Cited by 193Balance, Gait, and Falls PreventionStroke Rehabilitation and RecoveryParkinson's Disease Mechanisms and Treatments

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Treadmill training for the treatment of gait disturbances in people with Parkinson's disease: a mini-review

Herman, T., Giladi, N., Hausdorff, J. M.·2009·Journal of Neural Transmission

DOI 10.1007/s00702-008-0139-z

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Abstract

This report reviews recent investigations of the effects of treadmill training (TT) on the gait of patients with Parkinson's disease. A literature search identified 14 relevant studies. Three studies reported on the immediate effects of TT; over-ground walking improved (e.g., increased speed and stride length) after one treadmill session. Effects persisted even 15 min later. Eleven longer-term trials demonstrated feasibility, safety and efficacy, reporting positive benefits in gait speed, stride length and other measures such as disease severity (e.g., Unified Parkinson's Disease Rating Scale) and health-related quality of life, even several weeks after cessation of the TT. Long-term carryover effects also raise the possibility that TT may elicit positive neural plastic changes. While encouraging, the work to date is preliminary; none of the identified studies received a quality rating of Gold or level Ia. Additional high quality randomized controlled studies are needed before TT can be recommended with evidence-based support.

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Authors: Herman, T., Giladi, N., & Hausdorff, J. M.
Affiliations: Tel Aviv Sourasky Medical Center (IL)
Tel Aviv University (IL)
Harvard University (US)
Corresponding author: Hausdorff, J. M.
ORCID: Herman, T.
Giladi, N.
Hausdorff, J. M.
Venue: Journal of Neural Transmission
Publisher: Springer Science and Business Media LLC
Published: 2008-11-04
Volume: 116
Issue: 3
Pages: 307-318
ISSN: 0300-9564 (ISSN-L)
1435-1463
DOI: 10.1007/s00702-008-0139-z
OpenAlex: W2101329822
Cited by: 193
References: 86
Citations by year: 2026: 3 · 2025: 3 · 2024: 14 · 2023: 8 · 2022: 5 · 2021: 6 · 2020: 10 · 2019: 11 · 2018: 12 · 2017: 10 · 2016: 13 · 2015: 18 · 2014: 18 · 2013: 15 · 2012: 16
FWCI: 1.40
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Journal of Neural Transmission (publishedVersion)
PubMed (publishedVersion)
Funders: European Commission
National Institutes of Health
National Institute on Aging (AG 14100)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Keywords: treadmill training, Parkinson's disease, gait disturbance, walking speed, stride length, residual effects, neuroplasticity, health-related quality of life, exercise therapy
MeSH terms: Clinical Trials as Topic, Exercise Therapy, Gait, Humans, Parkinson Disease, Quality of Life, Severity of Illness Index, Time Factors, Treatment Outcome

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Treadmill training for the treatment of gait disturbances in people with Parkinson's disease: a mini-review

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