Cited by 67Genetically Modified Organisms ResearchCarcinogens and Genotoxicity AssessmentAgricultural safety and regulations

Plurality of opinion, scientific discourse and pseudoscience: an in depth analysis of the Séralini et al. study claiming that Roundup™ Ready corn or the herbicide Roundup™ cause cancer in rats

Arjó, Gemma, Portero, Manuel, Piñol, Carme, Viñas, Juan, Matias-Guiu, Xavier, Capell, Teresa, Bartholomaeus, Andrew, Parrott, Wayne +1 more·2013·Transgenic Research

Abstract

A recent paper published in the journal Food and Chemical Toxicology presents the results of a long-term toxicity study related to a widely-used commercial herbicide (Roundup™) and a Roundup-tolerant genetically modified variety of maize, concluding that both the herbicide and the maize varieties are toxic. Here we discuss the many errors and inaccuracies in the published article resulting in highly misleading conclusions, whose publication in the scientific literature and in the wider media has caused damage to the credibility of science and researchers in the field. We and many others have criticized the study, and in particular the manner in which the experiments were planned, implemented, analyzed, interpreted and communicated. The study appeared to sweep aside all known benchmarks of scientific good practice and, more importantly, to ignore the minimal standards of scientific and ethical conduct in particular concerning the humane treatment of experimental animals.

Integrity signals

Registry

Crossref · 10.1007/s11248-013-9692-9

Cites

30 of 30 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The conclusions of the Séralini studies have been comprehensively rebutted in the literature and elsewhere by both academicians and regulatory authorities throughout the world.

    “The conclusions of the Séralini studies have been comprehensively rebutted in the literature and elsewhere by both academicians and regulatory authorities throughout the world (Arjo et al., 2013; FSANZ, 2011; Grunewald & Bury, 2012).”
  • Despite a wealth of studies and literature to the contrary, these isolated and poorly designed studies have resulted in the promulgation of new regulations, including a mandatory 90-d rodent subchronic toxicity feeding study for all new GE approvals in the EU, and have generated a great deal of media attention.

    “Despite a wealth of studies and literature to the contrary, these isolated and poorly designed studies have resulted in the promulgation of new regulations, including a mandatory 90-d rodent subchronic toxicity feeding study for all new GE approvals in the EU (Kuiper et al., 2013), and have generated a great deal of media attention (Arjó et al., 2013).”

Cites

1 retracted

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Arjó, G., Portero, M., Piñol, C., Viñas, J., Matias-Guiu, X., Capell, T., Bartholomaeus, A., Parrott, W., & Christou, P.
Affiliations
  • Universitat de Lleida (ES)
  • The University of Queensland (AU)
  • University of Georgia (US)
  • Institució Catalana de Recerca i Estudis Avançats (ES)
Corresponding author
Christou, Paul
Venue
Transgenic Research
Published
2013-02-22
Volume
22
Issue
2
Pages
255-267
ISSN
  • 0962-8819 (ISSN-L)
  • 1573-9368
OpenAlex
W2133860021
Cited by
67
References
30
Citations by year
2026: 1 · 2025: 1 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 5 · 2019: 4 · 2018: 5 · 2017: 7 · 2016: 3 · 2015: 11 · 2014: 12 · 2013: 8 · 2012: 1
FWCI
13.69
Type
journal article
Language
en
Open access
closed
Locations
  • Transgenic Research (publishedVersion)
  • PubMed (publishedVersion)
  • Repositori ObertUDL (University of Lleida) (publishedVersion)
  • University of Canberra Research Portal (submittedVersion)
  • RECERCAT (Consorci de Serveis Universitaris de Catalunya) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
Keywords
Roundup, glyphosate, transgenic maize, herbicide toxicity, pseudoscience, research misconduct, research ethics, animal welfare in research, scientific credibility, media coverage of science
MeSH terms
Glyphosate, Animals, Zea mays, Drug Tolerance, Glycine, Herbicides, Neoplasms, Science, Scientific Misconduct, Cultural Diversity, Food, Genetically Modified, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review