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Borderline personality disorder and childhood trauma: Evidence for a causal relationship
Abstract
The debate over whether childhood trauma is a causative factor in the development of borderline personality disorder continues in the literature despite decades of research. This review examines this body of literature published from 1995 through 2007 to assess the strength of evidence for such a causal relationship. A unique conceptual approach was used, as we considered the literature in the context of Hill's classic criteria for demonstrating causation. Results of this review suggest that evidence supports the causal relationship, particularly if the relationship is considered as part of a multifactorial etiologic model. Directions for future research and clinical implications are discussed.
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“Furthermore, the early rejection experiences proposed to underlie RS may overlap within the invalidating environments frequently observed in the childhood of people with BPD (Ball & Links, 2009;Crowell, Beauchaine, & Linehan, 2009).”
From The link between rejection sensitivity and borderline personality disorder: A systematic review and meta-analysis (2019) · cites this paper as Ball & Links, 2009
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“High risk behaviors in the context of BPD can manifest in various forms, including suicidal or addictive behaviors, eating disorders, and promiscuous sexual behavior, which are more common in BPD (16).”
BackgroundApplication of EMDR Therapy for Borderline Personality Disorder
Mosquera, D., Leeds, A. M., & González, A. (2014) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.8.2.74 · Cited by 22
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BackgroundResultAnimal Models of Early-Life Adversity
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“…found between sexual abuse and the lifestyle features of psychopathy in female offenders is related to impulsivity, since childhood sexual abuse has in many studies been linked to borderline personality disorder and impulsivity (Ball & Links, 2009; Paris, 2005; Widom, Czaja, & Paris, 2009).”
BackgroundA Non-linear Predictive Model of Borderline Personality Disorder Based on Multilayer Perceptron
Maldonato, M. N., Sperandeo, R., Moretto, E., & Dell’Orco, S. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.00447 · Cited by 20
“In terms of etiopathogenesis, substantial epidemiological (Ball and Links, 2009) evidence shows that subjects with BPD have traumatic events in their preceding anamnestic history.”
BackgroundSpecific type of childhood trauma and borderline personality disorder in Chinese patients
Wu, Y., Zheng, Y., Wang, J., & Zhang, T. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.936739 · Cited by 19
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“In regards to BPD, a causal relationship has been proposed [23].”
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Dimaro, L. V., Roberts, N. A., Moghaddam, N. G., Dawson, D. L., Brown, I., & Reuber, M. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.03.032 · Cited by 23
“Notably, discrepancies in either direction are thought to be maladaptive and have been found to correlate with psychological distress in depression [22] and borderline personality disorder [23], both of which are associated with childhood trauma [24] and [25] and PNESs [3] and [4].”
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“Epigenetic reprogramming and valproate Evidence supports the causal relationship between early life stressors, such as childhood maltreatment, and the development of BPD, with up to 70% of patients reporting major childhood trauma [Ball and Links, 2009].”
BackgroundSchiavone, F. L., McKinnon, M. C., & Lanius, R. A. (2018) · Chronic Stress · doi:10.1177/2470547018797046 · Cited by 20
“BPD is associated with traumatic life events (particularly childhood abuse) with some authors proposing that childhood trauma serves as part of a multifactorial etiology for the disorder.(36,63) Among individuals with BPD, estimates of the prevalence of childhood maltreatment typically range from 76% to 90% for childh…”
BackgroundPeters, J. R., & Eisenlohr-Moul, T. A. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1096-y · Cited by 16
Persönlichkeitsentwicklung im Kindes- und Jugendalter
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Stress Neurobiology and Developmental Psychopathology
Jacoby, N., Overfeld, J., Binder, E. B., & Heim, C. M. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy221 · Cited by 16
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“The test for HPA functioning, combining dexamethasone with Corticotropin Releasing Hormone [CRH] (DEX-CRH), has been found to be sensitive to trauma history, a major etiological factor in BPD [9, 19, 40, 41].”
MethodLeptin Levels in Acute and Recovered Eating Disorders: An Arm‐Based Network Meta‐Analysis
Cassioli, E., Angeletti, L. L., Rossi, E., Selvi, G., Riccardi, E., Siviglia, S., Buonanno, R., Ricca, V., & Castellini, G. (2024) · European Eating Disorders Review · doi:10.1002/erv.3163 · Cited by 15
The Self–Other Distinction in Psychopathology: Recent Developments from a Mentalizing Perspective
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“…478–486, 2015 Copyright Taylor & Francis Group, LLC ISSN: 0022-3891 print / 1532-7752 online DOI: 10.1080/00223891.2015.1051226 emotional abuse (Ball & Links, 2009; Beauchaine, Klein, Crowell, Derbidge, & Gatzke-Kopp, 2009; Bornovalova, Gratz, Delany-Brumsey, Paulson, & Lejuez, 2006; Carlson,…”
BackgroundInfluentialCommon elements for the psychotherapeutic management of patients with Self Injurious Behavior
Schiavone, F. L., & Links, P. S. (2012) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2012.09.012 · Cited by 15
Self-citationImpact of Diagnosis Disclosure on Adolescents with Borderline Personality Disorder.
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Rosenbaum, D., Int-Veen, I., Laicher, H., Woloszyn, L., Wiegand, A., Ladegast, S., Eßer, U., Kroczek, A., Sippel, D., Menkor, S., et al. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100640 · Cited by 14
“…also other mental disorders such as PTSD (Zaidi and Foy, 1994), psychotic disorders (Chaiyachati and Gur, 2021), Borderline Personality Disorder (Ball and Links, 2009; Cattane et al., 2017) and other anxiety disorders (Cougle et al., 2010; Safren et al., 2002), and those disorders have been…”
BackgroundLawrence, D., Bagshaw, R., Stubbings, D. R., & Watt, A. A. (2024) · Issues in Mental Health Nursing · doi:10.1080/01612840.2024.2369594 · Cited by 16
“For example, higher levels of experienced trauma increase risk for psychosis and borderline personality disorder (Ball & Links, 2009; Bentall et al., 2012).”
Trauma-related altered states of consciousness in women with BPD with or without co-occurring PTSD
Frewen, P., Kleindienst, N., Lanius, R. A., & Schmahl, C. G. (2014) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v5.24863 · Cited by 16
“For example, the prevalence of childhood sexual abuse in BPD patients ranges between 52 and 71% (Ball & Links, 2009; Zanarini, 1997), and Cutajar et al. (2010) found that the risk for BPD was increased about sixfold in persons with a history of childhood sexual abuse.”
BackgroundMishara, B. L., & Chagnon, F. (2011) · Wiley eBooks · doi:10.1002/9781119998556.ch35 · Cited by 13
Powell, T., Parker, J., Kitson, H., & Rogalewski, M. (2024) · Autism in Adulthood · doi:10.1089/aut.2023.0031 · Cited by 10
“Such factors may make individuals more vulnerable to BPD or cPTSD 29,30 or alternatively being mislabeled with BPD. 7, 7,11,26,28 Self-harm in autism is strongly associated with sensory and social overload, change and uncertainty.”
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Cognitive behaviour therapy for low self-esteem in a person with a learning disability: a case study
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Countering essentialism in psychiatric narratives
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“…childhood abuse or neglect and exhibit symptoms of borderline personality disorder such as emotional instability, impulsivity, and fear of abandonment, the context of the traumatic experience and personal history would be essential for accurate understanding and treatment (Ball & Links, 2009).”
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“Moreover, traumas are associated not only with depression and bipolar disorder but also with other psy-chopathologies such as addiction (S. H. Stewart, 1996) and borderline personality (Ball & Links, 2009).”
Components of event-related potentials and borderline personality disorder: a meta-analysis
Salas, F., Nvo-Fernández, M., Bianchi, M. L., Avello-Sáez, D., Sepúlveda-Páez, G. L., García, M. V., & Villacura-Herrera, C. (2024) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2297641 · Cited by 11
“…systems, however, they could be produced by the main factor at the basis of BPD development: exposure to traumatic events occurring mainly during childhood (Amad et al., 2019; Ball & Links, 2009; Crowell et al., 2009; Jaworska-Andryszewska & Rybakowski, 2022; Stepp et al., 2016; Yuan et al., 2023).”
BackgroundSusceptibility to Distraction by Social Cues in Borderline Personality Disorder
Krause-Utz, A., Elzinga, B. M., Oei, N. Y. L., Spinhoven, P., Bohus, M., & Schmahl, C. G. (2013) · Psychopathology · doi:10.1159/000351740 · Cited by 11
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“Stopping peer victimisation early can reduce the costs inflicted by BPD on people with this diagnosis, carers and health-care systems (Ball and Link 2009; Lester and Cross 2014; Scott et al. 2001).”
BackgroundGeneralizable Links Between Borderline Personality Traits and Functional Connectivity
Shafiei, G., Keller, A. S., Bertolero, M. A., Shanmugan, S., Bassett, D. S., Chen, A. A., Covitz, S. C., Houghton, A., Luo, A. C., Mehta, K. P., et al. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.02.1016 · Cited by 13
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“Previous research indicated a significant correlation between childhood trauma and BPD [17, 20], and childhood trauma is recognized as an important cause of BPD [21].”
BackgroundViewing psychopathology through a trauma lens
Bransford, C. L., & Blizard, R. A. (2016) · Social Work in Mental Health · doi:10.1080/15332985.2016.1173161 · Cited by 10
“There is also no acknowledgment inDSM-5 about the significance of trauma in the histories of personswithBPD, despite an extensive literature demonstrating the history of chronic trauma, especially relational trauma, in the majority of persons diagnosed with BPD (Freyd, DePrince, & Zurbriggen, 2001; Kaehler & Freyd, 20…”
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Erazo, M. B., Krygsman, A., & Vaillancourt, T. (2022) · International Journal of Bullying Prevention · doi:10.1007/s42380-022-00122-0 · Cited by 10
Related Personality Disorders Located within an Elaborated Externalizing Psychopathology Spectrum
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Látalová, A., Radimecká, M., Lamoš, M., Jáni, M., Damborská, A., Theiner, P., Bartečková, E., Bartys, P., Vlčková, H., Školiaková, K., et al. (2023) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-023-00240-1 · Cited by 12
“This may overlap with the invalidating environments often observed in the childhood of patients with BPD [12, 13].”
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“While trauma is strongly linked to BPD, it is not a sole factor, as its influence is compounded by genetic and additional environmental elements, suggesting that trauma alone does not invariably lead to the disorder [68].”
Lang, C. M., Edwards, A. J., Mittler, M. A., & Bonavitacola, L. (2018) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2017.12.005 · Cited by 9
Childhood trauma as a mediator between emotional intelligence and recidivism in male offenders
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Complex Post Traumatic Stress Disorder: A Review
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Long-Term and Bizarre Self-Injurious Behavior
Navinés, R., Gutiérrez, F., Arranz, B., Moreno-España, J., Imaz, M. L., Soler, V. G., Vázquez, M., Pascual, J. C., Martín‐Santos, R., & Kahn, D. A. (2013) · Journal of Psychiatric Practice · doi:10.1097/01.pra.0000426329.34149.b6 · Cited by 8
Neural correlates of fears of abandonment and rejection in borderline personality disorder
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History of child sexual abuse among women consuming illicit substances in Mexico City
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“…al., 2013), posttraumatic stress disorder (PTSD) (Chen et al., 2010; McLean & Gallop, 2003; Schoedl et al., 2010), borderline personality disorder (Ball & Links, 2009; Bandelow et al., 2005; McLean & Gallop, 2003), eating disorders (Smolak & Murnen, 2002; Wilson, 2010), and sleep disorders (Chen…”
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“Adverse childhood experience scores upon entry into the juvenile justice system may be one way to identify at- risk youth, as research has indicated that such experiences increase risk for the development of BPD features later in life [49,50].”
BackgroundSkaug, E., Czajkowski, N. O., Waaktaar, T., & Torgersen, S. O. (2022) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-022-00190-0 · Cited by 12
Complex dissociative disorders in social work: discovering the knowledge gaps
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“…profound support for people with mental disorders, especially those mental disorders which are highly related to psychosocial etiological factors, such as posttraumatic stress disorder (PTSD) (American Psychiatric Association, 2013) and borderline personality disorder (BPD) (Ball & Links, 2009).”
BackgroundEye movement desensitisation and reprocessing (EMDR) within prisons and the criminal justice system
Crole-Rees, C., Lawrence, D., Blundell, L., Saward, K., Jones, L., Anany, S. E., Simon, G., Kalebic, N., & Forrester, A. (2024) · Medicine Science and the Law · doi:10.1177/00258024241293540 · Cited by 7
“2 Trauma exposure, whenever it occurs during the lifespan, has been associated with the development of a range of serious mental disorders, 3,4 which are themselves overrepresented in criminal justice services.”
Ciringione, L., Perinelli, E., Mancini, F., & Prunetti, E. (2025) · Brain Sciences · doi:10.3390/brainsci15080889 · Cited by 7
“The link between dissociation and trauma is robust in both Borderline Personality Disorder (BPD) and Dissociative Disorders (DD; [28]), particularly when viewed within a multifactorial etiological framework.”
Karamanolaki, H., Spyropoulou, A. C., Iliadou, A., Vousoura, E., Vondikaki, S., Pantazis, N., & Vaslamatzis, G. (2016) · Bulletin of the Menninger Clinic · doi:10.1521/bumc.2016.80.3.234 · Cited by 8
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“Insecure attachment and persistent feelings of emptiness render a feeling of depression among individuals with BPDS [18].”
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Borderline Personality as a Disorder of Temporality–A Phenomenological Meta-Synthesis
Sterna, A., Moskalewicz, M., & Fuchs, T. A. E. (2025) · Human Studies · doi:10.1007/s10746-025-09784-3 · Cited by 11
Procter, N. G., Hamer, H. P., McGarry, D. E., Wilson, R. L., & Froggatt, T. (2018) · Cambridge University Press eBooks · doi:10.1017/9781316718278 · Cited by 6
Baryshnikov, I., Aaltonen, K. I., Suvisaari, J., Koivisto, M., Heikkinen, M. E., Joffe, G., & Isometsä, E. T. (2018) · European Psychiatry · doi:10.1016/j.eurpsy.2017.12.005 · Cited by 7
Childhood Trauma and Psychosis
Dvir, Y. (2021) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2021.08.002 · Cited by 6
Vulnerability to PTSD: Psychosocial and Demographic Risk and Resilience Factors
Bar‐Shai, M., & Klein, E. (2014) · Springer eBooks · doi:10.1007/978-1-4899-7522-5_1 · Cited by 6
Kouros, I., Holmberg, H., Ekselius, L., & Ramklint, M. (2023) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2023.2267041 · Cited by 5
Null, K. E., Duda, J. M., & Pizzagalli, D. A. (2024) · Journal of Mood and Anxiety Disorders · doi:10.1016/j.xjmad.2024.100057 · Cited by 5
“Childhood trauma has been linked to depression [10,11], anxiety [12], post-traumatic stress disorder [13], and borderline personality disorder [14,15].”
BackgroundDevelopment of Emotional Cascades in Borderline Personality Disorder
Selby, E. A., Kranzler, A., & Panza, E. A. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0591-1_12 · Cited by 5
Kramer, U., Meystre, C., Imesch, C., & Kolly, S. (2016) · Journal of Psychotherapy Integration · doi:10.1037/a0040044 · Cited by 5
“…OF THERAPY Introduction Unresolved traumatic experiences influence identity integration in clients presenting with borderline personality disorder (BPD; Ball & Links, 2009; Fossati, Maddedu, & Maffei, 1999; Golier, Yehuda, Bierer et al., 2003; Paris, 1998; Schmahl, & Bremner, 2006; Zanarini, 2000).”
Evren, C., Karabulut, V., Alnıak, İ., Evren, B., Carkci, O. H., Cengel, H. Y., Menekseoglu, P. O., Cetin, T., Bozkurt, M., & Umut, G. (2019) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2019.1595271 · Cited by 5
“e both BPD [10] and SUDs [11] were shown to be related to childhood trauma.”
BackgroundDiagnostische und behandlungsbezogene Klassifikation psychischer Traumafolgestörungen
Schellong, J. (2021) · PTT - Persönlichkeitsstörungen: Theorie und Therapie · doi:10.21706/ptt-25-3-163 · Cited by 5
Accuracy and Bias in Facial Trustworthiness Appraisals in Borderline Personality Disorder
Miano, A., Lustig, S., Meyerding, L., & Barnow, S. (2023) · Journal of Personality Disorders · doi:10.1521/pedi.2023.37.5.525 · Cited by 5
Genital self-mutilation in an attempt of suicide by a patient with a borderline personality
Aalouane, R., Rammouz, I., Hafidi, H., & Boujraf, S. (2013) · Journal of Neurosciences in Rural Practice · doi:10.4103/0976-3147.112769 · Cited by 5
“They are mostly associated to psychotic disorders compared to severe personality disorders.[1,2] Indeed, the self-mutilation act is characterizing the borderline personality disorder.”
InfluentialRojas, E. C., Hicks, B. M., Stark, S. E., Hopwood, C. J., & Bornovalova, M. A. (2015) · Psychological Assessment · doi:10.1037/pas0000061 · Cited by 5
Yuan, G. F., Lam, S. K. K., Celine Mylx, L. I., Yau, S. W., Wong, M. Y. C., & Fung, H. W. (2025) · European Journal of Psychotraumatology · doi:10.1080/20008066.2025.2562724 · Cited by 4
“In addition, a growing body of research has high-lighted the significant role of childhood trauma and adversities in the etiology of BPD among adults (Ball & Links, 2009; Fung, Wong, et al., 2023; Pohl et al., 2021).”
Stone, B. M. (2022) · Psychological Reports · doi:10.1177/00332941221127618 · Cited by 4
“…et al., 2017), 93% of individuals with BPD report at least one instance of childhood loss or abuse compared to 73% for the other personality disorders (Ball & Links, 2009), and that exposure to this early childhood abuse or neglect may result in the patients becoming high-risk later in life…”
Pedone, R., Pistone, L., Schettino, E. M., & Florio, G. (2025) · Mental Health & Prevention · doi:10.1016/j.mhp.2025.200429 · Cited by 6
Schauer, P. A., Rauh, J., Leicht, G., Andreou, C., & Mulert, C. (2019) · Brain Topography · doi:10.1007/s10548-019-00700-4 · Cited by 4
Kalapatapu, R. K., Patil, U., & Goodman, M. S. (2010) · Cyberpsychology Behavior and Social Networking · doi:10.1089/cyber.2009.0351 · Cited by 4
“While not currently a specific criterion, there is ample evidence of childhood abuse in the etiology of BPD, 21–23 and there is considerable debate between the overlap of BPD and PTSD. 24 In terms of the relationship between anxiety and BPD, a recent confirmatory factor analysis comparing five models…”
Bourgeois, C., Lecomte, T., McDuff, P., & Daigneault, I. (2020) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2020.104819 · Cited by 3
Bangash, F., Megna, J. L., & Leontieva, L. (2021) · Cureus · doi:10.7759/cureus.13179 · Cited by 4
“Additionally, a history of childhood physical/sexual abuse in conjunction with PTSD has been associated with BPD and self-harming behaviors [10].”
BackgroundGirard, M.-S., & Morizot, J. (2022) · Current Psychiatry Research and Reviews · doi:10.2174/2666082218666220816100950 · Cited by 5
Giugliano, J. R. (2012) · Clinical Case Studies · doi:10.1177/1534650112460428 · Cited by 4
False memory in posttraumatic stress disorder and borderline personality disorder
Miano, A., Schulze, K., Moritz, S., Wingenfeld, K., & Roepke, S. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114547 · Cited by 3
Ocisková, M., Praško, J. P., Kantor, K., Vaněk, J., Nesnídal, V., & Bělohradová, K. (2024) · Psychology Research and Behavior Management · doi:10.2147/prbm.s476768 · Cited by 3
Verwendung ökonomischer Spiele für die Diagnostik psychischer Erkrankungen
Kupferberg, A., Preuss, N., & Hasler, G. (2017) · Zeitschrift für Psychiatrie Psychologie und Psychotherapie · doi:10.1024/1661-4747/a000300 · Cited by 3
Metadata
- Authors
- Ball, J. S., & Links, P. S.
- Affiliations
- St. Michael's Hospital (CA)
- Corresponding author
- Ball, Jeffrey S.
- Venue
- Current Psychiatry Reports
- Published
- 2009-01-22
- Volume
- 11
- Issue
- 1
- Pages
- 63-68
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- OpenAlex
- W1994608326
- Cited by
- 320
- References
- 53
- Citations by year
- 2026: 10 · 2025: 18 · 2024: 25 · 2023: 11 · 2022: 26 · 2021: 31 · 2020: 26 · 2019: 33 · 2018: 22 · 2017: 10 · 2016: 20 · 2015: 22 · 2014: 21 · 2013: 17 · 2012: 10
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- borderline personality disorder, childhood trauma, causal relationship, etiology, multifactorial etiology, quality of evidence
- MeSH terms
- Adult, Borderline Personality Disorder, Brain, Child, Child Abuse, Child Abuse, Sexual, Cross-Sectional Studies, Humans, Interpersonal Relations, Life Change Events, Object Attachment, Risk Factors, Self Concept, Causality
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