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Cited by 17Coconut Research and ApplicationsNatural Antidiabetic Agents StudiesNatural Products and Biological Research

Antihyperlipidemic effects of mature coconut water and its role in regulating lipid metabolism in alloxan-induced experimental diabetes

Preetha, P. P., Devi, V. Girija, Rajamohan, T.·2014·Comparative Clinical Pathology
DOI 10.1007/s00580-013-1784-7
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Crossref · 10.1007/s00580-013-1784-7

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51 of 51 references verified0 citation errors · 0 not checkable

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  • Coconut water increased insulin levels and liver glycogen concentrations and reduced glycated hemoglobin levels in diabetic rats.

    “Coconut water also increased insulin levels and liver glycogen concentrations and reduced glycated hemoglobin levels in diabetic rats.”

    From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [71]

  • Treatment of diabetic rats with lyophilized mature coconut water (1000 mg/kg body weight) or glibenclamide (0.6 mg/kg body weight) reduced blood glucose levels (129.23±1.95 and 120±2.3 mg/dL, respectively) compared with the untreated control (275.32±4.25 mg/dL).

    “Treatment of diabetic rats with lyophilized mature coconut water (1000 mg/kg body weight) or glibenclamide (0.6 mg/kg body weight) reduced blood glucose levels (129.23±1.95 and 120±2.3 mg/dL, respectively) when compared with the untreated control (275.32±4.25 mg/dL).”

    From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [71]

  • Diabetic rats showed altered levels of blood urea, serum creatinine, and albumin, and the albumin/globulin ratio was significantly reversed by treatment with mature coconut water and glibenclamide.

    “It was also observed that diabetic rats showed altered levels of blood urea, serum creatinine, and albumin, and the albumin/globulin ratio was significantly reversed by treatment with mature coconut water and glibenclamide.”

    From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [71]

  • Elevated levels of liver function enzymes markers like alkaline phosphatase, serum glutamate oxaloacetate transaminase, and serum glutamate pyruvate transaminase in diabetic rats were significantly reduced upon treatment with mature coconut water.

    “In addition, elevated levels of liver function enzymes markers like alkaline phosphatase, serum glutamate oxaloacetate transaminase, and serum glutamate pyruvate transaminase in diabetic rats were significantly reduced upon treatment with mature coconut water.”

    From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [71]

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Authors
Preetha, P. P., Devi, V. G., & Rajamohan, T.
Affiliations
  • University of Kerala (IN)
  • Government of Kerala (IN)
Corresponding author
Rajamohan, T.
ORCID
Preetha, P. P.
Venue
Comparative Clinical Pathology
Publisher
Springer Science and Business Media LLC
Published
2013-07-20
Volume
23
Issue
5
Pages
1331-1337
ISSN
  • 0938-7714 (ISSN-L)
  • 1618-5641
  • 1618-565X
DOI
10.1007/s00580-013-1784-7
OpenAlex
W2137898250
Cited by
17
References
52
Citations by year
2023: 1 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 2
FWCI
0.47
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
Comparative Clinical Pathology (publishedVersion)
Topics
  • Physical Sciences › Chemistry › Inorganic Chemistry › Coconut Research and Applications
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
  • Health Sciences › Medicine › Surgery › Natural Products and Biological Research
Keywords
hypolipidemic effect, hyperlipidemia, experimental diabetes, alloxan-induced diabetes, lipid metabolism, HMG-CoA reductase, lecithin:cholesterol acyltransferase, lipoprotein lipase, atherogenic index, triglycerides, free fatty acids, phospholipids, blood glucose

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