The relationship between childhood trauma, early-life stress, and alcohol and drug use, abuse, and addiction: An integrative review
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Prolonged exposure to stress can lead to irregular changes in GC receptor density which may increase the reinforcing effects of alcohol and drugs.
“Prolonged exposure to stress can lead to irregular changes in GC receptor density (epigenetics) which may increase the reinforcing effects of alcohol and drugs [177,178].”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [177]
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Wiss, D. A., Avena, N., & Gold, M. (2020) · Nutrients · doi:10.3390/nu12113521 · Cited by 66 · see citing works
- Authors
- Moustafa, A. A., Parkes, D., Fitzgerald, L., Underhill, D., Garami, J., Levy-Gigi, E., Stramecki, F., Valikhani, A., Frydecka, D., & Misiak, B.
- Affiliations
- Western Sydney University (AU)
- Shiraz University (IR)
- Wroclaw Medical University (PL)
- Corresponding author
- Moustafa, Ahmed A.
- Venue
- Current Psychology
- Published
- 2018-08-28
- Volume
- 40
- Issue
- 2
- Pages
- 579-584
- ISSN
- 1046-1310 (ISSN-L)
- 1936-4733
- OpenAlex
- W2889304095
- Cited by
- 128
- References
- 48
- Citations by year
- 2026: 10 · 2025: 28 · 2024: 24 · 2023: 26 · 2022: 18 · 2021: 12 · 2020: 6 · 2019: 4
- FWCI
- 6.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Psychology (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Keywords
- childhood trauma, early life stress, substance use, alcohol abuse, drug abuse, addiction, relapse, neural mechanisms, treatment options
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