A review of melanin sensor devices
Open accessAbstract
Knowing how readily the skin produces melanin is invaluable in reducing photochemical and phototherapy overtreatment in dermatology and also in reducing the risk of actinic skin damage and skin cancer from excessive radiant light exposure. The commonly used Fitzpatrick skin type (FST) classification scale is often used to subjectively assess ultraviolet light sensitivity and susceptibility to sunburn following significant sunlight exposure. However, the FST scale falls short in the assessment of nonwhite skin types. Alternatively, commercially available melanin sensor devices, called melanometers, can be used to objectively quantify useful skin parameters such as the epidermal melanin concentration (EMC). This study reviews commercially available melanometers and their use in quantifying epidermal melanin concentration (EMC) and the individual maximum safe radiant exposure (IMSRE) for an individual in clinical, workplace and community settings.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The Fitzpatrick skin type scale is unreliable for darker skin, does not take into account skin color ranges, and does not accurately provide skin cancer risk, leading to healthcare disparities.
“The FST scale has been found to be unreliable for darker skin, not taking into account skin color ranges nor accurately providing skin cancer risk, ultimately leading to healthcare disparities.13,14”
From Effect of skin color on optical properties and the implications for medical optical technologies: a review (2024) · cites this paper as [13]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The physical and chemical properties of eumelanin
Meredith, P., & Sarna, T. (2006) · Pigment Cell Research · doi:10.1111/j.1600-0749.2006.00345.x · Cited by 1,033 · see citing works
A Chemist's View of Melanogenesis
Ito, S. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00037.x · Cited by 508 · see citing works
Kollias, N., Sayre, R. M., Zeise, L., & Chedekel, M. R. (1991) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(91)80147-a · Cited by 482 · see citing works
Photoprotection by melanin—a comparison of black and Caucasian skin
Kaidbey, K. H., Agin, P. P., Sayre, R. M., & Kligman, A. M. (1979) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(79)70018-1 · Cited by 467 · see citing works
A theoretical and experimental study of light absorption and scattering by in vivo skin
Dawson, J. B., Barker, D., Ellis, D. J., COTTERILL, J. A., Grassam, E., Fisher, G. W., & Feather, J. W. (1980) · Physics in Medicine and Biology · doi:10.1088/0031-9155/25/4/008 · Cited by 355 · see citing works
The pigments and color of living human skin
EDWARDS, E. A., & Duntley, S. Q. (1939) · American Journal of Anatomy · doi:10.1002/aja.1000650102 · Cited by 351 · see citing works
The supramolecular structure of melanin
Watt, A. A. R., Bothma, J. P., & Meredith, P. (2009) · Soft Matter · doi:10.1039/b902507c · Cited by 308 · see citing works
Subwavelength-resolution label-free photoacoustic microscopy of optical absorption in vivo
Zhang, C., Maslov, K., & Wang, L. V. (2010) · Optics Letters · doi:10.1364/ol.35.003195 · Cited by 281 · see citing works
Njoo, M. D., Das, P. K., Bos, J. D., et al. (1999) · Archives of Dermatology · doi:10.1001/archderm.135.4.407 · Cited by 265 · see citing works
Non‐Invasive Measurements of Skin Pigmentation In Situ
Stamatas, G. N., Zmudzka, B. Z., Kollias, N., & Beer, J. Z. (2004) · Pigment Cell Research · doi:10.1111/j.1600-0749.2004.00204.x · Cited by 225 · see citing works
308-nm Excimer Laser for the Treatment of Psoriasis
Asawanonda, P., Anderson, R. R., Chang, Y., & Taylor, C. R. (2000) · Archives of Dermatology · doi:10.1001/archderm.136.5.619 · Cited by 201 · see citing works
Accuracy of Self-report in Assessing Fitzpatrick Skin Phototypes I Through VI
Eilers, S., Bach, D. Q., Gaber, R., Blatt, H., Guevara, Y., Nitsche, K., Kundu, R. V., & Robinson, J. K. (2013) · JAMA Dermatology · doi:10.1001/jamadermatol.2013.6101 · Cited by 191 · see citing works
Matias, A. R., Ferreira, M., Costa, P. C., & Neto, P. (2015) · Skin Research and Technology · doi:10.1111/srt.12199 · Cited by 157 · see citing works
van der Wal, M., Bloemen, M., Verhaegen, P., Tuinebreijer, W., de Vet, H., van Zuijlen, P., & Middelkoop, E. (2013) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e318264bf7d · Cited by 96 · see citing works
The distribution of melanin in skin determined in vivo
Matts, P. J., Dykes, P. J., & Marks, R. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2006.07706.x · Cited by 96 · see citing works
Bhatnagar, A., Kanwar, A., Parsad, D., et al. (2007) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2007.02283.x · Cited by 94 · see citing works
Absorption Mechanisms of Human Melanin in the Visible, 400–720nm
Kollias, N., & Baqer, A. (1987) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12471764 · Cited by 91 · see citing works
ON THE ASSESSMENT OF MELANIN IN HUMAN SKIN in vivo*, †.
Kollias, N., & Baqer, A. (1986) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1986.tb05590.x · Cited by 91 · see citing works
Baquié, M., & Kasraee, B. (2013) · Skin Research and Technology · doi:10.1111/srt.12109 · Cited by 82 · see citing works
A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin
Mujahid, N., Liang, Y., Murakami, R., Choi, H. G., Dobry, A. S., Wang, J., Suita, Y., Weng, Q. Y., Allouche, J., Kemény, L. V., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.05.042 · Cited by 81 · see citing works
Treesirichod, A., Chansakulporn, S., & Wattanapan, P. (2014) · Indian Journal of Dermatology · doi:10.4103/0019-5154.135476 · Cited by 65 · see citing works
Design and evaluation of a novel portable erythema‐melanin‐meter
Dolotov, L. E., Sinichkin, Y. P., Tuchin, V. V., et al. (2004) · Lasers in Surgery and Medicine · doi:10.1002/lsm.10233 · Cited by 60 · see citing works
Kuchel, J. M., Barnetson, R. S., & Halliday, G. M. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01773.x · Cited by 47 · see citing works
Optical properties of melanin in the skin and skinlike phantoms
Bashkatov, A. N., Genina, E. A., Kochubey, V. I., Stolnitz, M. M., Bashkatova, T. A., Новикова, О. В., Peshkova, A. Y., & Tuchin, V. V. (2000) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.405946 · Cited by 46 · see citing works
Shin, J., Lee, D., Choi, S., et al. (2010) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2010.03815.x · Cited by 43 · see citing works
Modeling and Verification of Melanin Concentration on Human Skin Type
Karsten, A., & Smit, J. E. (2011) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2011.01044.x · Cited by 43 · see citing works
In vivo measurement of mid-infrared light scattering from human skin
Michel, A. P. M., Liakat, S., Bors, K. A., & Gmachl, C. F. (2013) · Biomedical Optics Express · doi:10.1364/boe.4.000520 · Cited by 43 · see citing works
The Chemical Structure of Melanin
Cheun, W. L. (2004) · Pigment Cell Research · doi:10.1111/j.1600-0749.2004.00165_1.x · Cited by 30 · see citing works
Skin image illumination modeling and chromophore identification for melanoma diagnosis
Liu, Z., & Zerubia, J. B. (2015) · Physics in Medicine and Biology · doi:10.1088/0031-9155/60/9/3415 · Cited by 28 · see citing works
Ha, T., Javedan, H., Waterston, K., Naysmith, L., & Rees, J. L. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00076.x · Cited by 27 · see citing works
Wright, C. Y., Karsten, A., Wilkes, M. M., Singh, A., du Plessis, J., Albers, P. N., & Karsten, P. A. (2016) · Photochemistry and Photobiology · doi:10.1111/php.12607 · Cited by 25 · see citing works
Verkruysse, W., Jia, W., Franco, W., Milner, T. E., & Nelson, J. S. (2007) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20581 · Cited by 24 · see citing works
Nakagawa, H., & Imokawa, G. (1996) · Pigment Cell Research · doi:10.1111/j.1600-0749.1996.tb00106.x · Cited by 15 · see citing works
Ash, C., Town, G., Bjerring, P., & Webster, S. (2014) · Photonics and Lasers in Medicine · doi:10.1515/plm-2013-0056 · Cited by 15 · see citing works
In vivo skin fluorescence imaging in young Caucasian adults with early malignant melanomas
Pierard, G., Piérard-Franchimont, C., Dewalque, L., Charlier, C., Hermanns‐Lê, T., Piérard, S. L., & Delvenne, P. (2014) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s66929 · Cited by 10 · see citing works
Remittance at a single wavelength of 390 nm to quantify epidermal melanin concentration
Verkruysse, W., Svaasand, L. O., Franco, W., et al. (2009) · Journal of Biomedical Optics · doi:10.1117/1.3065542 · Cited by 10 · see citing works
Shin, J. W., Yoon, S. W., Jeong, J. B., & Park, K. C. (2014) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12133 · Cited by 10 · see citing works
Thompson, M. J., Jones, G., & Aitken, D. A. (2018) · Osteoporosis International · doi:10.1007/s00198-018-4568-8 · Cited by 8 · see citing works
Optimized UVB treatment of psoriasis: a controlled, left‐right comparison trial
Selvaag, E., Caspersen, L., Bech-Thomsen, N., et al. (2000) · Journal of the European Academy of Dermatology and Venereology · doi:10.1046/j.1468-3083.2000.00012.x · Cited by 7 · see citing works
Correlating melanin index to repigmentation potential: A novel prognostic tool in vitiligo
Bhargava, P., Prakash, C., Tiwari, S., et al. (2016) · Pigment International · doi:10.4103/2349-5847.196296 · Cited by 4 · see citing works
Rakotomanga, P., Amouroux, M., Soussen, C., et al. (2018) · Biophotonics: Photonic Solutions for Better Health Care VI · doi:10.1117/12.2309516 · Cited by 4 · see citing works
Use of a modified Fitzpatrick scale in the understanding of skin cancer risk among people of color
(2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.04.1073 · Cited by 3 · see citing works
(2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.01.829 · Cited by 1 · see citing works
(2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.04.316 · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- ep12471764 · DOI
Cited by
Sorted by citations
Setchfield, K., Gorman, A., Simpson, A. H. R. W., Somekh, M. G., & Wright, A. J. (2024) · Journal of Biomedical Optics · doi:10.1117/1.jbo.29.1.010901 · Cited by 72 · see citing works
- Authors
- Kanellis, V. G.
- Affiliations
- Canberra Hospital (AU)
- Corresponding author
- Kanellis, Vangelis George
- Venue
- Biophysical Reviews
- Published
- 2019-08-08
- Volume
- 11
- Issue
- 6
- Pages
- 843-849
- ISSN
- 1867-2450 (ISSN-L)
- 1867-2469
- PMC
- PMC6874939
- OpenAlex
- W2967715215
- Cited by
- 29
- References
- 44
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 7 · 2023: 3 · 2022: 5 · 2021: 3 · 2020: 2 · 2019: 2
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Biophysical Reviews (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Keywords
- UV sensitivity, sunburn susceptibility, actinic skin damage, skin cancer prevention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review