Magnetic iron oxide nanoparticles: synthesis and surface functionalization strategies
Open accessAbstract
Surface functionalized magnetic iron oxide nanoparticles (NPs) are a kind of novel functional materials, which have been widely used in the biotechnology and catalysis. This review focuses on the recent development and various strategies in preparation, structure, and magnetic properties of naked and surface functionalized iron oxide NPs and their corresponding application briefly. In order to implement the practical application, the particles must have combined properties of high magnetic saturation, stability, biocompatibility, and interactive functions at the surface. Moreover, the surface of iron oxide NPs could be modified by organic materials or inorganic materials, such as polymers, biomolecules, silica, metals, etc. The problems and major challenges, along with the directions for the synthesis and surface functionalization of iron oxide NPs, are considered. Finally, some future trends and prospective in these research areas are also discussed.
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Under hydrothermal conditions, it is difficult to control the final size of particles and most of the time polydisperse samples are obtained.
“However, it is difficult to control the final size of particles and most of the times polydisperse samples are obtained under hydrothermal conditions [3, 28, 46].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [46]
Amorphous SPION obtained from sonochemical synthesis need further heat-treatment after synthesis.
“Thus, the obtained amorphous SPION need to be further processed by heat-treatment after they have been synthesized [3, 28, 46–48].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [46]
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- Authors
- Wu, W., He, Q., & Jiang, C.
- Affiliations
- Wuhan University (CN)
- Hunan University of Technology (CN)
- Corresponding author
- Jiang, Changzhong
- Venue
- Nanoscale Research Letters
- Published
- 2008-10-02
- Volume
- 3
- Issue
- 11
- Pages
- 397-415
- ISSN
- 1556-276X (ISSN-L)
- PMC
- PMC3244954
- OpenAlex
- W2157255155
- Cited by
- 2,300
- References
- 151
- Citations by year
- 2026: 90 · 2025: 107 · 2024: 138 · 2023: 162 · 2022: 194 · 2021: 195 · 2020: 177 · 2019: 184 · 2018: 214 · 2017: 171 · 2016: 183 · 2015: 126 · 2014: 122 · 2013: 110 · 2012: 44
- FWCI
- 13.95
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Nanoscale Research Letters (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Magnetic Properties and Synthesis of Ferrites
- Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Iron oxide chemistry and applications
- Keywords
- magnetic iron oxide nanoparticles, surface functionalization, nanoparticle synthesis, magnetic saturation, biocompatibility, polymer coatings, silica coating, metal coatings, biomolecule functionalization, magnetic properties, nanoparticle stability, biomedical applications, catalysis
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