Cited by 187Health Systems, Economic Evaluations, Quality of LifeChildhood Cancer Survivors' Quality of LifeHealth Education and Validation

Reliability and validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) in a general population and respiratory disease sample

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Raat, Hein, Landgraf, Jeanne M., Oostenbrink, Rianne, Moll, Henriëtte A., Essink-Bot, Marie-Louise·2007·Quality of Life Research

Abstract

OBJECTIVE: To evaluate feasibility, internal consistency, test-retest reliability, and concurrent and discriminative validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) for parents of pre-school children with 12 scales (103-items) covering physical and psychosocial domains and impact of child health on parents, in comparison with the TNO-AZL Pre-school Children Quality of Life Questionnaire (TAPQOL). METHODS: Parents of children from a random general population sample (2 months-4 years old; n = 500) and of an outpatient clinic sample of children with respiratory disease (5 months-[Formula: see text] years old; n = 217) were mailed ITQOL and TAPQOL questionnaires; a retest was sent after two weeks. RESULTS: Feasibility: The response was >or=80% with few missing and non-unique ITQOL-answers (<2%) in both study populations. Some ITQOL-scales (3-4 scales) showed a ceiling effect (>25% at maximum score). Internal consistency: All Cronbach's alpha >0.70. Test-retest Intraclass Correlation Coefficients (ICCs) were moderate or adequate (>or=0.50; p < 0.01) for 10 ITQOL-scales. VALIDITY: ITQOL-scales, with a few exceptions, correlated better with predefined parallel TAPQOL scales than with non-parallel scales. Five to eight ITQOL-scales discriminated clearly between children with few and with many parent-reported chronic conditions, between children with and without doctor-diagnosed respiratory disease and with a low and a high parent-reported medical consumption (p < 0.05). CONCLUSIONS: This study supported the evidence that the ITQOL is a feasible instrument with adequate psychometric properties. The study provided reference ITQOL scores for gender/age subgroups. We recommend repeated evaluations of the ITQOL in varied populations, especially among very young children, including repeated assessments of test-retest characteristics and evaluations of responsiveness to change. We recommend developing and evaluating a shortened ITQOL version.

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Authors
Raat, H., Landgraf, J. M., Oostenbrink, R., Moll, H. A., & Essink-Bot, M.-L.
Affiliations
Erasmus MC (NL)
Corresponding author
Raat, Hein
Venue
Quality of Life Research
Published
2006-11-17
Volume
16
Issue
3
Pages
445-460
ISSN
  • 0962-9343 (ISSN-L)
  • 1573-2649
OpenAlex
W2053572857
Cited by
187
References
36
Citations by year
2026: 6 · 2025: 8 · 2024: 5 · 2023: 15 · 2022: 10 · 2021: 11 · 2020: 7 · 2019: 12 · 2018: 13 · 2017: 7 · 2016: 11 · 2015: 7 · 2014: 7 · 2013: 11 · 2012: 8
FWCI
15.94
Type
journal article
Language
en
Open access
Locations
  • Quality of Life Research (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
Funders
  • ZonMw (22000128)
  • Erasmus Universitair Medisch Centrum Rotterdam
Topics
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
  • Social Sciences › Education › Health Education and Validation
Keywords
quality of life, preschool children, respiratory diseases, psychometric properties, test-retest reliability, concurrent validity, discriminant validity, parent-reported quality of life, ceiling effect, health care utilization, psychosocial health
MeSH terms
Asthma, Child Welfare, Child, Preschool, Feasibility Studies, Female, Humans, Infant, Infant Welfare, Male, Netherlands, Psychometrics, Quality of Life, Surveys and Questionnaires, Respiratory Tract Diseases, Sickness Impact Profile, Proxy

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