Mitochondrial fission and fusion

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Chen, H., Detmer, S. A., Ewald, A. J., Griffin, E. E., Fraser, S. E., & Chan, D. C. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211046 · Cited by 2,601 · see citing works

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

de Brito, O. M., & Scorrano, L. (2008) · Nature · doi:10.1038/nature07534 · Cited by 2,442 · see citing works

Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

Sanyal, A. J., Campbell–Sargent, C., Mirshahi, F., Rizzo, W. B., Contos, M. J., Sterling, R. K., Luketic, V. A., Shiffman, M. L., & Clore, J. N. (2001) · Gastroenterology · doi:10.1053/gast.2001.23256 · Cited by 2,078 · see citing works

ER Tubules Mark Sites of Mitochondrial Division

Friedman, J. R., Lackner, L. L., West, M., DiBenedetto, J. R., Nunnari, J., & Voeltz, G. K. (2011) · Science · doi:10.1126/science.1207385 · Cited by 2,072 · see citing works

OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

Frezza, C., Cipolat, S., Martins de Brito, O., Micaroni, M., Beznoussenko, G. V., Rudka, T., Bartoli, D., Polishuck, R. S., Danial, N. N., De Strooper, B., et al. (2006) · Cell · doi:10.1016/j.cell.2006.06.025 · Cited by 1,673 · see citing works

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

Züchner, S., Mersiyanova, I. V., Muglia, M., Bissar-Tadmouri, N., Rochelle, J., Dadali, E. L., Zappia, M., Nelis, E., Patitucci, A., Senderek, J., et al. (2004) · Nature Genetics · doi:10.1038/ng1341 · Cited by 1,572 · see citing works

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

Delettre, C., Lenaers, G., Griffoin, J.-M., Gigarel, N., Lorenzo, C., Belenguer, P., Pelloquin, L., Grosgeorge, J., Turc-Carel, C., Perret, E., et al. (2000) · Nature Genetics · doi:10.1038/79936 · Cited by 1,446 · see citing works

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Alexander, C., Votruba, M., Pesch, U. E. A., Thiselton, D. L., Mayer, S., Moore, A., Rodriguez, M., Kellner, U., Leo-Kottler, B., Auburger, G., et al. (2000) · Nature Genetics · doi:10.1038/79944 · Cited by 1,330 · see citing works

Mitochondrial Dynamics and Metabolic Regulation

Wai, T., & Langer, T. (2016) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.12.001 · Cited by 1,304 · see citing works

Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency

Cogliati, S., Frezza, C., Soriano, M. E., Varanita, T., Quintana-Cabrera, R., Corrado, M., Cipolat, S., Costa, V., Casarin, A., Gomes, L. C., et al. (2013) · Cell · doi:10.1016/j.cell.2013.08.032 · Cited by 1,265 · see citing works

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

Losón, O. C., Song, Z., Chen, H., & Chan, D. C. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-10-0721 · Cited by 1,235 · see citing works

Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P., & Lenaers, G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c200677200 · Cited by 1,168 · see citing works

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

Otera, H., Wang, C., Cleland, M. M., Setoguchi, K., Yokota, S., Youle, R. J., & Mihara, K. (2010) · Journal of Cell Biology · doi:10.1083/jcb.201007152 · Cited by 1,110 · see citing works

Metabolic regulation of mitochondrial dynamics

Mishra, P., & Chan, D. C. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201511036 · Cited by 1,096 · see citing works

Dynamin, a membrane-remodelling GTPase

Ferguson, S. M., & Camilli, P. V. D. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3266 · Cited by 977 · see citing works

Structural Basis of Mitochondrial Tethering by Mitofusin Complexes

Koshiba, T., Detmer, S. A., Kaiser, J. T., Chen, H., McCaffery, J. M., & Chan, D. C. (2004) · Science · doi:10.1126/science.1099793 · Cited by 910 · see citing works

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

Ishihara, N., Fujita, Y., Oka, T., & Mihara, K. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601184 · Cited by 899 · see citing works

The Mitochondrial Protein hFis1 Regulates Mitochondrial Fission in Mammalian Cells through an Interaction with the Dynamin-Like Protein DLP1

Yoon, Y., Krueger, E. W., Oswald, B. J., & McNiven, M. A. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5409-5420.2003 · Cited by 820 · see citing works

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L

Song, Z., Chen, H., Fiket, M., Alexander, C., & Chan, D. C. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200704110 · Cited by 818 · see citing works

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

Korobova, F., Ramabhadran, V., & Higgs, H. N. (2013) · Science · doi:10.1126/science.1228360 · Cited by 817 · see citing works

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

Pernas, L. F., & Scorrano, L. (2015) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105011 · Cited by 814 · see citing works

The <i>i</i> -AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

Anand, R., Wai, T., Baker, M. J., Kladt, N., Schauss, A. C., Rugarli, E., & Langer, T. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201308006 · Cited by 812 · see citing works

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

Gandre-Babbe, S., & van der Bliek, A. M. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-12-1287 · Cited by 769 · see citing works

Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity

Ishihara, N., Eura, Y., & Mihara, K. (2004) · Journal of Cell Science · doi:10.1242/jcs.01565 · Cited by 731 · see citing works

hFis1, a Novel Component of the Mammalian Mitochondrial Fission Machinery

James, D. I., Parone, P. A., Mattenberger, Y., & Martinou, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303758200 · Cited by 653 · see citing works

MiD49 and MiD51, new components of the mitochondrial fission machinery

Palmer, C. S., Osellame, L. D., Laine, D., Koutsopoulos, O. S., Frazier, A. E., & Ryan, M. T. (2011) · The EMBO Reports · doi:10.1038/embor.2011.54 · Cited by 649 · see citing works

Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion

Song, Z., Ghochani, M., McCaffery, J. M., Frey, T. G., & Chan, D. C. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e09-03-0252 · Cited by 623 · see citing works

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

Filadi, R., Greotti, E., Turacchio, G., Luini, A., Pozzan, T., & Pizzo, P. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1504880112 · Cited by 578 · see citing works

Regulation of OPA1 processing and mitochondrial fusion by m -AAA protease isoenzymes and OMA1

Ehses, S., Lauria, I., Mancuso, G., Bernacchia, A., Geimer, S., Tondera, D., Martinou, J., Westermann, B., Rugarli, E. I., & Langer, T. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200906084 · Cited by 570 · see citing works

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

Head, B., Griparic, L., Amiri, M., Gandre-Babbe, S., & van der Bliek, A. M. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200906083 · Cited by 515 · see citing works

Mitochondrial abnormalities in non-alcoholic steatohepatitis

Caldwell, S. H., Swerdlow, R. H., Khan, E. M., Iezzoni, J. C., Hespenheide, E. E., Parks, J. K., & Parker, W. D. (1999) · Journal of Hepatology · doi:10.1016/s0168-8278(99)80033-6 · Cited by 495 · see citing works

Mitochondrial Inner-Membrane Fusion and Crista Maintenance Requires the Dynamin-Related GTPase Mgm1

Meeusen, S., DeVay, R. M., Block, J., Cassidy-Stone, A., Wayson, S. M., McCaffery, J. M., & Nunnari, J. M. (2006) · Cell · doi:10.1016/j.cell.2006.09.021 · Cited by 474 · see citing works

Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation

Mishra, P., Carelli, V., Manfredi, G., & Chan, D. C. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.03.011 · Cited by 473 · see citing works

Mitochondrial biogenesis and dynamics in the developing and diseased heart

Dorn, G. W., Vega, R. B., & Kelly, D. P. (2015) · Genes &amp; Development · doi:10.1101/gad.269894.115 · Cited by 470 · see citing works

Loss of the Intermembrane Space Protein Mgm1/OPA1 Induces Swelling and Localized Constrictions along the Lengths of Mitochondria

Griparić, L., van der Wel, N. N., Orozco, I. J., Peters, P. J., & van der Bliek, A. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400920200 · Cited by 468 · see citing works

Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage

Griparić, L., Kanazawa, T., & van der Bliek, A. M. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200704112 · Cited by 467 · see citing works

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

Santel, A., Frank, S., Gaume, B. R., Herrler, M., Youle, R. J., & Fuller, M. T. (2003) · Journal of Cell Science · doi:10.1242/jcs.00479 · Cited by 445 · see citing works

Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart

Anderson, E. J., Kypson, A. P., Rodriguez, E., Anderson, C. A., Lehr, E. J., & Neufer, P. D. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.07.031 · Cited by 440 · see citing works

The human dynamin‐related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter‐membrane space

Olichon, A., Emorine, L. J., Descoins, E., Pelloquin, L., Brichese, L., Gas, N., Guillou, E., Delettre, C., Valette, A., Hamel, C., et al. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02985-x · Cited by 430 · see citing works

Mutation spectrum and splicing variants in the OPA1 gene

Delettre, C., Griffoin, J., Kaplan, J., Dollfus, H., Lorenz, B., Faivre, L. O., Lenaers, G., Belenguer, P., & Hamel, C. (2001) · Human Genetics · doi:10.1007/s00439-001-0633-y · Cited by 398 · see citing works

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

Zhao, J., Liu, T., Jin, S., Wang, X., Qu, M., Uhlén, P., Tomilin, N., Shupliakov, O., Lendahl, U., & Nistér, M. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.198 · Cited by 370 · see citing works

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

Bertholet, A. M., Delerue, T., Millet, A. M., Moulis, M. F., David, C., Daloyau, M., Arnauné-Pelloquin, L., Davezac, N., Mils, V., Miquel, M. C., et al. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.10.011 · Cited by 363 · see citing works

Stress‐induced OMA1 activation and autocatalytic turnover regulate OPA1‐dependent mitochondrial dynamics

Baker, M. J., Lampe, P., Stojanovski, D., Korwitz, A., Anand, R., Tatsuta, T., & Langer, T. (2014) · The EMBO Journal · doi:10.1002/embj.201386474 · Cited by 346 · see citing works

A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division

Manor, U., Bartholomew, S. R., Golani, G., Christenson, E. T., Kozlov, M. M., Higgs, H. N., Spudich, J. A., & Lippincott‐Schwartz, J. (2015) · eLife · doi:10.7554/elife.08828 · Cited by 341 · see citing works

Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission

Osellame, L. D., Singh, A. P., Stroud, D. A., Palmer, C. S., Stojanovski, D., Ramachandran, R., & Ryan, M. T. (2016) · Journal of Cell Science · doi:10.1242/jcs.185165 · Cited by 336 · see citing works

Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology

Stojanovski, D., Koutsopoulos, O. S., Okamoto, K., & Ryan, M. T. (2004) · Journal of Cell Science · doi:10.1242/jcs.01058 · Cited by 332 · see citing works

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

Ji, W.-K., Hatch, A. L., Merrill, R. A., Strack, S., & Higgs, H. N. (2015) · eLife · doi:10.7554/elife.11553 · Cited by 328 · see citing works

MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death

Prudent, J., Zunino, R., Sugiura, A., Mattie, S., Shore, G. C., & McBride, H. M. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.08.001 · Cited by 321 · see citing works

Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission

Palmer, C. S., Elgass, K. D., Parton, R. G., Osellame, L. D., Stojanovski, D., & Ryan, M. T. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.479873 · Cited by 301 · see citing works

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1‐like protein

Fröhlich, C., Grabiger, S., Schwefel, D., Faelber, K., Rosenbaum, E., Mears, J. A., Rocks, O., & Daumke, O. (2013) · EMBO Journal · doi:10.1038/emboj.2013.74 · Cited by 290 · see citing works

Mammalian Dynamin-like Protein DLP1 Tubulates Membranes

Yoon, Y., Pitts, K. R., & McNiven, M. A. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.9.2894 · Cited by 285 · see citing works

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

DeVay, R. M., Domínguez‐Ramírez, L., Lackner, L. L., Hoppins, S. C., Stahlberg, H., & Nunnari, J. M. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200906098 · Cited by 276 · see citing works

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

Quirós, P. M., Ramsay, A. J., Sala, D., Fernández‐Vizarra, E., Rodríguez, F., Peinado, J. R., Fernández‐García, M. S., Vega, J. A., Enríquez, J. A., Zorzano, A., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.70 · Cited by 269 · see citing works

Increased Myocardial Oxygen Consumption Reduces Cardiac Efficiency in Diabetic Mice

How, O.-J., Aasum, E., Severson, D. L., Chan, W. Y. A., Essop, M. F., & Larsen, T. S. (2006) · Diabetes · doi:10.2337/diabetes.55.02.06.db05-1164 · Cited by 248 · see citing works

A Role for Myosin II in Mammalian Mitochondrial Fission

Korobova, F. V., Gauvin, T. J., & Higgs, H. N. (2014) · Current Biology · doi:10.1016/j.cub.2013.12.032 · Cited by 244 · see citing works

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Otera, H., Miyata, N., Kuge, O., & Mihara, K. (2016) · Journal of Cell Biology · doi:10.1083/jcb.201508099 · Cited by 229 · see citing works

OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis

Olichon, A., Elachouri, G., Baricault, L., Delettre, C., Belenguer, P., & Lenaers, G. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402048 · Cited by 228 · see citing works

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study

Cosson, P., Marchetti, A., Ravazzola, M., & Orci, L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046293 · Cited by 226 · see citing works

A bacterial dynamin-like protein

Low, H. H., & Löwe, J. (2006) · Nature · doi:10.1038/nature05312 · Cited by 223 · see citing works

OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation

Ban, T., Heymann, J. A. W., Song, Z., Hinshaw, J. E., & Chan, D. C. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq088 · Cited by 222 · see citing works

Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission

Li, S., Xu, S., Roelofs, B. A., Boyman, L., Lederer, W. J., Sesaki, H., & Karbowski, M. (2014) · The Journal of Cell Biology · doi:10.1083/jcb.201404050 · Cited by 210 · see citing works

Mutations in Fis1 disrupt orderly disposal of defective mitochondria

Shen, Q., Yamano, K., Head, B. P., Kawajiri, S., Cheung, J. T. M., Wang, C., Cho, J.-H., Hattori, N., Youle, R. J., & van der Bliek, A. M. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-09-0525 · Cited by 209 · see citing works

Constriction and Dnm1p Recruitment Are Distinct Processes in Mitochondrial Fission

Legesse-Miller, A., Massol, R., & Kirchhausen, T. L. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-10-0657 · Cited by 197 · see citing works

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

Koirala, S., Guo, Q., Kalia, R., Bui, H., Eckert, D. M., Frost, A. S., & Shaw, J. M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300855110 · Cited by 191 · see citing works

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

Liu, R., & Chan, D. C. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-08-0591 · Cited by 184 · see citing works

A Novel Dynamin-like Protein Associates with Cytoplasmic Vesicles and Tubules of the Endoplasmic Reticulum in Mammalian Cells

Yoon, Y., Pitts, K. R., Dahan, S., & McNiven, M. A. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.4.779 · Cited by 183 · see citing works

Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a Mechanism For Assembly and Membrane Curving

Low, H. H., Sachse, C., Amos, L., & Löwe, J. (2009) · Cell · doi:10.1016/j.cell.2009.11.003 · Cited by 176 · see citing works

Mitofusin‐2 knockdown increases ER –mitochondria contact and decreases amyloid β‐peptide production

Leal, N. S., Schreiner, B., Pinho, C. M., Filadi, R., Wiehager, B., Karlström, H., Pizzo, P., & Ankarcrona, M. (2016) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12863 · Cited by 170 · see citing works

Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

Stepanyants, N., Macdonald, P. J., Francy, C. A., Mears, J. A., Qi, X., & Ramachandran, R. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-06-0330 · Cited by 168 · see citing works

A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver

Sood, A., Jeyaraju, D. V., Prudent, J., Caron, A., Lemieux, P., McBride, H. M., Laplante, M., Tóth, K., & Pellegrini, L. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408061111 · Cited by 168 · see citing works

Mitochondrial dynamics in pulmonary arterial hypertension

Ryan, J. J., Dasgupta, A., Huston, J., Chen, K., & Archer, S. L. (2015) · Journal of Molecular Medicine · doi:10.1007/s00109-015-1263-5 · Cited by 163 · see citing works

A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro

Brandt, T., Cavellini, L., Kühlbrandt, W., & Cohen, M. M. (2016) · eLife · doi:10.7554/elife.14618 · Cited by 127 · see citing works

Mitochondrial clustering induced by overexpression of the mitochondrial fusion protein Mfn2 causes mitochondrial dysfunction and cell death

Huang, P., Yu, T., & Yoon, Y. (2007) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2007.04.002 · Cited by 123 · see citing works

The Mechanoenzymatic Core of Dynamin-related Protein 1 Comprises the Minimal Machinery Required for Membrane Constriction

Francy, C. A., Alvarez, F. J. D., Zhou, L., Ramachandran, R., & Mears, J. A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.610881 · Cited by 116 · see citing works

Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules

Strack, S., Wilson, T. J., & Cribbs, J. T. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201210045 · Cited by 113 · see citing works

Distinct mechanisms controlling rough and smooth endoplasmic reticulum-mitochondria contacts

Wang, P. T. C., Garcin, P. O., Fu, M., Masoudi, M., St-Pierre, P., Panté, N., & Nabi, I. R. (2015) · Journal of Cell Science · doi:10.1242/jcs.171132 · Cited by 111 · see citing works

Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons

Uo, T., Dworzak, J., Kinoshita, C., Inman, D. M., Kinoshita, Y., Horner, P. J., & Morrison, R. S. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.05.010 · Cited by 106 · see citing works

OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals

Baricault, L., Ségui, B., Guégand, L., Olichon, A., Valette, A., Larminat, F., & Lenaers, G. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.08.008 · Cited by 103 · see citing works

Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor

Clinton, R. W., Francy, C. A., Ramachandran, R., Qi, X., & Mears, J. A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.680025 · Cited by 103 · see citing works

Impaired OMA1 dependent OPA1 cleavage and reduced DRP1 fission activity combine to prevent mitophagy in OXPHOS dependent cells

MacVicar, T., & Lane, J. D. (2014) · Journal of Cell Science · doi:10.1242/jcs.144337 · Cited by 102 · see citing works

Analysis of ER-mitochondria contacts by correlative fluorescence microscopy and soft X-ray tomography of mammalian cells

Elgass, K., Smith, E. A., LeGros, M., Larabell, C. A., & Ryan, M. T. (2015) · Journal of Cell Science · doi:10.1242/jcs.169136 · Cited by 100 · see citing works

Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity

Macdonald, P. J., Francy, C. A., Stepanyants, N., Lehman, L., Baglio, A. J., Mears, J. A., Qi, X., & Ramachandran, R. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.680181 · Cited by 96 · see citing works

Mitochondrial outer and inner membrane fusion requires a modified carrier protein

Hoppins, S. C., Horner, J. S., Song, C., McCaffery, J. M., & Nunnari, J. M. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200809099 · Cited by 93 · see citing works

Mitochondrial dynamics: orchestrating the journey to advanced age

Biala, A. K., Dhingra, R., & Kirshenbaum, L. A. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.04.015 · Cited by 82 · see citing works

Phospholipid Association Is Essential for Dynamin-related Protein Mgm1 to Function in Mitochondrial Membrane Fusion

Rujiviphat, J., Meglei, G., Rubinstein, J. L., & McQuibban, G. A. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.044933 · Cited by 75 · see citing works

Morphological control of mitochondrial bioenergetics

Yoon, Y. (2015) · Frontiers in bioscience · doi:10.2741/4306 · Cited by 39 · see citing works

Mitochondrial Genome Maintenance 1 (Mgm1) Protein Alters Membrane Topology and Promotes Local Membrane Bending

Rujiviphat, J., Wong, M. K. Y., Won, A. M., Shih, Y., Yip, C. M., & McQuibban, G. A. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.03.006 · Cited by 32 · see citing works

Energy Metabolism of the Osteoblast: Implications for Osteoporosis

Lee, W.-C., Guntur, A. R., Long, F., & Rosen, C. J. (2017) · Endocrine Reviews · doi:10.1210/er.2017-00064 · Cited by 443 · see citing works

Defective mitophagy in Alzheimer’s disease

Pradeepkiran, J. A., & Reddy, P. H. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101191 · Cited by 367 · see citing works

Mitofusin 2: from functions to disease

Filadi, R., Pendin, D., & Pizzo, P. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0023-6 · Cited by 359 · see citing works

The Peroxisome-Mitochondria Connection: How and Why?

Fransen, M., Lismont, C., & Walton, P. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061126 · Cited by 351 · see citing works

New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury

Wang, J., Toan, S., & Zhou, H. (2020) · Angiogenesis · doi:10.1007/s10456-020-09720-2 · Cited by 311 · see citing works

Acute Pancreatitis: A Multifaceted Set of Organelle and Cellular Interactions

Habtezion, A., Gukovskaya, A. S., & Pandol, S. J. (2019) · Gastroenterology · doi:10.1053/j.gastro.2018.11.082 · Cited by 308 · see citing works

Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy

Hu, L., Ding, M., Tang, D., Gao, E., Li, C., Wang, K., Qi, B., Qiu, J., Zhao, H., Chang, P., et al. (2019) · Theranostics · doi:10.7150/thno.33684 · Cited by 256 · see citing works

Mitochondria in cancer

Grasso, D., Zampieri, L. X., Capelôa, T., de Velde, J. A. V., & Sonveaux, P. (2020) · Cell Stress · doi:10.15698/cst2020.06.221 · Cited by 231 · see citing works

Resveratrol and Brain Mitochondria: a Review

Jardim, F. R., de Rossi, F. T., Nascimento, M. X., Barros, R. G. D. S., Borges, P. A., Prescilio, I. C., & de Oliveira, M. R. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0448-z · Cited by 223 · see citing works

The mitochondria‐targeted anti‐oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance

Kang, L., Liu, S., Li, J., Tian, Y., Xue, Y., & Liu, X. (2020) · Cell Proliferation · doi:10.1111/cpr.12779 · Cited by 212 · see citing works

Challenges of fluoride pollution in environment: Mechanisms and pathological significance of toxicity – A review

Wu, S., Wang, Y., Iqbal, M., Mehmood, K., Li, Y., Tang, Z., & Zhang, H. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.119241 · Cited by 190 · see citing works

The role of mitochondria in axon development and regeneration

Smith, G. M., & Gallo, G. (2017) · Developmental Neurobiology · doi:10.1002/dneu.22546 · Cited by 170 · see citing works

Potential role of mitochondria-associated endoplasmic reticulum membrane proteins in diseases

Mao, H. Z., Chen, W., Chen, L., & Li, L. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115011 · Cited by 157 · see citing works

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy

Li, E., Li, X., Huang, J., Xu, C., Liang, Q., Ren, K., Bai, A., Lü, C., Qian, R., & Sun, N. (2020) · Protein & Cell · doi:10.1007/s13238-020-00713-x · Cited by 142 · see citing works

Mitochondrial quality surveillance as a therapeutic target in myocardial infarction

Zhu, H., Toan, S., Mui, D., & Zhou, H. (2020) · Acta Physiologica · doi:10.1111/apha.13590 · Cited by 142 · see citing works

Mitochondrial quality control in acute ischemic stroke

An, H., Zhou, B., & Ji, X. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211046992 · Cited by 136 · see citing works

Mitochondrial quality control in cartilage damage and osteoarthritis: new insights and potential therapeutic targets

Liu, D., Cai, Z., Yang, Y.-T., Lu, W.-H., Pan, L.-Y., Xiao, W.-F., & Li, Y. (2021) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2021.10.009 · Cited by 137 · see citing works

Mitochondrial Morphofunction in Mammalian Cells

Bulthuis, E. P., Adjobo-Hermans, M. J. W., Willems, P. H. G. M., & Koopman, W. J. H. (2018) · Antioxidants and Redox Signaling · doi:10.1089/ars.2018.7534 · Cited by 128 · see citing works

Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

Kubat, G. B., Bouhamida, E., Ülger, Ö., Türkel, İ., Pedriali, G., Ramaccini, D., Ekinci, Ö., Özerkliğ, B., Atalay, Ö., Patergnani, S., et al. (2023) · Mitochondrion · doi:10.1016/j.mito.2023.07.003 · Cited by 128 · see citing works

MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway

Zhao, S., Lu, C., Shi, Y., Li, J., Yun, Q., & Yang, H. (2021) · Cell Death and Disease · doi:10.1038/s41419-020-03336-6 · Cited by 120 · see citing works

Role of Mitochondria in Viral Infections

Elesela, S., & Lukacs, N. W. (2021) · Life · doi:10.3390/life11030232 · Cited by 113 · see citing works

Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion

Si, L., Fu, J., Liu, W., Hayashi, T., Nie, Y., Mizuno, K., Hattori, S., Fujisaki, H., Onodera, S., & Ikejima, T. (2019) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-019-03640-6 · Cited by 115 · see citing works

ROS as Regulators of Mitochondrial Dynamics in Neurons

Cid‐Castro, C., Hernández-Espinosa, D. R., & Morán, J. (2018) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-018-0584-7 · Cited by 111 · see citing works

Sphingolipids as a Culprit of Mitochondrial Dysfunction in Insulin Resistance and Type 2 Diabetes

Roszczyc-Owsiejczuk, K., & Zabielski, P. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.635175 · Cited by 112 · see citing works

Insights into Disease-Associated Tau Impact on Mitochondria

Szabo, L., Eckert, A., & Grimm, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176344 · Cited by 102 · see citing works

ß-tubulin contributes to Tongyang Huoxue decoction-induced protection against hypoxia/reoxygenation-induced injury of sinoatrial node cells through SIRT1-mediated regulation of mitochondrial quality surveillance

Chang, X., Li, Y., Liu, J., Wang, Y., Guan, X., Wu, Q., Zhou, Y., Zhang, X., chen, Y., Huang, Y., et al. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154502 · Cited by 103 · see citing works

Highlighting the endoplasmic reticulum-mitochondria connection: Focus on Mitofusin 2

Filadi, R., Greotti, E., & Pizzo, P. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.01.003 · Cited by 97 · see citing works

Multifunctional Mitochondrial AAA Proteases

Glynn, S. E. (2017) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2017.00034 · Cited by 81 · see citing works

Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes

Duan, X., Li, Y., Yi, K., Guo, F., Wang, H., Wu, P.-H., Yang, J., Mair, D. B., Morales, E. A., Kaláb, P., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-14068-3 · Cited by 79 · see citing works

Mitochondrial dynamics: The dynamin superfamily and execution by collusion

Ramachandran, R. (2017) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2017.07.039 · Cited by 77 · see citing works

Adenosine monophosphate activated protein kinase contributes to skeletal muscle health through the control of mitochondrial function

Yan, Y., Li, M., Lin, J., Ji, Y., Wang, K., Yan, D., Shen, Y., Wang, W., Huang, Z., Jiang, H., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.947387 · Cited by 81 · see citing works

Role of Oxidative Stress in Sensorineural Hearing Loss

Teraoka, M., Hato, N., Inufusa, H., & You, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084146 · Cited by 77 · see citing works

Mitochondrial Membrane Dynamics—Functional Positioning of OPA1

Lee, H., & Yoon, Y. (2018) · Antioxidants · doi:10.3390/antiox7120186 · Cited by 70 · see citing works

Polystyrene microplastics impair the functions of cultured mouse Leydig (TM3) and Sertoli (TM4) cells by inducing mitochondrial-endoplasmic reticulum damage

Grillo, G., Falvo, S., Latino, D., Baccari, G. C., Venditti, M., Fiore, M. M. D., Minucci, S., & Santillo, A. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116202 · Cited by 66 · see citing works

Dysfunctional mitochondria in age-related neurodegeneration: Utility of melatonin as an antioxidant treatment

Reiter, R. J., Sharma, R., Manucha, W. A., Rosales‐Corral, S., Chuffa, L. G. D. A., Loh, D., Luchetti, F., Balduini, W., & Govitrapong, P. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102480 · Cited by 66 · see citing works

Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition

Fan, R. Z., Guo, M. A., Luo, S., Cui, M., & Tieu, K. (2019) · Acta Neuropathologica Communications · doi:10.1186/s40478-019-0821-4 · Cited by 63 · see citing works

Mitochondria in Pathological Cardiac Hypertrophy Research and Therapy

Yang, D., Liu, H., Liu, F.-Y., Guo, Z., An, P., Wang, M., Yang, Z., Fan, D., & Tang, Q. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.822969 · Cited by 64 · see citing works

Recent Insights Into the Pathogenic Mechanism of Pancreatitis

Gukovskaya, A. S., Gorelick, F. S., Groblewski, G. E., Mareninova, O. A., Lugea, A., Antonucci, L., Waldron, R. T., Habtezion, A., Karin, M., Pandol, S. J., et al. (2019) · Pancreas · doi:10.1097/mpa.0000000000001298 · Cited by 64 · see citing works

Increased placental mitochondrial fusion in gestational diabetes mellitus: an adaptive mechanism to optimize feto-placental metabolic homeostasis?

Abbade, J. F., Klemetti, M. M., Farrell, A., Ermini, L., Gillmore, T., Sallais, J., Tagliaferro, A., Post, M., & Caniggia, I. (2020) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2019-000923 · Cited by 57 · see citing works

Parkin, an E3 Ubiquitin Ligase, Plays an Essential Role in Mitochondrial Quality Control in Parkinson’s Disease

Wang, X., Feng, S., Wang, Z., Yuan, Y., Chen, N., & Zhang, Y. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-00914-2 · Cited by 63 · see citing works

A-Kinase Anchoring Protein 1: Emerging Roles in Regulating Mitochondrial Form and Function in Health and Disease

Liu, Y., Merrill, R. A., & Strack, S. (2020) · Cells · doi:10.3390/cells9020298 · Cited by 55 · see citing works

ROCK1 activation-mediated mitochondrial translocation of Drp1 and cofilin are required for arnidiol-induced mitochondrial fission and apoptosis

Hu, J., Zhang, H., Li, J., Jiang, X., Zhang, Y., Wu, Q., Shen, L.-W., Shi, J., & Gao, N. (2020) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01545-7 · Cited by 56 · see citing works

Apigenin ameliorates hepatic lipid accumulation by activating the autophagy-mitochondria pathway

Hsu, M., Guo, B. C., Hu, P.-A., Chen, C. H., & Lee, T. (2021) · Journal of Food and Drug Analysis · doi:10.38212/2224-6614.3269 · Cited by 56 · see citing works

Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission

Zhang, X., Huang, W.-M., Tang, P.-C., Sun, Y. J., Zhang, X., Qiu, L., Yu, B.-C., Zhang, X.-Y., Hong, Y., He, Y., et al. (2021) · NeuroToxicology · doi:10.1016/j.neuro.2021.02.002 · Cited by 54 · see citing works

Mitochondrial impairment and repair in the pathogenesis of systemic lupus erythematosus

Zhao, L., Hu, X., Xiao, F., Zhang, X., Zhao, L., & Wang, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.929520 · Cited by 52 · see citing works

The multifaceted roles of mitochondria at the crossroads of cell life and death in cancer

Fontana, F., & Limonta, P. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.09.024 · Cited by 52 · see citing works

Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients

Mallard, J., Hucteau, E., Charles, A., Bender, L., Baeza, C., Pélissié, M., Trensz, P., Pflumio, C., Kalish‐Weindling, M., Gény, B., et al. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12991 · Cited by 50 · see citing works

The alterations of mitochondrial DNA in coronary heart disease

Hu, H., Lin, Y., Xu, X., Lin, S., Chen, X., & Wang, S. (2020) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2020.104412 · Cited by 51 · see citing works

Perspectives on mitochondrial relevance in cardiac ischemia/reperfusion injury

Pedriali, G., Ramaccini, D., Bouhamida, E., Wieckowski, M. R., Giorgi, C., Tremoli, E., & Pinton, P. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1082095 · Cited by 52 · see citing works

Mitochondrial disorder and treatment of ischemic cardiomyopathy: Potential and advantages of Chinese herbal medicine

Chang, X., Liu, J., Wang, Y., Guan, X., & Liu, R. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114171 · Cited by 50 · see citing works

p53/Drp1-dependent mitochondrial fission mediates aldosterone-induced podocyte injury and mitochondrial dysfunction

Yuan, Y., Zhang, A., Qi, J., Wang, H., Liu, X., Zhao, M., Duan, S., Huang, Z., Zhang, C., Wu, L., et al. (2017) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00055.2017 · Cited by 49 · see citing works

S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1

Chen, W., Xiang, H., Chen, R., Yang, J., Yang, X., Zhou, J., Liu, H., Zhao, S., Xiao, J., Pan, C., et al. (2019) · BMC Nephrology · doi:10.1186/s12882-019-1323-0 · Cited by 48 · see citing works

Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model

Valenti, D., Rossi, L., Marzulli, D., Bellomo, F., Rasmo, D. D., Signorile, A., & Vacca, R. A. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.09.014 · Cited by 46 · see citing works

Upregulation of mitochondrial dynamics is responsible for osteogenic differentiation of mesenchymal stem cells cultured on self-mineralized collagen membranes

Wan, M., Tang, X.-Y., Li, J., Gao, P., Wang, F., Shen, M., Gu, J., Tay, F. R., Chen, J., Niu, L., et al. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.09.039 · Cited by 45 · see citing works

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Meng, T., Guo, J., Liu, Z., Yin, Y., Wang, F., Han, Z., Lei, L., Ma, X., Xue, Y., Yue, W., et al. (2023) · Advanced Science · doi:10.1002/advs.202301940 · Cited by 44 · see citing works

MIEF2 over-expression promotes tumor growth and metastasis through reprogramming of glucose metabolism in ovarian cancer

Zhao, S., Zhang, X., Shi, Y., Lu, C., Song, T., Wu, B., Li, J., & Yang, H. (2020) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01802-9 · Cited by 44 · see citing works

The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury

Lee, H., Lee, T. J., Galloway, C. A., Zhi, W., Xiao, W. L., Bentley, K. L. D. M., Sharma, A. K., Teng, Y., Sesaki, H., & Yoon, Y. (2023) · Nature Communications · doi:10.1038/s41467-023-42564-0 · Cited by 42 · see citing works

Mitochondrial quality control dysfunction in osteoarthritis: Mechanisms, therapeutic strategies & future prospects

Cheung, C., Tu, S., Feng, Y., Wan, C., Ai, H., & Chen, Z. (2024) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2024.105522 · Cited by 43 · see citing works

Concurrent AFG3L2 and SPG7 mutations associated with syndromic parkinsonism and optic atrophy with aberrant OPA1 processing and mitochondrial network fragmentation

Magri, S., Fracasso, V., Plumari, M., Alfei, E., Ghezzi, D., Gellera, C., Rusmini, P., Poletti, A., Bella, D. D., Elia, A. E., et al. (2018) · Human Mutation · doi:10.1002/humu.23658 · Cited by 41 · see citing works

Spatial control of AMPK signaling at subcellular compartments

Chauhan, A. S., Li, Z., & Gan, B. (2020) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2020.1727840 · Cited by 40 · see citing works

Unraveling the Peculiar Features of Mitochondrial Metabolism and Dynamics in Prostate Cancer

Fontana, F., Anselmi, M., & Limonta, P. (2023) · Cancers · doi:10.3390/cancers15041192 · Cited by 39 · see citing works

Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission

Lu, B., Kennedy, B., Clinton, R. W., Wang, E. J., McHugh, D. R., Stepanyants, N., Macdonald, P. J., Mears, J. A., Qi, X., & Ramachandran, R. (2018) · Scientific Reports · doi:10.1038/s41598-018-29001-9 · Cited by 39 · see citing works

Selenium Alleviates Cadmium-Induced Mitophagy Through Fundc1-Mediated Mitochondrial Quality Control Pathway in the Lungs of Sheep

Lin, S., Yang, F., Hu, M., Chen, J., Chen, G., Hu, A., Li, X., Fu, D., Xing, C., Xiong, Z., et al. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.120954 · Cited by 38 · see citing works

The Loss of Mitochondrial Quality Control in Diabetic Kidney Disease

Dai, W., Lu, H., Chen, Y., Yang, D., Sun, L., & He, L. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.706832 · Cited by 38 · see citing works

Mitochondrial Fission Is Required for Blue Light-Induced Apoptosis and Mitophagy in Retinal Neuronal R28 Cells

Li, J., Zhang, K., Xu, D., Zhou, W.-T., Fang, W., Wan, Y., Yan, D., Guo, M., Tao, J., Zhou, W., et al. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00432 · Cited by 40 · see citing works

Unraveling the nexus of age, epilepsy, and mitochondria: exploring the dynamics of cellular energy and excitability

Xie, W., Koppula, S., Kale, M. B., Ali, L. S., Wankhede, N. L., Umare, M. D., Upaganlawar, A. B., Abdeen, A., Ebrahim, E., El‐Sherbiny, M., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1469053 · Cited by 36 · see citing works

Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission

Ganesan, V., Willis, S. D., Chang, K., Beluch, S., Cooper, K. F., & Strich, R. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-07-0463 · Cited by 35 · see citing works

circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury

Wang, Z., Zhao, Y., Sun, R., Sun, Y., Liu, D., Lin, M., Chen, Z., Zhou, J., Lv, L., Tian, X., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-03160-y · Cited by 35 · see citing works

Drp1-dependent mitochondrial fission mediates corneal injury induced by alkali burn

Zhang, K., Guo, M., Li, Q., Wang, X., Wan, Y., Yang, Z., He, M., Yi, Y.-M., Jiang, L., Qu, X.-H., et al. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.09.019 · Cited by 34 · see citing works

Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice

Wang, H., Zhu, S.-Q., Liu, J., Miao, C.-Y., Zhang, Y., & Zhou, B.-H. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.124607 · Cited by 32 · see citing works

Protective Effects of Inhibition of Mitochondrial Fission on Organ Function After Sepsis

Zhu, Y., Kuang, L., Wu, Y., Deng, H., She, H., Zhou, Y., Zhang, J., Liu, L., & Li, T. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.712489 · Cited by 33 · see citing works

Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion

Yu, H., Hong, X., Liu, L., Wu, Y., Xie, X., Fang, G., & Zhi, S. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.754005 · Cited by 33 · see citing works

Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1α/Mff regulation in head and neck squamous cell carcinoma

Wu, K., Mao, Y., Chen, Q., Zhang, B., Zhang, S., Wu, H., & Li, Y. (2021) · Cellular Oncology · doi:10.1007/s13402-021-00629-6 · Cited by 32 · see citing works

Empagliflozin ameliorates cardiac dysfunction in heart failure mice via regulating mitochondrial dynamics

Lyu, Y.-T., Huo, J., Jiang, W., Yang, W., Yang, W., Wang, S., Cheng, Y., Jiang, Z., & Shan, Q. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175531 · Cited by 32 · see citing works

Compartmentalized Signaling in Aging and Neurodegeneration

Benedetto, G. D., Iannucci, L. F., Surdo, N. C., Zanin, S., Conca, F., Grisan, F., Gerbino, A., & Lefkimmiatis, K. (2021) · Cells · doi:10.3390/cells10020464 · Cited by 29 · see citing works

Contribution of Massive Mitochondrial Fusion and Subsequent Fission in the Plant Life Cycle to the Integrity of the Mitochondrion and Its Genome

Rose, R. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115429 · Cited by 31 · see citing works

Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis

Dharaskar, S. P., Paithankar, K., Kanugovi, A., Kara, H. S., & Subbarao, S. A. (2020) · Mitochondrion · doi:10.1016/j.mito.2020.08.001 · Cited by 30 · see citing works

Mitochondrial dynamics and mitophagy involved in MPA-capped CdTe quantum dots-induced toxicity in the human liver carcinoma (HepG2) cell line

Wu, D., Lu, J., Ma, Y., Cao, Y., & Zhang, T. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.115681 · Cited by 30 · see citing works

Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells

Mollo, N., Nitti, M. P., Zerillo, L., Faicchia, D., Micillo, T., Accarino, R., Secondo, A., Petrozziello, T., Calı̀, G., Cicatiello, R., et al. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00606 · Cited by 29 · see citing works

Increased mitochondrial fission induces NLRP3/cGAS-STING mediated pro-inflammatory pathways and apoptosis in UVB-irradiated immortalized human keratinocyte HaCaT cells

Li, C., Zhu, Y., Liu, W., Hayashi, T., Xiang, W., He, S., Mizuno, K., Hattori, S., Fujisaki, H., & Ikejima, T. (2023) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2023.109558 · Cited by 28 · see citing works

Megamitochondria plasticity: Function transition from adaption to disease

Shang, Y., Li, Z., Cai, P., Li, W., Xu, Y., Zhao, Y., Xia, S., Shao, Q., & Wang, H. (2023) · Mitochondrion · doi:10.1016/j.mito.2023.06.001 · Cited by 28 · see citing works

Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy

Kim, D., & Roy, S. (2020) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.61.10.10 · Cited by 29 · see citing works

T-Cell Intracellular Antigens and Hu Antigen R Antagonistically Modulate Mitochondrial Activity and Dynamics by Regulating Optic Atrophy 1 Gene Expression

Carrascoso, I., Alcalde, J., Sánchez-Jiménez, C., González‐Sánchez, P., & Izquierdo, J. M. (2017) · Molecular and Cellular Biology · doi:10.1128/mcb.00174-17 · Cited by 28 · see citing works

Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer’s Disease Patients

Pakpian, N., Phopin, K., Kitidee, K., Govitrapong, P., & Wongchitrat, P. (2020) · Current Alzheimer Research · doi:10.2174/1567205017666201006162538 · Cited by 27 · see citing works

Acetylation in Mitochondria Dynamics and Neurodegeneration

Waddell, J., Banerjee, A., & Kristián, T. (2021) · Cells · doi:10.3390/cells10113031 · Cited by 27 · see citing works

Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy

Wang, N., Huang, R., Yang, K., He, Y., Gao, Y., & Dong, D. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17147 · Cited by 27 · see citing works

The role of mitochondrial oxidative stress in hearing loss

González-González, S. (2017) · Neurological Disorders and Therapeutics · doi:10.15761/ndt.1000117 · Cited by 27 · see citing works

A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury

Soundararajan, R., Hernández‐Cuervo, H., Stearns, T. M., Griswold, A. J., Patil, S. S., Fukumoto, J., Narala, V. R., Galam, L., Lockey, R. F., & Kolliputi, N. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.980723 · Cited by 26 · see citing works

Age-Related Decline in Nrf2/ARE Signaling Is Associated with the Mitochondrial DNA Damage and Cognitive Impairments

Gureev, A. P., Khorolskaya, V. G., Sadovnikova, I. S., Shaforostova, E. A., Cherednichenko, V. R., Burakova, I. Y., Plotnikov, E. Y., & Popov, V. N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315197 · Cited by 26 · see citing works

Interplay between NAD+ and acetyl‑CoA metabolism in ischemia-induced mitochondrial pathophysiology

Klimova, N., Long, A., Scafidi, S., & Kristián, T. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.09.025 · Cited by 26 · see citing works

A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity

Zou, Y.-Y., Chen, Z.-L., Sun, C.-C., Yang, D., Zhou, Z.-Q., Xiao, Q., Peng, X.-Y., & Tang, C.-F. (2022) · Nutrients · doi:10.3390/nu14091975 · Cited by 24 · see citing works

Cold stress causes liver damage by inducing ferroptosis through the p38 MAPK/Drp1 pathway

Huang, Y., Xiong, K., Wang, A., Wang, Z., Cui, Q., Xie, H., Yang, T., Xu, F., Jiang, W., Tan, X., et al. (2023) · Cryobiology · doi:10.1016/j.cryobiol.2023.104563 · Cited by 24 · see citing works

DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen

Bruno, S. R., Kumar, A., Mark, Z. F., Chandrasekaran, R., Nakada, E. M., Chamberlain, N., Korwin-Mihavics, B. R., Walzer, J., Cahoon, J. M., Dixon, A. E., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222011125 · Cited by 24 · see citing works

Deciphering psoriasis. A bioinformatic approach

Melero, J. L., Andrades, S., Arola, L., & Romeu, A. (2017) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2017.11.010 · Cited by 25 · see citing works

Alpha Lipoamide Ameliorates Motor Deficits and Mitochondrial Dynamics in the Parkinson’s Disease Model Induced by 6-Hydroxydopamine

Zhou, B. O., Wen, M., Lin, X., Chen, Y., Gou, Y., Li, Y., Zhang, Y., Li, H.-W., & Tang, L. (2017) · Neurotoxicity Research · doi:10.1007/s12640-017-9819-5 · Cited by 23 · see citing works

Impairment of mitochondrial dynamics involved in iron oxide nanoparticle‐induced dysfunction of dendritic cells was alleviated by autophagy inhibitor 3‐methyladenine

Zhang, T.-G., Zhang, Y., Zhou, Q., Wang, X., & Zhan, L. (2020) · Journal of Applied Toxicology · doi:10.1002/jat.3933 · Cited by 23 · see citing works

Long-term oral administration of naringenin counteracts aging-related retinal degeneration via regulation of mitochondrial dynamics and autophagy

Chen, G., Zeng, L., Yan, F., Liu, J., Qin, M., Wang, F., & Zhang, X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.919905 · Cited by 23 · see citing works

Fetal Cerebral Artery Mitochondrion as Target of Prenatal Alcohol Exposure

Bukiya, A. N. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16091586 · Cited by 23 · see citing works

Electroacupuncture preconditioning protects against focal cerebral ischemia/reperfusion injury via suppression of dynamin-related protein 1

Wang, M., Zhang, G., Yang, P., Yin, Z., Chen, H., Ma, F., Wang, B., Sun, L., Bi, Y., & Shi, F. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.224373 · Cited by 22 · see citing works

Altered Mitochondrial Dynamics, Biogenesis, and Functions in the Paclitaxel-Resistant Lung Adenocarcinoma Cell Line A549/Taxol

Zhou, X., Li, R., Chen, R., & Liu, J. (2020) · Medical Science Monitor · doi:10.12659/msm.918216 · Cited by 22 · see citing works

Mechanisms of Mitochondrial Fission and FusionPreprint

van der Bliek, A. M., Shen, Q., & Kawajiri, S. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a011072 · Cited by 861 · see citing works

Mitochondrial Dynamics: Mechanisms and Pathologies

Lee, H., & Yoon, Y. (2012) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0021867 · Cited by 3 · see citing works

Molecular mechanisms of mitochondrial dynamics

Tábara, L. C., Segawa, M., & Prudent, J. (2024) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-024-00785-1 · Cited by 431 · see citing works

Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders

Ojaimi, M. A., Salah, A., & El‐Hattab, A. W. (2022) · Membranes · doi:10.3390/membranes12090893 · Cited by 130 · see citing works

Mitochondrial dynamics: overview of molecular mechanisms

Tilokani, L., Nagashima, S., Paupe, V., & Prudent, J. (2018) · Essays in Biochemistry · doi:10.1042/ebc20170104 · Cited by 1,397 · see citing works