Cited by 216Circadian rhythm and melatoninSleep and Wakefulness ResearchHypothalamic control of reproductive hormones

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A fine-grained anatomical analysis of the role of the rat suprachiasmatic nucleus in circadian rhythms of feeding and drinking

Van Den Pol, Anthony N., Powley, Terry·1979·Brain Research

DOI 10.1016/0006-8993(79)90427-x

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Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat
Moore, R. Y., & Eichler, V. B. (1972) · Brain Research · doi:10.1016/0006-8993(72)90054-6 · Cited by 2,135
Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions
Stephan, F. K., & Zucker, I. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1583 · Cited by 2,039
A Method for the Combined Staining of Cells and Fibers in the Nervous System
Klüver, H., & Barrera, E. (1953) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-195312040-00008 · Cited by 1,724
A retinohypothalamic projection in the rat
Moore, R. Y., & Lenn, N. J. (1972) · The Journal of Comparative Neurology · doi:10.1002/cne.901460102 · Cited by 1,263
Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity
Moore, R. Y., & Klein, D. C. (1974) · Brain Research · doi:10.1016/0006-8993(74)90188-7 · Cited by 678
An autoradiographic and electron microscopic study of retino-hypothalamic connections
Hendrickson, A. E., Wagoner, N. E., & Cowan, W. M. (1972) · Cell and Tissue Research · doi:10.1007/bf00307084 · Cited by 490
HYPOTHALAMIC CONTROL OF THE ANTERIOR PITUITARY
Pickford, M. (1963) · Quarterly Journal of Experimental Physiology and Cognate Medical Sciences · doi:10.1113/expphysiol.1963.sp001653 · Cited by 490
Advances in Neuroendocrinology.
Brodish, A. (1963) · JAMA · doi:10.1001/jama.1963.03710120088037 · Cited by 480
Retinohypothalamic projection in mammals: a comparative study
Moore, R. Y. (1973) · Brain Research · doi:10.1016/0006-8993(73)90431-9 · Cited by 477
Animal behavior and internal drives.
Richter, C. P. (1927) · The Quarterly Review of Biology · doi:10.1086/394279 · Cited by 474

Show all 39 references

Research works printed but not linked: 3

Fischette, 1977, The effect of differential fornix ablations on the circadian rhythmicity of adrenal corticosteroids, Neurosci. Abstr., 3, 343
Fuxe, 1965, Distribution of monoamine nerve terminals in the central nervous system, Acta Physiol. scand., 64
Richter, 1967, Sleep and activity: their relation to the 24-hour clock. Sleep and Altered States of Consciousness, A.R.N.M.D., 45, 8

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Background
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Background
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Vilaplana, J., & Lavialle, M. (1999) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(99)00016-3 · Cited by 64
Circadian Locomotor Rhythms, but Not Photoperiodic Responses, Survive Surgical Isolation of the SCN in Hamsters
Hakim, H., DeBernardo, A. P., & Silver, R. (1991) · Journal of Biological Rhythms · doi:10.1177/074873049100600201 · Cited by 60
Chapter 10 The human hypothalamus: comparative morphometry and photoperiodic influences
Hofman, M. A., & Swaab, D. F. (1992) · Progress in brain research · doi:10.1016/s0079-6123(08)64569-0 · Cited by 64
Circadian rhythms
Aronson, B. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90015-r · Cited by 61
Does the ventromedial hypothalamic nucleus contain a self-sustained circadian oscillator associated with periodic feedings?
Inouye, S. T. (1983) · Brain Research · doi:10.1016/0006-8993(83)90162-2 · Cited by 60
Projections from the lateral geniculate nucleus to the hypothalamus of the mongolian gerbil (Meriones unguiculatus): An anterograde and retrograde tracing study
Mikkelsen, J. D. (1990) · The Journal of comparative neurology · doi:10.1002/cne.902990409 · Cited by 60
Circadian changes in arginine vasopressin level in the suprachiasmatic nuclei in the rat
Yamase, K., Takahashi, S., Nomura, K., Haruta, K., & Kawashima, S. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90409-m · Cited by 57
Effects of partial destruction of the suprachiasmatic nuclei on two circadian parameters: wheel-running activity and short-day induced testicular regression
Pickard, G. E., & Turek, F. (1985) · Journal of Comparative Physiology · doi:10.1007/bf00610832 · Cited by 22
Circadian rhythms of somatostatin-immunoreactivity in the suprachiasmatic nucleus of the rat
Shinohara, K., Isobe, Y., Takeuchi, J., & Inouye, S. T. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90720-e · Cited by 56
Circadian rhythms of hedonic drinking behavior in mice
Bainier, C., Mateo, M., Felder‐Schmittbuhl, M., & Mendoza, J. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.03.002 · Cited by 53
Circadian integration of sleep-wake and feeding requires NPY receptor-expressing neurons in the mediobasal hypothalamus
Wiater, M. F., Mukherjee, S., Li, A.-J., Dinh, T. T. N., Rooney, E., Simasko, S. M., & Ritter, S. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00168.2011 · Cited by 55
Restoration of Circadian Rhythmicity by Transplants of SCN "Micropunches"
LeSauter, J., Lehman, M., & Silver, R. (1996) · Journal of Biological Rhythms · doi:10.1177/074873049601100208 · Cited by 56
Effect of suprachiasmatic nucleus lesion on circadian dentin increment in rats
Ohtsuka‐Isoya, M., Hayashi, H., & Shinoda, H. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.5.r1364 · Cited by 54
Nuclear mechanisms mediate rhythmic changes in vasopressin mRNA expression in the rat suprachiasmatic nucleus
Carter, D., & Murphy, D. (1992) · Molecular Brain Research · doi:10.1016/0169-328x(92)90133-v · Cited by 54

Authors: Van Den Pol, A. N., & Powley, T.
Affiliations: Yale University (US)
ORCID: Powley, Terry
Venue: Brain Research
Publisher: Elsevier BV
Published: 1979-01
Volume: 160
Issue: 2
Pages: 307-326
ISSN: 0006-8993 (ISSN-L)
DOI: 10.1016/0006-8993(79)90427-x
OpenAlex: W1981206448
Cited by: 216
References: 39
Citations by year: 2026: 3 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 2 · 2018: 5 · 2017: 3 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 1 · 2012: 3
FWCI: 10.73
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Brain Research (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Keywords: suprachiasmatic nucleus, circadian rhythm, feeding behavior, drinking behavior, radiofrequency lesions, lesion size, ultradian rhythms, autocorrelation coefficient, light-dark ratio
MeSH terms: Animals, Brain Mapping, Circadian Rhythm, Computers, Drinking Behavior, Feeding Behavior, Hypothalamus, Hypothalamus, Middle, Male, Optic Chiasm, Rats, Inbred Strains, Sensory Deprivation, Rats

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A fine-grained anatomical analysis of the role of the rat suprachiasmatic nucleus in circadian rhythms of feeding and drinking

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