The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Cloning and functional characterization of a cocaine‐sensitive dopamine transporter
Open accessAbstract
We report the cloning of a rat cDNA encoding a functional dopamine transporter. This cDNA, derived from an intron‐containing gene, encodes a protein of 620 amino acids. Hydropathicity analysis of the protein sequence suggests the presence of 12 putative transmembrane domains. The protein displays considerable identity with transporters for noradrenaline and GABA (64 and 30%, respectively). Transient expression of the cDNA in COS7 cells directs the expression of dopamine uptake activity with appropriate pharmacology and in a sodium‐dependent fashion. In situ hybridization reveals that the mRNA for this transporter is expressed in the substantia nigra and ventral tegmental area, regions that contain dopaminergic cell bodies.
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Cites
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90021-2 · Cited by 46,426
LIGAND: A versatile computerized approach for characterization of ligand-binding systems
Munson, P. J., & Rodbard, D. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90515-1 · Cited by 8,429
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
Kozak, M. (1987) · Nucleic Acids Research · doi:10.1093/nar/15.20.8125 · Cited by 5,087
Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
Ritz, M. C., Lamb, R. J., Goldberg, S. R., & Kuhar, M. J. (1987) · Science · doi:10.1126/science.2820058 · Cited by 2,180
Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
Pacholczyk, T., Blakely, R. D., & Amara, S. G. (1991) · Nature · doi:10.1038/350350a0 · Cited by 933
Cloning and Expression of a Rat Brain GABA Transporter
Guastella, J., Nelson, N., Nelson, H., Czyzyk, L., Keynan, S., Miedel, M. C., Davidson, N., Lester, H. A., & Kanner, B. I. (1990) · Science · doi:10.1126/science.1975955 · Cited by 879
Alternative splicing directs the expression of two D2 dopamine receptor isoforms
Giros, B., Sokoloff, P., Martres, M.-P., Riou, J.-F., Emorine, L. J., & Schwartz, J.-C. (1989) · Nature · doi:10.1038/342923a0 · Cited by 685
Self-citationMolecular cloning and expression of the gene for a human D1 dopamine receptor
Dearry, A., Gingrich, J. A., Falardeau, P., Fremeau, R. T., Bates, M. D., & Caron, M. G. (1990) · Nature · doi:10.1038/347072a0 · Cited by 674
Self-citationP‐glycoprotein: multidrug‐resistance and a superfamily of membrane‐associated transport proteins
Juranka, P. F., Zastawny, R. L., & Ling, V. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.14.2574119 · Cited by 503
Fremeau, R. T., Duncan, G. E., Fornaretto, M. G., Dearry, A., Gingrich, J. A., Breese, G. R., & Caron, M. G. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.9.3772 · Cited by 354
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Cited by
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
Giros, B., Jaber, M., Jones, S. R., Wightman, R. M., & Caron, M. G. (1996) · Nature · doi:10.1038/379606a0 · Cited by 2,476
Self-citationDopamine as a Prolactin (PRL) Inhibitor
Ben-Jonathan, N., & Hnasko, R. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.6.0451 · Cited by 983
Plasma membrane monoamine transporters: structure, regulation and function
Torres, G. E., Gainetdinov, R. R., & Caron, M. G. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1008 · Cited by 939
Self-citationA cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
Liu, Y. (1992) · Cell · doi:10.1016/0092-8674(92)90425-c · Cited by 594
Glycine transporters are differentially expressed among CNS cells
Zafra, F., Aragon, C., Olivares, L., Danbolt, N., Gimenez, C., & Storm-Mathisen, J. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03952.1995 · Cited by 521
Metadata
- Authors
- Giros, B., El Mestikawy, S., Bertrand, L., & Caron, M. G.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1991-12-16
- Volume
- 295
- Issue
- 1-3
- Pages
- 149-154
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2003266390
- Cited by
- 368
- References
- 21
- FWCI
- 7.35
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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