The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“collagen is also rich in the amino acid glycine, which may be conditionally essential in humans due to a suggested deficiency in the ability of the liver and kidney to synthesize sufficient amounts in humans to satisfy the metabolic demand for collagen synthesis [163].”
From Protein Requirements for Master Athletes: Just Older Versions of Their Younger Selves (2021) · cites this paper as [163]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kleiber, M. (1947) · Physiological Reviews · doi:10.1152/physrev.1947.27.4.511 · Cited by 1,817
Miller, B. F., Olesen, J. L., Hansen, M., Døssing, S., Crameri, R. M., Welling, R. J., Langberg, H., Flyvbjerg, A., Kjaer, M., Babraj, J. A., et al. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.093690 · Cited by 610
Precambrian Sponges with Cellular Structures
Li, C.-W., Chen, J.-Y., & Hua, T.-E. (1998) · Science · doi:10.1126/science.279.5352.879 · Cited by 489
CARNITINE METABOLISM AND ITS REGULATION IN MICROORGANISMS AND MAMMALS
Rebouche, C. J., & Seim, H. (1998) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.18.1.39 · Cited by 362
Is it time to reevaluate methyl balance in humans?
Stead, L. M., Brosnan, J. T., Brosnan, M. E., Vance, D. E., & Jacobs, R. L. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.1.5 · Cited by 278
Review lecture. The blood‐brain barrier.
Davson, H. (1976) · The Journal of Physiology · doi:10.1113/jphysiol.1976.sp011267 · Cited by 219
Research works printed but not linked: 112
- Ackernecht E H 1953 Paleopathology, in Anthropology today: an encyclopedic inventory (ed.) A L Kroeber (Chicago, IL: University of Chicago Press)
- Aouacheria A, Geourjon C, Aghajari N, Navratil V, Deléage G, Lethias C and Exposito J-Y 2006 Insights into early extracellular matrix evolution: spongin short chain collagen-related proteins are homologous to basement membrane type IV collagens and form a novel family widely distributed in invertebrates; Mol. Biol. Evol. 23 2288–2302 · DOI
- Atencia L J, McDevitt C A, Nile W B and Sokoloff L 1989 Cartilage content of an immature dog; Connect. Tissue Res. 18 235–242 · DOI
- Babraj J A, Smith K, Cuthbertson D J, Rickhuss P, Dorling J S and Rennie M J 2005 Human bone collagen synthesis is a rapid nutritionally modulated process; J. Bone Miner. Res. 20 930–937 · DOI
- Baker P R S, Cramer S D, Kennedy M, Assimos D G and Holmes R P 2004 Glycolate and glyoxylate metabolism in HepG2 cells; Am. J. Physiol. 287 C1359–C1365 · DOI
- Baños G, Daniel P M, Moorhouse S R and Pratt O E 1975 The requirements of the brain for some amino acids; J. Physiol. 246 539–548 · DOI
- Baserga R 1976 Multiplication and division in mammalian cells (New York: Marcel Dekker Inc.)
- Behnam J T, Williams E L, Brink S, Rumsby G and Danpure C J 2006 Reconstruction of human hepatocyte glyoxylate metabolic pathways in stably transformed Chinese-hamster ovary cells; Biochem. J. 394 409–416 · DOI
- Berg R A, Schwartz M L and Crystal R G 1980 Regulation of the production of secretory proteins: intracellular degradation of newly synthesized ‘defective’ collagen; Proc. Natl. Acad. Sci. USA 77 4746–4750 · DOI
- Bhide V M, Laschinger C A, Arora P D, Lee W, Hakkinen L, Larjava H, Sodek J and McCulloch C A 2005 Collagen phagocytosis by fibroblasts is regulated by decorin; J. Biol. Chem. 280 23103–23113 · DOI
- Bienkowski R S 1983 Intracellular degradation of newly synthesized secretory proteins; Biochem. J. 214 1–10 · DOI
- Bienkowski R S and Engels C J 1981 Measurement of intracellular collagen degradation; Anal. Biochem. 116 414–424 · DOI
- Bienkowski R S, Baum B J and Crystal R G 1978a Fibroblasts degrade newly synthesised collagen within the cell before secretion; Nature (London) 276 413–416 · DOI
- Bienkowski R S, Cowan M J, McDonald J A and Crystal R G 1978b Degradation of newly synthesized collagen; J. Biol. Chem. 253 4356–4363 · DOI
- Blair H C, Zaidi M and Schlesinger P H 2002 Mechanisms balancing skeletal matrix synthesis and degradation; Biochem. J. 364 329–341 · DOI
- Block R J and Weiss K W 1956 Amino acid handbook. Methods and results of protein analysis (Springfield Ill: Charles C Thomas)
- Boudier C, Holle C and Bieth J G 1981 Stimulation of the elastolytic activity of leukocyte elastase by leukocyte cathepsin G; J. Biol. Chem. 256 10256–10258 · DOI
- Bowering J, Calloway D H, Margen S and Kaufmann N A 1970 Dietary protein level and uric acid metabolism in normal man; J. Nutr. 100 249–261 · DOI
- Bradley K, McConnell-Breul D and Crystal R G 1975 Collagen in the human lung. Quantitation of rates of synthesis and partial characterization of composition; J. Clin. Invest. 55 543–550 · DOI
- Brawley L, Torrens C, Anthony F W, Itoh S, Wheeler T, Jackson A A, Clough, G F, Poston, L and Hanson M A 2003 Glycine rectifies vascular dysfunction induced by dietary protein imbalance during pregnancy; J. Physiol. 554 497–504 · DOI
- Case G L and Benevenga N J 1977 Significance of formate as an intermediate in the oxidation of the methionine S-methyl-L-cysteine and sarcosine methyl carbons to CO2 in the rat; J. Nutr. 107 1665–1676 · DOI
- Christensen H N 1982 Interorgan amino acid nutrition; Physiol. Rev. 62 1193–1233 · DOI
- Cook R J and Wagner C 1984 Glycine N-methyltransferase is a folate binding protein of rat liver cytosol; Proc. Natl. Acad. Sci. USA 81 3631–3634 · DOI
- Cornish-Bowden A, Hofmeyr J-H S and Cárdenas M L 1995 Strategies for manipulating metabolic fluxes in biotechnology; Bioorg. Chem. 23, 439–449 · DOI
- Crawhall J C and Watts R W 1962 The metabolism of glyoxylate by human- and rat-liver mitochondria; Biochem. J. 85 163–171 · DOI
- Daughaday W H and Mariz I K 1962 The formation of free hydroxyproline by rat cartilage in vitro; J. Biol. Chem. 237 2831–2835 · DOI
- Davis S R, Stacpoole P W, Williamson J, Kick L S, Quinlivan E P, Coats B S, Shane B, Bailey L B and Gregory J F 3rd 2004 Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor; Am. J. Physiol. 286 E272–E279 · DOI
- de Koning T J, Duran M, Dorland L, Gooskens R, Van Schaftingen E, Jaeken J, Blau N, Berger R and Poll-The B T 1998 Beneficial effects of l-serine and glycine in the management of seizures in 3-phosphoglycerate dehydrogenase deficiency; Ann. Neurol. 44 261–265 · DOI
- Duggleby S L and Waterlow J C 2005 The end-product method of measuring whole-body protein turnover: a review of published results and a comparison with those obtained by leucine infusion; Br. J. Nutr. 94 141–153 · DOI
- el-Harake W A, Furman M A, Cook B, Nair K S, Kukowski J and Brodsky I G 1998 Measurement of dermal collagen synthesis rate in vivo in humans; Am. J. Physiol. 274 E586–E591 · DOI
- Eyre D R, Weis M A and Wu J J 2006 Articular cartilage collagen: an irreplaceable framework? Eur. Cell. Mater. 12 57–63 · DOI · Paper page
- FAO/WHO/UNU 1985 Energy and protein requirements; FAO/ WHO/UNU Tech. Rep. Ser. 724 1–206
- Fell D 1997 Understanding the control of metabolism (London: Portland Press)
- Fern E B and Garlick P J 1973 The specific radioactivity of the precursor pool for estimates of the rate of protein synthesis; Biochem. J. 134 1127–1130 · DOI
- Fern E B, Garlick P J and Waterlow J C 1985 Apparent compartmentation of body nitrogen in one human subject: its consequences in measuring the rate of whole-body protein synthesis with 15N; Clin. Sci. (London) 68 271–282 · DOI
- Finkelstein J S 2004 Osteoporosis; in Cecil textbook of medicine (Philadelphia: Saunders) pp 147–155
- Flanagan B and Nichols G 1969 Bone matrix turnover and balance in vitro II, the effects of ageing; J. Clin. Invest. 48 607–612 · DOI
- Fukagawa N K, Ajami A M and Young V R 1996 Plasma methionine and cysteine kinetics in response to an intravenous glutathione infusion in adult humans; Am. J. Physiol. 270 E209–E214
- Gibson N R, Jahoor F, Ware L and Jackson A A 2002 Endogenous glycine and tyrosine production is maintained in adults consuming a marginal-protein diet; Am. J. Clin. Nutr. 75 511–518 · DOI
- Hance A J, Bradley K and Crystal R G 1976 Lung collagen heterogeneity. Synthesis of type I and type III collagen by rabbit and human lung cells in culture; J. Clin. Invest. 57 102–111 · DOI
- Hofmeyr J-H S and Cornish-Bowden A 2000 Regulating the cellular economy of supply and demand; FEBS Lett. 476 47–51 · DOI
- House J D, Hall B N and Brosnan J T 2001 Threonine metabolism in isolated rat hepatocytes; Am. J. Physiol. 281 E1300–E1307 · DOI
- Huang W 1977 Chemical and histochemical studies of human alveolar collagen fibers; Am. J. Pathol. 86 81–97
- Inoue K, Mikuni-Takagaki Y, Oikawa K, Itoh T, Inada M, Noguchi T, Park J S, Onodera T, Krane S M, Noda M and Itohara S 2006 A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism; J. Biol. Chem. 281 33814–33824 · DOI
- Jackson A A 1991 The glycine story; Eur. J. Clin. Nutr. 45 59–65
- Jackson A A, Badaloo A V, Forrester T, Hibbert J M and Persaud C 1987 Urinary excretion of 5-oxoproline (pyroglutamic aciduria) as an index of glycine insufficiency in normal man; Br. J Nutr. 58 207–214 · DOI
- Jackson A A, Persaud C, Meakins T S and Bundy R 1996 Urinary excretion of 5-L-oxoproline (pyroglutamic acid) is increased in normal adults consuming vegetarian or low protein diets; J. Nutr. 126 2813–2822 · DOI
- Jackson A A, Dunn R L, Marchand MC and Langley-Evans S C 2002 Increased systolic blood pressure in rats induced by a maternal low-protein diet is reversed by dietary supplementation with glycine; Clin. Sci. (London). 103 633–639 · DOI
- Johnson H A, Baldwin R L, France J and Calvert C C 1999 A model of whole-body protein turnover based on leucine kinetics in rodents; J. Nutr. 129 728–739 · DOI
- Kadler K E, Holmes D F, Trotter J A and Chapman J A 1996 Collagen fibril formation; Biochem. J. 316 1–11 · DOI · Paper page
- Keeley F W and Johnson D J 1983 Measurement of the absolute synthesis of soluble and insoluble elastin by chick aortic tissue; Can. J. Biochem. Cell. Biol. 61 1079–1084 · DOI
- Kopple J D and Swendseid M E 1975 Evidence that histidine is an essential amino acid in normal and chronically uremic man; J. Clin. Invest. 55 881–891 · DOI
- Krane S M, Byrne M H, Lemaitre V, Henriet P, Jeffrey J J, Witter J P, Liu X, Wu H, Jaenisch R and Eeckhout Y 1996 Different collagenase gene products have different roles in degradation of type I collagen; J. Biol. Chem. 271 28509–28515 · DOI
- Krebs H A, Hems R and Tyler B 1976 The regulation of folate and methionine metabolism; Biochem. J. 158 341–353 · DOI
- Laurent G J 1982 Rates of collagen synthesis in lung skin and muscle obtained in vivo by a simplified method using [3H]proline; Biochem. J. 206 535–544 · DOI
- Lewis R M, Godfrey K M, Jackson A A, Cameron I T and Hanson M A 2005 Low serine hydroxy-methyltransferase activity in the human placenta has important implications for fetal glycine supply; J. Clin. Endocrinol. Metab. 90 1594–1598 · DOI
- Li X, Bradford B U, Wheeler M D, Stimpson S A, Pink, H M, Brodie T A, Schwab J H and Thurman R G 2001 Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel; Infect. Immun. 69 5883–5891 · DOI
- Lohmander L S, Yoshihara Y, Roos H, Kobayashi T, Yamada H and Shinmei M 1996 Procollagen II C-propeptide in joint fluid: changes in concentration with age, time after knee injury, and osteoarthritis; J. Rheumatol. 23 1765–1769
- Lohmander L S, Atley L M, Pietka T A and Eyre D R 2003 The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis; Arthr. Rheum. 48 3130–3139 · DOI · Paper page
- London I M, West R, Shemin D and Rittenberg D 1950 On the origin of bile pigment in normal man; J. Biol. Chem. 184 351–358 · DOI
- Lowry O H, Gilligan D R and Katersky E M 1941 The determination of collagen and elastin in tissues with results obtained in various normal tissues from different species; J. Biol. Chem. 139 795–804 · DOI · Paper page
- Lucattelli M, Cavarra E, de Santi M M, Tetley T D, Martorana P A and Lungarella G 2003 Collagen phagocytosis by lung alveolar macrophages in animal models of emphysema; Eur. Respir. J. 22 728–734 · DOI
- Lumb M, Chanarin I, Deacon R and Perry J 1988 In vivo oxidation of the methyl group of hepatic 5-methyltetrahydrofolate; J. Clin. Pathol. 41 1158–1162 · DOI
- Lumb M, Bottiglieri T, Deacon R, Perry J and Chanarin I 1989a Regulation of 5-methyltetrahydrofolate synthesis; Biochem. J. 258 611–612 · DOI
- Lumb M, Deacon R, Perry J and Chanarin I 1989b Oxidation of 5-methyltetrahydrofolate in cobalamin-inactivated rats; Biochem. J. 258 907–910 · DOI
- Mahan B R 1978 Osteoarthrosis in a coyote × dog hybrid from Nebraska; J. Wildl. Dis. 14 395–398 · DOI
- Martini W Z, Chinkes D L and Wolfe R R 2004 The intracellular free amino acid pool represents tracer precursor enrichment for calculation of protein synthesis in cultured fibroblasts and myocytes; J. Nutr. 134 1546–1550 · DOI
- Mays P K, McAnulty R J, Campa J S and Laurent G J 1991 Age-related changes in collagen synthesis and degradation in rat tissues. Importance of degradation of newly synthesized collagen in regulating collagen production; Biochem. J. 276 307–313 · DOI
- McMartin K E, Martin-Amat G, Makar A B and Tephly T R 1977 Methanol poisoning. V. Role of formate metabolism in the monkey; J. Pharmacol. Exp. Theor. 201 564–572 · DOI
- Meléndez-Hevia E and de Paz-Lugo P 2008 Branch-point stoichiometry can generate weak links in metabolism: the case of glycine biosynthesis; J. Biosci. 33 771–780 · DOI
- Meisenberg G and Simmons W H 1998 Principles of medical biochemistry (St Louis, MO: Mosby)
- Meister A 1988 Glutathione metabolism and its selective modification; J. Biol. Chem. 263 17205–17208 · DOI · Paper page
- Mizuno K, Hayashi T and Bachinger H P 2003 Hydroxylation-induced stabilization of the collagen triple helix. Further characterization of peptides with 4(R)-hydroxyproline in the Xaa position; J. Biol. Chem. 278 32373–32379 · DOI
- Mudd S H and Poole J R 1975 Labile methyl balances for normal humans on various dietary regimens; Metabolism 24 721–735 · DOI · Paper page
- Mudd S H, Ebert M H and Scriver C R 1980 Labile methyl group balances in the human: the role of sarcosine; Metabolism 29 707–720 · DOI
- Mudd S H, Cerone R, Schiaffino M C, Fantasia A R, Minniti G, Caruso U, Lorini R, Watkins D, et al. 2001 Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia; J. Inherit. Metab. Dis. 24 448–464 · DOI
- Mudd S H, Brosnan J T, Brosnan M E, Jacobs R L, Stabler S P, Allen R H, Vance D E and Wagner C 2007 Methyl balance and transmethylation fluxes in humans; Am. J. Clin. Nutr. 85 19–25 · DOI
- N’Diaye F, Hitier Y, Courcy G P d, Goubern M and Bourdel G 1980 Methionine synthesis aminoimidazole carboxamide excretion and folate levels in pregnant rats; J. Nutr. 110 522–531 · DOI
- Neuman R E and Logan M A 1950 The determination of collagen and elastin in tissues; J. Biol. Chem. 186 549–556 · DOI · Paper page
- Nissim I and Lapidot A 1979 Plasma amino acid turnover rates and pools in rabbits: in vivo studies using stable isotopes; Am. J. Physiol. 237 E418–E427
- Nissim I, Yudkoff M and Segal S 1983 A model for determination of total body protein synthesis based upon compartmental analysis of the plasma [15N] glycine decay curve; Metabolism 32 646–653 · DOI
- Norton J A, Stein T P and Brennan M F 1981 Whole body protein synthesis and turnover in normal man and malnourished patients with and without known cancer; Ann. Surg. 194 123–128 · DOI
- Palmer R M, Robins S P and Lobley G E 1980 Measurement of the synthesis rates of collagens and total protein in rabbit muscle; Biochem. J. 192 631–636 · DOI
- Parimi P S, Gruca L L and Kalhan S C 2005 Metabolism of threonine in newborn infants; Am. J. Physiol. 289 E981–E985
- Passeri G, Pini G, Troiano L, Vescovini R, Sansoni P, Passeri M, Gueresi P, Delsignore R, Pedrazzoni M and Franceschi C 2003 Low vitamin D status, high bone turnover, and bone fractures in centenarians; J. Clin. Endocrinol. Metab. 88 5109–5115 · DOI
- Perret S, Merle C, Bernocco S, Berland P, Garrone R, Hulmes D J, Theisen M and Ruggiero F 2001 Unhydroxylated triple helical collagen I produced in transgenic plants provides new clues on the role of hydroxyproline in collagen folding and fibril formation; J. Biol. Chem. 276 43693–43698 · DOI
- Persaud C, Forrester T and Jackson A A 1996 Urinary excretion of 5-l-oxoproline (pyroglutamic acid) is increased during recovery from severe childhood malnutrition and responds to supplemental glycine; J. Nutr. 126 2823–2830 · DOI
- Pierce J A and Hocott J B 1960 Studies on the collagen and elastin content of the human lung; J. Clin. Invest. 39 8–14 · DOI
- Rebouche C J and Engel A G 1984 Kinetic compartmental analysis of carnitine metabolism in the human carnitine deficiency syndromes. Evidence for alterations in tissue carnitine transport; J. Clin. Invest. 73 857–867 · DOI
- Rebouche C J, Lombard K A and Chenard C A 1993 Renal adaptation to dietary carnitine in humans; Am. J. Clin. Nutr. 58 660–665 · DOI · Paper page
- Repo R U and Mitchell N 1971 Collagen synthesis in mature articular cartilage of the rabbit; J. Bone Joint Surg. 53 541–548 · DOI
- Reynolds W W and Karlotski W J 1977 The allometric relationship of skeleton weight to body weight in teleost fishes: a preliminary comparison with birds and mammals; Copeia 1977 160–163 · DOI
- Rogers H J, Weidmann S M and Parkinson A 1952 Studies on the skeletal tissues. II. The collagen content of bones from rabbits oxen and humans; Biochem. J. 50 537–542 · DOI
- Rosenbloom J, Abrams W R and Mecham R 1993 Extracellular matrix 4: the elastic fiber; FASEB. J. 7 1208–1218 · DOI · Paper page
- Rucker R B and Dubick M A 1984 Elastin metabolism and chemistry: potential roles in lung development and structure; Environ. Health Perspect. 55 179–191 · DOI
- Ruiz-Torres A and Kürten I 1976 Is there a recycling of hydroxyproline?; Experientia 32 555–656 · DOI
- Salido E C, Li X M, Lu Y, Wang X, Santana A, Roy-Chowdhury N, Torres A, Shapiro L J and Roy-Chowdhury J 2006 Alanineglyoxylate aminotransferase-deficient mice a model for primary hyperoxaluria that responds to adenoviral gene transfer; Proc. Natl. Acad. Sci. USA 103 18249–18254 · DOI
- Shapiro S D, Endicott S K, Province M A, Pierce J A and Campbell E J 1991 Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of d-aspartate and nuclear weapons-related radiocarbon; J. Clin. Invest. 87 1828–1834 · DOI · Paper page
- Schneir M L, Ramamurthy N S and Golub L M 1984 Extensive degradation of recently synthesized collagen in gingiva of normal and streptozotocin-induced diabetic rats; J. Dent. Res. 63 23–27 · DOI
- Stifel F B and Herman R H 1972 Is histidine an essential amino acid in man? Am. J. Clin. Nutr. 25 182–185 · DOI
- Taheri M R, Wickremasinghe R G and Hoffbrand A V 1981 Alternative metabolic fates of thymine nucleotides in human cells; Biochem. J. 194 451–461 · DOI
- Tobin D J 2006 Biochemistry of human skin — our brain on the outside; Chem. Soc. Rev. 35 52–67 · DOI · Paper page
- Van Venrooij W J, Moonen H and Van Loon-Klaassen L 1974 Source of amino acids used for protein synthesis in HeLa cells; Eur. J. Biochem. 50 297–304 · DOI
- Vaz F M and Wanders R J 2002 Carnitine biosynthesis in mammals; Biochem. J. 361 417–429 · DOI · Paper page
- Waterlow J C 1984 Protein turnover with special reference to man; Q. J. Exp. Physiol. 69 409–438 · DOI · Paper page
- Waterlow J C 2006 Protein turnover (Wallingford, UK: CABI Publishing) pp 270–274 · DOI
- Weissengruber G E, Fuss F K, Egger G, Stanek, G, Hittmair, K M and Forstenpointner G 2006 The elephant knee joint: morphological and biomechanical considerations; J. Anat. 208 59–72 · DOI
- Wise E M Jr and Elwyn D 1965 Rates of reactions involved in phosphatide synthesis in liver and small intestine of intact rats; J. Biol. Chem. 240 1537–1548 · DOI
- Woessner J F Jr 1991 Matrix metalloproteinases and their inhibitors in connective tissue remodelling; FASEB J. 5 2145–2154 · DOI · Paper page
- Woessner J F and Brewer T H 1963 Formation and breakdown of collagen and elastin in the human uterus during pregnancy and post-partum involution; Biochem. J. 89 75–82 · DOI
- Yeung Y G 1986 l-Threonine aldolase is not a genuine enzyme in rat liver; Biochem. J. 237 187–190 · DOI
- Young V R and Pellett P L 1987 Protein intake and requirements with reference to diet and health; Am. J. Clin. Nutr. 45 1323–1343 · DOI
Cited by
Glycine metabolism in animals and humans: implications for nutrition and health
Wang, W., Wu, Z., Dai, Z., Yang, Y., Wang, J., & Wu, G. (2013) · Amino Acids · doi:10.1007/s00726-013-1493-1 · Cited by 766
Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function
Hertzler, S. R., Lieblein-Boff, J. C., Weiler, M., & Allgeier, C. (2020) · Nutrients · doi:10.3390/nu12123704 · Cited by 594
The gut microbiota influences skeletal muscle mass and function in mice
Lahiri, S., Kim, H., Garcia-Perez, I., Reza, M. M., Martin, K. A., Kundu, P., Cox, L. M., Selkrig, J., Posma, J. M., Zhang, H., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aan5662 · Cited by 580
Holwerda, A. M., & van Loon, L. J. C. (2022) · Nutrition Reviews · doi:10.1093/nutrit/nuab083 · Cited by 117
Sekhar, R. V. (2021) · The Journal of Nutrition · doi:10.1093/jn/nxab309 · Cited by 42
Metadata
- Authors
- Meléndez-Hevia, E., de Paz-Lugo, P., Cornish-Bowden, A., & Cárdenas, M. L.
- Venue
- Journal of Biosciences
- Published
- 2009-12
- Volume
- 34
- Issue
- 6
- Pages
- 853-872
- ISSN
- 0250-5991
- 0973-7138
- Cited by
- 136
- References
- 6
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. https://app.cochat.ai/papers/10.1007/s12038-009-0100-9
- The paper
- Meléndez-Hevia, E., de Paz-Lugo, P., Cornish-Bowden, A., & Cárdenas, M. L. (2009). A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. Journal of Biosciences. https://doi.org/10.1007/s12038-009-0100-9
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.