Genetic Linkage and Association Analysis for Loneliness in Dutch Twin and Sibling Pairs Points to a Region on Chromosome 12q23–24

The need to belong: Desire for interpersonal attachments as a fundamental human motivation.

Baumeister, R. F., & Leary, M. R. (1995) · Psychological Bulletin · doi:10.1037//0033-2909.117.3.497 · Cited by 23,245 · see citing works

Introduction to Quantitative Genetics.

Edwards, A. W. F., & Falconer, D. S. (1982) · Biometrics · doi:10.2307/2529912 · Cited by 21,447 · see citing works

Handbook of Social Psychology

DeLamater, J., & Ward, A. (2013) · Handbooks of sociology and social research · doi:10.1007/978-94-007-6772-0 · Cited by 7,565 · see citing works

Genetics and Analysis of Quantitative Traits

(2002) · Journal of Animal Breeding and Genetics · doi:10.1046/j.1439-0388.2002.00356.x · Cited by 6,172 · see citing works

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

Lander, E. S., & Kruglyak, L. (1995) · Nature Genetics · doi:10.1038/ng1195-241 · Cited by 5,196 · see citing works

The Revised UCLA Loneliness Scale: concurrent and discriminant validity evidence

Russell, D., Peplau, L. A., & Cutrona, C. E. (1980) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.39.3.472 · Cited by 5,173 · see citing works

Empirical threshold values for quantitative trait mapping.

Churchill, G. A., & Doerge, R. W. (1994) · Genetics · doi:10.1093/genetics/138.3.963 · Cited by 4,950 · see citing works

Merlin—rapid analysis of dense genetic maps using sparse gene flow trees

Abecasis, G. R., Cherny, S. S., Cookson, W., & Cardon, L. R. (2001) · Nature Genetics · doi:10.1038/ng786 · Cited by 3,323 · see citing works

Measures of Personality and Social Psychological Attitudes

(1991) · Elsevier eBooks · doi:10.1016/c2013-0-07551-2 · Cited by 3,237 · see citing works

Introduction to quantitative genetics

Falconer, D. S. (1960) · Helmholtz Centre for Ocean Research Kiel (GEOMAR) · Cited by 3,205 · see citing works

Loneliness: the experience of emotional and social isolation

Weiss, R. S. (1974) · Cited by 2,513 · see citing works

Loneliness as a specific risk factor for depressive symptoms: Cross-sectional and longitudinal analyses.

Cacioppo, J. T., Hughes, M. E., Waite, L. J., Hawkley, L. C., & Thisted, R. A. (2006) · Psychology and Aging · doi:10.1037/0882-7974.21.1.140 · Cited by 2,380 · see citing works

Loneliness: A Source Book of Current Theory, Research and Therapy

Blazer, D. G. (1983) · Journal of Gerontology · doi:10.1093/geronj/38.4.492 · Cited by 2,139 · see citing works

Loneliness: A Sourcebook of Current Theory, Research and Therapy.

Peplau, L. A., & Perlman, D. (1984) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2068915 · Cited by 1,937 · see citing works

Introduction to Quantitative Genetics.

Edwards, J. H., & Falconer, D. S. (1960) · Journal of the Royal Statistical Society Series A (General) · doi:10.2307/2342481 · Cited by 1,812 · see citing works

A high-resolution recombination map of the human genome

Kong, A., Gudbjartsson, D. F., Sainz, J., Jonsdottir, G. M., Gudjonsson, S. A., Richardsson, B., Sigurdardottir, S. L., Barnard, J., Hallbeck, B., Másson, G., et al. (2002) · Nature Genetics · doi:10.1038/ng917 · Cited by 1,750 · see citing works

Loneliness and health: potential mechanisms

Cacioppo, J. T., Hawkley, L. C., Crawford, L. E., Ernst, J. M., Burleson, M. H., Kowalewski, R. B., Malarkey, W. B., Van Cauter, E., & Berntson, G. G. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200205000-00005 · Cited by 1,149 · see citing works

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

Lewis, C. M., Levinson, D. F., Wise, L. H., DeLisi, L. E., Straub, R. E., Hovatta, I., Williams, N. M., Schwab, S. G., Pulver, A. E., Faraone, S. V., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/376549 · Cited by 1,134 · see citing works

Reducing Suicide--A National Imperative

(2002) · PsycEXTRA Dataset · doi:10.1037/e719942007-001 · Cited by 947 · see citing works

Handbook of Personal Relationships: Theory, Research and Interventions

Bryant, C. M., & Duck, S. W. (1998) · Journal of Marriage and the Family · doi:10.2307/353456 · Cited by 821 · see citing works

Handbook of personal relationships: theory, research, and interventions

(1989) · Choice Reviews Online · doi:10.5860/choice.26-4772 · Cited by 749 · see citing works

Attraction and close relationships.

Berscheid, E., & Reis, H. T. (1998) · Cited by 743 · see citing works

Handbook of communication and emotion: research, theory, applications, and contexts

(1998) · Choice Reviews Online · doi:10.5860/choice.35-5367 · Cited by 707 · see citing works

The genetics of schizophrenia and bipolar disorder: dissecting psychosis

Craddock, N., O’Donovan, M. C., & Owen, M. J. (2005) · Journal of Medical Genetics · doi:10.1136/jmg.2005.030718 · Cited by 574 · see citing works

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part III: Bipolar Disorder

Segurado, R., Detera‐Wadleigh, S. D., Levinson, D. F., Lewis, C. M., Gill, M., Nürnberger, J. I., Craddock, N. J., DePaulo, J. R., Baron, M., Gershon, E. S., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/376547 · Cited by 569 · see citing works

Lonely hearts: Psychological perspectives on loneliness

Ernst, J. M., & Cacioppo, J. T. (1999) · Applied and Preventive Psychology · doi:10.1016/s0962-1849(99)80008-0 · Cited by 566 · see citing works

Statistics in human genetics

Sham, P. C. (1997) · The HKU Scholars Hub (University of Hong Kong) · Cited by 555 · see citing works

Location of a Major Susceptibility Locus for Familial Schizophrenia on Chromosome 1q21-q22

Brzustowicz, L. M., Hodgkinson, K. A., Chow, E. W. C., Honer, W. G., & Bassett, A. S. (2000) · Science · doi:10.1126/science.288.5466.678 · Cited by 516 · see citing works

Do Lonely Days Invade the Nights? Potential Social Modulation of Sleep Efficiency

Cacioppo, J. T., Hawkley, L. C., Berntson, G. G., Ernst, J. M., Gibbs, A. C., Stickgold, R., & Hobson, J. A. (2002) · Psychological Science · doi:10.1111/1467-9280.00469 · Cited by 445 · see citing works

GRR: graphical representation of relationship errors

Abecasis, G. R., Cherny, S. S., Cookson, W., & Cardon, L. R. (2001) · Bioinformatics · doi:10.1093/bioinformatics/17.8.742 · Cited by 383 · see citing works

How Can I Connect With Thee?

Hawkley, L. C., Browne, M. W., & Cacioppo, J. T. (2005) · Psychological Science · doi:10.1111/j.1467-9280.2005.01617.x · Cited by 354 · see citing works

Depressive symptoms in late life: a 10-year follow-up

Heikkinen, R.-L., & Kauppinen, M. (2004) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2003.10.004 · Cited by 319 · see citing works

Loneliness and alcohol abuse: A review of evidences of an interplay

Åkerlind, I., & Hörnquist, J. O. (1992) · Social Science & Medicine · doi:10.1016/0277-9536(92)90300-f · Cited by 309 · see citing works

Pedigree tests of transmission disequilibrium

Abecasis, G. R., Cookson, W., & Cardon, L. R. (2000) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5200494 · Cited by 294 · see citing works

Netherlands Twin Register: A Focus on Longitudinal Research

Boomsma, D. I., Vink, J. M., Beijsterveldt, T. C. E. M. V., de Geus, E. J. C., Beem, A. L., Mulder, E. J. C. M., Derks, E. M., Riese, H., Willemsen, G. A. H. M., Bartels, M., et al. (2002) · Twin Research · doi:10.1375/136905202320906174 · Cited by 287 · see citing works

Measures of Depression and Loneliness

Shaver, P. R., & Brennan, K. A. (1991) · Elsevier eBooks · doi:10.1016/b978-0-12-590241-0.50010-1 · Cited by 263 · see citing works

Do Lonely Days Invade the Nights? Potential Social Modulation of Sleep Efficiency

Cacioppo, J. T., Hawkley, L. C., Berntson, G. G., et al. (2002) · Psychological Science · doi:10.1111/j.0956-7976.2002.00469.x · Cited by 214 · see citing works

Predisposition Locus for Major Depression at Chromosome 12q22-12q23.2

Abkevich, V., Camp, N. J., Hensel, C. H., Neff, C. D., Russell, D. L., Hughes, D. C., Plenk, A. M., Lowry, M. R., Richards, R. L., Carter, C., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/379978 · Cited by 194 · see citing works

Genome‐wide linkage survey for genetic loci that influence the development of depressive disorders in families with recurrent, early‐onset, major depression

Zubenko, G. S., Maher, B. S., Hughes, H. B., Zubenko, W. N., Stiffler, J. S., Kaplan, B. B., & Marazita, M. L. (2003) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20073 · Cited by 191 · see citing works

Genetic and Environmental Contributions to Loneliness in Adults: The Netherlands Twin Register Study

Boomsma, D. I., Willemsen, G., Dolan, C. V., Hawkley, L. C., & Cacioppo, J. T. (2005) · Behavior Genetics · doi:10.1007/s10519-005-6040-8 · Cited by 191 · see citing works

Linkage Analysis of Extremely Discordant and Concordant Sibling Pairs Identifies Quantitative-Trait Loci That Influence Variation in the Human Personality Trait Neuroticism

Fullerton, J. M., Cubin, M., Tiwari, H. K., Wang, C., Bomhra, A., Davidson, S. I., Miller, S., Fairburn, C. G., Goodwin, G. M., Neale, M. C., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/374178 · Cited by 179 · see citing works

Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families

Maziade, M., Roy, M.-A., Chagnon, Y. C., Cliche, D., Fournier, J.-P., Montgrain, N., Dion, C., Lavallée, J.-C., Garneau, Y., Gingras, N., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001594 · Cited by 157 · see citing works

Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q

Curtis, D., Kalsi, G., Brynjolfsson, J., McInnis, M. G., O’Neill, J., Smyth, C., Moloney, E., Murphy, P. L., McQuillin, A., Pétursson, H., et al. (2003) · Psychiatric Genetics · doi:10.1097/01.ypg.0000056684.89558.d2 · Cited by 152 · see citing works

A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22–21, 4p16, 6q14–22, 10q26 and 16p13.3

Ewald, H., Flint, T. J., Kruse, T. A., & Mors, O. N. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001074 · Cited by 124 · see citing works

Netherlands twin family study of anxious depression (NETSAD)

Boomsma, D. I., Beem, A. L., van den Berg, M., Dolan, C. V., Koopmans, J., Vink, J. M., de Geus, E. J. C., & Slagboom, P. E. (2000) · Twin Research · doi:10.1375/136905200320565300 · Cited by 121 · see citing works

Removing the Sampling Restrictions from Family-Based Tests of Association for a Quantitative-Trait Locus

Monks, S. A., & Kaplan, N. L. (2000) · The American Journal of Human Genetics · doi:10.1086/302745 · Cited by 116 · see citing works

Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships

Nash, M. W. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh239 · Cited by 112 · see citing works

Genetics and genomics of depression

Hamet, P., & Tremblay, J. (2005) · Metabolism · doi:10.1016/j.metabol.2005.01.006 · Cited by 110 · see citing works

Genomewide Significant Linkage to Migrainous Headache on Chromosome 5q21

Nyholt, D. R., Morley, K. I., Ferreira, M. A. R., Medland, S. E., Boomsma, D. I., Heath, A. C., Merikangas, K. R., Montgomery, G. W., & Martin, N. G. (2005) · The American Journal of Human Genetics · doi:10.1086/444510 · Cited by 107 · see citing works

Genome‐wide linkage analyses of extended Utah pedigrees identifies loci that influence recurrent, early‐onset major depression and anxiety disorders

Camp, N. J., Lowry, M. R., Richards, R. L., Plenk, A. M., Carter, C., Hensel, C. H., Abkevich, V., Skolnick, M. H., Shattuck, D., Rowe, K. G., et al. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30177 · Cited by 106 · see citing works

Loneliness and the Evaluation of Relational Events

Duck, S. W., Pond, K., & Leatham, G. (1994) · Journal of Social and Personal Relationships · doi:10.1177/0265407594112006 · Cited by 105 · see citing works

Improved set of short-tandem-repeat polymorphisms for screening the human genome.

Yuan, B., Vaske, D. A., Weber, J. L., Beck, J. S., & Sheffield, V. C. (1997) · PubMed · Cited by 99 · see citing works

Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families

Myles‐Worsley, M., Coon, H. H., McDowell, J. E., Brenner, C. A., Hoff, M., Lind, B., Bennett, P., Freedman, R., Clementz, B. A., & Byerley, W. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19991015)88:5 · Cited by 98 · see citing works

Genome scan for susceptibility loci for schizophrenia and bipolar disorder

Bailer, U. F., Leisch, F., Meszaros, K., Lenzinger, E., Willinger, U., Strobl, R., Heiden, A. M., Gebhardt, C., Döge, E., Fuchs, K., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01320-3 · Cited by 96 · see citing works

Reducing Suicide: A National Imperative

Maltsberger, J. T. (2003) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000087330.14485.41 · Cited by 96 · see citing works

Genetic and Environmental Contributions to Loneliness in Children

McGuire, S., & Clifford, J. (2000) · Psychological Science · doi:10.1111/1467-9280.00293 · Cited by 94 · see citing works

Interpersonal communication problems associated with depression and loneliness

Segrin, C. G. (1996) · Elsevier eBooks · doi:10.1016/b978-012057770-5/50010-2 · Cited by 85 · see citing works

Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder

Ekholm, J. M., Kieseppä, T., Hiekkalinna, T., Partonen, T., Paunio, T., Perola, M., Ekelund, J., Lönnqvist, J. K., Ijäs, P. H., & Peltonen, L. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg199 · Cited by 80 · see citing works

A genome-wide scan points to a susceptibility locus for bipolar disorder on chromosome 12

Shink, E., Morissette, J., Sherrington, R., & Barden, N. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001601 · Cited by 79 · see citing works

Seasonal Suicide Attempts and Forms of Loneliness

Wenz, F. V. (1977) · Psychological Reports · doi:10.2466/pr0.1977.40.3.807 · Cited by 76 · see citing works

Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease

Jones, I. R., Jacobsen, N., Green, E., Elvidge, G. P., Owen, M. J., & Craddock, N. J. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4000989 · Cited by 71 · see citing works

Perspective on loneliness

Peplau, L. (1982) · Medical Entomology and Zoology · Cited by 59 · see citing works

Localization of Bipolar Susceptibility Locus by Molecular Genetic Analysis of the Chromosome 12q23-q24 Region in Two Pedigrees With Bipolar Disorder and Darier’s Disease

Green, E., Elvidge, G. P., Jacobsen, N., Pourcain, B. S., Jones, I. R., O’Donovan, M. C., Kirov, G., Owen, M. J., & Craddock, N. J. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.1.35 · Cited by 58 · see citing works

Further evidence for a bipolar risk gene on chromosome 12q24 suggested by investigation of haplotype sharing and allelic association in patients from the Faroe Islands

Degn, B., Lundorf, M. D., Wang, A., Vang, M., Mors, O. N., Kruse, T. A., & Ewald, H. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000882 · Cited by 52 · see citing works

Chromosome workshop: Chromosomes 11, 14, and 15

Craddock, N. J., Lendon, C. L., Cichon, S., Culverhouse, R., Detera‐Wadleigh, S. D., Devon, R. S., Faraone, S. V., Foroud, T., Gejman, P. V., Leonard, S. S., et al. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19990618)88:3 · Cited by 51 · see citing works

Meta-analysis of four new genome scans for lipid parameters and analysis of positional candidates in positive linkage regions

Heijmans, B. T., Beekman, M., Putter, H., Lakenberg, N., van der Wijk, H. J., Whitfield, J. B., Danielle Posthuma, B., Pedersen, N. L., Martin, N. G., Boomsma, D. I., et al. (2005) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201466 · Cited by 50 · see citing works

Genome scan of three quantitative traits in schizophrenia pedigrees

Wilcox, M., Faraone, S. V., Lasky-Su, J. A., Eerdewegh, P. V., & Tsuang, M. T. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01465-8 · Cited by 46 · see citing works

Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region

Shink, É., Harvey, M., Tremblay, M., Gagné, B., Belleau, P., Raymond, C., Labbé, M., Dubé, M., Lafrenière, R. G., & Barden, N. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30165 · Cited by 35 · see citing works

Association study on the DUSP6 gene, an affective disorder candidate gene on 12q23, performed by using fluorescence resonance energy transfer-based melting curve analysis on the LightCycler

Toyota, T., Watanabe, A., Shibuya, H., Nankai, M., Hattori, E., Yamada, K., Kurumaji, A., Karkera, J. D., Detera‐Wadleigh, S. D., & Yoshikawa, T. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000748 · Cited by 34 · see citing works

Evidence for a QTL on chromosome 19 influencing LDL cholesterol levels in the general population

Beekman, M., Heijmans, B. T., Martin, N. G., Whitfield, J. B., Pedersen, N. L., DeFaire, U., Snieder, H., Lakenberg, N., Suchiman, H. E. D., de Knijff, P., et al. (2003) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201053 · Cited by 31 · see citing works

Linkage disequilibrium mapping of bipolar affective disorder at 12q23‐q24 provides evidence for association at CUX2 and FLJ32356

Pourcain, B. S., Kirov, G., Green, E., Craddock, N. J., & Owen, M. J. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30081 · Cited by 28 · see citing works

Identification of a potential Bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4

Glaser, B., Kirov, G., Bray, N. J., Green, E., O’Donovan, M. C., Craddock, N. J., & Owen, M. J. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001689 · Cited by 26 · see citing works

Mapping Multiple Quantitative Trait Loci for Ordinal Traits

Yi, N., Xu, S., George, V. T., & Allison, D. B. (2003) · Behavior Genetics · doi:10.1023/b:bege.0000009473.43185.43 · Cited by 22 · see citing works

Contact difficulties and experience of loneliness in depressed patients and non‐psychiatric controls

Eisemann, M. R. (1984) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1984.tb01193.x · Cited by 20 · see citing works

Mutational analysis of two positional candidate susceptibility genes for bipolar disorder on chromosome 12q23-q24

Green, E., Elvidge, G. P., Owen, M. J., & Craddock, N. J. (2003) · Psychiatric Genetics · doi:10.1097/01.ypg.0000057882.80011.9e · Cited by 12 · see citing works

Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser

Stenger, J. E., Xu, H., Haynes, C. S., Hauser, E. R., Pericak‐Vance, M. A., Goldschmidt‐Clermont, P. J., & Vance, J. M. (2005) · BMC Bioinformatics · doi:10.1186/1471-2105-6-95 · Cited by 11 · see citing works

Depressed patients and non‐psychiatric controls: discriminant analysis on social environment variables

Eisemann, M. R. (1985) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1985.tb05062.x · Cited by 8 · see citing works

Untitled work

(1999) · doi:10.1002/(sici)1096-8644(199903)108:3

Alone in the crowd: The structure and spread of loneliness in a large social network.

Cacioppo, J. T., Fowler, J. H., & Christakis, N. A. (2009) · Journal of Personality and Social Psychology · doi:10.1037/a0016076 · Cited by 844 · see citing works

Social isolation

Cacioppo, J. T., Hawkley, L. C., Norman, G. J., & Berntson, G. G. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06028.x · Cited by 554 · see citing works

Loneliness in the Modern Age: An Evolutionary Theory of Loneliness (ETL)

Cacioppo, J. T., & Cacioppo, S. (2018) · Advances in Experimental Social Psychology · doi:10.1016/bs.aesp.2018.03.003 · Cited by 481 · see citing works

Understanding loneliness in the twenty-first century: an update on correlates, risk factors, and potential solutions

Lim, M. H., Eres, R., & Vasan, S. (2020) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-020-01889-7 · Cited by 438 · see citing works

Netherlands Twin Register: From Twins to Twin Families

Boomsma, D. I., de Geus, E. J. C., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J., Danielle Posthuma, B., van Beijsterveldt, T. C. E. M., Hudziak, J. J., Bartels, M., et al. (2006) · Twin Research and Human Genetics · doi:10.1375/183242706779462426 · Cited by 401 · see citing works

Genome-Wide Linkage Scan for Athlete Status in 700 British Female DZ Twin Pairs

de Moor, M. H. M., Spector, T. D., Cherkas, L. F., Falchi, M., Hottenga, J., Boomsma, D. I., & de Geus, E. J. C. (2007) · Twin Research and Human Genetics · doi:10.1375/twin.10.6.812 · Cited by 247 · see citing works

Loneliness in psychosis: a systematic review

Lim, M. H., Gleeson, J., Álvarez‐Jiménez, M., & Penn, D. L. (2018) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-018-1482-5 · Cited by 235 · see citing works

Social Neuroscience: Progress and Implications for Mental Health

Cacioppo, J. T., Amaral, D. G., Blanchard, J. J., Cameron, J. L., Carter, C. S., Crews, D. P., Fiske, S. T., Heatherton, T. F., Johnson, M. K., Kozak, M. J., et al. (2007) · Perspectives on Psychological Science · doi:10.1111/j.1745-6916.2007.00032.x · Cited by 132 · see citing works

Loneliness in Elderly People, Associated Factors and Its Correlation with Quality of Life: A Field Study from Western Turkey.

Arslantaş, H., Adana, F., Ergın, F., Kayar, D., & Acar, G. (2015) · PubMed Central · Cited by 121 · see citing works

The Genetics of Loneliness: Linking Evolutionary Theory to Genome-Wide Genetics, Epigenetics, and Social Science

Goossens, L., van Roekel, E., Verhagen, M., Cacioppo, J. T., Cacioppo, S., Maes, M., & Boomsma, D. I. (2015) · Perspectives on Psychological Science · doi:10.1177/1745691614564878 · Cited by 103 · see citing works

Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation

Gao, J., Davis, L. K., Hart, A. B., Sanchez‐Roige, S., Han, L., Cacioppo, J. T., & Palmer, A. A. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.197 · Cited by 102 · see citing works

Familial Resemblance for Loneliness

Distel, M. A., Rebollo‐Mesa, I., Abdellaoui, A., Derom, C. A., Willemsen, G. A. H. M., Cacioppo, J. T., & Boomsma, D. I. (2010) · Behavior Genetics · doi:10.1007/s10519-010-9341-5 · Cited by 94 · see citing works

Depressive Symptoms Predict Mucosal Wound Healing

Bosch, J. A., Engeland, C. G., Cacioppo, J. T., & Marucha, P. T. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318148c682 · Cited by 91 · see citing works

Genetic Contributions to Loneliness and Their Relevance to the Evolutionary Theory of Loneliness

Spithoven, A., Cacioppo, S., Goossens, L., & Cacioppo, J. (2019) · Perspectives on Psychological Science · doi:10.1177/1745691618812684 · Cited by 77 · see citing works

Longitudinal Stability of the CBCL-Juvenile Bipolar Disorder Phenotype: A Study in Dutch Twins

Boomsma, D. I., Rebollo, I., Derks, E. M., van Beijsterveldt, T. C. E. M., Althoff, R. R., Rettew, D. C., & Hudziak, J. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.028 · Cited by 80 · see citing works

Longitudinal Genetic Analysis for Loneliness in Dutch Twins

Boomsma, D. I., Cacioppo, J. T., Muthén, B., Asparouhov, T., & Clark, S. (2007) · Twin Research and Human Genetics · doi:10.1375/twin.10.2.267 · Cited by 57 · see citing works

Predicting loneliness with polygenic scores of social, psychological and psychiatric traits

Abdellaoui, A., Nivard, M. G., Hottenga, J., Fedko, I. O., Verweij, K. J. H., Baselmans, B. M. L., Ehli, E. A., Davies, G. E., Bartels, M., Boomsma, D. I., et al. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12472 · Cited by 53 · see citing works

Chromosome 9: linkage for borderline personality disorder features

Distel, M. A., Hottenga, J., Trull, T. J., & Boomsma, D. I. (2008) · Psychiatric Genetics · doi:10.1097/ypg.0b013e3283118468 · Cited by 32 · see citing works

Causes of loneliness

Rokach, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815618-6.00006-0 · Cited by 29 · see citing works

Neurogenetics and Epigenetics of Loneliness

Bowirrat, A., Elman, I., Dennen, C. A., Gondré-Lewis, M. C., Cadet, J. L., Khalsa, J., Baron, D., Soni, D., Gold, M. S., McLaughlin, T., et al. (2023) · Psychology Research and Behavior Management · doi:10.2147/prbm.s423802 · Cited by 23 · see citing works

Genetic and environmental causes of variation in perceived loneliness in young people

Waaktaar, T., & Torgersen, S. O. (2012) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32064 · Cited by 23 · see citing works

Influence of Social Environment on Loneliness in Older Adults: Moderation by Polymorphism in the CRHR1

Chou, K., Cacioppo, J. T., Meena Kumari, B., & Song, Y. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.11.002 · Cited by 22 · see citing works

The Genetics of Political Attitudes and Behavior: Claims and Refutations

Joseph, J. (2010) · Ethical Human Psychology and Psychiatry · doi:10.1891/1559-4343.12.3.200 · Cited by 22 · see citing works

ADHD and Genetics: A Consensus Reconsidered

Joseph, J. (2009) · doi:10.1007/978-1-137-02058-1_3 · Cited by 20 · see citing works

Genetic Causation

Krimsky, S. (2013) · Advances in child development and behavior · doi:10.1016/b978-0-12-397947-6.00011-8 · Cited by 18 · see citing works

The roles of depression and social relationships in the onset and course of loneliness amongst Nigerian elders

Ojagbemi, A., Bello, T., & Gureje, O. (2020) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5451 · Cited by 16 · see citing works

Comparing phenotypic, genetic, and environmental associations between personality and loneliness

Freilich, C. D., Mann, F. D., South, S. C., & Krueger, R. F. (2022) · Journal of Research in Personality · doi:10.1016/j.jrp.2022.104314 · Cited by 13 · see citing works

A SNP , Gene, and Polygenic Risk Score Approach of Oxytocin‐Vasopressin Genes in Adolescents’ Loneliness

Verhagen, M., Verweij, K. J. H., Lodder, G. M. A., Goossens, L., Verschueren, K., Leeuwen, K. G. V., Noortgate, W. V. D., Claes, S. J., Bijttebier, P., Assche, E. V., et al. (2019) · Journal of Research on Adolescence · doi:10.1111/jora.12480 · Cited by 11 · see citing works

Connecting loneliness with pathological personality traits: Evidence for genetic and environmental mediation from a study of older twins.

Freilich, C. D., McGue, M. K., South, S. C., Roisman, G. I., & Krueger, R. F. (2023) · Personality Disorders Theory Research and Treatment · doi:10.1037/per0000635 · Cited by 10 · see citing works

Perceived Social Isolation within Personal and Evolutionary Timescales

Hawkley, L. C., Cacioppo, J. T., & Correll, J. (2013) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780195398700.013.0017 · Cited by 9 · see citing works

Einsamkeit – erblich, ansteckend, tödlich

Spitzer, M. (2016) · Nervenheilkunde · doi:10.1055/s-0037-1616442 · Cited by 8 · see citing works

Candidate region linkage analysis in twins discordant or concordant for depression symptomatology

Christiansen, L., Tan, Q., Kruse, T. A., McGue, M. K., & Christensen, K. (2008) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30841 · Cited by 6 · see citing works

Genetic underpinnings of sociability in the UK BiobankPreprint

Bralten, J., Klemann, C. J. H. M., Mota, N. R., Witte, W. D., Arango, C., Fabbri, C., Kas, M. J., van der Wee, N. J. A., Penninx, B. W. J. H., Serretti, A., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/781195 · Cited by 6 · see citing works

Genetics, Social Behaviors, Social Environments and Aging

Harris, J. R. (2007) · Twin Research and Human Genetics · doi:10.1375/twin.10.2.235 · Cited by 4 · see citing works

Bereft and Left: The interplay between insecure attachment, isolation, and neurobiology

Bell, K., McMillin, K., & Ethridge, L. E. (2022) · Developmental Review · doi:10.1016/j.dr.2022.101020 · Cited by 3 · see citing works

Van generatie op generatie : Gelijkenis tussen ouders en kinderen

Dykstra, P. A., & Liefbroer, A. (2007) · Amsterdam University Press eBooks · doi:10.5117/9789053564691 · Cited by 2 · see citing works

Abilities, Difficulties, and Developmental Perspectives

Margalit, M. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6284-3_2

onely people choose money over relationships in pursuit of happiness

김가영, Suh, E. M., & Lim, N. (2016) · 한국심리학회지 사회및성격 · doi:10.21193/kjspp.2016.30.1.001

Behavior Genetic Analysis of Loneliness

Dargan, S., MacDonald, K. B., & Schermer, J. A. (2025) · Springer eBooks · doi:10.1007/978-3-032-02959-1_13

Genetic Linkage and Association Analysis for Loneliness in Dutch Twin and Sibling Pairs Points to a Region

On Chromosome, Q., Boomsma, D. I., Slagboom, P. E., & Danielle Posthuma, B. (2005)

Genetics of loneliness: a study from the Netherlands Twin Register.

Boomsma, D. I., Willemsen, G. A. H. M., de Geus, E. J. C., Hawkley, L. C., Cacioppo, J. T., & Danielle Posthuma, B. (2004) · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) · Cited by 1 · see citing works

Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation

Gao, J., Davis, L. K., Hart, A. B., Sanchez‐Roige, S., Han, L., Cacioppo, J. T., & Palmer, A. A. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.197 · Cited by 102 · see citing works

Genetic and Environmental Contributions to Loneliness in Adults: The Netherlands Twin Register Study

Boomsma, D. I., Willemsen, G., Dolan, C. V., Hawkley, L. C., & Cacioppo, J. T. (2005) · Behavior Genetics · doi:10.1007/s10519-005-6040-8 · Cited by 191 · see citing works

American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 147B:385–391 (2008) Genetic and Environmental Contributions to Stability in Loneliness Throughout Childhood

Bartels, M., Hudziak, J. J., & Boomsma, D. I. (2009)