UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes

Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor

Pelegrı́n, P., & Surprenant, A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601378 · Cited by 1,428 · see citing works

International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy

Abbracchio, M. P., Burnstock, G., Boeynaems, J., Barnard, E. A., Boyer, J. L., Kennedy, C., Knight, G. E., Fumagalli, M., Gachet, C., Jacobson, K. A., et al. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.3 · Cited by 1,286 · see citing works

c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

Grigoriadis, A. E., Wang, Z., Cecchini, M. G., Hofstetter, W., Felix, R., Fleisch, H. A., & Wagner, E. F. (1994) · Science · doi:10.1126/science.7939685 · Cited by 1,260 · see citing works

Purine and pyrimidine receptors

Burnstock, G. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-6497-0 · Cited by 929 · see citing works

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction.

Tatsumi, S., Ishii, K., Amizuka, N., Li, M., Kobayashi, T., Kohno, K., Ito, M., Takeshita, S., & Ikeda, K. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.001 · Cited by 848 · see citing works

Pannexin membrane channels are mechanosensitive conduits for ATP

Bao, L., Locovei, S., & Dahl, G. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.07.009 · Cited by 804 · see citing works

Sensitivity of osteocytes to biomechanical stress in vitro

Klein‐Nulend, J., van der Plas, A., Semeins, C. M., Ajubi, N. E., Erangos, J. A., Nijweide, P. J., & Burger, E. H. (1995) · The FASEB Journal · doi:10.1096/fasebj.9.5.7896017 · Cited by 776 · see citing works

Functional Hemichannels in Astrocytes: A Novel Mechanism of Glutamate Release

Ye, Z., Wyeth, M. S., Tekkök, S. B., & Ransom, B. R. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-09-03588.2003 · Cited by 706 · see citing works

Establishment of an Osteocyte-like Cell Line, MLO-Y4

Kato, Y., Windle, J. J., Koop, B. A., Mundy, G. R., & Bonewald, L. F. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.12.2014 · Cited by 549 · see citing works

Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium

Locovei, S., Wang, J., & Dahl, G. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.12.004 · Cited by 520 · see citing works

Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

Aguirre, J. I., Plotkin, L. I., Stewart, S. A., Weinstein, R. S., Parfitt, A. M., Manolagas, S. C., & Bellido, T. (2006) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.060107 · Cited by 494 · see citing works

Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism

Malone, A. M. D., Anderson, C. T., Tummala, P., Kwon, R. Y., Johnston, T. R., Stearns, T., & Jacobs, C. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700636104 · Cited by 477 · see citing works

Probenecid, a gout remedy, inhibits pannexin 1 channels

Silverman, W. R., Locovei, S., & Dahl, G. (2008) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00227.2008 · Cited by 428 · see citing works

Oscillating fluid flow activation of gap junction hemichannels induces atp release from MLO‐Y4 osteocytes

Genetos, D. C., Kephart, C. J., Zhang, Y., Yellowley, C. E., & Donahue, H. J. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21021 · Cited by 328 · see citing works

Constitutive Release of ATP and Evidence for Major Contribution of Ecto-nucleotide Pyrophosphatase and Nucleoside Diphosphokinase to Extracellular Nucleotide Concentrations

Lazarowski, E. R., Boucher, R. C., & Harden, T. K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003255200 · Cited by 316 · see citing works

Direct Demonstration of Mechanically Induced Release of Cellular UTP and Its Implication for Uridine Nucleotide Receptor Activation

Lazarowski, E. R., Homolya, L., Boucher, R. C., & Harden, T. K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.39.24348 · Cited by 286 · see citing works

Fluid Shear-Induced ATP Secretion Mediates Prostaglandin Release in MC3T3-E1 Osteoblasts

Genetos, D. C., Geist, D. J., Liu, D., Donahue, H. J., & Duncan, R. L. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.041009 · Cited by 279 · see citing works

Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: Direct evidence for load-induced fluid flow

Price, C., Zhou, X., Li, W., & Wang, L. (2010) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.211 · Cited by 279 · see citing works

Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells

Ma, W., Hui, H., Pelegrı́n, P., & Surprenant, A. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.146365 · Cited by 273 · see citing works

The P2X7 Nucleotide Receptor Mediates Skeletal Mechanotransduction

Li, J., Liu, D., Ke, H. Z., Duncan, R. L., & Turner, C. H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506415200 · Cited by 269 · see citing works

Functional Gap Junctions Between Osteocytic and Osteoblastic Cells

Yellowley, C. E., Li, Z., Zhou, Z., Jacobs, C. R., & Donahue, H. J. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.2.209 · Cited by 259 · see citing works

ATP- and Gap Junction–dependent Intercellular Calcium Signaling in Osteoblastic Cells

Jørgensen, N. R., Geist, S. T., Civitelli, R., & Steinberg, T. H. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.2.497 · Cited by 248 · see citing works

Nucleotide receptor signaling in platelets

Kahner, B. N., Shankar, H. K., Murugappan, S., Prasad, G. L., & Kunapuli, S. P. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.02192.x · Cited by 219 · see citing works

Mechanically regulated expression of a neural glutamate transporter in bone: A role for excitatory amino acids as osteotropic agents?

Mason, D. J., Suva, L. J., Genever, P. G., Patton, A. J., Steuckle, S., Hillam, R. A., & Skerry, T. M. (1997) · Bone · doi:10.1016/s8756-3282(96)00386-9 · Cited by 213 · see citing works

Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity

Qin, Y., Kaplan, T., Saldanha, A., & Rubin, C. T. (2003) · Journal of Biomechanics · doi:10.1016/s0021-9290(03)00127-1 · Cited by 206 · see citing works

Visualization of ATP Release in Pancreatic Acini in Response to Cholinergic Stimulus

Sørensen, C. E., & Novak, I. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103313200 · Cited by 181 · see citing works

P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis

Panupinthu, N., Rogers, J. T., Zhao, L., Solano-Flores, L. P., Possmayer, F., Sims, S. M., & Dixon, S. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200708037 · Cited by 175 · see citing works

Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation

Wang, N., Bock, M. D., Antoons, G., Gadicherla, A. K., Bol, M., Decrock, E., Evans, W. H., Sipido, K. R., Bukauskas, F. F., & Leybaert, L. (2012) · Basic Research in Cardiology · doi:10.1007/s00395-012-0304-2 · Cited by 161 · see citing works

Quantitation of extracellular UTP using a sensitive enzymatic assay

Lazarowski, E. R., & Harden, T. K. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702654 · Cited by 152 · see citing works

P2X7 Receptor Channels Allow Direct Permeation of Nanometer-Sized Dyes

Browne, L. E., Compan, V., Bragg, L., & North, R. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2235-12.2013 · Cited by 151 · see citing works

Primary cilium‐dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells

Kwon, R. Y., Temiyasathit, S., Tummala, P., Quah, C. C., & Jacobs, C. R. (2010) · The FASEB Journal · doi:10.1096/fj.09-148007 · Cited by 144 · see citing works

Extracellular Nucleotides Block Bone Mineralization in Vitro: Evidence for Dual Inhibitory Mechanisms Involving Both P2Y2 Receptors and Pyrophosphate

Orriss, I. R., Utting, J. C., Brandao‐Burch, A., Colston, K. W., Grubb, B. R., Burnstock, G., & Arnett, T. R. (2007) · Endocrinology · doi:10.1210/en.2007-0066 · Cited by 144 · see citing works

Intercellular Calcium Signaling Occurs between Human Osteoblasts and Osteoclasts and Requires Activation of Osteoclast P2X7 Receptors

Jørgensen, N. R., Henriksen, Z., Sørensen, O., Eriksen, E. F., Civitelli, R., & Steinberg, T. H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m104608200 · Cited by 143 · see citing works

Osteocytic expression of mRNA for c-fos and IGF-I: an immediate early gene response to an osteogenic stimulus

Lean, J. M., Mackay, A. G., Chow, J. W., & Chambers, T. J. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.6.e937 · Cited by 139 · see citing works

Extracellular Nucleotides Act Through P2X7 Receptors to Activate NF-κB in Osteoclasts

Korčok, J., Raimundo, L., Ke, H. Z., Sims, S. M., & Dixon, S. J. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.040108 · Cited by 138 · see citing works

Calcium response in single osteocytes to locally applied mechanical stimulus: Differences in cell process and cell body

ADACHI, T., Aonuma, Y., TANAKA, M., Hojo, M., Takano‐Yamamoto, T., & Kamioka, H. (2009) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2009.04.034 · Cited by 134 · see citing works

Osteoblast responses to nucleotides increase during differentiation

Orriss, I. R., Knight, G. E., Ranasinghe, S., Burnstock, G., & Arnett, T. R. (2006) · Bone · doi:10.1016/j.bone.2006.02.063 · Cited by 127 · see citing works

ATP and UTP at low concentrations strongly inhibit bone formation by osteoblasts: A novel role for the P2Y2 receptor in bone remodeling

Hoebertz, A., Mahendran, S., Burnstock, G., & Arnett, T. R. (2002) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10236 · Cited by 112 · see citing works

Human Osteoblastic Cells Propagate Intercellular Calcium Signals by Two Different Mechanisms

Jørgensen, N. R., Henriksen, Z., Brot, C., Eriksen, E. F., Sørensen, O., Civitelli, R., & Steinberg, T. H. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.6.1024 · Cited by 108 · see citing works

Calcium response in osteocytic networks under steady and oscillatory fluid flow

Lu, X. L., Huo, B., Park, M., & Guo, X. E. (2012) · Bone · doi:10.1016/j.bone.2012.05.021 · Cited by 105 · see citing works

β1 Integrins Mediate Mechanosensitive Signaling Pathways in Osteocytes

Litzenberger, J. B., Kim, J., Tummala, P., & Jacobs, C. R. (2010) · Calcified Tissue International · doi:10.1007/s00223-010-9343-6 · Cited by 105 · see citing works

Extracellular ADP is a powerful osteolytic agent: evidence for signaling through the P2Y 1 receptor on bone cells

Hoebertz, A., Meghji, S., Burnstock, G., & Arnett, T. R. (2001) · The FASEB Journal · doi:10.1096/fj.00-0395com · Cited by 97 · see citing works

Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-κB ligand

Buckley, K. M., Hipskind, R. A., Gartland, A., Bowler, W. B., & Gallagher, J. A. (2002) · Bone · doi:10.1016/s8756-3282(02)00877-3 · Cited by 97 · see citing works

Neural regulation of bone and the skeletal effects of serotonin (5-hydroxytryptamine)

Warden, S. J., Bliziotes, M. M., Wiren, K. M., Eshleman, A. J., & Turner, C. H. (2005) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.06.005 · Cited by 76 · see citing works

αVβ3 Integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes

Miyauchi, A., Gotoh, M., Kamioka, H., Notoya, K., Sekiya, H., Takagi, Y., Yoshimoto, Y., Ishikawa, H., Chihara, K., Takano‐Yamamoto, T., et al. (2006) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-006-0716-x · Cited by 74 · see citing works

Clopidogrel (Plavix), a P2Y12 receptor antagonist, inhibits bone cell function in vitro and decreases trabecular bone in vivo

Syberg, S., Brandao‐Burch, A., Patel, J. J., Hajjawi, M. O. R., Arnett, T. R., Schwarz, P., Jørgensen, N. R., & Orriss, I. R. (2012) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1690 · Cited by 67 · see citing works

Osteocytes: central conductors of bone biology in normal and pathological conditions

Neve, A., Corrado, A., & Cantatore, F. P. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2011.02385.x · Cited by 62 · see citing works

ATP storage and uptake by isolated pancreatic zymogen granules

Haanes, K. A., & Novak, I. (2010) · Biochemical Journal · doi:10.1042/bj20091337 · Cited by 57 · see citing works

Primary Cultures of Chick Osteocytes Retain Functional Gap Junctions between Osteocytes and between Osteocytes and Osteoblasts

Kamioka, H., Ishihara, Y., Ris, H., Murshid, S. A., Sugawara, Y., Takano‐Yamamoto, T., & Lim, S. (2007) · Microscopy and Microanalysis · doi:10.1017/s143192760707016x · Cited by 53 · see citing works

ATP-consuming and ATP-generating Enzymes Secreted by Pancreas

Yegutkin, G. G., Samburski, S. S., Jalkanen, S., & Novak, I. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602480200 · Cited by 50 · see citing works

Purinergic signalling in osteoblasts

Gartland, A. (2011) · Frontiers in bioscience · doi:10.2741/3912 · Cited by 38 · see citing works

P2 receptor expression, signaling and function in osteoclasts

Juan, P. R. (2011) · Frontiers in Bioscience-Scholar · doi:10.2741/214 · Cited by 25 · see citing works

Expression of multiple P2 receptor subtypes by osteoblasts and osteoclasts

Orriss, I. R., Burnstock, G., & Arnett, T. R. (2009) · Bone · doi:10.1016/j.bone.2009.03.559 · Cited by 4 · see citing works

Effects of acute hypoxia on osteoclast activity: A balance between enhanced resorption and increased apoptosis

Knowles, H. J., & Athanasou, N. A. (2008) · Calcified Tissue International · Cited by 4 · see citing works

Nucleotide and mechanically induced ATP release pathways in osteocytes

Kringelbach, T. M., Novak, I., Schwarz, P., & Jørgensen, N. R. (2013) · Bone Abstracts · doi:10.1530/boneabs.1.pp237 · Cited by 2 · see citing works

Bone remodeling: an operational process ensuring survival and bone mechanical competence

Bolamperti, S., Villa, I., & Rubinacci, A. (2022) · Bone Research · doi:10.1038/s41413-022-00219-8 · Cited by 482 · see citing works

Pyrophosphate: a key inhibitor of mineralisation

Orriss, I. R., Arnett, T. R., & Russell, R. G. G. (2016) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2016.03.003 · Cited by 181 · see citing works

Silicon Nitride: A Bioceramic with a Gift

Pezzotti, G. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b07997 · Cited by 106 · see citing works

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1 mice

Hajjawi, M. O. R., MacRae, V. E., Huesa, C., BOYDE, A., Millán, J. L., Arnett, T. R., & Orriss, I. R. (2014) · Bone · doi:10.1016/j.bone.2014.09.016 · Cited by 68 · see citing works

Extracellular pyrophosphate: The body's “water softener”

Orriss, I. R. (2020) · Bone · doi:10.1016/j.bone.2020.115243 · Cited by 59 · see citing works

Mesenchymal Stem Cells Ageing: Targeting the “Purinome” to Promote Osteogenic Differentiation and Bone Repair

Noronha‐Matos, J. B., & Correia‐de‐Sá, P. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25303 · Cited by 58 · see citing works

Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair

Mikolajewicz, N., Zimmermann, E. A., Willie, B. M., & Komarova, S. V. (2018) · eLife · doi:10.7554/elife.37812 · Cited by 50 · see citing works

ATP release, generation and hydrolysis in exocrine pancreatic duct cells

Kowal, J. M., Yegutkin, G. G., & Novak, I. (2015) · Purinergic Signalling · doi:10.1007/s11302-015-9472-5 · Cited by 42 · see citing works

Purinergic Cooperation Between P2Y2 and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

Thorstenberg, M. L., Ferreira, M. V. R., Amorim, N., Canetti, C. D. A., Morrone, F. B., Filho, J. C. F. A., & Coutinho‐Silva, R. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01531 · Cited by 36 · see citing works

Adenosine Triphosphate stimulates differentiation and mineralization in human osteoblast‐like Saos‐2 cells

Cutarelli, A., Marini, M., Tancredi, V., D’Arcangelo, G., Murdocca, M., Frank, C., & Tarantino, U. (2016) · Development Growth & Differentiation · doi:10.1111/dgd.12288 · Cited by 34 · see citing works

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release

Orriss, I. R., Guneri, D., Hajjawi, M. O. R., Shaw, K., Patel, J. J., & Arnett, T. R. (2017) · Journal of Endocrinology · doi:10.1530/joe-17-0042 · Cited by 33 · see citing works

Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts

Certal, M., Vinhas, A., Pinheiro, A. R., Ferreirinha, F., Barros‐Barbosa, A., da Silva, I. C. B., Costa, M. A., & Correia‐de‐Sá, P. (2015) · Cell Calcium · doi:10.1016/j.ceca.2015.08.004 · Cited by 31 · see citing works

The purinergic P2X7 ion channel receptor — a ‘repair’ receptor in bone

Jørgensen, N. R. (2018) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.03.016 · Cited by 31 · see citing works

TRPV4 calcium influx controls sclerostin protein loss independent of purinergic calcium oscillations

Williams, K. M., Leser, J. M., Gould, N. R., Joca, H. C., Lyons, J. S., Khairallah, R. J., Ward, C. W., & Stains, J. P. (2020) · Bone · doi:10.1016/j.bone.2020.115356 · Cited by 31 · see citing works

From death to birth: how osteocyte death promotes osteoclast formation

Zhao, W., Qian, J., Li, J., Su, T., Deng, X., Fu, Y., Liang, X., & Cui, H. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1551542 · Cited by 26 · see citing works

The role of purinergic signalling in the musculoskeletal system

Orriss, I. R. (2015) · Autonomic Neuroscience · doi:10.1016/j.autneu.2015.04.013 · Cited by 25 · see citing works

Rescuing SERCA2 pump deficiency improves bone mechano-responsiveness in type 2 diabetes by shaping osteocyte calcium dynamics

Shao, X., Tian, Y., Liu, J., Yan, Z., Ding, Y., Hao, X., Wang, D., Shen, L., Luo, E., Guo, X.-D. E., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45023-6 · Cited by 23 · see citing works

Silicon nitride as a biomaterial

Pezzotti, G. (2023) · Journal of the Ceramic Society of Japan · doi:10.2109/jcersj2.23057 · Cited by 23 · see citing works

Muscle strength, power and cardiorespiratory fitness are associated with bone mineral density in men aged 31–60 years

Schwarz, P., Jørgensen, N. R., Nielsen, B. R., Laursen, A. S. D., Linneberg, A. R., & Aadahl, M. (2014) · Scandinavian Journal of Public Health · doi:10.1177/1403494814552119 · Cited by 20 · see citing works

Signaling of the Purinergic System in the Joint

Corciulo, C., & Cronstein, B. N. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01591 · Cited by 20 · see citing works

Extracellular purines and bone homeostasis

Agrawal, A., & Jørgensen, N. R. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114425 · Cited by 18 · see citing works

Extracellular ATP and its derivatives provide spatiotemporal guidance for bone adaptation to wide spectrum of physical forces

Dsouza, C., Moussa, M., Mikolajewicz, N., & Komarova, S. V. (2022) · Bone Reports · doi:10.1016/j.bonr.2022.101608 · Cited by 15 · see citing works

Calcium response in bone cells at different osteogenic stages under unidirectional or oscillatory flow

Wang, S., Li, S., Hu, M., & Huo, B. (2019) · Biomicrofluidics · doi:10.1063/1.5128696 · Cited by 15 · see citing works

P2Y Receptors in Bone - Anabolic, Catabolic, or Both?

Zhou, Y., Carrera, H. M. A., & Wang, N. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.818499 · Cited by 10 · see citing works

Targeting P2 receptors—current progress in treating musculoskeletal diseases

Wang, N., & Gartland, A. (2014) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2014.05.004 · Cited by 10 · see citing works

A multiscale fluidic device for the study of dendrite-mediated cell to cell communication

McCutcheon, S., Majeska, R. J., Schaffler, M. B., & Vázquez, M. (2017) · Biomedical Microdevices · doi:10.1007/s10544-017-0212-1 · Cited by 9 · see citing works

Purinergic signaling through the P2Y2 receptor regulates osteocytes’ mechanosensitivity

Chougule, A., Zhang, C., Vinokurov, N., Mendez, D., Vojtisek, E., Shi, C., Zhang, J., & Gardinier, J. D. (2024) · The Journal of Cell Biology · doi:10.1083/jcb.202403005 · Cited by 6 · see citing works

Modulation of osteoblast differentiation and function by the P2X4 receptor

Orriss, I. R., Davies, B. K., Bourne, L. E., & Arnett, T. R. (2022) · Purinergic Signalling · doi:10.1007/s11302-022-09887-x · Cited by 5 · see citing works

Pathological calcification in canine tendon-derived cells is modulated by extracellular ATP

Zamboulis, D. E., Marr, N., Moustafa, A., Meeson, R., Orriss, I. R., & Thorpe, C. T. (2024) · Veterinary Research Communications · doi:10.1007/s11259-024-10331-1 · Cited by 2 · see citing works

Physical fitness components are bone mineral density predictors in adulthood: cross-sectional study

da Costa, J. C., de Freitas, M. C. M., Barbosa, C. C. L., Guzman, A., de Campos, L. F. C. C., Gómez‐Campos, R., Cossio‐Bolaños, M., & Ronque, Ê. R. V. (2024) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-024-07801-7 · Cited by 3 · see citing works

Absence of P2Y2 Receptor Does Not Prevent Bone Destruction in a Murine Model of Muscle Paralysis-Induced Bone Loss

Agrawal, A., Ellegaard, M., Haanes, K. A., Wang, N., Gartland, A., Ding, M. L., Prætorius, H. A., & Jørgensen, N. R. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.850525 · Cited by 2 · see citing works

The Antipathogenic Properties of Silicon Nitride

Pezzotti, G., & McEntire, B. J. (2024) · Springer eBooks · doi:10.1007/978-3-031-67047-3_6

P2Y Receptor Endocytosis and Signaling

Krittika, B., Mohima, M., & Sahu, B. S. (2025) · The Receptors · doi:10.1007/978-3-031-81991-9_13

Extracellular ATP and the bone

Gartland, A., Shah, K. M., & Tattersall, L. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-30250-3.00036-9

Fine-tuned ATP signals are acute mediators in osteocyte mechanotransduction

Kringelbach, T. M., Aslan, D., Novak, I., Ellegaard, M., Syberg, S., Andersen, C. K. B., Kristiansen, K. A., Vang, O., Schwarz, P., & Jørgensen, N. R. (2015) · Cellular Signalling · doi:10.1016/j.cellsig.2015.08.016 · Cited by 49 · see citing works

The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading

Wang, N., Rumney, R. M. H., Yang, L., Robaye, B., Boeynaems, J. M., Skerry, T. M., & Gartland, A. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1877 · Cited by 34 · see citing works

UTP and mechanical stimulation induce ATP release from osteocytes.

Kringelbach, T. M., Novak, I., Bonewald, L. F., Vang, O., Schwarz, P., & Jørgensen, N. R. (2012) · Bone · doi:10.1016/j.bone.2012.02.285 · Cited by 2 · see citing works

Purinergic mechanotransduction in bone

Mikolajewicz, N. (2019) · doi:10.13140/rg.2.2.15018.57289

Purinergic signalling in bone cells

Hoebertz, A. (2001) · OpenGrey (Institut de l'Information Scientifique et Technique)