Cited by 173Diabetes Management and EducationDiabetes, Cardiovascular Risks, and LipoproteinsPhysical Activity and Health

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A systematic review of the translational research on the Diabetes Prevention Program

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Whittemore, Robin·2011·Translational Behavioral Medicine

DOI 10.1007/s13142-011-0062-yPMC PMC3717627

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Abstract

International clinical trials have demonstrated compelling evidence on the prevention or delay of type 2 diabetes (T2D) by lifestyle change programs. Numerous studies have translated the Diabetes Prevention Program (DPP) protocol to "real-world" settings. The purpose of this paper is to review the translational research of the DPP protocol in adults at-risk for T2D. This study is a systematic review based on the guidelines from the Cochrane Handbook for Systematic Reviews. There were 16 studies that translated the DPP protocol in four distinct settings: (a) hospital outpatient, (b) primary care, (c) community, and (d) work and church. Settings varied considerably in terms of reach, efficacy, adoption, implementation, and maintenance. There were strengths and limitations to each setting. Better understanding of program adaptation and mediators and moderators to program efficacy are indicated. Future research also needs to continue to explore mechanisms to improve access and long-term outcomes.

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Translational Research
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Authors: Whittemore, R.
Affiliations: Yale University (US)
Corresponding author: Whittemore, Robin
ORCID: Whittemore, Robin
Venue: Translational Behavioral Medicine
Publisher: Oxford University Press (OUP)
Published: 2011-07-27
Volume: 1
Issue: 3
Pages: 480-491
ISSN: 1613-9860 (ISSN-L)
1869-6716
DOI: 10.1007/s13142-011-0062-y
PMC: PMC3717627
OpenAlex: W2003598964
Semantic Scholar: 72a25dde27dda64a0dc56139ea1bf6a71e009bfe
Cited by: 173
References: 54
Citations by year: 2026: 5 · 2025: 7 · 2024: 5 · 2023: 13 · 2022: 9 · 2021: 23 · 2020: 12 · 2019: 17 · 2018: 15 · 2017: 20 · 2016: 16 · 2015: 14 · 2014: 6 · 2013: 8 · 2012: 2
FWCI: 0.76
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Translational Behavioral Medicine (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Keywords: Diabetes Prevention Program, type 2 diabetes prevention, lifestyle intervention, program adaptation, real-world implementation, primary care, community settings, workplace health programs, church-based intervention, at-risk adults, program efficacy, mediators and moderators

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A systematic review of the translational research on the Diabetes Prevention Program

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