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Cited by 117Sleep and Work-Related FatigueWorkplace Health and Well-beingCircadian rhythm and melatonin

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Shift-work and cardiovascular disease: a population-based 22-year follow-up study

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Hublin, Christer, Partinen, Markku, Koskenvuo, Karoliina, Silventoinen, Karri, Koskenvuo, Markku, Kaprio, Jaakko·2010·European Journal of Epidemiology
DOI 10.1007/s10654-010-9439-3
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Abstract

Studies on the association between shift-work and cardiovascular disease (CVD), in particular coronary heart disease (CHD), have given conflicting results. In this prospective population-based study we assessed the association of shift-work with three endpoints: CHD mortality, disability retirement due to CVD, and incident hypertension. A cohort of 20,142 adults (the Finnish Twin Cohort) was followed from 1982 to 2003. Type of working time (daytime/nighttime/shift-work) was assessed by questionnaires in 1975 (response rate 89%) and in 1981 (84%). Causes of death, information on disability retirement and hypertension medication were obtained from nationwide official registers. Cox proportional hazard models were used to obtain hazard ratios (HR) for each endpoint by type of working time. Adjustments were made for 14 socio-demographic and lifestyle covariates. 76.9% were daytime workers and 9.5% shift-workers both in 1975 and in 1981. During the follow-up, 857 deaths due to CHD, 721 disability retirements due to CVD, and 2,642 new cases of medicated hypertension were observed. However, HRs for shift-work were not significant (mortality HR men 1.09 and women 1.22; retirement 1.15 and 0.96; hypertension 1.15 and 0.98, respectively). The results were essentially similar after full adjustments for all covariates. Within twin pairs, no association between shift work and outcome was observed. Our results do not support an association between shift-work and cardiovascular morbidity.

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Metadata

Authors
Hublin, C., Partinen, M., Koskenvuo, K., Silventoinen, K., Koskenvuo, M., & Kaprio, J.
Affiliations
  • Finnish Institute of Occupational Health (FI)
  • University of Helsinki (FI)
Corresponding author
Hublin, Christer
ORCID
Venue
European Journal of Epidemiology
Publisher
Springer Science and Business Media LLC
Published
2010-03-14
Volume
25
Issue
5
Pages
315-323
ISSN
  • 0393-2990 (ISSN-L)
  • 1573-7284
DOI
10.1007/s10654-010-9439-3
OpenAlex
W2098774138
Cited by
117
References
38
Citations by year
2026: 2 · 2025: 4 · 2024: 3 · 2023: 3 · 2022: 8 · 2021: 9 · 2020: 5 · 2019: 7 · 2018: 4 · 2017: 8 · 2016: 7 · 2015: 11 · 2014: 11 · 2013: 10 · 2012: 11
FWCI
13.32
Type
journal article
Language
en
Open access
Licence
Locations
  • European Journal of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, other-oa)
  • Trinity's Access to Research Output (TARA) (Trinity College Dublin) (submittedVersion)
  • STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Keywords
shift work, cardiovascular disease, coronary heart disease mortality, disability retirement, hypertension, working hours, night work, twin cohort, occupational health
MeSH terms
Adult, Cardiovascular Diseases, Female, Finland, Follow-Up Studies, Humans, Male, Middle Aged, Surveys and Questionnaires, Work Schedule Tolerance, Proportional Hazards Models, Twin Studies as Topic, Young Adult

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