Cited by 400Psychosomatic Disorders and Their TreatmentsNeural and Behavioral Psychology StudiesNeuroscience and Music Perception

The DOI matches its Crossref record; 136 of the 136 references it cites were found in a registry or an index.

Contributions of the Insula to Cognition and Emotion

Gasquoine, Philip Gerard·2014·Neuropsychology Review

DOI 10.1007/s11065-014-9246-9

Open this paper in CoChat — free account

Abstract

Historically, the insula was considered primary gustatory cortex. Now it is known to play a more comprehensive role in the processing of sensory information, including acting as primary cortex for interoceptive information, including autonomic nervous system mediated changes. As such, it is critical for emotional feeling in accord with the James-Lange theory, a role previously ascribed to the limbic system. Neuroimaged abnormal grey matter volumes or activity levels in the insula have been associated with schizophrenia, eating disorders, anxiety and mood disorders, conduct disorder, autism, addiction, and chronic pain. The significance of these abnormal activity patterns remains theoretical. Neuropsychological studies have linked dominant insula injury with various symptoms of aphasia, but its exact role in language processing remains uncertain as most cases involve lesions that extend into perisylvian language zones. Functional neuroimaging studies have found insula hyper-activations, typically in conjunction with anterior cingulate cortex, for all manner of experimental tasks including those involving perception, intentional action, and consciousness. Such neuroimaged activity is unlikely to be task-specific, but rather reflective of generic changes in autonomic activity in response to salience, homeostatic incongruence, or cognitive challenge.

Integrity signals

Registry

Crossref · 10.1007/s11065-014-9246-9

Cites

136 of 136 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The expression of the emotions in man and animals.
Darwin, C. D. (1872) · J. Murray eBooks · doi:10.1037/10001-000 · Cited by 12,120
Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5587-06.2007 · Cited by 7,426
How do you feel — now? The anterior insula and human awareness
(Bud) Craig, A. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2555 · Cited by 6,657 · cited 1×
“Five studies in Table 1 implicated the insula in conscious awareness including Craig ( 2009 ) , Medford and Critchley ( 2010 ) , and Menon and Uddin ( 2010 ) , but the issue remains contentious .”
Background
Brain magnetic resonance imaging with contrast dependent on blood oxygenation.
Ogawa, S., Lee, T. M., Kay, A. R., & Tank, D. W. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.24.9868 · Cited by 6,483
Saliency, switching, attention and control: a network model of insula function
Menon, V., & Uddin, L. Q. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0262-0 · Cited by 5,592
Constants across cultures in the face and emotion.
Ekman, P., & Friesen, W. V. (1971) · Journal of Personality and Social Psychology · doi:10.1037/h0030377 · Cited by 5,509
What we can do and what we cannot do with fMRI
Logothetis, N. K. (2008) · Nature · doi:10.1038/nature06976 · Cited by 3,612
A PROPOSED MECHANISM OF EMOTION
PAPEZ, J. W. (1937) · Archives of Neurology And Psychiatry · doi:10.1001/archneurpsyc.1937.02260220069003 · Cited by 3,563
II.—WHAT IS AN EMOTION ?
JAMES, W. (1884) · Mind · doi:10.1093/mind/os-ix.34.188 · Cited by 3,446
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406

Flagged first, then by citations

Show all 136 references

Research works printed but not linked: 3

Reil, J. C. (1809). Die sylvische Grube. Archiv für die Physiologie, 9, 195–208.
Rose, M. (1928). Die Inselrinde des Menschen und der Tiere. Journal für Psychologie und Neurologie, 37, 470–624.
Wernicke, C. (1874). Der aphasiche Symptomenkomplex: Eine Psychologische Studie auf Anatomischer Basis. Breslau: Cohn & Weigart.

Sorted by citations

Understanding Emotions: Origins and Roles of the Amygdala
Šimić, G., Tkalčić, M., Vukić, V., Mulc, D., Španić, E., Šagud, M., Olucha-Bordonau, F. E., Vukšić, M., & Hof, P. R. (2021) · Biomolecules · doi:10.3390/biom11060823 · Cited by 631
Dynamic Resting-State Functional Connectivity in Major Depression
Kaiser, R. H., Whitfield-Gabrieli, S., Dillon, D. G., Goer, F., Beltzer, M., Minkel, J., Smoski, M., Dichter, G., & Pizzagalli, D. A. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.352 · Cited by 438
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Schmaal, L., van Harmelen, A.-L., Chatzi, V., Lippard, E. T. C., Toenders, Y. J., Averill, L. A., Mazure, C. M., & Blumberg, H. P. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0587-x · Cited by 373
Brain default-mode network dysfunction in addiction
Zhang, R., & Volkow, N. D. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.06.036 · Cited by 386
The neuroscience of positive emotions and affect: Implications for cultivating happiness and wellbeing
Alexander, R., Aragón, O. R., Bookwala, J., Cherbuin, N., Gatt, J. M., Kahrilas, I. J., Kästner, N., Lawrence, A. B., Lowe, L. J., Morrison, R., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.12.002 · Cited by 364
Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity
Gilbert, J. P., & Man, H. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00359 · Cited by 286
The neurobiology of emotion regulation in posttraumatic stress disorder: amygdala downregulation via real‐time fMRI neurofeedback
Nicholson, A. A., Rabellino, D., Densmore, M., Frewen, P. A., Paret, C., Kluetsch, R., Schmahl, C., Théberge, J., Neufeld, R. W. J., McKinnon, M. C., et al. (2017) · Human Brain Mapping · doi:10.1002/hbm.23402 · Cited by 273
Sensory, emotional and cognitive contributions to anxiety in autism spectrum disorders
South, M., & Rodgers, J. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00020 · Cited by 270
“Insula cortex is critical for integration of interoceptive and sensory information and regulating emotional response (Gasquoine, 2014).”
Background
A review of definitions of fatigue – And a step towards a whole definition
Phillips, R. O. (2015) · Transportation Research Part F Traffic Psychology and Behaviour · doi:10.1016/j.trf.2015.01.003 · Cited by 279
Altered Coupling Between Resting-State Cerebral Blood Flow and Functional Connectivity in Schizophrenia
Zhu, J., Zhuo, C., Xu, L., Liu, F., Qin, W., & Yu, C. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx051 · Cited by 152
Tai Chi Chuan and Baduanjin practice modulates functional connectivity of the cognitive control network in older adults
Tao, J., Chen, X., Egorova, N., Liu, J., Xue, X., Wang, Q., Zheng, G., Li, M., Hong, W., Sun, S., et al. (2017) · Scientific Reports · doi:10.1038/srep41581 · Cited by 147
A systematic review of the neural bases of psychotherapy for anxiety and related disorders
Brooks, S. J., & Stein, D. J. (2015) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2015.17.3/sbrooks · Cited by 134
The Insula: A Brain Stimulation Target for the Treatment of Addiction
Ibrahim, C., Rubin-Kahana, D. S., Pushparaj, A., Musiol, M., Blumberger, D. M., Daskalakis, Z. J., Zangen, A., & Le Foll, B. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00720 · Cited by 133
Unique insula subregion resting-state functional connectivity with amygdala complexes in posttraumatic stress disorder and its dissociative subtype.
Nicholson, A. A., Sapru, I., Densmore, M., Frewen, P. A., Neufeld, R. W. J., Théberge, J., McKinnon, M. C., & Lanius, R. A. (2016) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2016.02.002 · Cited by 128
The Developing Brain in the Digital Era: A Scoping Review of Structural and Functional Correlates of Screen Time in Adolescence
Marciano, L., Camerini, A.-L., & Morese, R. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.671817 · Cited by 139
Shared Reading Quality and Brain Activation during Story Listening in Preschool-Age Children
Hutton, J. S., Phelan, K., Horowitz-Kraus, T., Dudley, J., Altaye, M., DeWitt, T., & Holland, S. K. (2017) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2017.08.037 · Cited by 105
Intact brain processing of musical emotions in autism spectrum disorder, but more cognitive load and arousal in happy vs. sad music
Gebauer, L., Skewes, J., Westphael, G., Heaton, P. F., & Vuust, P. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00192 · Cited by 111
Transcranial Magnetic Stimulation of Left Dorsolateral Prefrontal Cortex Induces Brain Morphological Changes in Regions Associated with a Treatment Resistant Major Depressive Episode: An Exploratory Analysis
Lan, M. J., Chhetry, B. T., Liston, C., Mann, J. J., & Dubin, M. (2016) · Brain Stimulation · doi:10.1016/j.brs.2016.02.011 · Cited by 96
Modulation of Distinct Intrinsic Resting State Brain Networks by Acute Exercise Bouts of Differing Intensity
Schmitt, A. G., Upadhyay, N., Martin, J. A., Rojas, S., Strüder, H. K., & Boecker, H. (2019) · Brain Plasticity · doi:10.3233/bpl-190081 · Cited by 97
Oxytocin selectively facilitates learning with social feedback and increases activity and functional connectivity in emotional memory and reward processing regions
Hu, J., Qi, S., Becker, B., Luo, L., Gao, S., Gong, Q., Hurlemann, R., & Kendrick, K. M. (2015) · Human Brain Mapping · doi:10.1002/hbm.22760 · Cited by 98
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology
Orosco, L. A., Ross, A. P., Cates, S. L., Scott, S. E., Wu, D., Sohn, J., Pleasure, D., Pleasure, S. J., Adamopoulos, I. E., & Zarbalis, K. S. (2014) · Nature Communications · doi:10.1038/ncomms5692 · Cited by 90
The neural correlates of happiness: A review of PET and fMRI studies using autobiographical recall methods
Suardi, A. C., Sotgiu, I., Costa, T., Cauda, F., & Rusconi, M. L. (2016) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-016-0414-7 · Cited by 91
Does Olfactory Training Improve Brain Function and Cognition? A Systematic Review
Vance, D. E., Bene, V. A. D., Kamath, V. J., Sandson, J., Billings, R., Cho, D., Byun, J. Y., Jacob, A. E., Anderson, J. N., Visscher, K., et al. (2023) · Neuropsychology Review · doi:10.1007/s11065-022-09573-0 · Cited by 98
A neurobehavioral approach to addiction: implications for the opioid epidemic and the psychology of addiction
Bechara, A., Berridge, K. C., Bickel, W. K., Morón, J. A., Williams, S. B., & Stein, J. S. (2019) · Psychological Science in the Public Interest · doi:10.1177/1529100619860513 · Cited by 82
Differential insular cortex sub-regional atrophy in neurodegenerative diseases: a systematic review and meta-analysis
Fathy, Y. Y., Hoogers, S. E., Berendse, H. W., van der Werf, Y. D., Visser, P. J., de Jong, F. J., & van de Berg, W. D. J. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00099-3 · Cited by 82
Continuous vs. intermittent neurofeedback to regulate auditory cortex activity of tinnitus patients using real-time fMRI - A pilot study
Emmert, K., Kopel, R., Koush, Y., Maire, R., Senn, P., Ville, D. V. D., & Haller, S. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.12.023 · Cited by 81
Prenatal Neurogenesis in Autism Spectrum Disorders
Kaushik, G., & Zarbalis, K. S. (2016) · Frontiers in Chemistry · doi:10.3389/fchem.2016.00012 · Cited by 80
Anterior insula reflects surprise in value-based decision-making and perception
Loued-Khenissi, L., Pfeuffer, A., Einhäuser, W., & Preuschoff, K. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116549 · Cited by 66
Computerized cognitive training for Chinese mild cognitive impairment patients: A neuropsychological and fMRI study
Li, B., He, N., Qiao, Y., Xu, H., Lu, Y., Cui, P., Ling, H., Yan, F.-H., Tang, H., & Chen, S. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101691 · Cited by 85
Structural and Functional Alterations in Right Dorsomedial Prefrontal and Left Insular Cortex Co-Localize in Adolescents with Aggressive Behaviour: An ALE Meta-Analysis
Raschle, N. M., Menks, W. M., Fehlbaum, L. V., Tshomba, E., & Stadler, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136553 · Cited by 79
Brain responses to drug cues predict craving changes in abstinent heroin users: A preliminary study
Liu, S., Wang, S., Zhang, M., Xu, Y., Shao, Z., Chen, L., Yang, W., Liu, J., & Yuan, K. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118169 · Cited by 69
Common and Specific Functional Activity Features in Schizophrenia, Major Depressive Disorder, and Bipolar Disorder
Yang, Y., Liu, S., Jiang, X., Yu, H., Ding, S., Lu, Y., Li, W., Zhang, H., Liu, B., Cui, Y. J., et al. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00052 · Cited by 66
Glioma surgery with awake language mapping versus generalized anesthesia: a systematic review
Bu, L., Zhang, J., Lu, J., & Wu, J. (2020) · Neurosurgical Review · doi:10.1007/s10143-020-01418-9 · Cited by 71
The Cambridge Handbook of Substance and Behavioral Addictions
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591 · Cited by 64
Hurst Exponent Analysis of Resting-State fMRI Signal Complexity across the Adult Lifespan
Dong, J. Z., Jing, B., Ma, X., Liu, H., Mo, X., & Li, J. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00034 · Cited by 61
The thalamus is the causal hub of intervention in patients with major depressive disorder: Evidence from the Granger causality analysis
Yang, C., Xiao, K., Ao, Y., Cui, Q., Jing, X., & Wang, Y. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103295 · Cited by 62
Specific Changes in Brain Activity during Urgency in Women with Overactive Bladder after Successful Sacral Neuromodulation: A Functional Magnetic Resonance Imaging Study
Weissbart, S. J., Bhavsar, R., Rao, H., Wein, A. J., Detre, J. A., Arya, L. A., & Smith, A. L. (2018) · The Journal of Urology · doi:10.1016/j.juro.2018.03.129 · Cited by 60
Deep TMS of the insula using the H-coil modulates dopamine release: a crossover [11C] PHNO-PET pilot trial in healthy humans
Malik, S., Jacobs, M., Cho, S.-S., Boileau, I., Blumberger, D., Heilig, M., Wilson, A., Daskalakis, Z. J., Strafella, A. P., Zangen, A., et al. (2018) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9800-1 · Cited by 58
Restoring the missing person to personalized medicine and precision psychiatry
Gómez-Carrillo, A., Paquin, V., Dumas, G., & Kirmayer, L. J. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1041433 · Cited by 64
Awake craniotomy versus craniotomy under general anesthesia for the surgical treatment of insular glioma: choices and outcomes
Gravesteijn, B. Y., Keizer, M. E., Vincent, A. J. P. E., Schouten, J. W., Stolker, R. J., & Klimek, M. (2017) · Neurological Research · doi:10.1080/01616412.2017.1402147 · Cited by 60
Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes
Popovic, D., Ruef, A., Dwyer, D., Antonucci, L. A., Eder, J., Sanfelici, R., Kambeitz‐Ilankovic, L., Oztuerk, O. F., Dong, M. S., Paul, R., et al. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.05.020 · Cited by 61
Insular epilepsy surgery
Laoprasert, P., Ojemann, J. G., & Handler, M. H. (2017) · Epilepsia · doi:10.1111/epi.13682 · Cited by 57
Longitudinal effects of cognitive behavioral therapy for depression on the neural correlates of emotion regulation
Rubin-Falcone, H., Weber, J., Kishon, R., Ochsner, K., Delaparte, L., Doré, B., Zanderigo, F., Oquendo, M. A., Mann, J. J., & Miller, J. M. (2018) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2017.11.002 · Cited by 53
Neuroinflammation and neuroprogression in depression: Effects of alternative drug treatments
Richardson, B., MacPherson, A., & Bambico, F. R. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100554 · Cited by 57
Neurogenic Background for Emotional Stress-Associated Hypertension
Fontes, M. A. P., Marins, F. R., Patel, T., de Paula, C. A., Machado, L. R. D. S., Lima, É. B. D. S., de Godoy, A. C. V., Viana, A. C. R., Linhares, I. C. S., Xavier, C. H., et al. (2023) · Current Hypertension Reports · doi:10.1007/s11906-023-01235-7 · Cited by 63
Task-positive and task-negative networks and their relation to depression: EEG beamformer analysis
Knyazev, G. G., Savostyanov, A. N., Bocharov, A. V., Tamozhnikov, S. S., & Сапрыгин, А. Е. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.03.033 · Cited by 54
High-sensitivity neuroimaging biomarkers for the identification of amnestic mild cognitive impairment based on resting-state fMRI and a triple network model
Yu, E., Liao, Z., Tan, Y., Qiu, Y., Zhu, J., Zhang, H., Wang, J., Wang, X., Wang, H., Chen, Y., et al. (2017) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9727-6 · Cited by 51
Task-positive and task-negative networks in major depressive disorder: A combined fMRI and EEG study
Knyazev, G. G., Savostyanov, A. N., Bocharov, A. V., Brak, I. V., Osipov, E. A., Filimonova, E., Сапрыгин, А. Е., & Aftanas, L. I. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.003 · Cited by 53
Obstructive sleep apnea during REM sleep and daytime cerebral functioning: A regional cerebral blood flow study using high-resolution SPECT
Baril, A., Gagnon, K., Brayet, P., Montplaisir, J. Y., Carrier, J., Soucy, J., Lafond, C., Blais, H., d'Aragon, C., Gagnon, J., et al. (2018) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x18814106 · Cited by 50
Altered neural processing of negative stimuli in people with internet gaming disorder: fMRI evidence from the comparison with recreational game users
Zhang, J., Dong, H., Zhao, Z., Chen, S., Jiang, Q. Y., Du, X., & Dong, G. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.01.008 · Cited by 49
Behavioral Economic Considerations of Novel Addictions and Nonaddictive Behavior: Research and Analytic Methods
Reed, D. D., Naudé, G. P., Gelino, B. W., & Amlung, M. T. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.011 · Cited by 48
Functional connectivity gradients of the insula to different cerebral systems
Wang, R., Mo, F., Shen, Y., Song, Y., Cai, H., & Zhu, J. (2022) · Human Brain Mapping · doi:10.1002/hbm.26099 · Cited by 50
Neuropathological sequelae of Human Immunodeficiency Virus and apathy: A review of neuropsychological and neuroimaging studies
McIntosh, R. C., Rosselli, M., Uddin, L. Q., & Antoni, M. H. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.008 · Cited by 53
Cognition and Related Neural Findings on Methamphetamine Use Disorder: Insights and Treatment Implications From Schizophrenia Research
Guerin, A. A., Bonomo, Y. A., Lawrence, A. J., Baune, B. T., Nestler, E. J., Rossell, S. L., & Kim, J. H. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00880 · Cited by 50
Cytoarchitecture, probability maps and segregation of the human insula
Quabs, J., Caspers, S., Schöne, C., Mohlberg, H., Bludau, S., Dickscheid, T., & Amunts, K. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119453 · Cited by 46
The Prevention and Treatment of Gambling Disorders: Some Art, Some Science
Derevensky, J. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.024 · Cited by 45
Resting State Functional Connectivity Biomarkers of Treatment Response in Mood Disorders: A Review
Taylor, J. J., Kurt, H. G., & Anand, A. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.565136 · Cited by 50
Considering the Overlap and Nonoverlap of Compulsivity, Impulsivity, and Addiction
Blum, A. W., & Grant, J. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.038 · Cited by 44
Neurobiological Foundations of Behavioral Addictions
Vaccaro, A. G., & Potenza, M. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.016 · Cited by 45
Neurobiology of Substance Addictions
Christie, N. C., & Bechara, A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.015 · Cited by 44
Sensitization of Incentive Salience and the Transition to Addiction
Warlow, S. M., Baumgartner, H. M., Freeland, C. M., Naffziger, E. E., Olney, J. J., Berridge, K. C., & Robinson, M. J. F. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.006 · Cited by 46
Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa
McAdams, C. J., Jeon-Slaughter, H., Evans, S., Lohrenz, T., Montague, P. R., & Krawczyk, D. C. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw092 · Cited by 40
Neural correlates of effort-dependent and effort-independent cognitive fatigue components in patients with multiple sclerosis
Spiteri, S., Hassa, T., Claros-Salinas, D., Dettmers, C., & Schoenfeld, M. A. (2017) · Multiple Sclerosis Journal · doi:10.1177/1352458517743090 · Cited by 45
Pain Asymbolia as Depersonalization for Pain Experience. An Interoceptive Active Inference Account
Gerrans, P. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.523710 · Cited by 43
“Although it is not the only channel for bodily signaling, its role as a primary integrative hub of interoceptive afferents makes PIC a crucial substrate of the experience of material me (Singer et al., 2009; Medford and Critchley, 2010; Gasquoine, 2014; Moayedi, 2014).”
Background
Mindfulness-Based Interventions Applied to Addiction Treatments
Kechter, A., & Black, D. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.040 · Cited by 43
Multiple Memory Systems, Addiction, and Health Habits: New Routes for Translational Science
Stacy, A. W., Pike, J. R., & Lee, A. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.017 · Cited by 43
Tanning as an Addiction: The State of the Research and Implications for Intervention
Miller, K. A., & Mays, D. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.037 · Cited by 43
Food versus Eating Addictions
Schulte, E. M., Schiestl, E. T., & Gearhardt, A. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.035 · Cited by 43
Behavioral Economics and Addictive Disorders
Jarmolowicz, D. P., & Schneider, T. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.005 · Cited by 42
Prevention and Treatment of Compulsive Buying Disorder
Galimov, A., & Black, D. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.027 · Cited by 42
Precision Behavioral Management (PBM): A Novel Genetically Guided Therapy to Combat Reward Deficiency Syndrome (RDS) Relevant to the Opiate Crisis
Blum, K., Roy, A. K., Podesta, A., Modestino, E. J., Steinberg, B., Gondré-Lewis, M. C., Baron, D. A., Thanos, P. K., Lott, L., Badgaiyan, S., et al. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.031 · Cited by 42
Prevention and Treatment of “Food Addiction”
Davis, C., & Mason, A. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.023 · Cited by 42
Human Neurobiological Approaches to Hedonically Motivated Behaviors
Burger, K. S., Shearrer, G. E., & Sadler, J. R. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.009 · Cited by 42
Feedback Models for Gambling Control: The Use and Efficacy of Online Responsible Gambling Tools
Griffiths, M. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.034 · Cited by 42
Connecting Circuits with Networks in Addiction Neuroscience: A Salience Network Perspective
Cushnie, A. K., Tang, W., & Heilbronner, S. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24109083 · Cited by 47
Blissfully unaware: Anosognosia and anosodiaphoria after acquired brain injury
Gasquoine, P. G. (2015) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2015.1011665 · Cited by 48
Hearing voices in the head: Two meta-analyses on structural correlates of auditory hallucinations in schizophrenia
Romeo, Z., & Spironelli, C. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103241 · Cited by 41
Cognitive and neuroimaging correlates of financial exploitation vulnerability in older adults without dementia: Implications for early detection of Alzheimer’s disease
Fenton, L. E., Weissberger, G. H., Boyle, P. A., Mosqueda, L. A., Yassine, H. N., Nguyen, A. L., Lim, A. C., & Han, S. D. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104773 · Cited by 46
White matter correlates of anxiety sensitivity in panic disorder
Kim, M., Kim, B., Choi, T. K., & Lee, S. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.08.043 · Cited by 41
Monoamine signaling and neuroinflammation: mechanistic connections and implications for neuropsychiatric disorders
Saggu, S., Pless, A., Dew, E., Ware, D., Jiao, K., & Wang, Q. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1543730 · Cited by 45
Association between use of systemic and inhaled glucocorticoids and changes in brain volume and white matter microstructure: a cross-sectional study using data from the UK Biobank
van der Meulen, M., Amaya, J. M., Dekkers, O. M., & Meijer, O. C. (2022) · BMJ Open · doi:10.1136/bmjopen-2022-062446 · Cited by 38
Insula shows abnormal task‐evoked and resting‐state activity in first‐episode drug‐naïve generalized anxiety disorder
Cui, H., Zhang, B., Li, W., Li, H., Pang, J., Hu, Q., Zhang, L., Tang, Y., Yang, Z., Wang, J., et al. (2020) · Depression and Anxiety · doi:10.1002/da.23009 · Cited by 38
An fMRI investigation of expectation violation in magic tricks
Danek, A. H., Ã–llinger, M., Fraps, T., Grothe, B., & Flanagin, V. L. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.00084 · Cited by 42
Mindfulness‐based cognitive therapy is associated with distinct resting‐state neural patterns in patients with generalized anxiety disorder
Zhao, X., Chen, Z., Kang, C., Liu, R., Bai, J., Cao, Y., Cheng, Y., Xu, X., & Zhang, Y. L. (2019) · Asia-Pacific Psychiatry · doi:10.1111/appy.12368 · Cited by 46
The relationship of perceptual discrimination to neural mechanisms of fear generalization
Tuominen, L. J., Boeke, E. A., DeCross, S. N., Wolthusen, R. P. F., Nasr, S., Milad, M. R., Vangel, M. G., Tootell, R. B. H., & Holt, D. J. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.12.034 · Cited by 34
Infant Formula Supplemented With Milk Fat Globule Membrane, Long-Chain Polyunsaturated Fatty Acids, and Synbiotics Is Associated With Neurocognitive Function and Brain Structure of Healthy Children Aged 6 Years: The COGNIS Study
Nieto-Ruíz, A., García-Santos, J. A., Verdejo‐Román, J., Diéguez, E., Sepúlveda-Valbuena, N., Herrmann, F., Cerdó, T., De-Castellar, R., Jiménez, J., García-Bermúdez, M., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.820224 · Cited by 36
Brain responses to disorder‐related visual threat in panic disorder
Feldker, K., Heitmann, C. Y., Neumeister, P., Bruchmann, M., Vibrans, L., Zwitserlood, P., & Straube, T. (2016) · Human Brain Mapping · doi:10.1002/hbm.23320 · Cited by 37
Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial)
Sposato, L. A., Cohen, G., Wardlaw, J. M., Sandercock, P. A., Lindley, R. I., Hachinski, V., von Kummer, R., von Heijne, A., Bradey, N., Peeters, A. P., et al. (2016) · Stroke · doi:10.1161/strokeaha.116.014928 · Cited by 35
Noninvasive Cervical Vagal Nerve Stimulation Alters Brain Activity During Traumatic Stress in Individuals With Posttraumatic Stress Disorder
Wittbrodt, M. T., Gurel, N. Z., Nye, J. A., Shandhi, M. M. H., Gazi, A. H., Shah, A. J., Pearce, B. D., Murrah, N. V., Ko, Y., Shallenberger, L. H., et al. (2021) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000987 · Cited by 34
Psychophysiological arousal and auditory sensitivity in a cross-clinical sample of autistic and non-autistic anxious adults
Top Jr., D. N., Luke, S. G., Stephenson, K. G., & South, M. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00783 · Cited by 36
“Eﬀective sensory processing is a critical evolutionary component for managing stress and danger [see (21–23)] and there are demonstrated links between sensory sensitivity and aﬀective disorders, including anxiety, outside of autism (24–27).”
Background
Thalamocortical connectivity and its relationship with symptoms and cognition across the psychosis continuum
Ramsay, I. S., Mueller, B. A., Ma, Y., Shen, C., & Sponheim, S. R. (2022) · Psychological Medicine · doi:10.1017/s0033291722002793 · Cited by 34
Brain Mapping-Based Model of Δ9-Tetrahydrocannabinol Effects on Connectivity in the Pain Matrix
Walter, C., Oertel, B. G., Felden, L., Kell, C. A., Nöth, U., Vermehren, J., Kaiser, J., Deichmann, R., & Lötsch, J. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.336 · Cited by 34
Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats
Bai, Y., Ma, L., Chen, Y., Ren, D., Chen, Y.-B., Li, Y.-Q., Sun, H., Qiu, X.-T., Zhang, M., Zhang, M.-M., et al. (2019) · Molecular Brain · doi:10.1186/s13041-019-0497-5 · Cited by 35
Aggression subtypes relate to distinct resting state functional connectivity in children and adolescents with disruptive behavior
Werhahn, J. E., Mohl, S., Willinger, D., Smigielski, L., Roth, A. C., Hofstetter, C., Stämpfli, P., Naaijen, J., Mulder, L. M., Glennon, J. C., et al. (2020) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-020-01601-9 · Cited by 36
Aberrant baseline brain activity in psychogenic erectile dysfunction patients: a resting state fMRI study
Jin, C., Guan, M., Dong, M., Wu, J., He, Z., Chen, X., Shi, D., Ren, J., Shi, G., & Zhang, X. (2017) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9805-9 · Cited by 33
Influence of Strategic Cortical Infarctions on Pupillary Function
Peinkhofer, C., Martens, P. C., Grand, J., Truelsen, T. C., Knudsen, G. M., Kjærgaard, J., & Kondziella, D. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00916 · Cited by 33
Empathy for Pain: Insula Inactivation and Systemic Treatment With Midazolam Reverses the Hyperalgesia Induced by Cohabitation With a Pair in Chronic Pain Condition
Zaniboni, C. R., Pelarin, V., Baptista‐de‐Souza, D., & Canto‐de‐Souza, A. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00278 · Cited by 32
Aberrations of anterior insular cortex functional connectivity in nontreatment-seeking alcoholics
Halcomb, M., Chumin, E. J., Goñi, J., Džemidžić, M., & Yoder, K. K. (2019) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2018.12.016 · Cited by 33
Autobiographical memories, identity disturbance and brain functioning in patients with borderline personality disorder: An fMRI study
Bozzatello, P., Morese, R., Valentini, M., Rocca, P., Bosco, F., & Bellino, S. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e01323 · Cited by 31
Directed threat imagery in generalized anxiety disorder
Buff, C., Schmidt, C. C., Brinkmann, L., Gathmann, B., Tupak, S. V., & Straube, T. (2017) · Psychological Medicine · doi:10.1017/s0033291717001957 · Cited by 32

Authors: Gasquoine, P. G.
Affiliations: The University of Texas System (US)
Corresponding author: Gasquoine, Philip Gerard
ORCID: Gasquoine, Philip Gerard
Venue: Neuropsychology Review
Publisher: Springer Science and Business Media LLC
Published: 2014-01-18
Volume: 24
Issue: 2
Pages: 77-87
ISSN: 1040-7308 (ISSN-L)
1573-6660
DOI: 10.1007/s11065-014-9246-9
OpenAlex: W1989986125
Cited by: 400
References: 136
Citations by year: 2026: 18 · 2025: 37 · 2024: 52 · 2023: 31 · 2022: 40 · 2021: 39 · 2020: 66 · 2019: 32 · 2018: 23 · 2017: 26 · 2016: 18 · 2015: 15 · 2014: 3
FWCI: 2.85
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Neuropsychology Review (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
Keywords: insula, interoception, emotions, James-Lange theory, autonomic nervous system, schizophrenia, eating disorders, mood and anxiety disorders, autism spectrum disorder, addiction, chronic pain, aphasia, language processing, anterior cingulate cortex, salience, consciousness, cognitive challenge
MeSH terms: Animals, Autonomic Nervous System, Brain Mapping, Cerebral Cortex, Cognition, Emotions, Humans

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Contributions of the Insula to Cognition and Emotion

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks