CoChat
Sign Up
Cited by 115Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic ControlVestibular and auditory disorders

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Influence of age and gender on the occurrence and presentation of reflex syncope

Romme, Jacobus J. C. M., van Dijk, Nynke, Boer, Kimberly R., Dekker, Lukas R. C., Stam, Jan, Reitsma, Johannes B., Wieling, Wouter·2008·Clinical Autonomic Research
DOI 10.1007/s10286-008-0465-0
Open this paper in CoChat — free account

Abstract

Background The clinical history is the cornerstone of diagnosing patients with transient loss of consciousness (TLOC). Reflex syncope is the most common cause of TLOC in patients across all ages. Knowledge of the variation in incidence and clinical features of reflex syncope by age and gender provides important background information to acquire an accurate diagnosis.Methods In a cohort of 503 patients presenting with TLOC we established a final diagnosis after systematic evaluation and two years of follow-up. The occurrence of prodromal signs, symptoms, and triggers in patients with reflex syncope was analyzed by both age (< 40 yrs, 40-59 yrs and > or = 60 years) and gender.Results Reflex syncope was the most frequently obtained diagnosis (60.2%) in patients of all ages presenting with TLOC. Its occurrence was higher in patients under 40 years (73.4%), than above 60 years of age (45.3%). Pallor (79.9%), dizziness (73.4%), and diaphoresis (63.0%) were the most frequently reported prodromal signs and symptoms. Most triggers and prodromal signs and symptoms were more common in patients under 40 years of age and in women.Conclusions Reflex syncope is nearly twice as common in patients under 40 years of age than in patients aged 60 years or above. Typical signs and symptoms of reflex syncope are more common in younger patients and in women. Therefore, age and gender provide important diagnostic information and can help to decide whether additional testing is necessary.

Overview

Integrity signals

Registry

Crossref · 10.1007/s10286-008-0465-0

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 39 references

Cited by

Sorted by citations

Items 101–115 of 115

Related

See all

Metadata

Authors
Romme, J. J. C. M., van Dijk, N., Boer, K. R., Dekker, L. R. C., Stam, J., Reitsma, J. B., & Wieling, W.
Affiliations
Amsterdam UMC Location University of Amsterdam (NL)
Corresponding author
Romme, Jacobus J. C. M.
ORCID
Venue
Clinical Autonomic Research
Publisher
Springer Science and Business Media LLC
Published
2008-04-30
Volume
18
Issue
3
Pages
127-133
ISSN
  • 0959-9851 (ISSN-L)
  • 1619-1560
DOI
10.1007/s10286-008-0465-0
OpenAlex
W2155882327
Cited by
115
References
39
Citations by year
2026: 2 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 15 · 2021: 9 · 2020: 5 · 2019: 4 · 2018: 8 · 2017: 4 · 2016: 4 · 2015: 6 · 2014: 10 · 2013: 6 · 2012: 5
FWCI
9.84
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Clinical Autonomic Research (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • TU/e Research Portal (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
Keywords
reflex syncope, transient loss of consciousness, age differences, gender differences, prodromal symptoms, syncope triggers, pallor, dizziness, diaphoresis, syncope diagnosis
MeSH terms
Adult, Age Factors, Aged, Diagnosis, Differential, Epilepsy, Female, Follow-Up Studies, Humans, Male, Middle Aged, Sex Factors, Syncope, Cohort Studies, Incidence, Multivariate Analysis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review