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Bioactive peptides of animal origin: a review
Open accessAbstract
Bioactive peptides are specific protein fragments which, above and beyond their nutritional capabilities, have a positive impact on the body's function or condition which may ultimately influence health. Although, inactive within the sequence of the parent proteins, these peptides can be released during proteolysis or fermentation and play an important role in human health by affecting the digestive, endocrine, cardiovascular, immune and nervous systems. Several peptides that are released in vitro or in vivo from animal proteins have been attributed to different health effects, including antimicrobial properties, blood pressure-lowering (ACE inhibitory) effects, cholesterol-lowering ability, antithrombotic and antioxidant activities, opioid activities, enhancement of mineral absorption and/or bioavailability, cytomodulatory and immunomodulatory effects, antiobesity, and anti-genotoxic activity. Several functional foods based on the bioactivities of these peptides with scientifically evidenced health claims are already on the market or under development by food companies. Consumer's increasing interest in these products has given an impetus to the food industry and scientific sector who are continuously exploring the possibilities for the development of new functional products based on these peptides. In this review, we describe above stated properties of bioactive peptides of animal origin.
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“Similar to dietary supplements, functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.114-121”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [119]
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Metadata
- Authors
- Bhat, Z. F., Kumar, S., & Bhat, H. F.
- Affiliations
- Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu (IN)
- Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (IN)
- Corresponding author
- Bhat, Z. F.
- Venue
- Journal of Food Science and Technology
- Published
- 2015-01-21
- Volume
- 52
- Issue
- 9
- Pages
- 5377-5392
- ISSN
- 0022-1155 (ISSN-L)
- 0975-8402
- PMC
- PMC4554628
- OpenAlex
- W2088757255
- Cited by
- 308
- References
- 177
- Citations by year
- 2026: 17 · 2025: 32 · 2024: 32 · 2023: 32 · 2022: 46 · 2021: 41 · 2020: 32 · 2019: 23 · 2018: 22 · 2017: 20 · 2016: 10 · 2015: 1
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Food Science and Technology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
- Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
- Keywords
- bioactive peptides, animal protein, proteolysis, fermentation, angiotensin-converting enzyme inhibition, blood pressure reduction, cholesterol lowering, antioxidant activity, antimicrobial peptides, opioid activity, mineral bioavailability, immunomodulation, anti-obesity, functional foods, health claims
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