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Shift-work and cardiovascular disease: a population-based 22-year follow-up study
Open accessAbstract
Studies on the association between shift-work and cardiovascular disease (CVD), in particular coronary heart disease (CHD), have given conflicting results. In this prospective population-based study we assessed the association of shift-work with three endpoints: CHD mortality, disability retirement due to CVD, and incident hypertension. A cohort of 20,142 adults (the Finnish Twin Cohort) was followed from 1982 to 2003. Type of working time (daytime/nighttime/shift-work) was assessed by questionnaires in 1975 (response rate 89%) and in 1981 (84%). Causes of death, information on disability retirement and hypertension medication were obtained from nationwide official registers. Cox proportional hazard models were used to obtain hazard ratios (HR) for each endpoint by type of working time. Adjustments were made for 14 socio-demographic and lifestyle covariates. 76.9% were daytime workers and 9.5% shift-workers both in 1975 and in 1981. During the follow-up, 857 deaths due to CHD, 721 disability retirements due to CVD, and 2,642 new cases of medicated hypertension were observed. However, HRs for shift-work were not significant (mortality HR men 1.09 and women 1.22; retirement 1.15 and 0.96; hypertension 1.15 and 0.98, respectively). The results were essentially similar after full adjustments for all covariates. Within twin pairs, no association between shift work and outcome was observed. Our results do not support an association between shift-work and cardiovascular morbidity.
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“Follow-up rates for this cohort remain at approximately 90%, and the overall death follow-up is >98% complete.49”
From Total and Cause-Specific Mortality of U.S. Nurses Working Rotating Night Shifts (2015) · cites this paper as [49]
In the citing paper
“the National Death Index, which is highly sensitive and specific in this cohort.49”
From Total and Cause-Specific Mortality of U.S. Nurses Working Rotating Night Shifts (2015) · cites this paper as [49]
Citations
Cites
A Note on Robust Variance Estimation for Cluster‐Correlated Data
Williams, R. L. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00645.x · Cited by 2,501
Health disorders of shift workers
Knutsson, A. (2003) · Occupational Medicine · doi:10.1093/occmed/kqg048 · Cited by 1,218
Shift work, risk factors and cardiovascular disease
Bøggild, H., & Knutsson, A. (1999) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.410 · Cited by 683
Relationship of Leisure-Time Physical Activity and Mortality
Kujala, U. M., Kaprio, J. A., Sarna, S. J., & Koskenvuo, M. J. (1998) · JAMA · doi:10.1001/jama.279.6.440 · Cited by 620
Prospective study of shift work and risk of coronary heart disease in women
Kawachi, I., Colditz, G. A., Stampfer, M. J., Willett, W. C., Manson, J. E., Speizer, F. E., & Hennekens, C. H. (1995) · Circulation · doi:10.1161/01.cir.92.11.3178 · Cited by 524
Sleep and Mortality: A Population-Based 22-Year Follow-Up Study
Hublin, C., Partinen, M., Koskenvuo, M. J., & Kaprio, J. A. (2007) · SLEEP · doi:10.1093/sleep/30.10.1245 · Cited by 439
Life satisfaction and depression in a 15-year follow-up of healthy adults
Koivumaa-Honkanen, H. T., Kaprio, J. A., Honkanen, R., Viinam�ki, H., & Koskenvuo, M. J. (2004) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-004-0833-6 · Cited by 346
Ueshima, H. (2007) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.e529 · Cited by 280
Genetic Influences on Use and Abuse of Alcohol: A Study of 5638 Adult Finnish Twin Brothers
Kaprio, J. A., Koskenvuo, M. J., LANGINVAINIO, H., Romanov, K., Sarna, S. J., & Rose, R. J. (1987) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1987.tb01324.x · Cited by 270
Genetic and Environmental Factors in Complex Diseases: The Older Finnish Twin Cohort
Kaprio, J. A., & Koskenvuo, M. J. (2002) · Twin Research · doi:10.1375/twin.5.5.358 · Cited by 263
Frost, P., Kolstad, H. A., & Bonde, J. P. (2009) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.1319 · Cited by 245
Insufficient sleep—a population-based study in adults
Hublin, C., Kaprio, J., Partinen, M., & Koskenvuo, M. (2001) · Sleep · doi:10.1093/sleep/24.4.392 · Cited by 240
Genetic and Environmental Factors in Complex Diseases: The Older Finnish Twin Cohort
Kaprio, J. A., & Koskenvuo, M. (2002) · Twin Research · doi:10.1375/136905202320906093 · Cited by 233
Heritability of diurnal type: a nationwide study of 8753 adult twin pairs
Koskenvuo, M. J., Hublin, C., Partinen, M., Heikkila, K. V., & Kaprio, J. A. (2007) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2007.00580.x · Cited by 226
A Prospective Cohort Study of Shift Work and Risk of Ischemic Heart Disease in Japanese Male Workers
Fujino, Y., Iso, H., Tamakoshi, A., Inaba, Y., Koizumi, A., Kubo, T., & Yoshimura, T. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj185 · Cited by 225
Shiftwork and myocardial infarction: a case-control study.
Knutsson, A., Hallquist, J., Reuterwall, C., Theorell, T., & Åkerstedt, T. (1999) · Occupational and Environmental Medicine · doi:10.1136/oem.56.1.46 · Cited by 208
Kujala, U. M. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf151 · Cited by 207
Methodological Aspects of Shift-Work Research
Knutsson, A. (2004) · Chronobiology International · doi:10.1081/cbi-200038525 · Cited by 203
Binge Drinking in Midlife and Dementia Risk
rvenp, T. J., Rinne, J. O., Koskenvuo, M. J., ih, I. R., & Kaprio, J. A. (2005) · Epidemiology · doi:10.1097/01.ede.0000181307.30826.6c · Cited by 141
Sørensen, T. I. A., Rissanen, A., Korkeila, M., & Kaprio, J. A. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020171 · Cited by 133
Relationship between shift work and onset of hypertension in a cohort of manual workers
Morikawa, Y., Nakagawa, H., Miura, K., Ishizaki, M., Tabata, M., Nishijo, M., 東口, 和., Yoshita, K., Sagara, T., Kido, T., et al. (1999) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.411 · Cited by 122
Shift Work Is a Risk Factor for Increased Blood Pressure in Japanese Men
Suwazono, Y., Dochi, M., Sakata, K., Okubo, Y., Oishi, M., Tanaka, K., Kobayashi, E., & Nogawa, K. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.114553 · Cited by 121
A 12 year prospective study of circulatory disease among Danish shift workers
Tüchsen, F., Hannerz, H., & Burr, H. (2006) · Occupational and Environmental Medicine · doi:10.1136/oem.2006.026716 · Cited by 111
Oishi, M., Suwazono, Y., Sakata, K., Okubo, Y., Harada, H., Kobayashi, E., Uetani, M., & Nogawa, K. (2005) · Journal of Hypertension · doi:10.1097/01.hjh.0000189870.55914.b3 · Cited by 110
Virtanen, S. V., & Notkola, V. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.3.614 · Cited by 100
Smoking among Shift Workers: More Than a Confounding Factor
van Amelsvoort, L. G. P. M., Jansen, N., & Kant, I. (2006) · Chronobiology International · doi:10.1080/07420520601089539 · Cited by 98
Cardiovascular Mortality in Twins and the Fetal Origins Hypothesis
Christensen, K., Wienke, A., Skytthe, A., Holm, N. V., Vaupel, J. W., & Yashin, A. I. (2001) · Twin Research · doi:10.1375/1369052012506 · Cited by 96
The Relationship Between Shift Work and the Onset of Hypertension in Male Japanese Workers
Sakata, K., Suwazono, Y., Harada, H., Okubo, Y., Kobayashi, E., & Nogawa, K. (2003) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000085893.98441.96 · Cited by 91
Self-reported life satisfaction and recovery from depression in a 1-year prospective study
Koivumaa-Honkanen, H. T., Honkanen, R., Antikainen, R., Hintikka, J., Laukkanen, E., Honkalampi, K. M., & Viinamäki, H. T. (2001) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2001.00046.x · Cited by 79
de Geus, E. J. C., Posthuma, D., IJzerman, R. G., & Boomsma, D. I. (2001) · Twin Research · doi:10.1375/twin.4.5.385 · Cited by 60
Prevalent cardiovascular disease, risk factors and selection out of shift work
Mika Kivimaki, B., Virtanen, M., Elovainio, M. J., Väänänen, A., Keltikangas‐Järvinen, L., & Vahtera, J. (2006) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.1000 · Cited by 58
Cardiovascular Mortality in Twins and the Fetal Origins Hypothesis
Christensen, K., Wienke, A., Skytthe, A., et al. (2001) · Twin Research · doi:10.1375/twin.4.5.344 · Cited by 56
Self-reported alcohol use: a longitudinal study of 12,994 adults.
Romanov, K., Rose, R. J., Kaprio, J. A., Koskenvuo, M., LANGINVAINIO, H., & Sarna, S. (1987) · PubMed · Cited by 37
Threats and opportunities : findings of Finnish Quality of Work Life Surveys 1977-2003
Lehto, A.-M., & Sutela, H. (2005) · Doria (University of Helsinki) · Cited by 31
A 15-year prospective study of shift work and disability pension: Table 1
Tüchsen, F., Christensen, K. B., Lund, T., & Feveile, H. (2008) · Occupational and Environmental Medicine · doi:10.1136/oem.2007.036525 · Cited by 23
Shiftwork in the 21st century : challenges for research and practice
Hornberger, S., & Shiftwork (2000) · Cited by 18
Stability and change of volume and intensity of physical activity as predictors of hypertension
Hernelahti, M., Kujala, U. M., & Kaprio, J. A. (2004) · Scandinavian Journal of Public Health · doi:10.1080/14034940410024167 · Cited by 15
Shift work and ischaemic heart disease
Knutsson, A. (2008) · Occupational and Environmental Medicine · doi:10.1136/oem.2007.034165 · Cited by 12
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Jaddoe, V. W. V., van Duijn, C. M., van der Heijden, A. J., Mackenbach, J. P., Moll, H. A., Steegers, E. A. P., Tiemeier, H., Uitterlinden, A. G., Verhulst, F. C., & Hofman, A. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9516-7 · Cited by 1,027
“Socio-economic status is related to various perinatal and postnatal health outcomes and of major interest in the study [93–109].”
BackgroundShift work and vascular events: systematic review and meta-analysis
Vyas, M. V., Garg, A. X., Iansavichus, A. V., Costella, J., Donner, A., Laugsand, L. E., Janszky, I., Mrkobrada, M., Parraga, G., & Hackam, D. G. (2012) · BMJ · doi:10.1136/bmj.e4800 · Cited by 840
Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women
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“19 Here, when participants with hypertension, elevated cholesterol levels or diabetes were excluded at baseline and throughout follow-up, a significant dose-response relationship between rotating night shift work and CHD risk in NHS, but not NHS2, was observed.”
BackgroundTorquati, L., Mielke, G. I., Brown, W. J., & Kolbe-Alexander, T. (2018) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.3700 · Cited by 510
“Risk of bias assessment Study Risk of bias per item Overall risk of bias Major Domain Minor Domain a 1 2 3 4 5 1 2 3 4 5 Cohort studies Allesøe et al 2010 (36) 1 1 0 0 0 U U 0 0 0 High Biggi et al 2008 (40) 0 0 0 0 0 U U 0 U U Low Brown et al 2009 (17) 0 1 0 0 0 U U 0 0 0 Moderate Ervasti et al 2016 (27) 1 1 0 0 0 U U…”
BackgroundInfluential
Metadata
- Authors
- Hublin, C., Partinen, M., Koskenvuo, K., Silventoinen, K., Koskenvuo, M., & Kaprio, J.
- Affiliations
- Finnish Institute of Occupational Health (FI)
- University of Helsinki (FI)
- Corresponding author
- Hublin, Christer
- Venue
- European Journal of Epidemiology
- Published
- 2010-03-14
- Volume
- 25
- Issue
- 5
- Pages
- 315-323
- ISSN
- 0393-2990 (ISSN-L)
- 1573-7284
- OpenAlex
- W2098774138
- Cited by
- 117
- References
- 38
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 3 · 2023: 3 · 2022: 8 · 2021: 9 · 2020: 5 · 2019: 7 · 2018: 4 · 2017: 8 · 2016: 7 · 2015: 11 · 2014: 11 · 2013: 10 · 2012: 11
- FWCI
- 13.32
- Type
- journal article
- Language
- en
- Open access
- green
- hal.science
- Licence
- other-oa
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- Trinity's Access to Research Output (TARA) (Trinity College Dublin) (submittedVersion)
- STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Keywords
- shift work, cardiovascular disease, coronary heart disease mortality, disability retirement, hypertension, working hours, night work, twin cohort, occupational health
- MeSH terms
- Adult, Cardiovascular Diseases, Female, Finland, Follow-Up Studies, Humans, Male, Middle Aged, Surveys and Questionnaires, Work Schedule Tolerance, Proportional Hazards Models, Twin Studies as Topic, Young Adult
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