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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

MacLeod, David A., Rhinn, Herve, Kuwahara, Tomoki, Zolin, Ari, Di Paolo, Gilbert, McCabe, Brian D., Marder, Karen S., Honig, Lawrence S., Clark, Lorraine N., Small, Scott A., Abeliovich, Asa·2013·Neuron
DOI 10.1016/j.neuron.2012.11.033PMC PMC3646583
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  • The endosomal network is a key biological pathway affected in neurodegenerative pathology.

    “These studies, alongside clinical evidence [8][9][10][11][12][13][14], highlight the endosomal network as a key biological pathway affected in neurodegenerative pathology.”

    From Global identification of neuronal and astrocytic integral membrane proteins that require Retromer for their endosomal recycling (2026) · cites this paper as [10]

  • Variants within the RAB29 and LRRK2 loci seem to impact Parkinson's disease in a non-additive manner, suggesting the two proteins function in a common cellular pathway.

    “Variants within the RAB29 and the LRRK2 locus seem to impact PD in a non-additive manner [22,49,53], suggesting that the two proteins function in a common cellular pathway.”

    From Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations (2020) · cites this paper as [22]

  • Previous studies report a beneficial effect of increasing RAB29 protein levels on Golgi-lysosome sorting events, neurite outgrowth, and dopaminergic cell survival in Drosophila neurons.

    “This finding is consistent with previous studies reporting a beneficial effect of increasing RAB29 protein levels on Golgi-lysosome sorting events, neurite outgrowth, and dopaminergic cell survival in Drosophila neurons, and with transcriptome analysis suggesting that RAB29 risk variants correlate with a decrease in RAB29 expression levels [22].”

    From Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations (2020) · cites this paper as [22]

  • Knockdown or knockout of RAB29 causes deficits in retrograde sorting events between the late endosome and the Golgi complex, which is crucial for the correct trafficking of lysosomal enzymes and associated with defects in lysosomal homeostasis.

    “However, knockdown or knockout of RAB29 causes deficits in retrograde sorting events between the late endosome and the Golgi complex, which is crucial for the correct trafficking of lysosomal enzymes and associated with defects in lysosomal homeostasis [22,27,74].”

    From Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations (2020) · cites this paper as [22]

  • Transcriptome analysis suggests that RAB29 risk variants correlate with a decrease in RAB29 expression levels.

    “and with transcriptome analysis suggesting that RAB29 risk variants correlate with a decrease in RAB29 expression levels [22].”

    From Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations (2020) · cites this paper as [22]

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Research works printed but not linked: 45

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  18. Hermann, 2005, Genetic analysis of lysosomal trafficking in Caenorhabditis elegans, Mol. Biol. Cell, 16, 3273, 10.1091/mbc.e05-01-0060 · DOI
  19. Higashi, 2009, Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in Lewy body disease, J. Neuropathol. Exp. Neurol., 68, 994, 10.1097/NEN.0b013e3181b44ed8 · DOI
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  23. Li, 2009, Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson’s disease, Nat. Neurosci., 12, 826, 10.1038/nn.2349 · DOI
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Metadata

Authors
MacLeod, D. A., Rhinn, H., Kuwahara, T., Zolin, A., Di Paolo, G., McCabe, B. D., Marder, K. S., Honig, L. S., Clark, L. N., Small, S. A., & Abeliovich, A.
Venue
Neuron
Publisher
Elsevier BV
Published
2013-02
Volume
77
Issue
3
Pages
425-439
ISSN
0896-6273
DOI
10.1016/j.neuron.2012.11.033
PMC
PMC3646583
Cited by
516
References
3
Language
en
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