Cross-national comparison of sex differences in health and mortality in Denmark, Japan and the US
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The present study aims to compare the direction and magnitude of sex differences in mortality and major health dimensions across Denmark, Japan and the US. The Human Mortality Database was used to examine sex differences in age-specific mortality rates. The Danish twin surveys, the Danish 1905-Cohort Study, the Health and Retirement Study, and the Nihon University Japanese Longitudinal Study of Aging were used to examine sex differences in health. Men had consistently higher mortality rates at all ages in all three countries, but they also had a substantial advantage in handgrip strength compared with the same-aged women. Sex differences in activities of daily living (ADL) became pronounced among individuals aged 85+ in all three countries. Depression levels tended to be higher in women, particularly, in Denmark and the HRS, and only small sex differences were observed in the immediate recall test and Mini-Mental State Exam. The present study revealed consistent sex differentials in survival and physical health, self-rated health and cognition at older ages, whereas the pattern of sex differences in depressive symptoms was country-specific.
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The limited findings on adulthood are inconsistent regarding both the magnitude and direction of the gender difference in depression.
“The limited findings in adulthood are inconsistent with respect to both the magnitude and direction of the gender difference in depression”
From Gender Differences in Depression in Representative National Samples: Meta-Analyses of Diagnoses and Symptoms (2017) · cites this paper as Oksuzyan et al., 2010
The Results (Depression) and Discussion describe variation by country and age, including a slight reversal in Japan that was not statistically significant. But the paper studies middle and older ages, not adulthood broadly, and its Discussion says the literature generally finds higher depression prevalence in women from young adulthood through early old age. It does not support characterizing the limited findings across adulthood as inconsistent in direction. (LLM, conf=0.84)
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Cites
Gender differences in depression: Critical review
Piccinelli, M., & Wilkinson, G. (2000) · British Journal of Psychiatry · doi:10.1192/bjp.177.6.486 · Cited by 2,376 · cited 1× · see citing works
“Although there is a mounting research literature pointing towards substantially higher prevalence of depression in women compared with men from young until early old age [53], the female predominance of depression at older ages is still debatable.”
BEBBINGTON, P. E., DUNN, G., JENKINS, R., LEWIS, G., BRUGHA, T., FARRELL, M., & MELTZER, H. (1998) · Psychological Medicine · doi:10.1017/s0033291797006077 · Cited by 330 · see citing works
Gender, cognitive decline, and risk of AD in older persons
Barnes, L. L., Wilson, R. S., Schneider, J. A., Bienias, J. L., Evans, D. A., & Bennett, D. A. (2003) · Neurology · doi:10.1212/01.wnl.0000065892.67099.2a · Cited by 173 · see citing works
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Self-citation
- Authors
- Oksuzyan, A., Crimmins, E., Saito, Y., O’Rand, A., Vaupel, J. W., & Christensen, K.
- Affiliations
- University of Southern Denmark (DK)
- University of Southern California (US)
- Nihon University (JP)
- Duke University (US)
- Max Planck Institute for Demographic Research (DE)
- Corresponding author
- Oksuzyan, Anna
- Venue
- European Journal of Epidemiology
- Published
- 2010-05-22
- Volume
- 25
- Issue
- 7
- Pages
- 471-480
- ISSN
- 0393-2990 (ISSN-L)
- 1573-7284
- PMC
- PMC2903692
- OpenAlex
- W2078760304
- Cited by
- 114
- References
- 3
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 9 · 2023: 8 · 2022: 8 · 2021: 5 · 2020: 9 · 2019: 9 · 2018: 7 · 2017: 8 · 2016: 7 · 2015: 12 · 2014: 9 · 2013: 5 · 2012: 3
- FWCI
- 5.73
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- European Journal of Epidemiology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- DukeSpace (Duke University) (submittedVersion, cc-by-nc-nd)
- Publikationen an der Universität Bielefeld (Universität Bielefeld) (submittedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Trinity's Access to Research Output (TARA) (Trinity College Dublin) (submittedVersion)
- Funders
- Velux Stiftung
- Nihon University
- Ministry of Education, Culture, Sports, Science and Technology
- National Institute on Aging (P30 AG17265, P01AG008761, P01AG031719, P01-AG007940, P30AG017265, U01AG009740, P30AG034424)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R03HD050374)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Social Sciences › Health › Health disparities and outcomes
- Social Sciences › Sociology and Political Science › Gender, Health, and Social Inequality
- Keywords
- sex differences, mortality, aging, grip strength, activities of daily living, depression, cognitive function, self-rated health, cross-national comparison, Denmark, Japan, United States, older adults
- MeSH terms
- Aged, Aged, 80 and over, Denmark, Disability Evaluation, Female, Health Status, Humans, Japan, Male, Middle Aged, Mortality, United States, Sex Distribution
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