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Cited by 658

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Regulation of Reactive Oxygen Species Generation in Cell Signaling

Open access
Bae, Yun Soo, Oh, Hyunjin, Rhee, Sue Goo, Yoo, Young Do·2011·Molecules and Cells
DOI 10.1007/s10059-011-0276-3
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Abstract

Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H(2)O(2)) are thought to be byproducts of aerobic respiration with damaging effects on DNA, protein, and lipid. A growing body of evidence indicates, however, that ROS are involved in the maintenance of redox homeostasis and various cellular signaling pathways. ROS are generated from diverse sources including mitochondrial respiratory chain, enzymatic activation of cytochrome p450, and NADPH oxidases further suggesting involvement in a complex array of cellular processes. This review summarizes the production and function of ROS. In particular, how cytosolic and membrane proteins regulate ROS generation for intracellular redox signaling will be detailed.

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Metadata

Authors
Bae, Y. S., Oh, H., Rhee, S. G., & Yoo, Y. D.
Venue
Molecules and Cells
Publisher
Elsevier BV
Published
2011-12
Volume
32
Issue
6
Pages
491-509
ISSN
  • 0219-1032 (ISSN-L)
  • 1016-8478
DOI
10.1007/s10059-011-0276-3
OpenAlex
W2119316269
Cited by
658
References
40
FWCI
11.87
Type
journal article
Language
en
Open access
hybrid

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.