Resistance exercise and secondary lymphedema in breast cancer survivors—a systematic review
Abstract
Purpose The aim of the present review was to determine effects of strength exercise on secondary lymphedema in breast cancer patients.Methods Research was conducted by using the databases PubMed/Medline and Embase. Randomized controlled trials published from January 1966 to May 2015 investigating the effects of resistance exercise on breast cancer patients with or at risk of secondary lymphedema in accordance with the American College of Sports Medicine exercise guidelines for cancer survivors were included in the present study.Results Nine original articles with a total of 957 patients met the inclusion criteria. None of the included articles showed adverse effects of a resistance exercise intervention on lymphedema status. In all included studies, resistance exercise intensity was described as moderate to high.Conclusions Strength exercise seems not to have negative effects on lymphedema status or might not increase risk of development of lymphedema in breast cancer patients. Further research is needed in order to investigate the effects of resistance exercise for patients suffering from lymphedema.
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There is a history of clinical recommendations to refrain from aerobic or resistance training to avoid onset or exacerbation of lymphedema.
“There is a history of clinical recommendations to refrain from aerobic or resistance training in order to avoid onset or exacerbation of lymphedema(33, 34).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [34]
Cites
Downs, S. H., & Black, N. (1998) · Journal of Epidemiology and Community Health · doi:10.1136/jech.52.6.377 · Cited by 8,252 · see citing works
American College of Sports Medicine Roundtable on Exercise Guidelines for Cancer Survivors
Schmitz, K. H., Courneya, K. S., Matthews, C., Demark-Wahnefried, W., GALVÃO, D. A., Pinto, B. M., IRWIN, M. L., WOLIN, K. Y., SEGAL, R. J., LUCIA, A., et al. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181e0c112 · Cited by 2,781 · see citing works
Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis
DiSipio, T., Rye, S., Newman, B. M., & Hayes, S. C. (2013) · The Lancet Oncology · doi:10.1016/s1470-2045(13)70076-7 · Cited by 1,896 · see citing works
Courneya, K. S., SEGAL, R. J., Mackey, J. R., Gelmon, K. A., Reid, R. D., Friedenreich, C. M., Ladha, A. B., Proulx, C., Vallance, J. K., Lane, K. N., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.08.2024 · Cited by 1,182 · see citing works
Youlden, D. R., Cramb, S. M., Dunn, N., Muller, J., Pyke, C., & Baade, P. D. (2012) · Cancer Epidemiology · doi:10.1016/j.canep.2012.02.007 · Cited by 709 · see citing works
Meta-Analysis: Exercise Therapy for Nonspecific Low Back Pain
Hayden, J. A., van Tulder, M. W., Malmivaara, A. V., & Koes, B. W. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-9-200505030-00013 · Cited by 611 · see citing works
Weight lifting in women with breast-cancer-related lymphedema
Schmitz, K. H., Ahmed, R. L., Troxel, A., Cheville, A., Smith, R., Lewis-Grant, L., Bryan, C. J., Williams-Smith, C. T., & Greene, Q. P. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810118 · Cited by 578 · see citing works
Lymphedema beyond breast cancer
Cormier, J. N., Askew, R. L., Mungovan, K. S., Xing, Y., Ross, M. I., & Armer, J. M. (2010) · Cancer · doi:10.1002/cncr.25458 · Cited by 512 · see citing works
Shih, Y. T., Xu, Y., Cormier, J. N., Giordano, S. H., Ridner, S. H., Buchholz, T. A., Perkins, G. H., & Elting, L. S. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.18.3517 · Cited by 492 · see citing works
Bonner Venenstudie der Deutschen Gesellschaft für Phlebologie
Pannier-Fischer, F., Bromen, K., Schuldt, K., et al. (2003) · Phlebologie · doi:10.1055/s-0037-1617353 · Cited by 472 · see citing works
Weight Lifting for Women at Risk for Breast Cancer–Related Lymphedema: A Randomized Trial
Schmitz, K. H., Ahmed, R. L., Troxel, A. B., Cheville, A., Lewis-Grant, L., Smith, R., Bryan, C. J., Williams-Smith, C. T., & Chittams, J. (2010) · JAMA · doi:10.1001/jama.2010.1837 · Cited by 410 · see citing works
Weight Lifting in Women with Breast-Cancer–Related Lymphedema
Rourke, L. R., Askew, R. L., & Cormier, J. N. (2010) · Breast Diseases A Year Book Quarterly · doi:10.1016/s1043-321x(10)79464-9 · Cited by 410 · see citing works
Lymphedema and Quality of Life in Breast Cancer Survivors: The Iowa Women's Health Study
Ahmed, R. L., Prizment, A. E., Lazovich, D., Schmitz, K. H., & Folsom, A. R. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2008.16.4731 · Cited by 397 · see citing works
Padberg, F. T., Johnston, M. V., & Sisto, S. A. (2003) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2003.09.036 · Cited by 343 · see citing works
Reliability and Validity of Arm Volume Measurements for Assessment of Lymphedema
Taylor, R. J., Jayasinghe, U. W., Koelmeyer, L. A., Ung, O., & Boyages, J. (2006) · Physical Therapy · doi:10.1093/ptj/86.2.205 · Cited by 332 · see citing works
Randomized Controlled Trial of Weight Training and Lymphedema in Breast Cancer Survivors
Ahmed, R. L., Thomas, W., Yee, D., & Schmitz, K. H. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.03.6749 · Cited by 327 · see citing works
Sander, A. P., Hajer, N. M., Hemenway, K., & Miller, A. C. (2002) · Physical Therapy · doi:10.1093/ptj/82.12.1201 · Cited by 314 · see citing works
Impact of Resistance Training in Cancer Survivors
Strasser, B., Steindorf, K., Wiskemann, J., & Ulrich, C. M. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31829a3b63 · Cited by 291 · see citing works
A Brief Review of Critical Processes in Exercise-Induced Muscular Hypertrophy
Phillips, S. M. (2014) · Sports Medicine · doi:10.1007/s40279-014-0152-3 · Cited by 281 · see citing works
Cancer-Related Lymphedema Risk Factors, Diagnosis, Treatment, and Impact: A Review
Paskett, E. D., Dean, J. A., Oliveri, J. M., & Harrop, J. P. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2012.41.8574 · Cited by 251 · see citing works
Gardner, J. R., Livingston, P. M., & Fraser, S. F. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2013.49.5523 · Cited by 243 · see citing works
Sukul, D. M. K. S. K., den Hoed, P. T., Johannes, E. J., van Dolder, R., & Benda, E. (1993) · Journal of Biomedical Engineering · doi:10.1016/0141-5425(93)90062-4 · Cited by 211 · see citing works
Battaglini, C. L. (2014) · World Journal of Clinical Oncology · doi:10.5306/wjco.v5.i2.177 · Cited by 188 · see citing works
The grading of lymphedema in oncology clinical trials
Cheville, A. L., McGarvey, C. L., Petrek, J. A., et al. (2003) · Seminars in Radiation Oncology · doi:10.1016/s1053-4296(03)00038-9 · Cited by 171 · see citing works
Cormie, P., Pumpa, K. L., Galvao, D. A., Turner, E., Spry, N. A., Saunders, C. M., Zissiadis, Y., & Newton, R. U. (2013) · Journal of Cancer Survivorship · doi:10.1007/s11764-013-0284-8 · Cited by 170 · see citing works
Exercise in patients with lymphedema: a systematic review of the contemporary literature
Kwan, M. L., Cohn, J. C., Armer, J. M., Stewart, B. R., & Cormier, J. N. (2011) · Journal of Cancer Survivorship · doi:10.1007/s11764-011-0203-9 · Cited by 165 · see citing works
Kilbreath, S. L., Refshauge, K. M., Beith, J. M., Ward, L. C., Lee, M., Simpson, J. M., & Hansen, R. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-1964-1 · Cited by 142 · see citing works
Exercise and Secondary Lymphedema
Hayes, S. C., Reul-Hirche, H. M., & Turner, J. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31818b98fb · Cited by 131 · see citing works
Stuiver, M. M., ten Tusscher, M. R., Agasi-Idenburg, C. S., Lucas, C., Aaronson, N. K., & Bossuyt, P. M. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009765.pub2 · Cited by 111 · see citing works
Anderson, R. T., Kimmick, G. G., McCoy, T. P., Hopkins, J. O., Levine, E. A., Miller, G., Ribisl, P. M., & Mihalko, S. L. (2011) · Journal of Cancer Survivorship · doi:10.1007/s11764-011-0208-4 · Cited by 111 · see citing works
Minimal limb volume change has a significant impact on breast cancer survivors.
Cormier, J. N., Xing, Y., Zaniletti, I., Askew, R. L., Stewart, B. R., & Armer, J. M. (2009) · PubMed · Cited by 109 · see citing works
Schmitz, K. H. (2009) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e3181c5cd5a · Cited by 93 · see citing works
Cormie, P., Galvao, D. A., Spry, N. A., & Newton, R. U. (2013) · Integrative Cancer Therapies · doi:10.1177/1534735413477194 · Cited by 78 · see citing works
Hasenoehrl, T., Keilani, M. Y., Komanadj, T. S., Mickel, M., Margreiter, M., Marhold, M., & Crevenna, R. (2015) · Supportive Care in Cancer · doi:10.1007/s00520-015-2782-x · Cited by 66 · see citing works
Self-citationKampshoff, C. S., Buffart, L. M., Schep, G., van Mechelen, W., Brug, J., & Chinapaw, M. J. M. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-658 · Cited by 29 · see citing works
Prevalence of Stemmer's sign in the general population
Hoffmann, B. H., Stang, A., Jöckel, K., et al. (2007) · Phlebologie · doi:10.1055/s-0037-1622201 · Cited by 18 · see citing works
Vitucci, C., Tirelli, C., Graziano, F., & Santoro, E. (2000) · Journal of Surgical Oncology · doi:10.1002/1096-9098(200006)74:2 · Cited by 16 · see citing works
Aerobes Ausdauertraining fur Krebspatienten
Crevenna, R., Zielinski, C. C., Keilani, M. Y., Schmidinger, M., Bittner, C., Nuhr, M. J., Nur, H., Marosi, C., Fialka‐Moser, V., & Quittan, M. (2003) · Wiener Medizinische Wochenschrift · doi:10.1046/j.1563-258x.2003.02080.x · Cited by 15 · see citing works
Self-citationPrediction of cancer incidence in Tyrol/Austria for year of diagnosis 2020
Oberaigner, W., & Geiger-Gritsch, S. (2014) · Wiener klinische Wochenschrift · doi:10.1007/s00508-014-0596-3 · Cited by 8 · see citing works
Liebl, M. E., Preiß, S., Pögel, S., et al. (2014) · Physikalische Medizin Rehabilitationsmedizin Kurortmedizin · doi:10.1055/s-0033-1357157 · Cited by 8 · see citing works
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CAMPBELL, K. L., WINTERS-STONE, K. M., WISKEMANN, J., MAY, A. M., SCHWARTZ, A. L., COURNEYA, K. S., ZUCKER, D. S., MATTHEWS, C. E., LIGIBEL, J. A., GERBER, L. H., et al. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002116 · Cited by 2,988 · see citing works
Uhm, K. E., Yoo, J. S., Chung, S. H., Lee, J. D., Lee, I., Kim, J. I., Lee, S. K., Nam, S. J., Park, Y. H., Lee, J. Y., et al. (2017) · Breast Cancer Research and Treatment · doi:10.1007/s10549-016-4065-8 · Cited by 175 · see citing works
Olsson Möller, U., Beck, I., Rydén, L., & Malmström, M. (2019) · BMC Cancer · doi:10.1186/s12885-019-5648-7 · Cited by 189 · see citing works
Schulz, S. V. W., Laszlo, R., Otto, S., Prokopchuk, D., Schumann, U., Ebner, F., Huober, J., & Steinacker, J. M. (2018) · Disability and Rehabilitation · doi:10.1080/09638288.2017.1300688 · Cited by 47 · see citing works
- Authors
- Keilani, M., Hasenoehrl, T., Neubauer, M., & Crevenna, R.
- Affiliations
- Medical University of Vienna (AT)
- Corresponding author
- Crevenna, R.
- Venue
- Supportive Care in Cancer
- Published
- 2015-12-30
- Volume
- 24
- Issue
- 4
- Pages
- 1907-1916
- ISSN
- 0941-4355 (ISSN-L)
- 1433-7339
- OpenAlex
- W2211086774
- Cited by
- 93
- References
- 40
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 27 · 2023: 3 · 2022: 8 · 2021: 7 · 2020: 11 · 2019: 10 · 2018: 7 · 2017: 10 · 2016: 4
- FWCI
- 0.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Supportive Care in Cancer (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Lymphatic System and Diseases
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Keywords
- resistance training, secondary lymphedema, breast cancer survivors, exercise safety, cancer rehabilitation
- MeSH terms
- Aged, Breast Neoplasms, Female, Humans, Lymphedema, Middle Aged, Risk Factors, Exercise, Survivors
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