Cited by 193Balance, Gait, and Falls PreventionStroke Rehabilitation and RecoveryParkinson's Disease Mechanisms and Treatments

The DOI matches its Crossref record; 85 of the 86 references it cites were found in a registry or an index.

Treadmill training for the treatment of gait disturbances in people with Parkinson's disease: a mini-review

Herman, T., Giladi, N., Hausdorff, J. M.·2009·Journal of Neural Transmission

DOI 10.1007/s00702-008-0139-z

Open this paper in CoChat — free account

Abstract

This report reviews recent investigations of the effects of treadmill training (TT) on the gait of patients with Parkinson's disease. A literature search identified 14 relevant studies. Three studies reported on the immediate effects of TT; over-ground walking improved (e.g., increased speed and stride length) after one treadmill session. Effects persisted even 15 min later. Eleven longer-term trials demonstrated feasibility, safety and efficacy, reporting positive benefits in gait speed, stride length and other measures such as disease severity (e.g., Unified Parkinson's Disease Rating Scale) and health-related quality of life, even several weeks after cessation of the TT. Long-term carryover effects also raise the possibility that TT may elicit positive neural plastic changes. While encouraging, the work to date is preliminary; none of the identified studies received a quality rating of Gold or level Ia. Additional high quality randomized controlled studies are needed before TT can be recommended with evidence-based support.

Integrity signals

Registry

Crossref · 10.1007/s00702-008-0139-z

Cites

85 of 85 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

Cardiovascular dysautonomia in de novo Parkinson's disease
Oka, H., Mochio, S., Onouchi, K., Morita, M., Yoshioka, M., & Inoue, K. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2005.10.014 · Cited by 68
Retracted
Gait variability and fall risk in community-living older adults: A 1-year prospective study
Hausdorff, J. M., Rios, D. A., & Edelberg, H. K. (2001) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2001.24893 · Cited by 2,408
Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease.
Krack, P., Batir, A., Blercom, N. V., Chabardès, S., Fraix, V., Ardouin, C., Koudsié, A., Limousin, P., Benazzouz, A., LeBas, J., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035275 · Cited by 2,208
Falls and freezing of gait in Parkinson's disease: A review of two interconnected, episodic phenomena
Bloem, B. R., Hausdorff, J. M., Visser, J. E., & Giladi, N. (2004) · Movement Disorders · doi:10.1002/mds.20115 · Cited by 1,298
Gait variability: methods, modeling and meaning
Hausdorff, J. M. (2005) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-2-19 · Cited by 942
Rehabilitation after Stroke
Dobkin, B. H. (2005) · New England Journal of Medicine · doi:10.1056/nejmcp043511 · Cited by 941
Gait variability and basal ganglia disorders: Stride‐to‐stride variations of gait cycle timing in parkinson's disease and Huntington's disease
Hausdorff, J. M., Cudkowicz, M., Firtion, R., Wei, J. Y., & Goldberger, A. L. (1998) · Movement Disorders · doi:10.1002/mds.870130310 · Cited by 897
Prospective assessment of falls in Parkinson's disease
Bloem, B. R., Grimbergen, Y. A. M., Cramer, M., Willemsen, M., & Zwinderman, A. H. (2001) · Journal of Neurology · doi:10.1007/s004150170047 · Cited by 869
Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trial
Nieuwboer, A., Kwakkel, G., Rochester, L., Jones, D., van Wegen, E., Willems, A. M., Chavret, F., Hetherington, V, Baker, K., & Lim, I. (2007) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.200x.097923 · Cited by 857
The pathogenesis of gait hypokinesia in Parkinson's disease
Morris, M. E., Iansek, R., Matyas, T. A., & Summers, J. J. (1994) · Brain · doi:10.1093/brain/117.5.1169 · Cited by 709
The basal ganglia: learning new tricks and loving it
Graybiel, A. M. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.10.006 · Cited by 678
Treadmill Training With Partial Body Weight Support Compared With Physiotherapy in Nonambulatory Hemiparetic Patients
Hesse, S., Bertelt, C., Jahnke, M. T., Schaffrin, A., Baake, P., Maležič, M., & Mauritz, K.-H. (1995) · Stroke · doi:10.1161/01.str.26.6.976 · Cited by 612
Locomotor Training After Human Spinal Cord Injury: A Series of Case Studies
Behrman, A. L., & Harkema, S. J. (2000) · Physical Therapy · doi:10.1093/ptj/80.7.688 · Cited by 597
Increased gait unsteadiness in community-dwelling elderly fallers
Hausdorff, J. M., Edelberg, H. K., Mitchell, S. L., Goldberger, A. L., & Wei, J. Y. (1997) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/s0003-9993(97)90034-4 · Cited by 592
Evidence‐based analysis of physical therapy in Parkinson's disease with recommendations for practice and research
Keus, S. H. J., Bloem, B. R., Hendriks, E., Bredero-Cohen, A. B., Munneke, M., & on behalf of the Practice Recommendations Development Group (2006) · Movement Disorders · doi:10.1002/mds.21244 · Cited by 495
Effects of external rhythmical cueing on gait in patients with Parkinson's disease: a systematic review
Lim, I., van Wegen, E. E. H., de Goede, C. J. T., Deutekom, M. D. L. F., Nieuwboer, A., Willems, A., Jones, D. E., Rochester, L., & Kwakkel, G. (2005) · Clinical Rehabilitation · doi:10.1191/0269215505cr906oa · Cited by 494
Rhythmic auditory stimulation modulates gait variability in Parkinson’s disease
Hausdorff, J. M., Lowenthal, J., Herman, T., Gruendlinger, L., Peretz, C., & Giladi, N. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05810.x · Cited by 489
A functional MRI study of automatic movements in patients with Parkinson's disease
Wu, T., & Hallett, M. (2005) · Brain · doi:10.1093/brain/awh569 · Cited by 483
Intensive voice treatment (LSVT(R)) for patients with Parkinson's disease: a 2 year follow up
Ramig, L. O. (2001) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.71.4.493 · Cited by 481
Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa
Schaafsma, J. D., Giladi, N., Balash, Y., Bartels, A. L., Gurevich, T., & Hausdorff, J. M. (2003) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(03)00104-7 · Cited by 480
The Effect of Exercise Training in Improving Motor Performance and Corticomotor Excitability in People With Early Parkinson's Disease
Fisher, B. E., Wu, A. D., Salem, G. J., Song, J., Lin, C.-H. (., Yip, J., Cen, S., Gordon, J., Jakowec, M., & Petzinger, G. (2008) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2008.01.013 · Cited by 474
Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait
Hausdorff, J. M., Schaafsma, J. D., Balash, Y., Bartels, A. L., Gurevich, T., & Giladi, N. (2003) · Experimental Brain Research · doi:10.1007/s00221-002-1354-8 · Cited by 442
Treadmill walking as an external pacemaker to improve gait rhythm and stability in Parkinson's disease
Frenkel‐Toledo, S., Giladi, N., Peretz, C., Herman, T., Gruendlinger, L., & Hausdorff, J. M. (2005) · Movement Disorders · doi:10.1002/mds.20507 · Cited by 399
Locomotor activity in spinal man
Dietz, V. H., Colombo, G., & Jensen, L. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90751-x · Cited by 397
Quantitative analysis of gait in Parkinson patients: increased variability of stride length
Blin, O. J., Ferrandez, A., & Serratrice, G. (1990) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(90)90184-o · Cited by 378
The power of cueing to circumvent dopamine deficits: A review of physical therapy treatment of gait disturbances in Parkinson's disease
Rubinstein, T. C., Giladi, N., & Hausdorff, J. M. (2002) · Movement Disorders · doi:10.1002/mds.10259 · Cited by 364
Quality of life in patients with Parkinson's disease: development of a questionnaire.
de Boer, A. G. E. M., Wijker, W., Speelman, J. D., & de Haes, J. C. J. M. (1996) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.61.1.70 · Cited by 362
Gait and step training to reduce falls in Parkinson's disease
Protas, E. J., Mitchell, K., Williams, A., Qureshy, H., Caroline, K. S., & Lai, E. C. (2005) · Neurorehabilitation · doi:10.3233/nre-2005-20305 · Cited by 354
Quantitative Gait Analysis in Parkinson’s Disease: Comparison With a Healthy Control Group
Sofuwa, O., Nieuwboer, A., Desloovere, K., Willems, A., Chavret, F., & Jonkers, I. (2005) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2004.08.012 · Cited by 351
Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury
Petzinger, G. M., Walsh, J. P., Akopian, G., Hogg, E., Abernathy, A., Arevalo, P., Turnquist, P., Vučković, M., Fisher, B. E., Togasaki, D. M., et al. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1069-07.2007 · Cited by 329
Effects of walking velocity on vertical head and body movements during locomotion
Hirasaki, E., Moore, S. T., Raphan, T., & Cohen, B. (1999) · Experimental Brain Research · doi:10.1007/s002210050781 · Cited by 326
Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: a pilot study
Herman, T., Giladi, N., Gruendlinger, L., & Hausdorff, J. M. (2007) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2007.05.015 · Cited by 315
Treadmill training with body weight support: Its effect on Parkinson's disease
Miyai, I., Fujimoto, Y., Ueda, Y., Yamamoto, H., 野崎, 園., Saito, T., & Kang, J. K. (2000) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2000.4439 · Cited by 314
Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia
Fisher, B. E., Petzinger, G. M., Nixon, K., Hogg, E., Bremmer, S., Meshul, C. K., & Jakowec, M. W. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20162 · Cited by 311
Mechanisms underlying gait disturbance in Parkinson's disease
Hanakawa, T., Katsumi, Y., Fukuyama, H., Honda, M., Hayashi, T., Kimura, J., & Shibasaki, H. (1999) · Brain · doi:10.1093/brain/122.7.1271 · Cited by 311
Aquatic exercise for the treatment of knee and hip osteoarthritis
Bartels, E. M., Lund, H., Hagen, K. B., Dagfinrud, H., Christensen, R., & Danneskiold-Samsøe, B. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005523.pub2 · Cited by 302
Two‐year follow‐up of subthalamic deep brain stimulation in Parkinson's disease
Herzog, J., Volkmann, J., Krack, P., Kopper, F., Pötter, M., Lorenz, D., Steinbach, M., Klebe, S., Hamel, W., Schrader, B., et al. (2003) · Movement Disorders · doi:10.1002/mds.10518 · Cited by 295
Effect of gait speed on gait rhythmicity in Parkinson's disease: variability of stride time and swing time respond differently
Frenkel-Toledo, S., Giladi, N., Peretz, C., Herman, T., Gruendlinger, L., & Hausdorff, J. M. (2005) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-2-23 · Cited by 285
Long-term effect of body weight-supported treadmill training in Parkinson's disease: a randomized controlled trial
Miyai, I., Fujimoto, Y., Yamamoto, H., Ueda, Y., Saito, T., Nozaki, S., & Kang, J. (2002) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2002.34603 · Cited by 284
Falls in outpatients with Parkinson's disease
Balash, Y., Peretz, C., Leibovich, G., Herman, T., Hausdorff, J. M., & Giladi, N. (2005) · Journal of Neurology · doi:10.1007/s00415-005-0855-3 · Cited by 276
Marked alterations in the gait timing and rhythmicity of patients withde novoParkinson's disease
Baltadjieva, R., Giladi, N., Gruendlinger, L., Peretz, C., & Hausdorff, J. M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05033.x · Cited by 270
Falls in Parkinson's disease
Grimbergen, Y. A. M., Munneke, M., & Bloem, B. R. (2004) · Current Opinion in Neurology · doi:10.1097/01.wco.0000137530.68867.93 · Cited by 268
Relationship between Falls and Stride Length Variability in Senile Dementia of the Alzheimer Type
Nakamura, T., Meguro, K., & Sasaki, H. (2009) · Gerontology · doi:10.1159/000213780 · Cited by 241
Influence of dopaminergic medication on automatic postural responses and balance impairment in Parkinson's disease
Bloem, B. R., Beckley, D. J., van Dijk, J. G., Zwinderman, A. H., Remler, M. P., & Roos, R. A. C. (1996) · Movement Disorders · doi:10.1002/mds.870110506 · Cited by 240
The effects of incremental speed-dependent treadmill training on postural instability and fear of falling in Parkinson's disease
Çakıt, B. D., Saraçoğlu, M., Genç, H., Erdem, H. R., & İnan, L. E. (2007) · Clinical Rehabilitation · doi:10.1177/0269215507077269 · Cited by 229
Neural control of locomotion: sensory control of the central pattern generator and its relation to treadmill training
de Crommert, H. W. A. A. V., Mulder, T., & Duysens, J. (1998) · Gait & Posture · doi:10.1016/s0966-6362(98)00010-1 · Cited by 229
The effects of physical therapy in Parkinson's Disease: A research synthesis
Goede, C. J. T. D., Keus, S. H. J., Kwakkel, G., & Wagenaar, R. C. (2001) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2001.22352 · Cited by 225
Comparative analysis of gait in Parkinson's disease, cerebellar ataxia and subcortical arteriosclerotic encephalopathy
Ebersbach, G., Sojer, M., Valldeoriola, F., Wissel, J., Müller, J., TOLOSA, E. S., & Poewe, W. H. (1999) · Brain · doi:10.1093/brain/122.7.1349 · Cited by 224
Hypophonia in Parkinson’s disease
Mario Liotti, A., Ramig, L. O., Vogel, D., New, P., Cook, C. I., Ingham, R. J., Ingham, J. C., & Fox, P. T. (2003) · Neurology · doi:10.1212/wnl.60.3.432 · Cited by 213
The effect of treadmill training on the ambulation of stroke survivors in the early stages of rehabilitation: a randomized study.
Laufer, Y., Dickstein, R., Chefez, Y., & Marcovitz, E. (2001) · PubMed · Cited by 211
Evidence‐Based Rheumatology
(2003) · Wiley eBooks · doi:10.1002/9781444315844 · Cited by 205
Practice Parameter: Assessing patients in a neurology practice for risk of falls (an evidence-based review)
Thurman, D. J., Stevens, J. A., & Rao, J. K. (2008) · Neurology · doi:10.1212/01.wnl.0000299085.18976.20 · Cited by 201
The Evolution of Walking-Related Outcomes Over the First 12 Weeks of Rehabilitation for Incomplete Traumatic Spinal Cord Injury: The Multicenter Randomized Spinal Cord Injury Locomotor Trial
Dobkin, B. H., Barbeau, H., Deforge, D., Ditunno, J. F., Elashoff, R. E., Apple, D. F., Basso, M., Behrman, A. L., Fugate, L. P., Harkema, S. J., et al. (2006) · Neurorehabilitation and neural repair · doi:10.1177/1545968306295556 · Cited by 196
Physiotherapy versus placebo or no intervention in Parkinson's disease
Tomlinson, C. L., Patel, S., Meek, C., Clarke, C. E., Stowe, R. L., Shah, L., Sackley, C. M., Deane, K. H., Wheatley, K., & Ives, N. J. (2001) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002817 · Cited by 194
Immediate effects of speed-dependent treadmill training on gait parameters in early Parkinson’s disease11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.
Pohl, M., Rockstroh, G., Rückriem, S., Mrass, G., & Mehrholz, J. (2003) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/s0003-9993(03)00433-7 · Cited by 194
An introduction to the concept of “quality of life in Parkinson’s disease”
Martínez‐Martín, P. (1998) · Journal of Neurology · doi:10.1007/pl00007733 · Cited by 194
Effect of chronic bilateral subthalamic nucleus (STN) stimulation on postural control in Parkinson's disease
Maurer, C., Mergner, T., Xie, J., Faist, M., Pollak, P., & Lücking, C. H. (2003) · Brain · doi:10.1093/brain/awg100 · Cited by 188
Parkinson's Disease: Speech and Voice Disorders and Their Treatment with the Lee Silverman Voice Treatment
Ramig, L. O., Fox, C., & Sapir, S. (2004) · Seminars in Speech and Language · doi:10.1055/s-2004-825653 · Cited by 160
Effects of bilateral subthalamic nucleus stimulation on parkinsonian gait
Stolze, H., Klebe, S., Poepping, M., Lorenz, D., Herzog, J., Hamel, W., Schrader, B., Raethjen, J., Wenzelburger, R., Mehdorn, H. M., et al. (2001) · Neurology · doi:10.1212/wnl.57.1.144 · Cited by 143
Treadmill exercise suppresses nigrostriatal dopaminergic neuronal loss in 6-hydroxydopamine-induced Parkinson's rats
Yoon, M.-C., Shin, M., Kim, T.-S., Kim, B.-K., Ko, I., Sung, Y.-H., Kim, S., Lee, H., Kim, Y.-P., & Kim, C. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.06.031 · Cited by 142
Early Abnormalities of Vascular and Cardiac Autonomic Control in Parkinson’s Disease Without Orthostatic Hypotension
Barbic, F., Perego, F., Canesi, M., Gianni, M., Biagiotti, S., Costantino, G., Pezzoli, G., Porta, A., Malliani, A., & Furlan, R. (2006) · Hypertension · doi:10.1161/01.hyp.0000250939.71343.7c · Cited by 140
The effects of loading and unloading treadmill walking on balance, gait, fall risk, and daily function in Parkinsonism
Toole, T., Maitland, C., Warren, E., Hubmann, M. F., & Panton, L. B. (2005) · Neurorehabilitation · doi:10.3233/nre-2005-20406 · Cited by 134
Centrally Initiated Postural Adjustments in Parkinsonian Patients On and Off Levodopa
Frank, J. S., Horak, F. B., & Nutt, J. G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.5.2440 · Cited by 130
Motor Behavior Research: Implications for Therapeutic Approaches to Central Nervous System Dysfunction
Mathiowetz, V. G., & Haugen, J. D. B. (1994) · American Journal of Occupational Therapy · doi:10.5014/ajot.48.8.733 · Cited by 124
Sensorimotor stimulation to improve locomotor recovery after spinal cord injury
Muir, G. D., & Steeves, J. D. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10068-0 · Cited by 122
Systematic review of paramedical therapies for Parkinson's disease
Deane, K. H., Ellis‐Hill, C., Jones, D. E., Whurr, R., Ben‐Shlomo, Y., Playford, E. D., & Clarke, C. E. (2002) · Movement Disorders · doi:10.1002/mds.10197 · Cited by 112
Preserved Implicit Learning on Both the Serial Reaction Time Task and Artificial Grammar in Patients with Parkinson's Disease
Smith, J. G., Siegert, R. J., McDowall, J., & Abernethy, D. A. (2001) · Brain and Cognition · doi:10.1006/brcg.2001.1286 · Cited by 107
Improvement of voicing in patients with Parkinson’s disease by speech therapy
Swart, B. J. M. D., Willemse, S. C., Maassen, B., & Horstink, M. W. I. M. (2003) · Neurology · doi:10.1212/01.wnl.0000044480.95458.56 · Cited by 102
Physiotherapy for Parkinson's disease: a comparison of techniques
Deane, K. H., Jones, D. E., Ellis‐Hill, C., Clarke, C. E., Playford, E. D., & Ben‐Shlomo, Y. (2001) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002815 · Cited by 102
Effects of Parkinson Disease on Two Putative Nondeclarative Learning Tasks
Perretta, J. G., Pari, G., & Beninger, R. J. (2005) · Cognitive and Behavioral Neurology · doi:10.1097/01.wnn.0000187939.81541.1d · Cited by 101
Does Treadmill Training Improve Lower-Extremity Tasks in Parkinson Disease? A Randomized Controlled Trial
Kurtaiş, Y., Kutlay, Ş., Tur, B. S., Gök, H., & Akbostancı, C. (2008) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0b013e318170626d · Cited by 98
Towards an explicit account of implicit learning
Forkstam, C., & Petersson, K. M. (2005) · Current Opinion in Neurology · doi:10.1097/01.wco.0000171951.82995.c4 · Cited by 97
Treadmill walking in Parkinson's disease patients: Adaptation and generalization effect
Bello, O., Sánchez, J. A., & Fernández‐del‐Olmo, M. (2008) · Movement Disorders · doi:10.1002/mds.22069 · Cited by 76
Deep brain stimulation effect on freezing of gait
Ferraye, M., Debû, B., & Pollak, P. (2008) · Movement Disorders · doi:10.1002/mds.21975 · Cited by 70
Cardiovascular Response to Treadmill Testing in Parkinson Disease
Werner, W. G., DiFrancisco‐Donoghue, J., & Lamberg, E. M. (2006) · Neurology Report · doi:10.1097/01.npt.0000282570.78544.00 · Cited by 63
Pilot safety and feasibility study of treadmill aerobic exercise in Parkinson disease with gait impairment
Skidmore, F. M. (2008) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2006.10.0130 · Cited by 60
The relationship between knowledge of results and motor learning in Parkinsonian patients
Guadagnoli, M. A., Leis, B. C., Gemmert, A. W. A. V., & Stelmach, G. E. (2002) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(02)00007-x · Cited by 50
Learning of ambiguous versus hybrid sequences by patients with Parkinson’s disease
Kelly, S. W., Jahanshahi, M., & Dirnberger, G. (2004) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2004.02.013 · Cited by 43
Parkinsonian patients report blunted subjective effects of methylphenidate.
Persico, A. M., Reich, S., Henningfield, J. E., Kuhar, M. J., & Uhl, G. R. (1998) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.6.1.54 · Cited by 30
Learning a high‐precision locomotor task in patients with Parkinson's disease
van Hedel, H. J. A., Waldvogel, D., & Dietz, V. (2005) · Movement Disorders · doi:10.1002/mds.20710 · Cited by 26
Clinical correlates of motor performance during paced postural tasks in Parkinson's disease
Beckley, D. J., Panzer, V. P., Remler, M. P., Ilog, L. B., & Bloem, B. R. (1995) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(95)00130-t · Cited by 25
Improvement of voicing in patients with Parkinson’s disease by speech therapy
Liotti, M., & Ramig, L. O. (2003) · Neurology · doi:10.1212/wnl.61.9.1316 · Cited by 11
Letter to the Editor. Discussion: Improvement of voicing in patients with Parkinson's disease by speech therapy.
Swart, B. J. M. D., Willemse, S. C., Maassen, B., & Horstink, M. W. I. M. (2003) · Radboud Repository (Radboud University) · Cited by 5
Treadmill training improves functional ability and cardiopulmonary capacity in stable Parkinson's Disease
Pelosin, E., Faelli, E. L., Lofrano, F., Marinelli, L., Bove, M., Ruggeri, P., & Abbruzzese, G. (2007) · CINECA IRIS Institutial Research Information System (University of Genoa) · Cited by 2
Untitled work
(2001) · doi:10.1002/1531-8257(200101)16:1

Research works printed but not linked: 1

Canning CG, Allen NE, Fung VSC, Morris JGL, Dean CM (2008) Home-based treadmill walking for individuals with Parkinson’s disease: a pilot randomized controlled trial. Mov Disord 23:S210

Sorted by citations

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease
Petzinger, G. M., Fisher, B. E., McEwen, S., Beeler, J. A., Walsh, J. P., & Jakowec, M. W. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70123-6 · Cited by 798
Gait dynamics in Parkinson’s disease: Common and distinct behavior among stride length, gait variability, and fractal-like scaling
Hausdorff, J. M. (2009) · Chaos An Interdisciplinary Journal of Nonlinear Science · doi:10.1063/1.3147408 · Cited by 633
Randomized Clinical Trial of 3 Types of Physical Exercise for Patients With Parkinson Disease
Shulman, L. M., Katzel, L. I., Ivey, F. M., Sorkin, J. D., Favors, K., Anderson, K. E., Smith, B. A., Reich, S. G., Weiner, W. J., & Macko, R. F. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.646 · Cited by 410
“A random number generator allocated eligible participants into 1 of 3 exercise groups in a 1:1:1 ratio: (1) higher-intensity treadmill, (2) lower-intensity treadmill, or (3) stretching and resistance.”
BackgroundMethodInfluential
Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review
Paillard, T., Rolland, Y., & Barreto, P. D. S. (2015) · Journal of Clinical Neurology · doi:10.3988/jcn.2015.11.3.212 · Cited by 397
Summary of the recommendations of the EFNS / MDS ‐ ES review on therapeutic management of P arkinson's disease
Ferreira, J. J., Katzenschlager, R., Bloem, B. R., Bonuccelli, U., Burn, D. J., Deuschl, G., Dietrichs, E., Fabbrini, G., Friedman, A., Kaňovský, P., et al. (2012) · European Journal of Neurology · doi:10.1111/j.1468-1331.2012.03866.x · Cited by 359

See all 193

Authors: Herman, T., Giladi, N., & Hausdorff, J. M.
Affiliations: Tel Aviv Sourasky Medical Center (IL)
Tel Aviv University (IL)
Harvard University (US)
Corresponding author: Hausdorff, J. M.
ORCID: Herman, T.
Giladi, N.
Hausdorff, J. M.
Venue: Journal of Neural Transmission
Publisher: Springer Science and Business Media LLC
Published: 2008-11-04
Volume: 116
Issue: 3
Pages: 307-318
ISSN: 0300-9564 (ISSN-L)
1435-1463
DOI: 10.1007/s00702-008-0139-z
OpenAlex: W2101329822
Cited by: 193
References: 86
Citations by year: 2026: 3 · 2025: 3 · 2024: 14 · 2023: 8 · 2022: 5 · 2021: 6 · 2020: 10 · 2019: 11 · 2018: 12 · 2017: 10 · 2016: 13 · 2015: 18 · 2014: 18 · 2013: 15 · 2012: 16
FWCI: 1.40
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Journal of Neural Transmission (publishedVersion)
PubMed (publishedVersion)
Funders: European Commission
National Institutes of Health
National Institute on Aging (AG 14100)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Keywords: treadmill training, Parkinson's disease, gait disturbance, walking speed, stride length, residual effects, neuroplasticity, health-related quality of life, exercise therapy
MeSH terms: Clinical Trials as Topic, Exercise Therapy, Gait, Humans, Parkinson Disease, Quality of Life, Severity of Illness Index, Time Factors, Treatment Outcome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Treadmill training for the treatment of gait disturbances in people with Parkinson's disease: a mini-review

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks