Control of the transport of reducing equivalents across the mitochondrial membrane in perfused rat heart

Safer, B

doi:10.1016/0022-2828(71)90065-4

Cited by 118Mitochondrial Function and PathologyBiochemical Acid Research StudiesCardiac Ischemia and Reperfusion

Control of the transport of reducing equivalents across the mitochondrial membrane in perfused rat heart

Safer, B·1971·Journal of Molecular and Cellular Cardiology

DOI 10.1016/0022-2828(71)90065-4

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The glycerol 3-phosphate shuttle is not considered the major route of NADH shuttling in most mammalian cells but is particularly active in brown adipose tissue and may be implicated in thermoregulation.
“The glycerol 3-phosphate shuttle is not considered the major route of NADH shuttling in most mammalian cells but has been shown to be particularly active in brown adipose tissue and may be implicated in thermoregulation (105, 106, 107).”
From Regulation and function of the mammalian tricarboxylic acid cycle (2023) · cites this paper as [107]

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Authors: Safer, B.
Affiliations: University of Pennsylvania (US)
Corresponding author: Safer, B
Venue: Journal of Molecular and Cellular Cardiology
Publisher: Elsevier BV
Published: 1971-06
Volume: 2
Issue: 2
Pages: 111-124
ISSN: 0022-2828 (ISSN-L)
DOI: 10.1016/0022-2828(71)90065-4
OpenAlex: W2024564250
Cited by: 118
References: 38
Citations by year: 2026: 2 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 1 · 2012: 1
FWCI: 3.51
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Molecular and Cellular Cardiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Biochemical Acid Research Studies
Health Sciences › Medicine › Pathology and Forensic Medicine › Cardiac Ischemia and Reperfusion
Keywords: malate-aspartate shuttle, NADH reoxidation, aspartate aminotransferase, aminooxyacetic acid, triiodothyronine, citric acid cycle intermediates, alanine aminotransferase, lactate oxidation, glucose oxidation, rat heart
MeSH terms: Alanine Transaminase, Animals, Antimetabolites, Aspartate Aminotransferases, Biological Transport, Citric Acid Cycle, Glucose, Glycerophosphates, Glycolates, Heart, Homeostasis, Lactates, Malates, Male, Mitochondria, Muscle, Myocardium, NAD, Oxidation-Reduction, Perfusion, Triiodothyronine, Rats

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