Variability in recovery from aphasia
Abstract
Clinicians have long recognized the enormous variability of recovery among patients with aphasia. Accordingly, the identification of specific factors most important in determining the extent of recovery has been the subject of many investigations. Yet, the reasons for two patients of the same age, nearly identical clinical presentations, and similar MRI findings having completely dissimilar recoveries are still unknown. It remains difficult for a clinician to make a valid prognosis of language recovery in an individual patient. This article provides a review of aphasia-recovery research and a framework for approaching the variability of recovery in clinical practice.
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Education influences inter-individual variability in treated language improvement in post-stroke aphasia.
“It is well established that inter-individual variability in TLI in post-stroke aphasia is influenced by an array of factors, including, but not limited to, age12–15, education16–19, aphasia severity11,14,15,20,21, baseline cognitive abilities13,22,23, and, specific to bPWA, bilingual language experience and language of treatment (e.g., whether therapy is delivered in L1 or L2)24,25.”
From Machine Learning Predictions of Recovery in Bilingual Poststroke Aphasia: Aligning Insights With Clinical Evidence (2025) · cites this paper as [16]
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- Authors
- Lazar, R. M., & Antoniello, D.
- Affiliations
- Columbia University Irving Medical Center (US)
- Corresponding author
- Lazar, Ronald M.
- Venue
- Current Neurology and Neuroscience Reports
- Published
- 2008-11
- Volume
- 8
- Issue
- 6
- Pages
- 497-502
- ISSN
- 1528-4042 (ISSN-L)
- 1534-6293
- OpenAlex
- W2083676933
- Cited by
- 132
- References
- 36
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 7 · 2023: 18 · 2022: 12 · 2021: 10 · 2020: 10 · 2019: 7 · 2018: 7 · 2017: 6 · 2016: 9 · 2015: 8 · 2014: 3 · 2013: 8 · 2012: 2
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Neurology and Neuroscience Reports (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD043249)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Keywords
- aphasia, language recovery, prognosis, predictors of recovery, stroke, brain MRI findings
- MeSH terms
- Stroke Rehabilitation, Aphasia, Female, Humans, Functional Laterality, Male, Neuropsychological Tests, Recovery of Function, Stroke
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