The long-term effects of childhood maltreatment experiences on subsequent illicit drug use and drug-related problems in young adulthood
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Objectives The objective of this study was to examine the associations between (a) childhood maltreatment (i.e., physical abuse, sexual abuse, and neglect) and subsequent illicit drug use and (b) childhood maltreatment and drug-related problems in young adulthood.Methods Wave 1 and Wave 3 public-use data from the National Longitudinal Study of Adolescent Health were used. Logistic regressions, controlling for adolescent drug use and other important family and peer contextual processes, were estimated to determine the associations between (a) childhood maltreatment experiences and subsequent illicit drug use and (b) childhood maltreatment and drug-related problems in young adulthood.Results Among the participants, 31.9% reported some form of childhood maltreatment. Childhood physical abuse was associated with a 37% (OR=1.37; 95% CI=1.04, 1.80) increase in illicit drug use during the 30 days prior to the Wave 3 survey, a 48% (OR=1.48; 95% CI=1.16, 1.89) increase in illicit drug use during the year prior to the Wave 3 survey, and a 96% (OR=1.96; 95% CI=1.40, 2.76) increase in drug-related problems in young adulthood. The latter two associations persisted even after controlling for illicit drug use in adolescence. Neglect among females was associated with a higher likelihood of past year illicit drug use in young adulthood (OR=1.31; 95% CI=1.002, 1.71). However, this association was not significant once the effect of illicit drug use in adolescence was statistically controlled for.Conclusions The present findings suggest that childhood maltreatment is related to subsequent illicit drug use and drug-related problems in young adulthood and that some of these associations differ by gender. Implications for preventive intervention are discussed.
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The relationship between ACEs and subsequent SUD development might be partially mediated by a coping mechanism or a self-mediation strategy through which victims deal with feelings associated with childhood maltreatment.
“The relationship between ACEs and subsequent SUD development might be partially mediated by a coping mechanism or a self-mediation strategy throughout which victims deal with their feelings associated with childhood maltreatment (Huang et al., 2011).”
From Adverse childhood experiences (ACEs) and substance use disorder (SUD): A scoping review (2021) · cites this paper as Huang et al., 2011
The Discussion proposes that substance use may be a coping or self-medication strategy for feelings associated with childhood maltreatment. But the Limitations section says the study did not investigate drug abuse or dependence in young adulthood, so it does not establish this mechanism for subsequent SUD development. (LLM, conf=0.88)
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- Authors
- Huang, S., Trapido, E., Fleming, L., Arheart, K., Crandall, L., French, M., Malcolm, S., & Prado, G.
- Affiliations
- University of Miami (US)
- Louisiana State University (US)
- Clemson University (US)
- Corresponding author
- Huang, Shi
- ORCID
- Venue
- Addictive Behaviors
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 36
- Issue
- 1-2
- Pages
- 95-102
- ISSN
- 0306-4603 (ISSN-L)
- PMC
- PMC2993314
- OpenAlex
- W2004242051
- Cited by
- 125
- References
- 53
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 2 · 2023: 8 · 2022: 6 · 2021: 10 · 2020: 12 · 2019: 9 · 2018: 13 · 2017: 8 · 2016: 8 · 2015: 11 · 2014: 11 · 2013: 5 · 2012: 7
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Addictive Behaviors (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Drug Abuse (R01DA017462, DA017462)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD031921)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Safety Research › Child Welfare and Adoption
- Keywords
- child abuse, physical abuse, sexual abuse, neglect, illicit drug use, drug-related problems, early adulthood, adolescent drug use, gender differences, long-term effects, preventive interventions
- MeSH terms
- Adolescent, Child, Child Abuse, Female, Humans, Longitudinal Studies, Male, Risk Factors, Sex Factors, Illicit Drugs, United States, Substance-Related Disorders, Young Adult
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