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Cited by 60Body Composition Measurement TechniquesBone health and osteoporosis researchHIV-related health complications and treatments

Validation of a dual energy X-ray absorptiometer: measurement of bone mass and soft tissue composition

Madsen, Ole Rintek, Jensen, Jens-Erik Beck, S�rensen, Ole Helmer·1997·European Journal of Applied Physiology
DOI 10.1007/s004210050204
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Abstract

We investigated the reproducibility of total and regional body composition measurements performed on a dual energy X-ray absorptiometer (DXA). A group of 58 women aged 21-81 (mean 52.4) years was scanned twice with repositioning to determine intraobserver reproducibility of measurements of bone mineral density (BMD, g.cm-2), bone mineral content (BMC, g), lean mass (LM, kg) and fat mass (FM, kg) of the total body and of the major subregions of the body. In addition, the ability of the DXA machine to detect changes in LM and FM (simulated by placing 11.1 and 22.3 kg porcine lard on the body of 11 subjects) was examined. Coefficients of variations calculated from the root mean square averages of individual standard deviations were as follows (BMD, BMC, LM, FM) [corrected]: 1.4%, 1.1%, 1.4%, 1.7% (total body), 2.2%, 2.1%,-,- (head), 2.8%, 2.8%, 2.0%, 2.2% (trunk), 3.6%, 3.9%, 4.0%, 4.9% (arms), 2.7%, 1.3%, 2.6%, 2.8% (legs). Percentage fat (%fat) of exogenous lard was 81.3 (SD 3.5)% as assessed by the absorptiometer which corresponded well with the result of chemical analysis (82.8%). Estimated %fat of exogenous lard was not influenced by initial body mass or percentage body fat. Percentages of expected mean values with 11.1 kg lard placed on the body were 99.9 (SD 0.3) for body mass, 100.5 (SD 2.1) for LM, and 99.5 (SD 3.5) for FM. BMD was overestimated by 3.2% (P < 0.005) with 11.1 kg lard on the body. BMD as well as BMC increased significantly with 22.3 kg lard on the body (P < 0.005). The results showed that BMD, BMC, LM, and FM of the total body were precisely estimated by the DXA machine used. Regional measurements were less precise. Changes in total body soft tissue composition were precisely and accurately estimated. The lard placed on the body falsely affected BMD and BMC measurements. Changes in body mass could have a similar effect.

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  • Sleeve gastrectomy produces weight loss between that of purely restrictive and malabsorptive procedures.

    “Sleeve gastrectomy is becoming increasingly common, with weight loss falling between the purely restrictive and malabsorptive procedures (1 to 2 year weight loss: 20-30%; excess BMI loss: 45-80%).36, 46-50.”

    From Bone loss after bariatric surgery: causes, consequences, and management (2014) · cites this paper as [36]

  • After gastric banding, patients typically lose 20-30% of initial body weight and 41-54% of excess body weight.

    “After GB, patients typically lose 20-30% of initial body weight and 41-54% of excess body weight36, 37.”

    From Bone loss after bariatric surgery: causes, consequences, and management (2014) · cites this paper as [36]

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Authors
Madsen, O. R., Jensen, J.-E. B., & S�rensen, O. H.
Affiliations
University of Copenhagen (DK)
ORCID
Venue
European Journal of Applied Physiology
Publisher
Springer Science and Business Media LLC
Published
1997-05-01
Volume
75
Issue
6
Pages
554-558
ISSN
  • 0020-9376 (ISSN-L)
  • 1439-6319
  • 1439-6327
DOI
10.1007/s004210050204
OpenAlex
W2021767918
Cited by
60
References
13
Citations by year
2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2019: 2 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 6 · 2013: 3 · 2012: 5
FWCI
1.22
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • European Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
  • Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
Keywords
dual-energy X-ray absorptiometry, measurement reproducibility, bone mineral density, bone mineral content, lean body mass, fat mass, body composition, soft tissue composition, fat detection, regional body composition, women, body mass index, body fat percentage, measurement error, coefficient of variation, body fat distribution
MeSH terms
Adipose Tissue, Adult, Aged, Body Composition, Dietary Fats, Female, Humans, Middle Aged, Reproducibility of Results, Absorptiometry, Photon, Bone Density

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