Mutation spectrum and splicing variants in the OPA1 gene

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OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

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OPA1 requires mitofusin 1 to promote mitochondrial fusion

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Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

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Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

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The i -AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

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Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation

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Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function

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Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models

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Mitochondrial fission and fusion

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Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy

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Dominant optic atrophy and leber’s hereditary optic neuropathy: update on clinical features and current therapeutic approaches.

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SARM1 loss protects retinal ganglion cells in a mouse model of autosomal dominant optic atrophy

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