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The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

The Use of Pharmacological Retromer Chaperones in Alzheimer's Disease and other Endosomal-related Disorders

Berman, Diego E., Ringe, Dagmar, Petsko, Greg A., Small, Scott A.·2015·Neurotherapeutics
DOI 10.1007/s13311-014-0321-y
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  • R55 enhances VPS35 assembly without affecting WASH binding.

    “Notably, R55 enhances VPS35 assembly without affecting WASH binding [4].”

    From Stabilizing the retromer complex rescues synaptic dysfunction and endosomal trafficking deficits in an Alzheimer’s disease mouse model (2025) · cites this paper as [4]

    The ‘Small Molecules as Retromer Chaperones’ section reports that R55 stabilizes the retromer complex and increases its levels in hippocampal neurons, supporting the assembly-related point. The ‘Retromer in Other Diseases’ section discusses impaired WASH binding caused by a VPS35 mutation, but does not say whether R55 affects WASH binding. Page numbers were not provided in our copy. (LLM, conf=0.85)

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Research works printed but not linked: 36

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  4. Small, 2006, Sorting through the cell biology of Alzheimer's disease: intracellular pathways to neurogenesis, Neuron, 52, 15, 10.1016/j.neuron.2006.09.001 · DOI
  5. Bhalla, 2012, The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport, Neurobiol Dis, 47, 126, 10.1016/j.nbd.2012.03.030 · DOI · Paper page
  6. Choy, 2012, Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network, Proc Natl Acad Sci U S A, 109, 2077, 10.1073/pnas.1208635109 · DOI
  7. Prabhu, 2012, Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing, Mol Biol Cell, 23, 2339, 10.1091/mbc.e11-11-0944 · DOI · Paper page
  8. Andersen, 2005, Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein, Proc Natl Acad Sci U S A, 102, 13461, 10.1073/pnas.0503689102 · DOI · Paper page
  9. Rogaeva, 2007, The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease, Nat Genet, 39, 168, 10.1038/ng1943 · DOI · Paper page
  10. Seaman, 1997, Endosome to golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products, J Cell Biol, 137, 79, 10.1083/jcb.137.1.79 · DOI · Paper page
  11. Bonifacino, 2008, Retromer, Curr Opin Cell Biol, 20, 427, 10.1016/j.ceb.2008.03.009 · DOI · Paper page
  12. Attar, 2010, The retromer complex, Adv Enzym Regul, 50, 216, 10.1016/j.advenzreg.2009.10.002 · DOI
  13. Small, 2005, Model-guided microarray implicates the retromer complex in Alzheimer's disease, Ann Neurol, 58, 909, 10.1002/ana.20667 · DOI · Paper page
  14. Ringe, 2009, What are pharmacological chaperones and why are they interesting?, J Biol, 8, 80, 10.1186/jbiol186 · DOI
  15. Small, 2014, Pharmacological chaperones in the age of proteomic pathology, Proc Natl Acad Sci U S A, 111, 12274, 10.1073/pnas.1413111111 · DOI
  16. Oh, 2014, Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein, Proc Natl Acad Sci U S A, 111, 11007, 10.1073/pnas.1320556111 · DOI
  17. Mecozzi, 2014, Pharmacological chaperones stabilize retromer to limit APP processing, Nat Chem Biol, 10, 443, 10.1038/nchembio.1508 · DOI · Paper page
  18. Guerreiro, 2013, TREM2 variants in Alzheimer's disease, N Engl J Med, 368, 117, 10.1056/NEJMoa1211851 · DOI · Paper page
  19. Shannon, 2014, Genetic variation of the retromer subunits VPS26A/B-VPS29 in Parkinson's disease, Neurobiol Aging, 35, 1958, 10.1016/j.neurobiolaging.2014.03.004 · DOI · Paper page
  20. MacLeod, 2013, RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk, Neuron, 77, 425, 10.1016/j.neuron.2012.11.033 · DOI · Paper page
  21. Zavodszky, 2014, Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy, Nat Commun, 13, 3828, 10.1038/ncomms4828 · DOI · Paper page
  22. Wang, 2014, In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila, Mol Brain, 7, 73, 10.1186/s13041-014-0073-y · DOI
  23. Zavodszky, 2014, VPS35 Parkinson mutation impairs autophagy via WASH, Cell Cycle, 13, 2155, 10.4161/cc.29734 · DOI
  24. Vilariño-Güell, 2011, VPS35 mutations in Parkinson disease, Am J Hum Genet, 89, 162, 10.1016/j.ajhg.2011.06.001 · DOI · Paper page
  25. Wang, 2013, Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome, Nat Med, 19, 473, 10.1038/nm.3117 · DOI · Paper page
  26. Jones, 2013, Sorting receptors at Down's syndrome synapses, Nat Med, 1, 404, 10.1038/nm.3152 · DOI
  27. Mamo, 2012, The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting, Mol Cell Biol, 32, 1855, 10.1128/MCB.06726-11 · DOI · Paper page
  28. Goold, 2013, Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane, J Cell Sci, 126, 3552
  29. Du, 2012, An essential role of Hrs/Vps27 in endosomal cholesterol trafficking, Cell Rep, 1, 29, 10.1016/j.celrep.2011.10.004 · DOI
  30. Lane, 2012, Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes, J Neurosci, 32, 14080, 10.1523/JNEUROSCI.3359-12.2012 · DOI
  31. Moriboto, 2014, Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease, Neurobiol Dis, 65, 188, 10.1016/j.nbd.2013.12.017 · DOI
  32. Xia, 2013, Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling, J Cell Biol, 200, 821, 10.1083/jcb.201207154 · DOI
  33. Liu, 2014, Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis, Mol Brain, 7, 10, 10.1186/1756-6606-7-10 · DOI
  34. Finsel, 2013, The Legionella effector RidL inhibits retrograde trafficking to promote intracellular replication, Cell Host Microbe, 14, 38, 10.1016/j.chom.2013.06.001 · DOI
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Metadata

Authors
Berman, D. E., Ringe, D., Petsko, G. A., & Small, S. A.
Venue
Neurotherapeutics
Publisher
Elsevier BV
Published
2015-01
Volume
12
Issue
1
Pages
12-18
ISSN
1878-7479
DOI
10.1007/s13311-014-0321-y
Cited by
35
References
7
Language
en
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