Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 108

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Significant genetic differentiation between Poland and Germany follows present-day political borders, as revealed by Y-chromosome analysis

Kayser, Manfred, Lao, Oscar, Anslinger, Katja, Augustin, Christa, Bargel, Grazyna, Edelmann, Jeanett, Elias, Sahar, Heinrich, Marielle, Henke, Jürgen, Henke, Lotte, Hohoff, Carsten, Illing, Anett, Jonkisz, Anna, Kuzniar, Piotr, Lebioda, Arleta, Lessig, Rüdiger, Lewicki, Slawomir, Maciejewska, Agnieszka, Monies, Dorota Marta, Pawłowski, Ryszard, Poetsch, Micaela, Schmid, Dagmar, Schmidt, Ulrike, Schneider, Peter M., Stradmann-Bellinghausen, Beate, Szibor, Reinhard, Wegener, Rudolf, Wozniak, Marcin, Zoledziewska, Magdalena, Roewer, Lutz, Dobosz, Tadeusz, Ploski, Rafal·2005·Human Genetics
DOI 10.1007/s00439-005-1333-9
Open this paper in CoChat — free account

Abstract

To test for human population substructure and to investigate human population history we have analysed Y-chromosome diversity using seven microsatellites (Y-STRs) and ten binary markers (Y-SNPs) in samples from eight regionally distributed populations from Poland (n = 913) and 11 from Germany (n = 1,215). Based on data from both Y-chromosome marker systems, which we found to be highly correlated (r = 0.96), and using spatial analysis of the molecular variance (SAMOVA), we revealed statistically significant support for two groups of populations: (1) all Polish populations and (2) all German populations. By means of analysis of the molecular variance (AMOVA) we observed a large and statistically significant proportion of 14% (for Y-SNPs) and 15% (for Y-STRs) of the respective total genetic variation being explained between both countries. The same population differentiation was detected using Monmonier's algorithm, with a resulting genetic border between Poland and Germany that closely resembles the course of the political border between both countries. The observed genetic differentiation was mainly, but not exclusively, due to the frequency distribution of two Y-SNP haplogroups and their associated Y-STR haplotypes: R1a1*, most frequent in Poland, and R1*(xR1a1), most frequent in Germany. We suggest here that the pronounced population differentiation between the two geographically neighbouring countries, Poland and Germany, is the consequence of very recent events in human po…

Overview

Integrity signals

Registry

Crossref · 10.1007/s00439-005-1333-9

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 47

  1. Barbujani GV (2000) Geographic patterns: how to identify them and why. Hum Biol 72:133–153
  2. Barbujani G, Goldstein DB (2004) Africans and Asians abroad: genetic diversity in Europe. Annu Rev Genomics Hum Genet 5:119–150 · DOI
  3. Bender K, Stradmann-Bellinghausen B, Rittner C, Schneider PM (2003) Comparative analysis of STRs and SNPs on the Y-chromosome in Germans, Chinese and Thais. Legal Med 5:164–168 · DOI
  4. Bosch E, Calafell F, Rosser ZH, Nørby S, Lynnerup N, Hurles ME, Jobling MA (2003) High level of male-biased Scandinavian admixture in Greenlandic Inuit shown by Y-chromosomal analysis. Hum Genet 112:353–363 · DOI
  5. Bowcock AM, Ruiz-Linares A, Tomfohrde J, Minch E, Kidd JR, Cavalli-Sforza LL (1994) High resolution of human evolutionary trees with polymorphic microsatellites. Nature 368:455–457 · DOI
  6. Capelli C, Redhead N, Abernethy JK, Gratrix F, Wilson JF, Moen T, Hervig T, Richards M, Stumpf MPH, Underhill PA, Bradshaw P, Shaha A, Thomas MG, Bradman N, Goldstein DB (2003) A Y chromosome census of the British Isles. Curr Biol 13:979–984 · DOI
  7. Cordaux R, Aunger R, Bentley G, Nasidze I, Sirajuddin SM, Stoneking M (2004) Independent origins of Indian caste and tribal paternal lineages. Curr Biol 14:231–235 · DOI
  8. de Knijff P (2000) Messages through bottlenecks: on the combined use of slow and fast evolving polymorphic markers on the human Y chromosome. Am J Hum Genet 67:1055–1061 · DOI
  9. Dupanloup I, Schneider S, Excoffier L (2002) A simulated annealing approach to define the genetic structure of populations. Mol Ecol 11:2571–2571 · DOI
  10. Hammer MF (1994) A recent insertion of an Alu element on the Y chromosome is a useful marker for human population studies. Mol Biol Evol 11:749–761
  11. Hammer MF, Horai S (1995) Y chromosomal DNA variation and the peopling of Japan. Am J Hum Genet 56:951–962
  12. Hurles ME, Maund E, Nicholson J, Bosch E, Renfrew C, Sykes BC, Jobling MA (2003) Native American Y chromosomes in Polynesia: the genetic impact of the Polynesian slave trade. Am J Hum Genet 72:1282–1287 · DOI · Paper page
  13. Jin L, Su B (2000) Natives or immigrants: modern human origin in East Asia. Nat Rev Genet 1:126–133 · DOI
  14. Jobling M, Tyler-Smith C (2003) The human Y chromosome: an evolutionary marker comes of age. Nat Rev Genet 4:598–612 · DOI
  15. Kayser M (2003) The human Y chromosome—introduction into genetics and applications. Forensic Sci Rev 15:77–89
  16. Kayser M, Brauer S, Weiss G, Underhill P, Roewer L, Schiefenhövel W, Stoneking M (2000a) Melanesian origin of polynesian Y chromosomes. Curr Biol 10:1237–1246 · DOI · Paper page
  17. Kayser M, Roewer L, Hedman M, Henke L, Henke J, Brauer S, Krüger C, Krawczak M, Nagy M, Dobosz T, Szibor R, de Knijff P, Stoneking M, Sajantila A (2000b) Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs. Am J Hum Genet 66:1580–1588 · DOI
  18. Kayser M, Brauer S, Weiss G, Schiefenhövel W, Underhill P, Stoneking M (2001) Independent histories of Y chromosomes from Melanesia and Australia. Am J Hum Genet 68:173–190 · DOI
  19. Kayser M, Brauer S, Willuweit S, Schädlich H, Batzer MA, Zawacki J, Prinz M, Roewer L, Stoneking M (2002) Online Y-chromosomal short tandem repeat haplotype reference database (YHRD) for US populations. J Forensic Sci 47:513–519 · DOI
  20. Kayser M, Brauer S, Weiss G, Schiefenhövel W, Underhill P, Shen P, Oefner P, Tommaseo-Ponzetta M, Stoneking M (2003) Reduced Y-chromosome, but not mtDNA, diversity in human populations from West New Guinea. Am J Hum Genet 72:281–302 · DOI · Paper page
  21. Ke X, Collins A, Ye S (2001a) PIRA PCR designer for restriction analysis of single nucleotide polymorphisms. Bioinformatics 17:838–839 · DOI
  22. Ke Y, Su B, Song X, Lu D, Chen L, Li H, Qi C, Marzuki S, Deka R, Underhill P, Xiao C, Shriver M, Lell J, Wallace D, Wells RS, Seielstad M, Oefner P, Zhu D, Jin J, Huang W, Chakraborty R, Chen Z, Jin L (2001b) African origin of modern humans in east Asia: a tale of 12,000 Y chromosomes. Science 292:1151–1152 · DOI
  23. Lessig R, Willuweit S, Krawczak M, Wu F-C, Pu C-E, Kim W, Henke L, Henke J, Miranda J, Hidding M, Benecke M, Schmitt C, Magno M, Calacal G, Delfin FC, de Ungria MCA, Elias S, Augustin C, Tun Z, Honda K, Kayser M, Gusmao L, Amorim A, Alves C, Hou Y, Keyser C, Ludes B, Klintschar M, Immel UD, Reichenpfader B, Zaharova B, Roewer L (2003) Asian online Y-STR haplotype reference database. Legal Med 5:S160–S163 · DOI
  24. Lessig R, Zoledziewska M, Fahr K, Edelmann J, Kostrzewa M, Dobosz T, Kleemann W (2005) Y-SNP-genotyping—a new approach in forensic analysis. Forensic Sci Int (in press), available online from the Forensic Sci Int website doi:10.1016/j.forsciint.2004.09.129 · DOI
  25. Manni FC, Heyer GE (2004) Geographic patterns of (genetic, morphologic, linguistic) variation: how barriers can be detected by “Monmonier’s algorithm”. Hum Biol 76:173–190 · DOI
  26. Mantel N (1967) The detection of disease clustering and a generalized regression approach. Cancer Res 27:209–220
  27. Nasidze I, Ling ES, Quinque D, Dupanloup I, Cordaux R, Rychkov S, Naumova O, Zhukova O, Sarraf-Zadegan N, Naderi GA, Asgary S, Sardas S, Farhud DD, Sarkisian T, Asadov C, Kerimov A, Stoneking MM (2004) Mitochondrial DNA and Y-chromosome variation in the Caucasus. Ann Hum Genet 68:205–221 · DOI · Paper page
  28. Ploski R, Wozniak M, Pawlowski R, Monies DM, Branicki W, Kupiec T, Kloosterman A, Dobosz T, Bosch E, Nowak M, Lessig R, Jobling MA, Roewer L, Kayser M (2002) Homogeneity and distinctiveness of Polish paternal lineages revealed by Y chromosome microsatellite haplotype analysis. Hum Genet 110:592–600 · DOI
  29. Roewer L, Krawczak M, Willuweit S, Nagy M, Alves C, Amorim A, Anslinger K, Augustin C, Betz A, Bosch E, Caglia A, Carracedo A, Corach D, Dobosz T, Dupuy BM, Furedi S, Gehrig C, Gusmao L, Henke J, Henke L, Hidding M, Hohoff C, Hoste B, Jobling MA, Kargel HJ, de Knijff P, Lessig R, Liebherr E, Lorente M, Martinez-Jarreta B, Nievas P, Nowak M, Parson W, Pascali VL, Penacino G, Ploski R, Rolf B, Sala A, Schmidt U, Schmitt C, Schneider PM, Szibor R, Teifel-Greding J, Kayser M (2001) Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes. Forensic Sci Int 118:106–113 · DOI
  30. Roewer L, Croucher PJP, Willuweit S, Lu TT, Kayser M, Lessig R, de Knijff P, Jobling MA, Tyler-Smith C, Krawczak M (2005) Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Hum Genet 116:279–291
  31. Rootsi S, Magri C, Kivisild T, Benuzzi G, Help H, Bermisheva M, Kutuev I, Barac L, Pericic M, Balanovsky O, Pshenichnov A, Dion D, Grobei M, Zhivotovsky LA, Battaglia V, Achilli A, Al-Zahery N, Parik J, King R, Cinnioglu C, Khusnutdinova E, Rudan P, Balanovska E, Scheffrahn W, Simonescu M, Brehm A, Goncalves R, Rosa A, Moisan JP, Chaventre A, Ferak V, Furedi S, Oefner PJ, Shen P, Beckman L, Mikerezi I, Terzic R, Primorac D, Cambon-Thomsen A, Krumina A, Torroni A, Underhill PA, Santachiara-Benerecetti AS, Villems R, Semino O (2004) Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in Europe. Am J Hum Genet 75:128–137 · DOI
  32. Rosenberg M (2001) Pattern analysis, spatial statistics, and geographic exegesis. Version 1.1, 1.1 edn. Department of Biology, Arizona State University, Tempe
  33. Rosser ZH, Zerjal T, Hurles ME, Adojaan M, Alavantic D, Amorim A, Amos W, Armenteros M, Arroyo E, Barbujani G, Beckamnn L, Bertranpetit J, Bosch E, Bradley DG, Brede G, Cooper GC, Corte-Real HBSM, de Knijff P, Decorte R, Dubrova YE, Evgrafov O, Gilissen A, Glisic S, Gölge M, Hill EW, Jeziorowska A, Kalaydjieva L, Kayser M, Kravchenco SA, Lavinha J, Livshits LA, Maria S, McElreavy K, Meitinger TA, Melegh B, Mitchell RJ, Nicholson J, Norby S, Noveletto A, Pandya A, Parik J, Patsalis PC, Pereira L, Peterlin B, Pielberg G, Prata MJ, Previdere C, Rajczy K, Roewer L, Rootsi S, Rubinsztein DC, Saillard J, Santos FR, Shlumukova M, Stefanescu G, Sykes BC, Tolun A, Villems R, Tyler-Smith C, Jobling MA (2000) Y-chromosomal diversity within Europe is clinal and influenced primarily by geography, rather than by language. Am J Hum Genet 67:1526–1543 · DOI · Paper page
  34. Schneider S, Roessli D, Excoffier L (2000) Arlequin Version 2.000: a software for population genetics data analysis. Genetics and Biometry Laboratory, University of Geneva, Geneva
  35. Schurr TG (2004) The peopling of the New World: perspectives from molecular Anthropology. Annu Rev Anthropol 33:551–583 · DOI
  36. Semino O, Passarino G, Oefner PJ, Lin AA, Arbuzova S, Beckman LE, De Benedictis G, Francalacci P, Kouvatsi A, Limborska S, Marcikiae M, Maik A, Mika B, Primorac D, Santachiara-Benerecetti AS, Cavalli-Sforza LL, Underhill PA (2000) The genetic legacy of palaeolithic Homo sapiens sapiens in extant Europeans: a Y chromosome perspective. Science 290:1155–1159 · DOI
  37. Semino O, Santachiara-Benerecetti AS, Falaschi F, Cavalli-Sforza LL, Underhill PA (2002) Ethiopians and Khoisan share the deepest clades of the human Y-chromosome phylogeny. Am J Hum Genet 70:265–268 · DOI
  38. Sokal RR, Oden NL (1978) Spatial autocorrelation in biology. 1. Methodology. Biol J Linnean Soc 10:199–228 · DOI
  39. Soodyall H, Nebel A, Morar B, Jenkins T (2003) Genealogy and genes: tracing the founding fathers of Tristan da Cunha. Eur J Hum Genet 11:705–709 · DOI
  40. Stoneking M, Soodyall H (1996) Human evolution and the mitochondrial genome. Curr Opin Genet Dev 6:731–736 · DOI
  41. Thomson R, Pritchard JK, Shen P, Oefner PJ, Feldman MW (2000) Recent common ancestry of human Y chromosomes: evidence from DNA sequence data. Proc Natl Acad Sci USA 97:7360–7365 · DOI
  42. Underhill PA, Shen P, Lin AA, Jin L, Passarino G, Yang WH, Kauffman E, Bonne-Tamir B, Bertranpetit J, Francalacci P, Ibrahim M, Jenkins T, Kidd JR, Mehdi SQ, Seielstad MT, Wells RS, Piazza A, Davis RW, Feldman MW, Cavalli-Sforza LL, Oefner PJ (2000) Y-chromosome sequence variation and the history of human populations. Nat Genet 26:358–361 · DOI · Paper page
  43. Weale ME, Weiss DA, Jager RF, Bradman N, Thomas M (2002) Y chromosome evidence for Anglo-Saxon mass migration. Mol Bio Evol 19:1008–1021 · DOI
  44. Wells RS, Yuldasheva N, Ruzibakiev R, Underhill PA, Evseeva I, Blue-Smith J, Jin L, Su B, Pitchappan R, Shanmugalakshmi S, Balakrishnan K, Read M, Pearson NM, Zerjal T, Webster MT, Zholoshvili I, Jamarjashvili E, Gambarov S, Nikbin B, Dostiev A, Aknazarov O, Zalloua P, Tsoy I, Kitaev M, Mirrakhimov M, Chariev A, Bodmer WF (2001) The Eurasian heartland: a continental perspective on Y-chromosome diversity. Proc Natl Acad Sci USA 98:10244–10249 · DOI · Paper page
  45. Wilson JF, Weiss DA, Richards M, Thomas MG, Bradman N, Goldstein DB (2001) Genetic evidence for different male and female roles during cultural transitions in the British Isles. Proc Natl Acad Sci USA 98:5078–5083 · DOI
  46. Zegura SL, Karafet TM, Zhivotovsky LA, Hammer MF (2004) High-resolution SNPs and microsatellite haplotypes point to a single, recent entry of Native American Y chromosomes into the Americas. Mol Biol Evol 21:164–175 · DOI
  47. Zerjal T, Dashnyam B, Pandya A, Kayser M, Roewer L, Santos F, Schiefenhövel W, Fretwell N, Jobling MA, Harihara S, Shimizu K, Semjidmaa D, Sajantila A, Salo P, Crawford MH, Evgrafov O, Tyler-Smith C (1997) Genetic relationships of Asians and northern Europeans revealed by Y-chromosomal DNA analysis. Am J Hum Genet 60:1174–1183

Cited by

See all 108

Metadata

Authors
Kayser, M., Lao, O., Anslinger, K., Augustin, C., Bargel, G., Edelmann, J., Elias, S., Heinrich, M., Henke, J., Henke, L., Hohoff, C., Illing, A., Jonkisz, A., Kuzniar, P., Lebioda, A., Lessig, R., Lewicki, S., Maciejewska, A., Monies, D. M., Pawłowski, R., Poetsch, M., Schmid, D., Schmidt, U., Schneider, P. M., Stradmann-Bellinghausen, B., Szibor, R., Wegener, R., Wozniak, M., Zoledziewska, M., Roewer, L., Dobosz, T., & Ploski, R.
Venue
Human Genetics
Publisher
Springer Science and Business Media LLC
Published
2005-06-16
Volume
117
Issue
5
Pages
428-443
ISSN
  • 0340-6717
  • 1432-1203
DOI
10.1007/s00439-005-1333-9
Cited by
108
References
1
Language
en
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review