Cited by 148Emotion and Mood RecognitionHeart Rate Variability and Autonomic ControlNon-Invasive Vital Sign Monitoring

Measuring acute stress response through physiological signals: towards a quantitative assessment of stress

Open access
Arza, Adriana, Garzón-Rey, Jorge Mario, Lázaro, Jesús, Gil, Eduardo, Lopez-Anton, Raul, de la Camara, Conchita, Laguna, Pablo, Bailon, Raquel +1 more·2019·Medical & Biological Engineering & Computing

Abstract

Social and medical problems associated with stress are increasing globally and seriously affect mental health and well-being. However, an effective stress-level monitoring method is still not available. This paper presents a quantitative method for monitoring acute stress levels in healthy young people using biomarkers from physiological signals that can be unobtrusively monitored. Two states were induced to 40 volunteers, a basal state generated with a relaxation task and an acute stress state generated by applying a standard stress test that includes five different tasks. Standard psychological questionnaires and biochemical markers were utilized as ground truth of stress levels. A multivariable approach to comprehensively measure the physiological stress response is proposed using stress biomarkers derived from skin temperature, heart rate, and pulse wave signals. Acute physiological stress levels (total-range 0-100 au) were continuously estimated every 1 min showing medians of 29.06 au in the relaxation tasks, while rising from 34.58 to 47.55 au in the stress tasks. Moreover, using the proposed method, five statistically different stress levels induced by the performed tasks were also measured. Results obtained show that, in these experimental conditions, stress can be monitored from unobtrusive biomarkers. Thus, a more general stress monitoring method could be derived based on this approach. Graphical abstract Stress measurements of different healthy young people throughout a Stress Session that includes a pre-relax stage (BL s), memory test (ST and MT), stress anticipation time (SA), video display (VD) and arithmetic task.

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Crossref · 10.1007/s11517-018-1879-z

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Authors
Arza, A., Garzón-Rey, J. M., Lázaro, J., Gil, E., Lopez-Anton, R., de la Camara, C., Laguna, P., Bailon, R., & Aguiló, J.
Affiliations
  • Universitat Autònoma de Barcelona (ES)
  • University of Connecticut (US)
  • Universidad de Zaragoza (ES)
Corresponding author
  • Arza, Adriana
  • Aguiló, Jordi
Venue
Medical & Biological Engineering & Computing
Published
2018-08-09
Volume
57
Issue
1
Pages
271-287
ISSN
  • 0140-0118 (ISSN-L)
  • 1741-0444
OpenAlex
W2886983335
Cited by
148
References
59
Citations by year
2026: 11 · 2025: 23 · 2024: 30 · 2023: 26 · 2022: 20 · 2021: 22 · 2020: 9 · 2019: 7
FWCI
12.44
Type
journal article
Language
en
Open access
Licence
Locations
  • Medical & Biological Engineering & Computing (publishedVersion)
  • PubMed (publishedVersion)
  • Zaguan (University of Zaragoza Repository) (acceptedVersion, cc-by-nc-nd)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by-nc-nd)
  • Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
Funders
  • Consejo Superior de Investigaciones Científicas (FIS-PI12/00514, TIN2014-53567-R)
  • Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Emotion and Mood Recognition
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
Keywords
acute stress response, stress monitoring, physiological biomarkers, non-intrusive monitoring, skin temperature, heart rate, pulse wave, stress testing, young adults, mental health
MeSH terms
Electrocardiography, Humans, Monitoring, Physiologic, Signal Processing, Computer-Assisted, Stress, Psychological, Biomarkers, Photoplethysmography

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