Cited by 225Balance, Gait, and Falls PreventionParkinson's Disease Mechanisms and TreatmentsStroke Rehabilitation and Recovery

The effects of physical therapy in Parkinson's Disease: A research synthesis

Goede, Cees J.T.de, Keus, Samyra H.J., Kwakkel, Gert, Wagenaar, Robert C.·2001·Archives of Physical Medicine and Rehabilitation

Abstract

Objective To present a critical review and meta-analysis of studies evaluating the effects of physical therapy in patients suffering from Parkinson's disease (PD), in terms of neurologic signs, activities of daily living (ADLs), and walking ability.Data sources Articles published from 1966 to May 1999 were compiled by means of MEDLINE, Cochrane register of controlled trials, and CINAHL using combinations of the key words Parkinson's disease, exercise, exercise therapy, physical therapy, and group training. References presented in relevant publications were also examined. Articles written in English, German, or Dutch were included.Study selection Studies had to meet the following selection criteria: (1) patients with PD were included in the intervention study, (2) the effects of physical therapy (PT) were evaluated, (3) the study could be classified as true or quasi-experiment, and (4) the study was published in a journal or book.Data extraction Two reviewers assessed independently the methodologic quality of the data of each included study. One reviewer extracted relevant meta-analysis data.Data synthesis For each outcome measure the estimated effect size and the summary effect size (SES) were calculated, using fixed (ie, Hedges's g) and random effects models. The meta-analysis resulted in a significant homogeneous SES with regard to ADLs (.40; confidence interval [CI] = .17-.64) and stride length (.46; CI = .12-.82). The SES with regard to walking speed showed a significant heterogeneous SES, which remained significant after applying a random effects model (.49; CI = .21-.77). The SES with regard to neurologic signs was not significant (.22; CI = -.08 to .52). The small number of studies included and the shortcomings of the methodologic quality of these studies, however, bias the results of the present study.Conclusions The results of the present research synthesis support the hypothesis that Parkinson patients benefit from PT added to their standard medication.

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Crossref · 10.1053/apmr.2001.22352

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Authors
Goede, C. J. T. D., Keus, S. H. J., Kwakkel, G., & Wagenaar, R. C.
Affiliations
Boston University (US)
Venue
Archives of Physical Medicine and Rehabilitation
Publisher
Elsevier BV
Published
2001-04
Volume
82
Issue
4
Pages
509-515
ISSN
0003-9993 (ISSN-L)
OpenAlex
W2151400757
Cited by
225
References
33
Citations by year
2025: 3 · 2024: 1 · 2023: 1 · 2021: 3 · 2020: 3 · 2019: 6 · 2018: 7 · 2017: 5 · 2016: 5 · 2015: 10 · 2014: 11 · 2013: 20 · 2012: 7
FWCI
3.67
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Physical Medicine and Rehabilitation (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (submittedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Keywords
Parkinson's disease, physiotherapy, exercise therapy, activities of daily living, walking speed, stride length, gait, motor symptoms, group training
MeSH terms
Activities of Daily Living, Exercise Therapy, Humans, Parkinson Disease, Walking, Physical Therapy Modalities

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