Multiple somatic symptoms predict impaired health status in functional somatic syndromes
Abstract
Background The relationship between functional somatic syndromes and multiple somatic symptoms is unclear.Purpose We assessed whether the number of somatic symptoms is a predictor of health status in three functional somatic syndromes (FSS).Methods In a population-based study of 990 UK adults we assessed chronic widespread pain (CWP), chronic fatigue (CF) and irritable bowel syndrome (IBS) by questionnaire and medical record data. We assessed health status (Short Form 12 and EQ-5D), number of somatic symptoms (Somatic Symptom Inventory) and anxiety/depression (Hospital Anxiety and Depression Scale) both at baseline and at follow-up 1 year later.Results The proportion of people with an FSS who also have multiple somatic symptoms (52-55 %) was similar in the three functional syndromes. The presence of multiple somatic symptoms was associated with more impaired health status both at baseline and at follow-up. This finding was not explained by severity of FSS. In the absence of multiple somatic symptoms, the health status of the FSS was fair or good. In multiple regression analysis, the number of somatic symptoms, the presence of a functional syndrome (CWP or CF) and anxiety/depression were predictors of EQ-5D thermometer at follow-up after adjustment for confounders.Conclusions Multiple somatic symptoms in people with an FSS are associated with impaired health status and this cannot be explained by more severe functional syndrome or the presence of anxiety and depression.
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Functional somatic disorder multi-organ type affects an estimated 2% of the general population in Denmark.
“FSD multi-organ type affects an estimated 2% of the general population in Denmark and represents patients moderately to severely impaired by their illness [11,12].”
From Internet-delivered treatment for patients suffering from severe functional somatic disorders: Protocol for a randomized controlled trial (2023) · cites this paper as [11]
Functional somatic disorder multi-organ type represents patients moderately to severely impaired by their illness.
“FSD multi-organ type affects an estimated 2% of the general population in Denmark and represents patients moderately to severely impaired by their illness [11,12].”
From Internet-delivered treatment for patients suffering from severe functional somatic disorders: Protocol for a randomized controlled trial (2023) · cites this paper as [11]
Adult patients presenting with multiple symptoms from several organ systems have a poorer prognosis and a higher risk of chronification.
“Moreover, adult patients presenting with multiple symptoms from several organ systems have a poorer prognosis and a higher risk of chronification.22–24”
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- Authors
- Creed, F. H., Tomenson, B., Chew-Graham, C., Macfarlane, G. J., Davies, I., Jackson, J., Littlewood, A., & McBeth, J.
- Affiliations
- University of Manchester (GB)
- University of Aberdeen (GB)
- Corresponding author
- Creed, F. H.
- Venue
- International Journal of Behavioral Medicine
- Published
- 2012-08-30
- Volume
- 20
- Issue
- 2
- Pages
- 194-205
- ISSN
- 1070-5503 (ISSN-L)
- 1532-7558
- OpenAlex
- W2084972551
- Cited by
- 63
- References
- 88
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 3 · 2023: 2 · 2022: 5 · 2021: 4 · 2020: 8 · 2019: 7 · 2018: 7 · 2017: 1 · 2016: 4 · 2015: 7 · 2014: 5 · 2013: 2 · 2012: 1
- FWCI
- 3.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Journal of Behavioral Medicine (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- ePrints Soton (University of Southampton) (acceptedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Keywords
- functional somatic syndromes, somatic symptoms, health status, chronic widespread pain, chronic fatigue, irritable bowel syndrome, anxiety, depression, quality of life, EQ-5D, Short Form-12
- MeSH terms
- Anxiety, Depression, Female, United Kingdom, Health Status, Humans, Male, Middle Aged, Prospective Studies, Surveys and Questionnaires, Regression Analysis, Somatoform Disorders, Syndrome, Fatigue Syndrome, Chronic, Irritable Bowel Syndrome, Chronic Pain, Symptom Assessment
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