Improved conversion efficiencies for n-fatty acid reduction to primary alcohols by the solventogenic acetogen “Clostridium ragsdalei.”
Open accessAbstract
"Clostridium ragsdalei" is an acetogen that ferments synthesis gas (syngas, predominantly H2:CO2:CO) to ethanol, acetate, and cell mass. Previous research showed that C. ragsdalei could also convert propionic acid to 1-propanol and butyric acid to 1-butanol at conversion efficiencies of 72.3 and 21.0 percent, respectively. Our research showed that C. ragsdalei can also reduce pentanoic and hexanoic acid to the corresponding primary alcohols. This reduction occurred independently of growth in an optimized medium with headspace gas exchange (vented and gassed with CO) every 48 h. Under these conditions, conversion efficiencies increased to 97 and 100 % for propionic and butyric acid, respectively. The conversion efficiencies for pentanoic and hexanoic acid to 1-pentanol and 1-hexanol, respectively, were 82 and 62 %. C. ragsdalei also reduced acetone to 2-propanol at a conversion efficiency of 100 %. Further, we showed that C. ragsdalei uses an aldehyde oxidoreductase-like enzyme to reduce n-fatty acids to the aldehyde intermediates in a reaction that requires ferredoxin and exogenous CO.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Pure cultures of C. ljungdahlii and "C. ragsdalei" have been reported to convert externally added carboxylic acids (acetate, propionate, n-butyrate, iso-butyrate, n-valerate, and n-caproate) into their corresponding alcohols using syngas as the source of electrons.
“Pure cultures of C. ljungdahlii and “C. ragsdalei” have been reported to convert externally added carboxylic acids (acetate, propionate, n-butyrate, iso-butyrate, n-valerate, and n-caproate) into their corresponding alcohols using syngas as the source of electrons (Perez et al., 2013; Isom et al., 2015).”
From Gas Fermentation—A Flexible Platform for Commercial Scale Production of Low-Carbon-Fuels and Chemicals from Waste and Renewable Feedstocks (2016) · cites this paper as Isom et al., 2015
"C. ragsdalei" can convert caproate at 62%, valerate at 82%, and butyrate at 100% efficiency to their respective alcohols.
“Isom et al. for example, showed “C. ragsdalei” can convert caproate at 62%, valerate at 82%, and butyrate at 100% efficiency to their respective alcohols.”
From Gas Fermentation—A Flexible Platform for Commercial Scale Production of Low-Carbon-Fuels and Chemicals from Waste and Renewable Feedstocks (2016) · cites this paper as Isom et al., 2015
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works
Energy conservation in chemotrophic anaerobic bacteria
Thauer, R. K., Jungermann, K., & Decker, K. (1977) · Bacteriological Reviews · doi:10.1128/br.41.1.100-180.1977 · Cited by 4,146 · see citing works
Engineering the third wave of biocatalysis
Bornscheuer, U. T., Huisman, G. W., Kazlauskas, R. J., Lutz, S., Moore, J. C., & Robins, K. T. (2012) · Nature · doi:10.1038/nature11117 · Cited by 2,649 · see citing works
Energy Information Administration
Office Of Coal, Fuels, A., Johnson, M. M., Nonutility, U. S., Fuels, S., & Rucker, B. (2007) · Choice Reviews Online · doi:10.5860/choice.44-3624 · Cited by 2,490 · see citing works
Beneficial biofuels—the food, energy, and environment trilemma
Tilman, D., Socolow, R., Foley, J. A., Hill, J., Larson, E., Lynd, L., Pacala, S., Reilly, J., Searchinger, T., Somerville, C., et al. (2009) · Science · doi:10.1126/science.1177970 · Cited by 1,596 · see citing works
Manual of environmental microbiology.
Hurst, C. J., Crawford, R. L., Garland, J. L., Lipson, D. A., Mills, A., & Stetzenbach, L. D. (2007) · Cited by 1,413 · see citing works
Balch, W. E., & WOLFE, R. S. (1976) · Applied and Environmental Microbiology · doi:10.1128/aem.32.6.781-791.1976 · Cited by 919 · see citing works
CDD: conserved domains and protein three-dimensional structure
Marchler‐Bauer, A., Zheng, C., Chitsaz, F., Derbyshire, M. K., Geer, L. Y., Geer, R. C., Gonzales, N. R., Gwadz, M., Hurwitz, D. I., Lanczycki, C. J., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1243 · Cited by 872 · see citing works
<i>Clostridium ljungdahlii</i> represents a microbial production platform based on syngas
Köpke, M., Held, C., Hujer, S., Liesegang, H., Wiezer, A., Wollherr, A., Ehrenreich, A., Liebl, W., Gottschalk, G., & Dürre, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004716107 · Cited by 660 · see citing works
IMG 4 version of the integrated microbial genomes comparative analysis system
Markowitz, V. M., Chen, I.-M. A., Palaniappan, K., Chu, K., Szeto, E., Pillay, M., Ratner, A., Huang, J., Woyke, T., Huntemann, M., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt963 · Cited by 546 · see citing works
Microbiology of synthesis gas fermentation for biofuel production
Henstra, A. M., Sipma, J., Rinzema, A., & Stams, A. J. M. (2007) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2007.03.008 · Cited by 449 · see citing works
Solubility of Paracetamol in Pure Solvents
Granberg, R. A., & Rasmuson, Å. C. (1999) · Journal of Chemical & Engineering Data · doi:10.1021/je990124v · Cited by 384 · see citing works
Liou, J. S.-C., Balkwill, D. L., Drake, G. R., & Tanner, R. S. (2005) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.63482-0 · Cited by 317 · see citing works
The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum )
Pierce, E., Xie, G. G., Barabote, R. D., Saunders, E. H., Han, C. S., Detter, J. C., Richardson, P., Brettin, T. S., Das, A., Ljungdahl, L. G., et al. (2008) · Environmental Microbiology · doi:10.1111/j.1462-2920.2008.01679.x · Cited by 267 · see citing works
Drake, H. L., Küsel, K., & Matthies, C. (2006) · Springer eBooks · doi:10.1007/0-387-30742-7_13 · Cited by 225 · see citing works
Steinbusch, K. J. J., Hamelers, H. V. M., & Buisman, C. J. N. (2008) · Water Research · doi:10.1016/j.watres.2008.05.032 · Cited by 190 · see citing works
Cultivation of Bacteria and Fungi
Tanner, R. S. (2007) · Wiley eBooks · doi:10.1128/9781555815882.ch6 · Cited by 184 · see citing works
Saxena, J., & Tanner, R. S. (2010) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-010-0794-6 · Cited by 153 · see citing works
Bruant, G., Lévesque, M.-J., Peter, C., Guiot, S. R., & Masson, L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013033 · Cited by 139 · see citing works
Studies on the substrate range of Clostridium kluyveri; the use of propanol and succinate
Kenealy, W. R., & Waselefsky, D. M. (1985) · Archives of Microbiology · doi:10.1007/bf00408056 · Cited by 132 · see citing works
Perez, J. M., Richter, H., Loftus, S. E., & Angenent, L. T. (2013) · Biotechnology and Bioengineering · doi:10.1002/bit.24786 · Cited by 126 · see citing works
Key World Energy Statistics 2010
International Energy Agency (2010) · Key world energy statistics ... · doi:10.1787/9789264095243-en · Cited by 124 · see citing works
Wang, S., Zhang, Y., Dong, H., Mao, S., Zhu, Y., Wang, R., Luan, G., & Li, Y. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.01835-10 · Cited by 122 · see citing works
Mixed culture syngas fermentation and conversion of carboxylic acids into alcohols
Liu, K., Atiyeh, H. K., Stevenson, B. S., Tanner, R. S., Wilkins, M. R., & Huhnke, R. L. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.11.015 · Cited by 113 · see citing works
Allen, T. D., Caldwell, M. E., Lawson, P. A., Huhnke, R. L., & Tanner, R. S. (2009) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.018507-0 · Cited by 88 · see citing works
A simple hydrogenase-linked assay for ferredoxin and flavodoxin
Chen, J.-S., & Blanchard, D. K. (1979) · Analytical Biochemistry · doi:10.1016/s0003-2697(79)80140-2 · Cited by 78 · see citing works
Steinbusch, K. J. J., Arvaniti, E., Hamelers, H. V. M., & Buisman, C. J. N. (2009) · Bioresource Technology · doi:10.1016/j.biortech.2009.01.049 · Cited by 75 · see citing works
Synthetic fuel production costs by means of solid oxide electrolysis cells
Skov, I. R., Mathiesen, B. V., & Connolly, D. E. (2014) · Energy · doi:10.1016/j.energy.2014.04.002 · Cited by 63 · see citing works
STROBL, G., Feicht, R., White, H., Lottspeich, F., & Simon, H. (1992) · Biological Chemistry Hoppe-Seyler · doi:10.1515/bchm3.1992.373.1.123 · Cited by 49 · see citing works
On a reversible molybdenum-containing aldehyde oxidoreductase from Clostridium formicoaceticum
White, H., Huber, C., Feicht, R., & Simon, H. (1993) · Archives of Microbiology · doi:10.1007/bf00248479 · Cited by 48 · see citing works
Fraisse, L., & Simon, H. (1988) · Archives of Microbiology · doi:10.1007/bf00408311 · Cited by 45 · see citing works
Autotrophic acetyl coenzyme A biosynthesis in Methanococcus maripaludis
Shieh, J.-S., & Whitman, W. B. (1988) · Journal of Bacteriology · doi:10.1128/jb.170.7.3072-3079.1988 · Cited by 42 · see citing works
Kass, R., & Wakefield, G. (1983) · doi:10.2172/5908783 · Cited by 41 · see citing works
Reduction of acetone to isopropanol using producer gas fermenting microbes
Ramachandriya, K. D., Wilkins, M. R., Delorme, M., Zhu, X., Kundiyana, D. K., Atiyeh, H. K., & Huhnke, R. L. (2011) · Biotechnology and Bioengineering · doi:10.1002/bit.23203 · Cited by 39 · see citing works
Husemann, M. H., & Papoutsakis, E. T. (1990) · Applied and Environmental Microbiology · doi:10.1128/aem.56.5.1497-1500.1990 · Cited by 38 · see citing works
Simon, H., White, H., Lebertz, H., & Thanos, I. C. G. (1987) · Angewandte Chemie International Edition in English · doi:10.1002/anie.198707851 · Cited by 33 · see citing works
Edin, K.-A. (1997) · Energy Policy · doi:10.1016/s0301-4215(97)00053-0 · Cited by 22 · see citing works
Flagged first, then by citations
1 of the 38 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Technical photosynthesis involving CO2 electrolysis and fermentation
Haas, T., Krause, R., Weber, R., Demler, M., & Schmid, G. (2018) · Nature Catalysis · doi:10.1038/s41929-017-0005-1 · Cited by 649 · see citing works
Liew, F., Martin, M. E., Tappel, R. C., Heijstra, B. D., Mihalcea, C., & Köpke, M. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00694 · Cited by 485 · see citing works
Metabolic engineering of Clostridium autoethanogenum for selective alcohol production
Liew, F. E., Henstra, A. M., Köpke, M., Winzer, K., Simpson, S. D., & Minton, N. P. (2017) · Metabolic Engineering · doi:10.1016/j.ymben.2017.01.007 · Cited by 239 · see citing works
Syngas fermentation process development for production of biofuels and chemicals: A review
Sun, X., Atiyeh, H. K., Huhnke, R. L., & Tanner, R. S. (2019) · Bioresource Technology Reports · doi:10.1016/j.biteb.2019.100279 · Cited by 212 · see citing works
Syngas Fermentation: A Microbial Conversion Process of Gaseous Substrates to Various Products
Phillips, J. R., Huhnke, R. L., & Atiyeh, H. K. (2017) · Fermentation · doi:10.3390/fermentation3020028 · Cited by 187 · see citing works
Bacterial Anaerobic Synthesis Gas (Syngas) and CO 2 + H 2 Fermentation
Bengelsdorf, F. R., Beck, M. H., Erz, C., Hoffmeister, S., Karl, M. M., Riegler, P., Wirth, S., Poehlein, A., Weuster‐Botz, D., & Dürre, P. (2018) · Advances in applied microbiology · doi:10.1016/bs.aambs.2018.01.002 · Cited by 164 · see citing works
Biological caproate production by Clostridium kluyveri from ethanol and acetate as carbon sources
Yin, Y., Zhang, Y., Karakashev, D. B., Wang, J., & Angelidaki, İ. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.05.184 · Cited by 148 · see citing works
Fernández‐Naveira, Á., Veiga, M. C., & Kennes, C. (2017) · Journal of Chemical Technology & Biotechnology · doi:10.1002/jctb.5194 · Cited by 143 · see citing works
Industrial Acetogenic Biocatalysts: A Comparative Metabolic and Genomic Analysis
Bengelsdorf, F. R., Poehlein, A., Linder, S., Erz, C., Hummel, T., Hoffmeister, S., Daniel, R., & Dürre, P. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01036 · Cited by 112 · see citing works
Traits of selected Clostridium strains for syngas fermentation to ethanol
Martin, M. E., Richter, H., Saha, S., & Angenent, L. T. (2015) · Biotechnology and Bioengineering · doi:10.1002/bit.25827 · Cited by 111 · see citing works
Wu, L., Wei, W., Song, L., Woźniak-Karczewska, M., Chrzanowski, Ł., & Ni, B. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111448 · Cited by 109 · see citing works
Ammam, F., Tremblay, P., Lizak, D. M., & Zhang, T. (2016) · Biotechnology for Biofuels · doi:10.1186/s13068-016-0576-0 · Cited by 88 · see citing works
Ciliberti, C., Biundo, A., Albergo, R., Agrimi, G., Braccio, G., Bari, I. D., & Pisano, I. (2020) · Processes · doi:10.3390/pr8121567 · Cited by 82 · see citing works
Impact of cyclic pH shifts on carbon monoxide fermentation to ethanol by Clostridium autoethanogenum
Abubackar, H. N., Fernández‐Naveira, Á., Veiga, M. C., & Kennes, C. (2016) · Fuel · doi:10.1016/j.fuel.2016.03.048 · Cited by 73 · see citing works
Abubackar, H. N., Bengelsdorf, F. R., Dürre, P., Veiga, M. C., & Kennes, C. (2016) · Applied Energy · doi:10.1016/j.apenergy.2016.02.021 · Cited by 72 · see citing works
Vees, C. A., Neuendorf, C. S., & Pflügl, S. (2020) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-020-02296-2 · Cited by 65 · see citing works
Butanol formation from gaseous substrates
Dürre, P. (2016) · FEMS Microbiology Letters · doi:10.1093/femsle/fnw040 · Cited by 58 · see citing works
Poehlein, A., Zeldes, B. M., Flaiz, M., Böer, T., Lüschen, A., Höfele, F., Baur, K. S., Molitor, B., Kröly, C., Wang, M., et al. (2024) · Bioresource Technology · doi:10.1016/j.biortech.2024.131913 · Cited by 51 · see citing works
Syngas Biorefinery and Syngas Utilization
Tissera, S. L. D., Köpke, M., Simpson, S. D., Humphreys, C. M., Minton, N. P., & Dürre, P. (2017) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2017_5 · Cited by 50 · see citing works
The emerging role of aldehyde:ferredoxin oxidoreductases in microbially-catalyzed alcohol production
Nissen, L. S., & Basen, M. (2019) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2019.09.005 · Cited by 40 · see citing works
Schulz, S., Molitor, B., & Angenent, L. T. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.128387 · Cited by 36 · see citing works
Harnessing acetogenic bacteria for one-carbon valorization toward sustainable chemical production
Bae, J., Park, C., Jung, H.-W., Jin, S., & Cho, B. (2024) · RSC Chemical Biology · doi:10.1039/d4cb00099d · Cited by 31 · see citing works
Thulluru, L. P., Ghangrekar, M. M., & Chowdhury, S. (2023) · Journal of Environmental Management · doi:10.1016/j.jenvman.2023.117323 · Cited by 31 · see citing works
Hitschler, L., Kuntz, M. A., Langschied, F., & Basen, M. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9210-3 · Cited by 29 · see citing works
Huang, C., Wang, W., Sun, X., Shen, J., & Wang, L. (2019) · Journal of Environmental Management · doi:10.1016/j.jenvman.2019.109842 · Cited by 28 · see citing works
El-Gammal, M. I., Abou-Shanab, R. A. I., Angelidaki, İ., Omar, B. M., Sveding, P. V., Karakashev, D. B., & Zhang, Y. (2017) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2017.06.020 · Cited by 27 · see citing works
Wang, C., Wang, Y., Chen, Z., Wei, W., Chen, X., Mannina, G., & Ni, B. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.160826 · Cited by 26 · see citing works
Cheng, H., Syu, J.-C., Tien, S.-Y., & Whang, L. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.04.069 · Cited by 25 · see citing works
Syngas Fermentation Into Biofuels and Biochemicals
Yasin, M., Cha, M., Chang, I. S., Atiyeh, H. K., Munasinghe, P., & Khanal, S. K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816856-1.00013-0 · Cited by 24 · see citing works
Wong, H. S. J., Bhubalan, K., & Abdullah, A. A. (2022) · Polymers · doi:10.3390/polym14040670 · Cited by 20 · see citing works
Acetate-assisted carbon monoxide fermentation of Clostridium sp. AWRP
Kwon, S. J., Lee, J., & Lee, H. S. (2021) · Process Biochemistry · doi:10.1016/j.procbio.2021.12.015 · Cited by 17 · see citing works
Scully, S. M., & Örlygsson, J. (2020) · Microorganisms · doi:10.3390/microorganisms8060945 · Cited by 16 · see citing works
COxFixation to Elementary Building Blocks: Anaerobic Syngas Fermentation vs. Chemical Catalysis
Perret, L., Campos, B. L. D. O., Delgado, K. H., Zevaco, T. A., Neumann, A., & Sauer, J. (2022) · Chemie Ingenieur Technik · doi:10.1002/cite.202200153 · Cited by 15 · see citing works
Engineering acetogens for biofuel production: From cellular biology to process improvement
Yang, C., Dong, L., Gao, Y., Jia, P., & Diao, Q. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111563 · Cited by 14 · see citing works
Scully, S. M., Brown, A. E., Ross, A. B., & Örlygsson, J. (2019) · Anaerobe · doi:10.1016/j.anaerobe.2019.03.004 · Cited by 14 · see citing works
Scully, S. M., & Örlygsson, J. (2019) · Amino Acids · doi:10.1007/s00726-019-02744-z · Cited by 14 · see citing works
Brodowski, F., Gutowska, N., Duber, A., Zagrodnik, R., Lezyk, M. J., & Oleśkowicz-Popiel, P. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.165367 · Cited by 13 · see citing works
Overcoming barriers to medium-chain fatty alcohol production
Su, Y., Mangus, A., Cordell, W. T., & Pfleger, B. F. (2024) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2023.103063 · Cited by 13 · see citing works
Rubinstein, G. M., Lipscomb, G. L., Williams-Rhaesa, A. M., Schut, G. J., Kelly, R. M., & Adams, M. W. W. (2020) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-020-02299-z · Cited by 11 · see citing works
Syngas Fermentation for Bioenergy Production: Advances in Bioreactor Systems
Sinharoy, A., Pakshirajan, K., & Lens, P. N. L. (2022) · Applied environmental science and engineering for a sustainable future · doi:10.1007/978-3-030-87633-3_13 · Cited by 11 · see citing works
Shi, X., Ju, F., Wei, W., Wu, L., Chen, X., & Ni, B. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155742 · Cited by 8 · see citing works
Scully, S. M., Brown, A. E., Mueller-Hilger, Y., Ross, A. B., & Örlygsson, J. (2021) · Microorganisms · doi:10.3390/microorganisms9010162 · Cited by 7 · see citing works
Microbial Production of Value-Added Chemicals from Pyrolysis Oil and Syngas
Neumann, A., Dörsam, S., Oswald, F., & Ochsenreither, K. (2015) · Springer eBooks · doi:10.1007/978-94-017-7475-8_4 · Cited by 6 · see citing works
Schwarz, I., Angelina, A., Hambrock, P., & Weuster‐Botz, D. (2024) · Molecules · doi:10.3390/molecules29112661 · Cited by 5 · see citing works
(S)-2-Hydroxyisovalerate Production from d-Xylose with CO-Converting Clostridium ragsdalei
Schwarz, I., Rupp, M., Frank, O., Daschner, A., & Weuster‐Botz, D. (2024) · Fermentation · doi:10.3390/fermentation10110546 · Cited by 3 · see citing works
Suazo, A., Olm, I. P., Otálora, F., Martínez-Ruano, J. A., Conejeros, R., Aroca, G. E., & Sousa, D. Z. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.172982 · Cited by 3 · see citing works
Effect of Endogenous and Exogenous Butyric Acid on Butanol Production From CO by Enriched Clostridia
He, Y., Lens, P. N. L., Veiga, M. C., & Kennes, C. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.828316 · Cited by 2 · see citing works
Solvent production by the hyperthermophilic archaeon Hyperthermus butylicus
Kim, S. D. (2021) · UWSpace (University of Waterloo)
Subashri, D., Sundaragnanam, K., Rahuman, A. A. A., & Mahalingam, P. U. (2025) · Systems Microbiology and Biomanufacturing · doi:10.1007/s43393-025-00380-1
Thunuguntla, R., Tanner, R. S., & Atiyeh, H. K. (2026) · Bioresource Technology · doi:10.1016/j.biortech.2026.134887
Lin, M., Elbek, E., Bailey, E. C., Lin, S.-H., Hamelers, H. V. M., ter Heijne, A., & Kuntke, P. (2026) · Separation and Purification Technology · doi:10.1016/j.seppur.2026.139030
- Authors
- Isom, C. E., Nanny, M. A., & Tanner, R. S.
- Affiliations
- University of Oklahoma (US)
- Corresponding author
- Isom, Catherine E.
- Venue
- Journal of Industrial Microbiology & Biotechnology
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-11-20
- Volume
- 42
- Issue
- 1
- Pages
- 29-38
- ISSN
- 1367-5435 (ISSN-L)
- 1476-5535
- OpenAlex
- W2120783226
- Cited by
- 52
- References
- 38
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 6 · 2023: 2 · 2022: 6 · 2021: 5 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 6 · 2016: 6 · 2015: 2
- FWCI
- 1.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Industrial Microbiology & Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Agriculture
- Cooperative State Research, Education, and Extension Service
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Physical Sciences › Engineering › Building and Construction › Anaerobic Digestion and Biogas Production
- Keywords
- primary alcohols, 1-pentanol, 1-hexanol, 1-propanol, n-butanol, propionic acid, butyrate, valeric acid, hexanoic acid, ferredoxin, carbon monoxide, conversion efficiency
- MeSH terms
- Acetone, Alcohol Dehydrogenase, Ethanol, Pentanols, Aldehyde Oxidoreductases, Amino Acid Sequence, Caproates, Clostridium, Fatty Acids, Fermentation, Gases, Molecular Sequence Data, Multienzyme Complexes, Magnetic Resonance Spectroscopy, Pentanoic Acids, Propionates, Acetic Acid, 2-Propanol, 1-Butanol, Butyric Acid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
