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-10-04065.1999 · Cited by 909 · see citing works
FERRIS, L. T., WILLIAMS, J. S., & SHEN, C.-L. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31802f04c7 · Cited by 849 · see citing works
Effects of Acute Physical Exercise Characteristics on Cognitive Performance
Brisswalter, J., Collardeau, M., & Ren, A. Y. O. (2002) · Sports Medicine · doi:10.2165/00007256-200232090-00002 · Cited by 642 · see citing works
Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males
Griffin, É. W., Mullally, S. L., Foley, C., Warmington, S. A., O’Mara, S. M., & Kelly, A. M. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.06.005 · Cited by 543 · see citing works
Effects of heat stress on cognitive performance: the current state of knowledge
Hancock, P. A., & Vasmatzidis, I. (2003) · International Journal of Hyperthermia · doi:10.1080/0265673021000054630 · Cited by 512 · see citing works
Effects of hot and cold temperature exposure on performance: a meta-analytic review
Pilcher, J. J., Nadler, E. D., & Busch, C. (2002) · Ergonomics · doi:10.1080/00140130210158419 · Cited by 504 · see citing works
Mental fatigue and task control: Planning and preparation
Lorist, M. M., Klein, M., Nieuwenhuis, S., de Jong, R., Mulder, G., & Meijman, T. F. (2000) · Psychophysiology · doi:10.1111/1469-8986.3750614 · Cited by 453 · see citing works
Effects of fluid ingestion on cognitive function after heat stress or exercise-induced dehydration
Cian, C., Barraud, P.-A., Melin, B., & Raphel, C. (2001) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(01)00142-8 · Cited by 435 · see citing works
The neuroanatomy of general intelligence: sex matters
Haier, R., Jung, R., Yeo, R., Head, K., & Alkire, M. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.019 · Cited by 395 · see citing works
Sexual dimorphism and asymmetries in the gray–white composition of the human cerebrum
Allen, J. S., Damásio, H., Grabowski, T. J., Bruss, J., & Zhang, W. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00034-x · Cited by 392 · see citing works
Gómez‐Pinilla, F., Vaynman, S., & Ying, Z. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06524.x · Cited by 379 · see citing works
Temperature regulation by hypothalamic proportional control with an adjustable set point
Hammel, H. T., Jackson, D. C., Stolwijk, J. A. J., Hardy, J. D., & Strømme, S. B. (1963) · Journal of Applied Physiology · doi:10.1152/jappl.1963.18.6.1146 · Cited by 354 · see citing works
Serum S-100β as a possible marker of blood–brain barrier disruption
Kapural, M., Križanac-Bengez, L., Barnett, G. H., Perl, J., Masaryk, T., Apollo, D., Rasmussen, P. A., Mayberg, M. R., & Janigro, D. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02586-6 · Cited by 285 · see citing works
Hyperthermia impairs short‐term memory and peripheral motor drive transmission
Racinais, S., Gaoua, N., & Grantham, J. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.157420 · Cited by 276 · see citing works
Pedersen, B. K., Pedersen, M., Krabbe, K. S., Brüünsgaard, H., Matthews, V. B., & Febbraio, M. A. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.048561 · Cited by 256 · see citing works
Cognitive Performance after Strenuous Physical Exercise
Hogervorst, E., Riedel, W., Jeukendrup, A., & Jolles, J. (1996) · Perceptual and Motor Skills · doi:10.2466/pms.1996.83.2.479 · Cited by 244 · see citing works
Alterations in cognitive performance during passive hyperthermia are task dependent
Gaoua, N., Racinais, S., Grantham, J., & El Massioui, F. (2011) · International Journal of Hyperthermia · doi:10.3109/02656736.2010.516305 · Cited by 234 · see citing works
Task performance in heat: a review
Ramsey, J. D. (1995) · Ergonomics · doi:10.1080/00140139508925092 · Cited by 181 · see citing works
Exercise and Cognitive Function
Loprinzi, P. D., & Kane, C. (2015) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2014.12.023 · Cited by 159 · see citing works
The influence of exercise-induced fatigue on cognitive function
Moore, R. D., Romine, M. W., O’Connor, P. J., & Tomporowski, P. D. (2012) · Journal of Sports Sciences · doi:10.1080/02640414.2012.675083 · Cited by 146 · see citing works
Boxing and Running Lead to a Rise in Serum Levels of S-100B Protein
Otto, M., Holthusen, S. M., Bahn, E., et al. (2000) · International Journal of Sports Medicine · doi:10.1055/s-2000-8480 · Cited by 133 · see citing works
Simmons, S. E., Saxby, B. K., McGlone, F. P., & Jones, D. A. (2008) · European Journal of Applied Physiology · doi:10.1007/s00421-008-0677-y · Cited by 124 · see citing works
Blood-brain barrier integrity may be threatened by exercise in a warm environment
Watson, P., Shirreffs, S. M., & Maughan, R. J. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00676.2004 · Cited by 110 · see citing works
Hydration effects on cognitive performance during military tasks in temperate and cold environments
Adam, G. E., Carter, R., Cheuvront, S. N., Merullo, D. J., Castellani, J. W., Lieberman, H. R., & Sawka, M. N. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.028 · Cited by 109 · see citing works
Bailey, D. M., Evans, K. A., McEneny, J., Young, I. S., Hullin, D. A., James, P. E., Ogoh, S., Ainslie, P. N., Lucchesi, C., Rockenbauer, A., et al. (2011) · Experimental Physiology · doi:10.1113/expphysiol.2011.060178 · Cited by 97 · see citing works
Effects of Dehydration and Fluid Ingestion on Cognition
Tomporowski, P. D., Beasman, K. M., Ganio, M. S., & Cureton, K. J. (2007) · International Journal of Sports Medicine · doi:10.1055/s-2007-965004 · Cited by 94 · see citing works
Cooling the Neck Region During Exercise in the Heat
Tyler, C. J., & Sunderland, C. D. (2011) · Journal of Athletic Training · doi:10.4085/1062-6050-46.1.61 · Cited by 94 · see citing works
Practical neck cooling and time-trial running performance in a hot environment
Tyler, C. J., Wild, P., & Sunderland, C. D. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1567-7 · Cited by 93 · see citing works
Increase in Serum S100B Protein Level After a Swimming Race
Dietrich, M. O., Tort, A. B. L., Schaf, D. V., et al. (2003) · Canadian Journal of Applied Physiology · doi:10.1139/h03-054 · Cited by 91 · see citing works
Ely, B. R., Sollanek, K. J., Cheuvront, S. N., Lieberman, H. R., & Kenefick, R. W. (2012) · European Journal of Applied Physiology · doi:10.1007/s00421-012-2506-6 · Cited by 85 · see citing works
Lee, M. C., Okamoto, M., Liu, Y. F., Inoue, K., Matsui, T., Nogami, H., & Soya, H. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00869.2012 · Cited by 76 · see citing works
Exercise and Cognitive Function: A Neuroendocrinological Explanation
McMorris, T. (2009) · doi:10.1002/9780470740668.ch2 · Cited by 57 · see citing works
Psychological Aspects of Military Performance in Hot Environments
Johnson, R. F., & Kobrick, J. L. (2001) · Defense Technical Information Center (DTIC) · Cited by 16 · see citing works
Hancock, P. A. (1984) · American Industrial Hygiene Association Journal · doi:10.1080/15298668491399488 · Cited by 12 · see citing works
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- Authors
- Lee, J. K. W., Koh, A. C. H., Koh, S. X. T., Liu, G. J. X., Nio, A. Q. X., & Fan, P. W. P.
- Affiliations
- DSO National Laboratories (SG)
- National University of Singapore (SG)
- Cardiff Metropolitan University (GB)
- Corresponding author
- Lee, Jason K. W.
- Venue
- European Journal of Applied Physiology
- Published
- 2013-12-07
- Volume
- 114
- Issue
- 2
- Pages
- 375-384
- ISSN
- 0020-9376 (ISSN-L)
- 1439-6319
- 1439-6327
- OpenAlex
- W2095587767
- Cited by
- 100
- References
- 40
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 6 · 2023: 9 · 2022: 11 · 2021: 7 · 2020: 9 · 2019: 10 · 2018: 13 · 2017: 7 · 2016: 10 · 2015: 4 · 2014: 2
- FWCI
- 3.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- neck cooling, exercise-induced hyperthermia, cognitive performance, brain-derived neurotrophic factor, working memory, alertness, psychomotor vigilance, reaction time, heat stress, treadmill running, gastrointestinal temperature
- MeSH terms
- Adult, Body Temperature, Cognition, Heart Rate, Humans, Hyperthermia, Induced, Hypothermia, Induced, Male, Memory, Neck, Oxygen Consumption, Psychomotor Performance, Exercise, Case-Control Studies, Brain-Derived Neurotrophic Factor
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