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The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma
Abstract
Thermotherapy using magnetic nanoparticles is a new technique for interstitial hyperthermia and thermoablation based on magnetic field-induced excitation of biocompatible superparamagnetic nanoparticles. To evaluate the potential of this technique for minimally invasive treatment, we carried out a systematic analysis of its effects on experimental glioblastoma multiforme in a rat tumor model. Tumors were induced by implantation of RG-2-cells into the brains of 120 male Fisher rats. Animals were randomly allocated to 10 groups of 12 rats each, including controls. Animals received two thermotherapy treatments following a single intratumoral injection of two different magnetic fluids (dextran- or aminosilane-coated iron-oxide nanoparticles). Treatment was carried out on days four and six after tumor induction using an alternating magnetic field applicator system operating at a frequency of 100 kHz and variable field strength of 0-18 kA/m. The effectiveness of treatment was determined by the survival time of the animals and histopathological examinations of the brain and the tumor.Thermotherapy with aminosilane-coated nanoparticles led up to 4.5-fold prolongation of survival over controls, while the dextran-coated particles did not indicate any advantage. Intratumoral deposition of the aminosilane-coated particles was found to be stable, allowing for serial thermotherapy treatments without repeated injection. Histological and immunohistochemical examinations after treatment revealed large necrotic areas close to particle deposits, a decreased proliferation rate and a reactive astrogliosis adjacent to the tumor.Thus, localized interstitial thermotherapy with magnetic nanoparticles has an antitumoral effect on malignant brain tumors. This method is suitable for clinical use and may be a novel strategy for treating malignant glioma, which cannot be treated successfully today. The optimal treatment schedules and potential combinations with other therapies need to be defined in further studies.
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“In addition, MRI for evaluation of tumor progression cannot be properly performed after MFH, because of the artifacts caused by the very high amounts of SPION that accumulate in the lesion [219].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [219]
Citations
Cites
Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma
Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., Belanger, K., Brandes, A. A., Marosi, C., Bogdahn, U., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043330 · Cited by 21,807
Hyperthermia in combined treatment of cancer
Wust, P., Hildebrandt, B., Sreenivasa, G., Rau, B., Gellermann, J., Riess, H. B., FELIX, R., & Schlag, P. (2002) · The Lancet Oncology · doi:10.1016/s1470-2045(02)00818-5 · Cited by 2,002
Self-citationThe cellular and molecular basis of hyperthermia
Hildebrandt, B. (2002) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(01)00179-2 · Cited by 1,714
Johannsen, M., Gneveckow, U., Eckelt, L., Feussner, A., Waldöfner, N., Scholz, R., Değer, S., Wust, P., Loening, S. A., & Jordan, A. (2005) · International Journal of Hyperthermia · doi:10.1080/02656730500158360 · Cited by 802
Self-citationJordan, A., Wust, P., Fählin, H., John, W., Hinz, A., & FELIX, R. (1993) · International Journal of Hyperthermia · doi:10.3109/02656739309061478 · Cited by 694
Self-citationMagnetically mediated hyperthermia: current status and future directions
Moroz, P., Jones, S. K., & Gray, B. N. (2002) · International Journal of Hyperthermia · doi:10.1080/02656730110108785 · Cited by 538
Jordan, A., Scholz, R., Wust, P., Schirra, H., Schiestel, T., Schmidt, H., & Felix, R. (1999) · Journal of Magnetism and Magnetic Materials · doi:10.1016/s0304-8853(98)00558-7 · Cited by 521
Self-citationBarth, R. F. (1998) · Journal of Neuro-Oncology · doi:10.1023/a:1005805203044 · Cited by 358
Effects of Magnetic Fluid Hyperthermia (MFH) on C3H mammary carcinomain vivo
Jordan, A., Scholz, R., Wust, P., Fähling, H., Krause, J., Wlodarczyk, W., Sander, B., Vogl, T., & FELIX, R. (1997) · International Journal of Hyperthermia · doi:10.3109/02656739709023559 · Cited by 325
Self-citationIntracellular Hyperthermia for Cancer Using Magnetite Cationic Liposomes: An in vivo Study
Yanase, M., Shinkai, M., Honda, H., Wakabayashi, T., Yoshida, J., & Kobayashi, T. (1998) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1998.tb00586.x · Cited by 322
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Items 101–200 of 454
Synthesis and characterization of Fe3O4 nanoparticles with perspectives in biomedical applications
Mamani, J. B., Gamarra, L. F., & Brito, G. E. D. S. (2014) · Materials Research · doi:10.1590/s1516-14392014005000050 · Cited by 107
Salloum, M., Ma, R., & Zhu, L. K. (2009) · International Journal of Hyperthermia · doi:10.1080/02656730902803118 · Cited by 107
Chertok, B., Cole, A. J., David, A. E., & Yang, V. C.-M. (2009) · Molecular Pharmaceutics · doi:10.1021/mp900161h · Cited by 103
Soleymani, M., Khalighfard, S., Khodayari, S., Khodayari, H., Kalhori, M. R., Hadjighassem, M., Shaterabadi, Z., & Alizadeh, A. M. (2020) · Scientific Reports · doi:10.1038/s41598-020-58605-3 · Cited by 103
Application of Nanoparticles and Nanomaterials in Thermal Ablation Therapy of Cancer
Ashikbayeva, Z., Tosi, D., Balmassov, D., Schena, E., Saccomandi, P., & Inglezakis, V. J. (2019) · Nanomaterials · doi:10.3390/nano9091195 · Cited by 105
Engineering multifunctional nanoparticles: all‐in‐one versus one‐for‐all
Huynh, E., & Zheng, G. (2013) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1217 · Cited by 102
Use of nanoparticles for drug delivery in glioblastoma multiforme
Jain, K. K. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.4.363 · Cited by 99
Drug Delivery Nanosystems for the Localized Treatment of Glioblastoma Multiforme
Nam, L. V., Coll, C., Erthal, L. C. S., de la Torre, C., Serrano, D. R., Martínez‐Máñez, R., Santos-Martínez, M. J., & Ruiz‐Hernández, E. (2018) · Materials · doi:10.3390/ma11050779 · Cited by 107
Orringer, D. A., Koo, Y., Chen, T., Kopelman, R., Sagher, O., & Philbert, M. A. (2009) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2008.296 · Cited by 99
Evaluating Broader Impacts of Nanoscale Thermal Transport Research
Shi, L., Dames, C., Lukes, J. R., Reddy, P., Duda, J. C., Cahill, D. G., Lee, J., Marconnet, A. M., Goodson, K. E., Bahk, J., et al. (2015) · Nanoscale and Microscale Thermophysical Engineering · doi:10.1080/15567265.2015.1031857 · Cited by 97
Ostrowski, A., Nordmeyer, D., Boreham, A., Holzhausen, C., Mundhenk, L., Graf, C. M., Meinke, M. C., Vogt, A., Hadam, S., Lademann, J. M., et al. (2015) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.6.25 · Cited by 96
Dönmez, Ç. E. D., Manna, P. K., Nickel, R., Aktürk, S., & van Lierop, J. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b22600 · Cited by 95
Clinical magnetic hyperthermia requires integrated magnetic particle imaging
Healy, S., Bakuzis, A. F., Goodwill, P. W., Attaluri, A., Bulte, J. W. M., & Ivkov, R. (2022) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1779 · Cited by 95
Magnetic nanoparticle biodistribution following intratumoral administration
Giustini, A. J., Ivkov, R., & Hoopes, P. J. (2011) · Nanotechnology · doi:10.1088/0957-4484/22/34/345101 · Cited by 95
Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme
Aldoghachi, A. F., Aldoghachi, A. F., Breyne, K., Ling, K., & Cheah, P.-S. (2022) · Neuroscience · doi:10.1016/j.neuroscience.2022.03.030 · Cited by 96
Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs
Tesauro, D., Accardo, A., Aloj, L., Morelli, G., & Aurilio, M. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s53593 · Cited by 93
Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation
Carter, T. J., Agliardi, G., Lin, F., Ellis, M. J., Jones, C. L., Robson, M. P., Richard-Loendt, A., Southern, P., Lythgoe, M. F., Thin, M. Z., et al. (2021) · Small · doi:10.1002/smll.202005241 · Cited by 92
Stocke, N. A., Meenach, S. A., Arnold, S. M., Mansour, H. M., & Hilt, J. Z. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.12.050 · Cited by 91
Alphandéry, E., Idbaïh, A., Adam, C., Delattre, J., Schmitt, C., Guyot, F., & Chebbi, I. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.06.026 · Cited by 90
Tumor initiating cells in malignant gliomas: biology and implications for therapy
Hadjipanayis, C. G., & Meir, E. G. V. (2009) · Journal of Molecular Medicine · doi:10.1007/s00109-009-0440-9 · Cited by 92
Evolution of Magnetic Hyperthermia for Glioblastoma Multiforme Therapy
Gupta, R., & Sharma, D. (2019) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00652 · Cited by 89
Uptake and Metabolism of Iron Oxide Nanoparticles in Brain Cells
Petters, C., Irrsack, E., Koch, M., & Dringen, R. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1380-5 · Cited by 88
Williams, H. M. (2017) · Bioscience Horizons The International Journal of Student Research · doi:10.1093/biohorizons/hzx009 · Cited by 87
Bouras, A., Kaluzová, M., & Hadjipanayis, C. G. (2015) · Journal of Neuro-Oncology · doi:10.1007/s11060-015-1807-0 · Cited by 83
Stelter, L., Pinkernelle, J., Michel, R., Schwartländer, R., Raschzok, N., Morgül, M. H., Koch, M., Denecke, T., Ruf, J., Bäumler, H., et al. (2009) · Molecular Imaging and Biology · doi:10.1007/s11307-009-0237-9 · Cited by 81
Self-citationUptake of dimercaptosuccinate-coated magnetic iron oxide nanoparticles by cultured brain astrocytes
Geppert, M., Hohnholt, M. C., Thiel, K., Nürnberger, S., Grunwald, I., Rezwan, K., & Dringen, R. (2011) · Nanotechnology · doi:10.1088/0957-4484/22/14/145101 · Cited by 80
Magnetic fluid hyperthermia therapy for malignant brain tumors—an ethical discussion
Müller, S. (2009) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2009.01.011 · Cited by 78
Theranostics and contrast agents for magnetic resonance imaging
Jeong, Y., Hwang, H. S., & Na, K. (2018) · Biomaterials Research · doi:10.1186/s40824-018-0130-1 · Cited by 76
Therapeutics, imaging and toxicity of nanomaterials in the central nervous system.
Nunes, A., Al-Jamal, K. T., & Kostarelos, K. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.026 · Cited by 75
Progress in neuromodulation of the brain: A role for magnetic nanoparticles?
Roet, M., Hescham, S., Jahanshahi, A., Rutten, B. P. F., Anikeeva, P., & Temel, Y. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.03.002 · Cited by 77
Standardisation of magnetic nanoparticles in liquid suspension
Wells, J., Kazakova, O., Posth, O., Steinhoff, U., Petronis, Š., Bogart, L. K., Southern, P., Pankhurst, Q. A., & Johansson, C. (2017) · Journal of Physics D Applied Physics · doi:10.1088/1361-6463/aa7fa5 · Cited by 73
Hohnholt, M. C., Geppert, M., & Dringen, R. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.06.052 · Cited by 73
Nanotherapeutic systems for local treatment of brain tumors
Chakroun, R. W., Zhang, P., Lin, R., Schiapparelli, P. V., Quiñones‐Hinojosa, A., & Cui, H. (2017) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1479 · Cited by 80
Smart Magnetic Drug Delivery Systems for the Treatment of Cancer
Spoială, A., Ilie, C.-I., Motelică, L., Ficai, D., Semenescu, A., Oprea, O., & Ficai, A. (2023) · Nanomaterials · doi:10.3390/nano13050876 · Cited by 73
Multifunctional Fe3O4 nanoparticles for targeted bi-modal imaging of pancreatic cancer
Olariu, C. I., Yiu, H. H. P., Bouffier, L., Nedjadi, T., Costello, E., Williams, S. R., Halloran, C. M., & Rosseinsky, M. J. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm11370d · Cited by 71
Interaction of stable colloidal nanoparticles with cellular membranes
Mahmoudi, M., Meng, J., Xue, X., Liang, X. J., Rahman, M., Pfeiffer, C., Hartmann, R., Rivera-Gil, P., Pelaz, B., Parak, W. J., et al. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.11.012 · Cited by 74
Lak, A., Cassani, M., Binh, T., Winckelmans, N., Cabrera, D. M., Sadrollahi, E., Marras, S., Remmer, H., Fiorito, S., Cremades‐Jimeno, L., et al. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b02722 · Cited by 72
Bacterially synthesized ferrite nanoparticles for magnetic hyperthermia applications
Céspedes, E., Byrne, J. M., Farrow, N., Moise, S., Coker, V. S., Bencsik, M., Lloyd, J. R., & Telling, N. D. (2014) · Nanoscale · doi:10.1039/c4nr03004d · Cited by 70
McGill, S. L., Cuylear, C., Adolphi, N. L., Osiński, M., & Smyth, H. D. C. (2009) · IEEE Transactions on NanoBioscience · doi:10.1109/tnb.2009.2017292 · Cited by 70
Bio‐Nano‐Magnetic Materials for Localized Mechanochemical Stimulation of Cell Growth and Death
Kilinc, D., Dennis, C. L., & Lee, G. U. (2016) · Advanced Materials · doi:10.1002/adma.201504845 · Cited by 72
Nanomedicine and epigenome. Possible health risks
Smolková, B., Dušinská, M., & Gábelová, A. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.07.020 · Cited by 73
Alphandéry, E., Idbaïh, A., Adam, C., Delattre, J., Schmitt, C., Guyot, F., & Chebbi, I. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.07.020 · Cited by 68
Anticancer drug delivery with nanoparticles.
(2006) · PubMed · Cited by 68
Fighting fire with fire: the revival of thermotherapy for gliomas.
Titsworth, W. L., Murad, G. J. A., Hoh, B. L., & Rahman, M. (2014) · PubMed · Cited by 67
Numerical study of nanofluid infusion in deformable tissues for hyperthermia cancer treatments
Su, D., Ma, R., & Zhu, L. K. (2011) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-011-0819-y · Cited by 66
Engelmann, U. M., Roeth, A. A., Eberbeck, D., Buhl, E. M., Neumann, U. P., Schmitz‐Rode, T., & Slabu, I. (2018) · Scientific Reports · doi:10.1038/s41598-018-31553-9 · Cited by 66
Creixell, M., Herrera, A., Latorre‐Esteves, M., Ayala, V., Torres‐Lugo, M., & Rinaldi, C. (2010) · Journal of Materials Chemistry · doi:10.1039/c0jm01504k · Cited by 65
Kettering, M., Winter, J., Zeisberger, M., Bremer-Streck, S., Oehring, H., Bergemann, C., Alexiou, C., Hergt, R., Halbhuber, K. J., Kaiser, W. A., et al. (2007) · Nanotechnology · doi:10.1088/0957-4484/18/17/175101 · Cited by 65
Nanomaterial applications for neurological diseases and central nervous system injury
Huang, L., Hu, J., Huang, S., Wang, B. Z., Siaw-Debrah, F., Nyanzu, M. K., Zhang, Y., & Zhuge, Q. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.07.003 · Cited by 66
Kalber, T. L., Ordidge, K., Southern, P., Loebinger, M. R., Kyrtatos, P. G., Pankhurst, Q. A., Lythgoe, M. F., & Janes, S. M. (2016) · International Journal of Nanomedicine · doi:10.2147/ijn.s94255 · Cited by 64
Multi-scale study of nanoparticle transport and deposition in tissues during an injection process
Su, D., Ma, R., Salloum, M., & Zhu, L. K. (2010) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-010-0615-0 · Cited by 63
Tsiapa, I., Efthimiadou, E. Κ., Fragogeorgi, E. A., Loudos, G. K., Varvarigou, A. D., Bouziotis, P., Kordas, G. C., Mihailidis, D. N., Nikiforidis, G. C., Xanthopoulos, S., et al. (2014) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2014.07.032 · Cited by 63
Magnetic hyperthermia therapy in glioblastoma tumor on-a-Chip model
Mamani, J. B., Marinho, B. S., Rego, G. N. A., Nucci, M. P., Alvieri, F., dos Santos, R. S., Ferreira, J. V. M., Oliveira, F. A., & Gamarra, L. F. (2019) · Einstein (São Paulo) · doi:10.31744/einstein_journal/2020ao4954 · Cited by 62
Rego, G. N. A., Nucci, M. P., Mamani, J. B., Oliveira, F. A., Marti, L. C., Filgueiras, I. S., Ferreira, J. M., Real, C. C., Faria, D. D. P., Espinha, P., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030958 · Cited by 62
Ito, A., Saito, H., Mitobe, K., Minamiya, Y., Takahashi, N., Maruyama, K., Motoyama, S., Katayose, Y., & Ogawa, J. (2009) · Cancer Science · doi:10.1111/j.1349-7006.2008.01072.x · Cited by 61
Wu, Y., Lü, Z., Li, Y., Yang, J., & Zhang, X. (2020) · Nanomaterials · doi:10.3390/nano10081441 · Cited by 63
Shreyash, N., Sonker, M., Bajpai, S., & Tiwary, S. K. (2021) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c00020 · Cited by 61
Mannucci, S., Ghin, L., Conti, G., Tambalo, S., Lascialfari, A., Orlando, T., Benati, D., Bernardi, P., Betterle, N., Bassi, R., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108959 · Cited by 60
Magnetic hyperthermia enhance the treatment efficacy of peri-implant osteomyelitis
Fang, C.-H., Tsai, P.-I., Huang, S.-W., Sun, J.-S., Chang, J. Z., Shen, H.-H., Chen, S., Lin, F. H., Hsu, L.-T., & Yen-Chun, C. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2621-4 · Cited by 61
Nanoscale Materials for Tackling Brain Cancer: Recent Progress and Outlook
Rozhkova, E. A. (2011) · Advanced Materials · doi:10.1002/adma.201004714 · Cited by 58
Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma
Shevtsov, M. A., Yakovleva, L. Y., Nikolaev, B. P., Marchenko, Y., Добродумов, А. В., Onokhin, K., Onokhina, Y. S., Selkov, S. А., Михрина, А. Л., Guzhova, I. V., et al. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not141 · Cited by 58
Khan, A. A., Allemailem, K. S., Almatroudi, A., Almatroodi, S. A., Mahzari, A., Alsahli, M. A., & Rahmani, A. H. (2020) · Molecules · doi:10.3390/molecules25225336 · Cited by 60
Magnetic nanoparticles-based Drug and Gene Delivery Systems for the Treatment of Pulmonary Diseases
El-sherbiny, I. M., Elbaz, N. M., Sedki, M., Elgammal, A., & Yacoub, M. H. (2017) · Nanomedicine · doi:10.2217/nnm-2016-0341 · Cited by 57
Magnetic-mediated hyperthermia for cancer treatment: Research progress and clinical trials
Zhao, L., Liu, J., Ouyang, W., Li, D., Li, L., Li, L., & Tang, J. (2013) · Chinese Physics B · doi:10.1088/1674-1056/22/10/108104 · Cited by 56
Magnetic Nanoparticles: Synthesis, Surface Modifications and Application in Drug Delivery
Bucak, Ş., Yavuztürk, B., & Demir, A. (2012) · InTech eBooks · doi:10.5772/52115 · Cited by 56
Protein and polymer immobilized La0.7Sr0.3MnO3nanoparticles for possible biomedical applications
Bhayani, K. R., Kale, S. N., Arora, S., Rajagopal, R., Mamgain, H. P., Kaul-Ghanekar, R., Kundaliya, D. C., Kulkarni, S. D., Pasricha, R., Dhole, S. D., et al. (2007) · Nanotechnology · doi:10.1088/0957-4484/18/34/345101 · Cited by 56
LeBrun, A., Ma, R., & Zhu, L. K. (2016) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2016.06.025 · Cited by 53
Ullah, S., Seidel, K., Türkkan, S., Warwas, D. P., Dubich, T., Rohde, M., Häuser, H., Behrens, P. J., Kirschning, A., Köster, M., et al. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.12.040 · Cited by 53
Saito, H., Mitobe, K., Ito, A., Sugawara, Y., Maruyama, K., Minamiya, Y., Motoyama, S., Yoshimura, N., & Ogawa, J. (2008) · Cancer Science · doi:10.1111/j.1349-7006.2008.00726.x · Cited by 52
Mejías, R., Flores, P. H., Talelli, M., Tajada, J. L., Brollo, M. E. F., Portilla, Y., Morales, M. P., & Barber, D. F. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b18451 · Cited by 53
Rego, G. N. A., Mamani, J. B., Souza, T. K. F., Nucci, M. P., da Silva, H. R., & Gamarra, L. F. (2019) · Einstein (São Paulo) · doi:10.31744/einstein_journal/2019ao4786 · Cited by 52
Etemadi, H., Buchanan, J. K., Kandile, N. G., & Plieger, P. G. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00938 · Cited by 53
Ghosh, T., Teramoto, Y., & Katiyar, V. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b05905 · Cited by 51
Mandawala, C., Chebbi, I., Durand‐Dubief, M., Fèvre, R. L., Hamdous, Y., Guyot, F., & Alphandéry, E. (2017) · Journal of Materials Chemistry B · doi:10.1039/c6tb03248f · Cited by 49
Magnetic iron oxide nanogels for combined hyperthermia and drug delivery for cancer treatment
Patri, S. K., Thanh, N. T. K., & Kamaly, N. (2024) · Nanoscale · doi:10.1039/d4nr02058h · Cited by 49
Nanotechnology, from quantum mechanical calculations up to drug delivery
Szefler, B. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s172907 · Cited by 48
Wu, S. Y.-H., Tseng, C., & Lin, F. (2009) · Journal of Nanoparticle Research · doi:10.1007/s11051-009-9734-7 · Cited by 48
The role of hyperthermia in the treatment of tumor
Zhu, W., Pan, S., Zhang, J., Xu, J., Zhang, Y., Zhang, Y., Fu, Z., Wang, Y., Xu, Z., & Xu, Z. (2024) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2024.104541 · Cited by 51
Al-Ahmady, Z. S., Lozano, N., Mei, K., Al-Jamal, W. T., & Kostarelos, K. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.09.009 · Cited by 47
Revolutionary Impact of Nanodrug Delivery on Neuroscience
Khanbabaie, R., & Jahanshahi, M. (2012) · Current Neuropharmacology · doi:10.2174/157015912804499456 · Cited by 47
Itô, A., & Kobayashi, T. (2008) · Thermal Medicine · doi:10.3191/thermalmed.24.113 · Cited by 47
Nanoparticles for the treatment of osteoporosis
Vallet‐Regí, M., Mora‐Raimundo, P., & Manzano, M. (2017) · AIMS bioengineering · doi:10.3934/bioeng.2017.2.259 · Cited by 46
Sardoiwala, M. N., Kaundal, B., & Choudhury, S. R. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813351-4.00038-9 · Cited by 49
Thermoseeds for interstitial magnetic hyperthermia: from bioceramics to nanoparticles
Baeza, A., Arcos, D., & Vallet‐Regí, M. (2013) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/25/48/484003 · Cited by 47
Bruners, P., Braunschweig, T. A., Hodenius, M., Pietsch, H., Penzkofer, T., Baumann, M., Günther, R. W., Schmitz‐Rode, T., & Mahnken, A. H. (2009) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-009-9583-x · Cited by 45
Towards new therapeutic approaches for malignant melanoma
Pacheco, I., Buzea, C., & Tron, V. A. (2011) · Expert Reviews in Molecular Medicine · doi:10.1017/s146239941100202x · Cited by 47
The cytotoxicity evaluation of magnetic iron oxide nanoparticles on human aortic endothelial cells
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Metadata
- Authors
- Jordan, A., Scholz, R., Maier-Hauff, K., van Landeghem, F. K. H., Waldoefner, N., Teichgraeber, U., Pinkernelle, J., Bruhn, H., Neumann, F., Thiesen, B., von Deimling, A., & Felix, R.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- Corresponding author
- Jordan, Andreas
- ORCID
- Bruhn, Harald
- Venue
- Journal of Neuro-Oncology
- Published
- 2005-11-29
- Volume
- 78
- Issue
- 1
- Pages
- 7-14
- ISSN
- 0167-594X (ISSN-L)
- 1573-7373
- OpenAlex
- W2093807603
- Cited by
- 459
- References
- 23
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 11 · 2023: 17 · 2022: 19 · 2021: 30 · 2020: 23 · 2019: 20 · 2018: 31 · 2017: 30 · 2016: 20 · 2015: 28 · 2014: 32 · 2013: 29 · 2012: 28
- FWCI
- 10.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Neuro-Oncology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- European Regional Development Fund
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
- Physical Sciences › Engineering › Biomedical Engineering › Ultrasound and Hyperthermia Applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- magnetic nanoparticles, heat therapy, glioblastoma, high-grade glioma, interstitial hyperthermia, thermal ablation, superparamagnetic iron oxide nanoparticles, dextran-coated nanoparticles, alternating magnetic field, intratumoral injection, tumor necrosis, astrocyte activation, rat tumor model, survival
- MeSH terms
- Animals, Brain Neoplasms, Glioma, Hyperthermia, Induced, Immunohistochemistry, Magnetic Resonance Imaging, Magnetics, Male, Rats, Inbred F344, Survival Analysis, Nanostructures, Rats
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