Cited by 86Estrogen and related hormone effectsHypothalamic control of reproductive hormonesNeuroscience and Neuropharmacology Research

The cellular effects of estrogens on neuroendocrine tissues

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Naftolin, F., Maclusky, N.J., Leranth, C.Z., Sakamoto, H.S., Garcia-Segura, L.M.·1988·Journal of Steroid Biochemistry

Abstract

Estrogen action on sensitive neurons in the rat diencephalon has been studied by morphologic techniques; evidence of estrogen action at every level is presented, including tracts, cells, circuitry and subcellular organelles. The demonstration in the arcuate nucleus of estrogen-induced synaptic remodelling, estrogen-induced postsynaptic membrane phenotypes, changes in intracellular membranes and rapid estrogen actions on neuronal endo-exocytosis indicates that cellular estrogen actions may underlie the neuronal control of reproduction.

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Crossref · 10.1016/0022-4731(88)90093-3

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97 of 97 references verified0 citation errors · 0 not checkable

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  • Estrogen exerts a negative feedback on the hypothalamic-pituitary axis and decreases the release of FSH from the pituitary gland.

    “Estrogen exerts a negative feedback on the hypothalamicpituitary axis and decreases the release of FSH from the pituitary gland (42)(43)(44)(45)(46).”

    From A new era in ovulation induction (2006) · cites this paper as [45]

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Authors
Naftolin, F., Maclusky, N. J., Leranth, C. Z., Sakamoto, H. S., & Garcia-Segura, L. M.
Affiliations
Yale University (US)
Corresponding author
Naftolin, F.
Venue
Journal of Steroid Biochemistry
Publisher
Elsevier BV
Published
1988
Volume
30
Issue
1-6
Pages
195-207
ISSN
0022-4731 (ISSN-L)
OpenAlex
W1972516854
Cited by
86
References
97
Citations by year
2025: 1 · 2022: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2013: 1 · 2012: 2
FWCI
1.26
Type
journal article
Language
en
Open access
Locations
  • Journal of Steroid Biochemistry (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 13587)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
  • Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
estrogen, neuroendocrine tissues, diencephalon, arcuate nucleus, synaptic remodeling, postsynaptic membrane, intracellular membranes, neuronal exocytosis
MeSH terms
Animals, Brain, Estrogens, Female, Male, Models, Biological, Neurons, Neurosecretory Systems

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