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Cited by 171

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Injectable Materials for the Treatment of Myocardial Infarction and Heart Failure: The Promise of Decellularized Matrices

Open access
Singelyn, Jennifer M., Christman, Karen L.·2010·Journal of Cardiovascular Translational Research

Abstract

Cardiovascular disease continues to be the leading cause of death, suggesting that new therapies are needed to treat the progression of heart failure post-myocardial infarction. As cardiac tissue has a limited ability to regenerate itself, experimental biomaterial therapies have focused on the replacement of necrotic cardiomyocytes and repair of the damaged extracellular matrix. While acellular and cellular cardiac patches are applied surgically to the epicardial surface of the heart, injectable materials offer the prospective advantage of minimally invasive delivery directly into the myocardium to either replace the damaged extracellular matrix or to act as a scaffold for cell delivery. Cardiac-specific decellularized matrices offer the further advantage of being biomimetic of the native biochemical and structural matrix composition, as well as the potential to be autologous therapies. This review will focus on the requirements of an ideal scaffold for catheter-based delivery as well as highlight the promise of decellularized matrices as injectable materials for cardiac repair.

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Metadata

Authors
Singelyn, J. M., & Christman, K. L.
Venue
Journal of Cardiovascular Translational Research
Published
2010-07-15
Volume
3
Issue
5
Pages
478-486
ISSN
  • 1937-5387 (ISSN-L)
  • 1937-5395
OpenAlex
W2120097468
Cited by
171
References
4
FWCI
12.73
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Injectable Materials for the Treatment of Myocardial Infarction and Heart Failure: The Promise of Decellularized Matrices. https://app.cochat.ai/papers/10.1007/s12265-010-9202-x
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Singelyn, J. M., & Christman, K. L. (2010). Injectable Materials for the Treatment of Myocardial Infarction and Heart Failure: The Promise of Decellularized Matrices. Journal of Cardiovascular Translational Research. https://doi.org/10.1007/s12265-010-9202-x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.