The plasma concentration of oestrone sulphate in postmenopausal women: lack of diurnal variation, effect of ovariectomy, age and weight
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Theca cells express high levels of estrogen sulfotransferase SULT1E1, which preferentially sulfates estrone yielding relatively abundant estrone sulfate measured in circulation.
“Theca cells also express high levels of the estrogen sulfotransferase enzyme SULT1E1, which preferentially sulfates estrone yielding the relatively abundant estrone sulfate measured in circulation [[82], [83], [84]].”
From Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review (2019) · cites this paper as [82]
The primary estrogens in circulation are estrone, estrone sulfate and 17β-estradiol, with 17β-estradiol considered the biologically active form.
“The primary estrogens in circulation are estrone, estrone sulfate and 17β-estradiol, with 17β-estradiol considered the biologically active form [82,[301], [302], [303]].”
From Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review (2019) · cites this paper as [82]
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Self-citationBindingDB (2017) · UC San Diego · doi:10.7270/q26q2048
- Authors
- Noel, C. T., Reed, M. J., Jacobs, H. S., & James, V. H. T.
- Affiliations
- St Mary's Hospital (GB)
- ORCID
- Jacobs, H.S.
- Venue
- Journal of Steroid Biochemistry
- Publisher
- Elsevier BV
- Published
- 1981-11
- Volume
- 14
- Issue
- 11
- Pages
- 1101-1105
- ISSN
- 0022-4731 (ISSN-L)
- OpenAlex
- W1996057873
- Cited by
- 94
- References
- 11
- Citations by year
- 2025: 1 · 2021: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 3
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Steroid Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- estrone sulfate, postmenopausal women, plasma steroid levels, diurnal variation, ovariectomy, body weight, obesity, age
- MeSH terms
- Aged, Aging, Castration, Circadian Rhythm, Estrone, Female, Humans, Male, Menopause, Middle Aged, Obesity, Radioimmunoassay
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